A citation-based method for searching scientific literature

Harry T Orr, Huda Y Zoghbi. Annu Rev Neurosci 2007
Times Cited: 951







List of co-cited articles
1055 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Androgen-dependent pathology demonstrates myopathic contribution to the Kennedy disease phenotype in a mouse knock-in model.
Zhigang Yu, Nahid Dadgar, Megan Albertelli, Kirsten Gruis, Cynthia Jordan, Diane M Robins, Andrew P Lieberman. J Clin Invest 2006
123
3

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.
E Scherzinger, R Lurz, M Turmaine, L Mangiarini, B Hollenbach, R Hasenbank, G P Bates, S W Davies, H Lehrach, E E Wanker. Cell 1997
978
3

Protein aggregates in Huntington's disease.
Montserrat Arrasate, Steven Finkbeiner. Exp Neurol 2012
174
3

Molecular chaperone functions in protein folding and proteostasis.
Yujin E Kim, Mark S Hipp, Andreas Bracher, Manajit Hayer-Hartl, F Ulrich Hartl. Annu Rev Biochem 2013
746
3

Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation.
Zheng Ying, Hongfeng Wang, Huadong Fan, Xiaodong Zhu, Jiawei Zhou, Erkang Fei, Guanghui Wang. Hum Mol Genet 2009
85
3


CHIP protects from the neurotoxicity of expanded and wild-type ataxin-1 and promotes their ubiquitination and degradation.
Ismael Al-Ramahi, Yung C Lam, Hung-Kai Chen, Beatrice de Gouyon, Minghang Zhang, Alma M Pérez, Joana Branco, Maria de Haro, Cam Patterson, Huda Y Zoghbi,[...]. J Biol Chem 2006
136
3

Polyglutamine protein aggregates are dynamic.
Soojin Kim, Ellen A A Nollen, Kazunori Kitagawa, Vytautas P Bindokas, Richard I Morimoto. Nat Cell Biol 2002
224
3

Prediction of the age at onset in spinocerebellar ataxia type 1, 2, 3 and 6.
Sophie Tezenas du Montcel, Alexandra Durr, Maria Rakowicz, Lorenzo Nanetti, Perrine Charles, Anna Sulek, Caterina Mariotti, Rafal Rola, Ludger Schols, Peter Bauer,[...]. J Med Genet 2014
36
8


Promoter-bound trinucleotide repeat mRNA drives epigenetic silencing in fragile X syndrome.
Dilek Colak, Nikica Zaninovic, Michael S Cohen, Zev Rosenwaks, Wang-Yong Yang, Jeannine Gerhardt, Matthew D Disney, Samie R Jaffrey. Science 2014
173
3

Characterization of DNA G-quadruplex species forming from C9ORF72 G4C2-expanded repeats associated with amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
Primož Šket, Jure Pohleven, Anja Kovanda, Maja Štalekar, Vera Župunski, Matja Zalar, Janez Plavec, Boris Rogelj. Neurobiol Aging 2015
48
6

Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy.
J W Miller, C R Urbinati, P Teng-Umnuay, M G Stenberg, B J Byrne, C A Thornton, M S Swanson. EMBO J 2000
615
3

The C9ORF72 GGGGCC expansion forms RNA G-quadruplex inclusions and sequesters hnRNP H to disrupt splicing in ALS brains.
Erin G Conlon, Lei Lu, Aarti Sharma, Takashi Yamazaki, Timothy Tang, Neil A Shneider, James L Manley. Elife 2016
127
3

C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes.
Pietro Fratta, Sarah Mizielinska, Andrew J Nicoll, Mire Zloh, Elizabeth M C Fisher, Gary Parkinson, Adrian M Isaacs. Sci Rep 2012
201
3

The disease-associated r(GGGGCC)n repeat from the C9orf72 gene forms tract length-dependent uni- and multimolecular RNA G-quadruplex structures.
Kaalak Reddy, Bita Zamiri, Sabrina Y R Stanley, Robert B Macgregor, Christopher E Pearson. J Biol Chem 2013
204
3

A small molecule that targets r(CGG)(exp) and improves defects in fragile X-associated tremor ataxia syndrome.
Matthew D Disney, Biao Liu, Wang-Yong Yang, Chantal Sellier, Tuan Tran, Nicolas Charlet-Berguerand, Jessica L Childs-Disney. ACS Chem Biol 2012
67
4

Structural diversity of triplet repeat RNAs.
Krzysztof Sobczak, Gracjan Michlewski, Mateusz de Mezer, Elzbieta Kierzek, Jacek Krol, Marta Olejniczak, Ryszard Kierzek, Wlodzimierz J Krzyzosiak. J Biol Chem 2010
82
3

Rationally designed small molecules targeting toxic CAG repeat RNA that causes Huntington's disease (HD) and spinocerebellar ataxia (SCAs).
Eshan Khan, Soumen Biswas, Subodh Kumar Mishra, Ribhav Mishra, Sampak Samanta, Amit Mishra, Arpita Tawani, Amit Kumar. Biochimie 2019
9
33

Myricetin Reduces Toxic Level of CAG Repeats RNA in Huntington's Disease (HD) and Spino Cerebellar Ataxia (SCAs).
Eshan Khan, Arpita Tawani, Subodh Kumar Mishra, Arun Kumar Verma, Arun Upadhyay, Mohit Kumar, Rajat Sandhir, Amit Mishra, Amit Kumar. ACS Chem Biol 2018
15
20

Chemical correction of pre-mRNA splicing defects associated with sequestration of muscleblind-like 1 protein by expanded r(CAG)-containing transcripts.
Amit Kumar, Raman Parkesh, Lukasz J Sznajder, Jessica L Childs-Disney, Krzysztof Sobczak, Matthew D Disney. ACS Chem Biol 2012
58
5

Expanded clinical phenotype of women with the FMR1 premutation.
Sarah M Coffey, Kylee Cook, Nicole Tartaglia, Flora Tassone, Danh V Nguyen, Ruiqin Pan, Hannah E Bronsky, Jennifer Yuhas, Mariya Borodyanskaya, Jim Grigsby,[...]. Am J Med Genet A 2008
210
3

Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome.
Chantal Sellier, Ronald A M Buijsen, Fang He, Sam Natla, Laura Jung, Philippe Tropel, Angeline Gaucherot, Hugues Jacobs, Hamid Meziane, Alexandre Vincent,[...]. Neuron 2017
102
3

Fragile X-associated tremor/ataxia syndrome.
Paul J Hagerman, Randi J Hagerman. Ann N Y Acad Sci 2015
86
3

Regional rescue of spinocerebellar ataxia type 1 phenotypes by 14-3-3epsilon haploinsufficiency in mice underscores complex pathogenicity in neurodegeneration.
Paymaan Jafar-Nejad, Christopher S Ward, Ronald Richman, Harry T Orr, Huda Y Zoghbi. Proc Natl Acad Sci U S A 2011
46
6

DNA repair pathways underlie a common genetic mechanism modulating onset in polyglutamine diseases.
Conceição Bettencourt, Davina Hensman-Moss, Michael Flower, Sarah Wiethoff, Alexis Brice, Cyril Goizet, Giovanni Stevanin, Georgios Koutsis, Georgia Karadima, Marios Panas,[...]. Ann Neurol 2016
103
3

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.
C J Cummings, M A Mancini, B Antalffy, D B DeFranco, H T Orr, H Y Zoghbi. Nat Genet 1998
673
3

Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.
I A Klement, P J Skinner, M D Kaytor, H Yi, S M Hersch, H B Clark, H Y Zoghbi, H T Orr. Cell 1998
792
3

Toward RNAi therapy for the polyglutamine disease Machado-Joseph disease.
Maria do Carmo Costa, Katiuska Luna-Cancalon, Svetlana Fischer, Naila S Ashraf, Michelle Ouyang, Rahil M Dharia, Lucas Martin-Fishman, Yemen Yang, Vikram G Shakkottai, Beverly L Davidson,[...]. Mol Ther 2013
63
4

Sodium butyrate ameliorates histone hypoacetylation and neurodegenerative phenotypes in a mouse model for DRPLA.
Mingyao Ying, Rener Xu, Xiaohui Wu, Huaxing Zhu, Yuan Zhuang, Min Han, Tian Xu. J Biol Chem 2006
70
4


Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial.
Masahisa Katsuno, Haruhiko Banno, Keisuke Suzuki, Yu Takeuchi, Motoshi Kawashima, Ichiro Yabe, Hidenao Sasaki, Masashi Aoki, Mitsuya Morita, Imaharu Nakano,[...]. Lancet Neurol 2010
120
3

Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia.
Sunil Sahdeo, Brian D Scott, Marissa Z McMackin, Mittal Jasoliya, Brandon Brown, Heike Wulff, Susan L Perlman, Mark A Pook, Gino A Cortopassi. Hum Mol Genet 2014
42
7


Precise small-molecule recognition of a toxic CUG RNA repeat expansion.
Suzanne G Rzuczek, Lesley A Colgan, Yoshio Nakai, Michael D Cameron, Denis Furling, Ryohei Yasuda, Matthew D Disney. Nat Chem Biol 2017
98
3

Epigenetic therapy for Friedreich ataxia.
Elisabetta Soragni, Wenyan Miao, Marco Iudicello, David Jacoby, Stefania De Mercanti, Marinella Clerico, Filomena Longo, Antonio Piga, Sherman Ku, Erica Campau,[...]. Ann Neurol 2014
83
3

Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models.
Dagmar E Ehrnhoefer, Martin Duennwald, Phoebe Markovic, Jennifer L Wacker, Sabine Engemann, Margaret Roark, Justin Legleiter, J Lawrence Marsh, Leslie M Thompson, Susan Lindquist,[...]. Hum Mol Genet 2006
255
3



An information-rich CGG repeat primed PCR that detects the full range of fragile X expanded alleles and minimizes the need for southern blot analysis.
Liangjing Chen, Andrew Hadd, Sachin Sah, Stela Filipovic-Sadic, Julie Krosting, Edward Sekinger, Ruiqin Pan, Paul J Hagerman, Timothy T Stenzel, Flora Tassone,[...]. J Mol Diagn 2010
115
3


The balancing act of DNA repeat expansions.
Jane C Kim, Sergei M Mirkin. Curr Opin Genet Dev 2013
72
4

Evidence of cis-acting factors in replication-mediated trinucleotide repeat instability in primate cells.
John D Cleary, Kerrie Nichol, Yuh-Hwa Wang, Christopher E Pearson. Nat Genet 2002
147
3

Spt4 is selectively required for transcription of extended trinucleotide repeats.
Chia-Rung Liu, Chuang-Rung Chang, Yijuang Chern, Tzu-Han Wang, Wen-Chieh Hsieh, Wen-Chuan Shen, Chi-Yuan Chang, I-Chieh Chu, Ning Deng, Stanley N Cohen,[...]. Cell 2012
61
4

Recovery from polyglutamine-induced neurodegeneration in conditional SCA1 transgenic mice.
Tao Zu, Lisa A Duvick, Michael D Kaytor, Michael S Berlinger, Huda Y Zoghbi, H Brent Clark, Harry T Orr. J Neurosci 2004
184
3


R loops stimulate genetic instability of CTG.CAG repeats.
Yunfu Lin, Sharon Y R Dent, John H Wilson, Robert D Wells, Marek Napierala. Proc Natl Acad Sci U S A 2010
123
3

Ubiquitin-binding site 2 of ataxin-3 prevents its proteasomal degradation by interacting with Rad23.
Jessica R Blount, Wei-Ling Tsou, Gorica Ristic, Aaron A Burr, Michelle Ouyang, Holland Galante, K Matthew Scaglione, Sokol V Todi. Nat Commun 2014
40
7

Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic mice.
Clévio Nóbrega, Isabel Nascimento-Ferreira, Isabel Onofre, David Albuquerque, Hirokazu Hirai, Nicole Déglon, Luís Pereira de Almeida. PLoS One 2013
77
3

Polyglutamine length-dependent toxicity from α1ACT in Drosophila models of spinocerebellar ataxia type 6.
Wei-Ling Tsou, Sultan H Qiblawi, Ryan R Hosking, Christopher M Gomez, Sokol V Todi. Biol Open 2016
11
27


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.