A citation-based method for searching scientific literature

Harry T Orr, Huda Y Zoghbi. Annu Rev Neurosci 2007
Times Cited: 951







List of co-cited articles
1055 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



The spinocerebellar ataxias.
Henry L Paulson. J Neuroophthalmol 2009
105
4

Huntington's disease.
Francis O Walker. Lancet 2007
4

G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo.
Roberto Simone, Rubika Balendra, Thomas G Moens, Elisavet Preza, Katherine M Wilson, Amanda Heslegrave, Nathan S Woodling, Teresa Niccoli, Javier Gilbert-Jaramillo, Samir Abdelkarim,[...]. EMBO Mol Med 2018
89
4

Polyglutamine domain modulates the TBP-TFIIB interaction: implications for its normal function and neurodegeneration.
Meyer J Friedman, Anjali G Shah, Zhi-Hui Fang, Elizabeth G Ward, Stephen T Warren, Shihua Li, Xiao-Jiang Li. Nat Neurosci 2007
115
4

Neuropathological classification of Huntington's disease.
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
4

ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.
Maxime W C Rousseaux, Tyler Tschumperlin, Hsiang-Chih Lu, Elizabeth P Lackey, Vitaliy V Bondar, Ying-Wooi Wan, Qiumin Tan, Carolyn J Adamski, Jillian Friedrich, Kirk Twaroski,[...]. Neuron 2018
28
14

Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3.
Xi Chen, Tie-Shan Tang, Huiping Tu, Omar Nelson, Mark Pook, Robert Hammer, Nobuyuki Nukina, Ilya Bezprozvanny. J Neurosci 2008
148
4

Unstable expansion of CAG repeat in hereditary dentatorubral-pallidoluysian atrophy (DRPLA).
R Koide, T Ikeuchi, O Onodera, H Tanaka, S Igarashi, K Endo, H Takahashi, R Kondo, A Ishikawa, T Hayashi. Nat Genet 1994
970
4

RNA Controls PolyQ Protein Phase Transitions.
Huaiying Zhang, Shana Elbaum-Garfinkle, Erin M Langdon, Nicole Taylor, Patricia Occhipinti, Andrew A Bridges, Clifford P Brangwynne, Amy S Gladfelter. Mol Cell 2015
294
4

Polymorphic tandem repeats within gene promoters act as modifiers of gene expression and DNA methylation in humans.
Javier Quilez, Audrey Guilmatre, Paras Garg, Gareth Highnam, Melissa Gymrek, Yaniv Erlich, Ricky S Joshi, David Mittelman, Andrew J Sharp. Nucleic Acids Res 2016
46
8

Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2.
Stephen T Hansen, Pratap Meera, Thomas S Otis, Stefan M Pulst. Hum Mol Genet 2013
100
4

Protein composition of the intranuclear inclusions of FXTAS.
C K Iwahashi, D H Yasui, H-J An, C M Greco, F Tassone, K Nannen, B Babineau, C B Lebrilla, R J Hagerman, P J Hagerman. Brain 2006
239
4

RNA-binding proteins hnRNP A2/B1 and CUGBP1 suppress fragile X CGG premutation repeat-induced neurodegeneration in a Drosophila model of FXTAS.
Oyinkan A Sofola, Peng Jin, Yunlong Qin, Ranhui Duan, Huijie Liu, Maria de Haro, David L Nelson, Juan Botas. Neuron 2007
230
4

Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS.
Peter E A Ash, Kevin F Bieniek, Tania F Gendron, Thomas Caulfield, Wen-Lang Lin, Mariely Dejesus-Hernandez, Marka M van Blitterswijk, Karen Jansen-West, Joseph W Paul, Rosa Rademakers,[...]. Neuron 2013
658
4

Biomolecular condensates: organizers of cellular biochemistry.
Salman F Banani, Hyun O Lee, Anthony A Hyman, Michael K Rosen. Nat Rev Mol Cell Biol 2017
4

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.
Avinash Patel, Hyun O Lee, Louise Jawerth, Shovamayee Maharana, Marcus Jahnel, Marco Y Hein, Stoyno Stoynov, Julia Mahamid, Shambaditya Saha, Titus M Franzmann,[...]. Cell 2015
935
4

Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.
Peter Langfelder, Jeffrey P Cantle, Doxa Chatzopoulou, Nan Wang, Fuying Gao, Ismael Al-Ramahi, Xiao-Hong Lu, Eliana Marisa Ramos, Karla El-Zein, Yining Zhao,[...]. Nat Neurosci 2016
164
4

RNA-mediated neuromuscular disorders.
Laura P W Ranum, Thomas A Cooper. Annu Rev Neurosci 2006
340
4

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
4

Pathogenesis of SCA3 and implications for other polyglutamine diseases.
Hayley S McLoughlin, Lauren R Moore, Henry L Paulson. Neurobiol Dis 2020
24
16

A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical outcomes.
Marc Ciosi, Alastair Maxwell, Sarah A Cumming, Davina J Hensman Moss, Asma M Alshammari, Michael D Flower, Alexandra Durr, Blair R Leavitt, Raymund A C Roos, Peter Holmans,[...]. EBioMedicine 2019
43
9

On the wrong DNA track: Molecular mechanisms of repeat-mediated genome instability.
Alexandra N Khristich, Sergei M Mirkin. J Biol Chem 2020
33
12

Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study.
Davina J Hensman Moss, Antonio F Pardiñas, Douglas Langbehn, Kitty Lo, Blair R Leavitt, Raymund Roos, Alexandra Durr, Simon Mead, Peter Holmans, Lesley Jones,[...]. Lancet Neurol 2017
123
4

Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches.
Ricardo Mouro Pinto, Ella Dragileva, Andrew Kirby, Alejandro Lloret, Edith Lopez, Jason St Claire, Gagan B Panigrahi, Caixia Hou, Kim Holloway, Tammy Gillis,[...]. PLoS Genet 2013
102
4

RNA-mediated neurodegeneration in repeat expansion disorders.
Peter K Todd, Henry L Paulson. Ann Neurol 2010
160
4

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism.
Ashwani K Thakur, Murali Jayaraman, Rakesh Mishra, Monika Thakur, Veronique M Chellgren, In-Ja L Byeon, Dalaver H Anjum, Ravindra Kodali, Trevor P Creamer, James F Conway,[...]. Nat Struct Mol Biol 2009
296
3

Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice.
Xiaofeng Gu, Erin R Greiner, Rakesh Mishra, Ravindra Kodali, Alex Osmand, Steven Finkbeiner, Joan S Steffan, Leslie Michels Thompson, Ronald Wetzel, X William Yang. Neuron 2009
208
3

Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease.
Christian Landles, Kirupa Sathasivam, Andreas Weiss, Ben Woodman, Hilary Moffitt, Steve Finkbeiner, Banghua Sun, Juliette Gafni, Lisa M Ellerby, Yvon Trottier,[...]. J Biol Chem 2010
203
3

Huntingtin functions as a scaffold for selective macroautophagy.
Yan-Ning Rui, Zhen Xu, Bindi Patel, Zhihua Chen, Dongsheng Chen, Antonio Tito, Gabriela David, Yamin Sun, Erin F Stimming, Hugo J Bellen,[...]. Nat Cell Biol 2015
209
3

N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking.
Adam L Orr, Shihua Li, Chuan-En Wang, He Li, Jianjun Wang, Juan Rong, Xingshun Xu, Pier Giorgio Mastroberardino, J Timothy Greenamyre, Xiao-Jiang Li. J Neurosci 2008
269
3

The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis.
Erica Rockabrand, Natalia Slepko, Antonello Pantalone, Vidya N Nukala, Aleksey Kazantsev, J Lawrence Marsh, Patrick G Sullivan, Joan S Steffan, Stefano L Sensi, Leslie Michels Thompson. Hum Mol Genet 2007
184
3

SUMO modification of Huntingtin and Huntington's disease pathology.
Joan S Steffan, Namita Agrawal, Judit Pallos, Erica Rockabrand, Lloyd C Trotman, Natalia Slepko, Katalin Illes, Tamas Lukacsovich, Ya-Zhen Zhu, Elena Cattaneo,[...]. Science 2004
472
3

In Situ Architecture and Cellular Interactions of PolyQ Inclusions.
Felix J B Bäuerlein, Itika Saha, Archana Mishra, Maria Kalemanov, Antonio Martínez-Sánchez, Rüdiger Klein, Irina Dudanova, Mark S Hipp, F Ulrich Hartl, Wolfgang Baumeister,[...]. Cell 2017
115
3

The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation.
Stephen Tam, Christoph Spiess, William Auyeung, Lukasz Joachimiak, Bryan Chen, Michelle A Poirier, Judith Frydman. Nat Struct Mol Biol 2009
169
3

Ataxin-3 suppresses polyglutamine neurodegeneration in Drosophila by a ubiquitin-associated mechanism.
John M Warrick, Lance M Morabito, Julide Bilen, Beth Gordesky-Gold, Lynn Z Faust, Henry L Paulson, Nancy M Bonini. Mol Cell 2005
195
3

Machado-Joseph disease gene product is a cytoplasmic protein widely expressed in brain.
H L Paulson, S S Das, P B Crino, M K Perez, S C Patel, D Gotsdiner, K H Fischbeck, R N Pittman. Ann Neurol 1997
215
3


Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening.
Y Nagai, T Tucker, H Ren, D J Kenan, B S Henderson, J D Keene, W J Strittmatter, J R Burke. J Biol Chem 2000
140
3

Prevention of polyglutamine oligomerization and neurodegeneration by the peptide inhibitor QBP1 in Drosophila.
Yoshitaka Nagai, Nobuhiro Fujikake, Katsuhito Ohno, Hiroyuki Higashiyama, Helena A Popiel, Julia Rahadian, Masamitsu Yamaguchi, Warren J Strittmatter, James R Burke, Tatsushi Toda. Hum Mol Genet 2003
104
3

Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1.
Wing Man Chan, Ho Tsoi, Chi Chung Wu, Chi Hang Wong, Tat Cheung Cheng, Hoi Yeung Li, Kwok Fai Lau, Pang Chui Shaw, Norbert Perrimon, Ho Yin Edwin Chan. Hum Mol Genet 2011
27
11


Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006
3

Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3.
Fiona M Menzies, Jeannette Huebener, Maurizio Renna, Michael Bonin, Olaf Riess, David C Rubinsztein. Brain 2010
177
3

Global changes to the ubiquitin system in Huntington's disease.
Eric J Bennett, Thomas A Shaler, Ben Woodman, Kwon-Yul Ryu, Tatiana S Zaitseva, Christopher H Becker, Gillian P Bates, Howard Schulman, Ron R Kopito. Nature 2007
377
3


Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.
Brinda Ravikumar, Coralie Vacher, Zdenek Berger, Janet E Davies, Shouqing Luo, Lourdes G Oroz, Francesco Scaravilli, Douglas F Easton, Rainer Duden, Cahir J O'Kane,[...]. Nat Genet 2004
3

Mitochondrial abnormalities in spinal and bulbar muscular atrophy.
Srikanth Ranganathan, George G Harmison, Kristin Meyertholen, Maria Pennuto, Barrington G Burnett, Kenneth H Fischbeck. Hum Mol Genet 2009
109
3

Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy.
Isabella Palazzolo, Conor Stack, Lingling Kong, Antonio Musaro, Hiroaki Adachi, Masahisa Katsuno, Gen Sobue, J Paul Taylor, Charlotte J Sumner, Kenneth H Fischbeck,[...]. Neuron 2009
153
3

CREB-binding protein sequestration by expanded polyglutamine.
A McCampbell, J P Taylor, A A Taye, J Robitschek, M Li, J Walcott, D Merry, Y Chai, H Paulson, G Sobue,[...]. Hum Mol Genet 2000
418
3


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.