A citation-based method for searching scientific literature

L HAYFLICK. Exp Cell Res 1965
Times Cited: 4279







List of co-cited articles
991 articles co-cited >1



Times Cited
  Times     Co-cited
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Discovery of piperlongumine as a potential novel lead for the development of senolytic agents.
Yingying Wang, Jianhui Chang, Xingui Liu, Xuan Zhang, Suping Zhang, Xin Zhang, Daohong Zhou, Guangrong Zheng. Aging (Albany NY) 2016
93
7

A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen.
Jean-Philippe Coppé, Christopher K Patil, Francis Rodier, Ana Krtolica, Christian M Beauséjour, Simona Parrinello, J Graeme Hodgson, Koei Chin, Pierre-Yves Desprez, Judith Campisi. PLoS One 2010
247
7

Unmasking senescence: context-dependent effects of SASP in cancer.
Douglas V Faget, Qihao Ren, Sheila A Stewart. Nat Rev Cancer 2019
121
7

Cellular senescence in aging primates.
Utz Herbig, Mark Ferreira, Laura Condel, Dee Carey, John M Sedivy. Science 2006
665
7

Tau protein aggregation is associated with cellular senescence in the brain.
Nicolas Musi, Joseph M Valentine, Kathryn R Sickora, Eric Baeuerle, Cody S Thompson, Qiang Shen, Miranda E Orr. Aging Cell 2018
128
7

Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan.
Laurent Grosse, Nicole Wagner, Alexander Emelyanov, Clement Molina, Sandra Lacas-Gervais, Kay-Dietrich Wagner, Dmitry V Bulavin. Cell Metab 2020
42
16

Mitochondria are required for pro-ageing features of the senescent phenotype.
Clara Correia-Melo, Francisco D M Marques, Rhys Anderson, Graeme Hewitt, Rachael Hewitt, John Cole, Bernadette M Carroll, Satomi Miwa, Jodie Birch, Alina Merz,[...]. EMBO J 2016
254
7

Cellular Senescence Is Induced by the Environmental Neurotoxin Paraquat and Contributes to Neuropathology Linked to Parkinson's Disease.
Shankar J Chinta, Georgia Woods, Marco Demaria, Anand Rane, Ying Zou, Amanda McQuade, Subramanian Rajagopalan, Chandani Limbad, David T Madden, Judith Campisi,[...]. Cell Rep 2018
139
7

NOTCH1 mediates a switch between two distinct secretomes during senescence.
Matthew Hoare, Yoko Ito, Tae-Won Kang, Michael P Weekes, Nicholas J Matheson, Daniel A Patten, Shishir Shetty, Aled J Parry, Suraj Menon, Rafik Salama,[...]. Nat Cell Biol 2016
167
7

Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging.
A Krtolica, S Parrinello, S Lockett, P Y Desprez, J Campisi. Proc Natl Acad Sci U S A 2001
981
7

Targeting senescent cells alleviates obesity-induced metabolic dysfunction.
Allyson K Palmer, Ming Xu, Yi Zhu, Tamar Pirtskhalava, Megan M Weivoda, Christine M Hachfeld, Larissa G Prata, Theo H van Dijk, Esther Verkade, Grace Casaclang-Verzosa,[...]. Aging Cell 2019
127
7

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis.
Zhenbang Chen, Lloyd C Trotman, David Shaffer, Hui-Kuan Lin, Zohar A Dotan, Masaru Niki, Jason A Koutcher, Howard I Scher, Thomas Ludwig, William Gerald,[...]. Nature 2005
6

Cell fusion induced by ERVWE1 or measles virus causes cellular senescence.
Anna Chuprin, Hilah Gal, Tal Biron-Shental, Anat Biran, Aliza Amiel, Shmuel Rozenblatt, Valery Krizhanovsky. Genes Dev 2013
115
6

p16(Ink4a)-induced senescence of pancreatic beta cells enhances insulin secretion.
Aharon Helman, Agnes Klochendler, Narmen Azazmeh, Yael Gabai, Elad Horwitz, Shira Anzi, Avital Swisa, Reba Condiotti, Roy Z Granit, Yuval Nevo,[...]. Nat Med 2016
132
6

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.
Jan R Dörr, Yong Yu, Maja Milanovic, Gregor Beuster, Christin Zasada, J Henry M Däbritz, Jan Lisec, Dido Lenze, Anne Gerhardt, Katharina Schleicher,[...]. Nature 2013
278
6

Cytoplasmic chromatin triggers inflammation in senescence and cancer.
Zhixun Dou, Kanad Ghosh, Maria Grazia Vizioli, Jiajun Zhu, Payel Sen, Kirk J Wangensteen, Johayra Simithy, Yemin Lan, Yanping Lin, Zhuo Zhou,[...]. Nature 2017
352
6

Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression.
Tobias Eggert, Katharina Wolter, Juling Ji, Chi Ma, Tetyana Yevsa, Sabrina Klotz, José Medina-Echeverz, Thomas Longerich, Marshonna Forgues, Florian Reisinger,[...]. Cancer Cell 2016
176
6

A crucial role for adipose tissue p53 in the regulation of insulin resistance.
Tohru Minamino, Masayuki Orimo, Ippei Shimizu, Takeshige Kunieda, Masataka Yokoyama, Takashi Ito, Aika Nojima, Akira Nabetani, Yuichi Oike, Hisahiro Matsubara,[...]. Nat Med 2009
463
6

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts.
D A Alcorta, Y Xiong, D Phelps, G Hannon, D Beach, J C Barrett. Proc Natl Acad Sci U S A 1996
706
6

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome.
Shin Yoshimoto, Tze Mun Loo, Koji Atarashi, Hiroaki Kanda, Seidai Sato, Seiichi Oyadomari, Yoichiro Iwakura, Kenshiro Oshima, Hidetoshi Morita, Masahira Hattori,[...]. Nature 2013
991
6

BRAFE600-associated senescence-like cell cycle arrest of human naevi.
Chrysiis Michaloglou, Liesbeth C W Vredeveld, Maria S Soengas, Christophe Denoyelle, Thomas Kuilman, Chantal M A M van der Horst, Donné M Majoor, Jerry W Shay, Wolter J Mooi, Daniel S Peeper. Nature 2005
6

Chemical screening identifies ATM as a target for alleviating senescence.
Hyun Tae Kang, Joon Tae Park, Kobong Choi, Yongsub Kim, Hyo Jei Claudia Choi, Chul Won Jung, Young-Sam Lee, Sang Chul Park. Nat Chem Biol 2017
61
9

Cell surface-bound IL-1alpha is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network.
Arturo V Orjalo, Dipa Bhaumik, Bridget K Gengler, Gary K Scott, Judith Campisi. Proc Natl Acad Sci U S A 2009
332
6

Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence.
Selene Glück, Baptiste Guey, Muhammet Fatih Gulen, Katharina Wolter, Tae-Won Kang, Niklas Arndt Schmacke, Anne Bridgeman, Jan Rehwinkel, Lars Zender, Andrea Ablasser. Nat Cell Biol 2017
324
6

The DNA-damage response in human biology and disease.
Stephen P Jackson, Jiri Bartek. Nature 2009
6

Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice.
Carolyn M Roos, Bin Zhang, Allyson K Palmer, Mikolaj B Ogrodnik, Tamar Pirtskhalava, Nassir M Thalji, Michael Hagler, Diana Jurk, Leslie A Smith, Grace Casaclang-Verzosa,[...]. Aging Cell 2016
274
6

Non-cell-autonomous tumor suppression by p53.
Amaia Lujambio, Leila Akkari, Janelle Simon, Danielle Grace, Darjus F Tschaharganeh, Jessica E Bolden, Zhen Zhao, Vishal Thapar, Johanna A Joyce, Valery Krizhanovsky,[...]. Cell 2013
395
6

Inflammatory networks during cellular senescence: causes and consequences.
Adam Freund, Arturo V Orjalo, Pierre-Yves Desprez, Judith Campisi. Trends Mol Med 2010
684
6

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
David E Harrison, Randy Strong, Zelton Dave Sharp, James F Nelson, Clinton M Astle, Kevin Flurkey, Nancy L Nadon, J Erby Wilkinson, Krystyna Frenkel, Christy S Carter,[...]. Nature 2009
6

Spatial coupling of mTOR and autophagy augments secretory phenotypes.
Masako Narita, Andrew R J Young, Satoko Arakawa, Shamith A Samarajiwa, Takayuki Nakashima, Sei Yoshida, Sungki Hong, Lorraine S Berry, Stefanie Reichelt, Manuela Ferreira,[...]. Science 2011
331
6

Glucocorticoids suppress selected components of the senescence-associated secretory phenotype.
Remi-Martin Laberge, Lili Zhou, Melissa R Sarantos, Francis Rodier, Adam Freund, Peter L J de Keizer, Su Liu, Marco Demaria, Yu-Sheng Cong, Pankaj Kapahi,[...]. Aging Cell 2012
112
6

cGAS is essential for cellular senescence.
Hui Yang, Hanze Wang, Junyao Ren, Qi Chen, Zhijian J Chen. Proc Natl Acad Sci U S A 2017
321
6

Spatial and Temporal Control of Senescence.
Yoko Ito, Matthew Hoare, Masashi Narita. Trends Cell Biol 2017
52
11

Tumor Cell Escape from Therapy-Induced Senescence as a Model of Disease Recurrence after Dormancy.
Tareq Saleh, Liliya Tyutyunyk-Massey, David A Gewirtz. Cancer Res 2019
49
12

Therapy-induced senescence in cancer.
Jonathan A Ewald, Joshua A Desotelle, George Wilding, David F Jarrard. J Natl Cancer Inst 2010
408
6

Targeting senescent cells enhances adipogenesis and metabolic function in old age.
Ming Xu, Allyson K Palmer, Husheng Ding, Megan M Weivoda, Tamar Pirtskhalava, Thomas A White, Anna Sepe, Kurt O Johnson, Michael B Stout, Nino Giorgadze,[...]. Elife 2015
218
6

DNA damage response and cellular senescence in tissues of aging mice.
Chunfang Wang, Diana Jurk, Mandy Maddick, Glyn Nelson, Carmen Martin-Ruiz, Thomas von Zglinicki. Aging Cell 2009
380
6

Mammalian telomeres end in a large duplex loop.
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
5

Autophagy mediates the mitotic senescence transition.
Andrew R J Young, Masako Narita, Manuela Ferreira, Kristina Kirschner, Mahito Sadaie, Jeremy F J Darot, Simon Tavaré, Satoko Arakawa, Shigeomi Shimizu, Fiona M Watt,[...]. Genes Dev 2009
663
5

Senescent cell clearance by the immune system: Emerging therapeutic opportunities.
Larissa G P Langhi Prata, Inna G Ovsyannikova, Tamara Tchkonia, James L Kirkland. Semin Immunol 2018
73
6

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation.
Marzia Fumagalli, Francesca Rossiello, Michela Clerici, Sara Barozzi, Davide Cittaro, Jessica M Kaplunov, Gabriele Bucci, Miryana Dobreva, Valentina Matti, Christian M Beausejour,[...]. Nat Cell Biol 2012
414
5

NAD+ metabolism governs the proinflammatory senescence-associated secretome.
Timothy Nacarelli, Lena Lau, Takeshi Fukumoto, Joseph Zundell, Nail Fatkhutdinov, Shuai Wu, Katherine M Aird, Osamu Iwasaki, Andrew V Kossenkov, David Schultz,[...]. Nat Cell Biol 2019
77
6

Impaired immune surveillance accelerates accumulation of senescent cells and aging.
Yossi Ovadya, Tomer Landsberger, Hanna Leins, Ezra Vadai, Hilah Gal, Anat Biran, Reut Yosef, Adi Sagiv, Amit Agrawal, Alon Shapira,[...]. Nat Commun 2018
119
5

Cellular senescence in naevi and immortalisation in melanoma: a role for p16?
V C Gray-Schopfer, S C Cheong, H Chong, J Chow, T Moss, Z A Abdel-Malek, R Marais, D Wynford-Thomas, D C Bennett. Br J Cancer 2006
267
5

Senescence and senotherapeutics: a new field in cancer therapy.
Vassilios Myrianthopoulos, Konstantinos Evangelou, Panagiotis V S Vasileiou, Tomer Cooks, Theodoros P Vassilakopoulos, Gerassimos A Pangalis, Myrsini Kouloukoussa, Christos Kittas, Alexandros G Georgakilas, Vassilis G Gorgoulis. Pharmacol Ther 2019
55
9

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.
Jirina Bartkova, Nousin Rezaei, Michalis Liontos, Panagiotis Karakaidos, Dimitris Kletsas, Natalia Issaeva, Leandros-Vassilios F Vassiliou, Evangelos Kolettas, Katerina Niforou, Vassilis C Zoumpourlis,[...]. Nature 2006
5

Robust, universal biomarker assay to detect senescent cells in biological specimens.
Konstantinos Evangelou, Nikolaos Lougiakis, Sophia V Rizou, Athanassios Kotsinas, Dimitris Kletsas, Daniel Muñoz-Espín, Nikolaos G Kastrinakis, Nicole Pouli, Panagiotis Marakos, Paul Townsend,[...]. Aging Cell 2017
93
5

Autophagy impairment with lysosomal and mitochondrial dysfunction is an important characteristic of oxidative stress-induced senescence.
Haoran Tai, Zhe Wang, Hui Gong, Xiaojuan Han, Jiao Zhou, Xiaobo Wang, Xiawei Wei, Yi Ding, Ning Huang, Jianqiong Qin,[...]. Autophagy 2017
109
5

TERT promoter mutations in familial and sporadic melanoma.
Susanne Horn, Adina Figl, P Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki,[...]. Science 2013
5

Molecular dissection of formation of senescence-associated heterochromatin foci.
Rugang Zhang, Wei Chen, Peter D Adams. Mol Cell Biol 2007
256
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.