A citation-based method for searching scientific literature

A Phillip West, William Khoury-Hanold, Matthew Staron, Michal C Tal, Cristiana M Pineda, Sabine M Lang, Megan Bestwick, Brett A Duguay, Nuno Raimundo, Donna A MacDuff, Susan M Kaech, James R Smiley, Robert E Means, Akiko Iwasaki, Gerald S Shadel. Nature 2015
Times Cited: 789







List of co-cited articles
1145 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Mitochondrial DNA induces inflammation and increases TLR9/NF-κB expression in lung tissue.
Jian-Zheng Zhang, Zhi Liu, Jia Liu, Ji-Xin Ren, Tian-Sheng Sun. Int J Mol Med 2014
141
8

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation.
Zhenyu Zhong, Shuang Liang, Elsa Sanchez-Lopez, Feng He, Shabnam Shalapour, Xue-Jia Lin, Jerry Wong, Siyuan Ding, Ekihiro Seki, Bernd Schnabl,[...]. Nature 2018
382
8

Mitochondrial permeability transition triggers the release of mtDNA fragments.
M Patrushev, V Kasymov, V Patrusheva, T Ushakova, V Gogvadze, A Gaziev. Cell Mol Life Sci 2004
82
9

Nuclear sensing of breaks in mitochondrial DNA enhances immune surveillance.
Marco Tigano, Danielle C Vargas, Samuel Tremblay-Belzile, Yi Fu, Agnel Sfeir. Nature 2021
53
15

Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA.
Katherine C Barnett, Julia M Coronas-Serna, Wen Zhou, Michael J Ernandes, Anh Cao, Philip J Kranzusch, Jonathan C Kagan. Cell 2019
96
8

The molecular basis of tight nuclear tethering and inactivation of cGAS.
Baoyu Zhao, Pengbiao Xu, Chesley M Rowlett, Tao Jing, Omkar Shinde, Yuanjiu Lei, A Phillip West, Wenshe Ray Liu, Pingwei Li. Nature 2020
70
11

DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway.
Juli Bai, Christopher Cervantes, Juan Liu, Sijia He, Haiyan Zhou, Bilin Zhang, Huan Cai, Dongqing Yin, Derong Hu, Zhi Li,[...]. Proc Natl Acad Sci U S A 2017
93
8

Sequence and organization of the human mitochondrial genome.
S Anderson, A T Bankier, B G Barrell, M H de Bruijn, A R Coulson, J Drouin, I C Eperon, D P Nierlich, B A Roe, F Sanger,[...]. Nature 1981
8

Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.
Guijun Shang, Conggang Zhang, Zhijian J Chen, Xiao-Chen Bai, Xuewu Zhang. Nature 2019
179
8

Structural basis of STING binding with and phosphorylation by TBK1.
Conggang Zhang, Guijun Shang, Xiang Gui, Xuewu Zhang, Xiao-Chen Bai, Zhijian J Chen. Nature 2019
222
8

cGAS in action: Expanding roles in immunity and inflammation.
Andrea Ablasser, Zhijian J Chen. Science 2019
271
7

STING: infection, inflammation and cancer.
Glen N Barber. Nat Rev Immunol 2015
569
7

Cytosolic RNA:DNA hybrids activate the cGAS-STING axis.
Arun K Mankan, Tobias Schmidt, Dhruv Chauhan, Marion Goldeck, Klara Höning, Moritz Gaidt, Andrew V Kubarenko, Liudmila Andreeva, Karl-Peter Hopfner, Veit Hornung. EMBO J 2014
177
7


DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity.
Anetta Härtlova, Saskia F Erttmann, Faizal Am Raffi, Anja M Schmalz, Ulrike Resch, Sharath Anugula, Stefan Lienenklaus, Lisa M Nilsson, Andrea Kröger, Jonas A Nilsson,[...]. Immunity 2015
403
7

Apoptotic Caspases Suppress Type I Interferon Production via the Cleavage of cGAS, MAVS, and IRF3.
Xiaohan Ning, Yutao Wang, Miao Jing, Mengyin Sha, Mengze Lv, Pengfei Gao, Rui Zhang, Xiaojun Huang, Ji-Ming Feng, Zhengfan Jiang. Mol Cell 2019
96
7

The cGAS-cGAMP-STING pathway of cytosolic DNA sensing and signaling.
Xin Cai, Yu-Hsin Chiu, Zhijian J Chen. Mol Cell 2014
525
7

Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING.
Xu Zhang, Heping Shi, Jiaxi Wu, Xuewu Zhang, Lijun Sun, Chuo Chen, Zhijian J Chen. Mol Cell 2013
538
7

The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING.
Elie J Diner, Dara L Burdette, Stephen C Wilson, Kathryn M Monroe, Colleen A Kellenberger, Mamoru Hyodo, Yoshihiro Hayakawa, Ming C Hammond, Russell E Vance. Cell Rep 2013
437
7

Structure of human cGAS reveals a conserved family of second-messenger enzymes in innate immunity.
Philip J Kranzusch, Amy Si-Ying Lee, James M Berger, Jennifer A Doudna. Cell Rep 2013
211
7

Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation.
Shankar S Iyer, Qiong He, John R Janczy, Eric I Elliott, Zhenyu Zhong, Alicia K Olivier, Jeffrey J Sadler, Vickie Knepper-Adrian, Renzhi Han, Liang Qiao,[...]. Immunity 2013
492
7

Mitochondria in innate immune responses.
A Phillip West, Gerald S Shadel, Sankar Ghosh. Nat Rev Immunol 2011
763
7

Structure of the Human cGAS-DNA Complex Reveals Enhanced Control of Immune Surveillance.
Wen Zhou, Aaron T Whiteley, Carina C de Oliveira Mann, Benjamin R Morehouse, Radosław P Nowak, Eric S Fischer, Nathanael S Gray, John J Mekalanos, Philip J Kranzusch. Cell 2018
125
7

Chromatin-bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death.
Hui Jiang, Xiaoyu Xue, Swarupa Panda, Ajinkya Kawale, Richard M Hooy, Fengshan Liang, Jungsan Sohn, Patrick Sung, Nelson O Gekara. EMBO J 2019
97
7

TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells.
Katherine R Balka, Cynthia Louis, Tahnee L Saunders, Amber M Smith, Dale J Calleja, Damian B D'Silva, Fiona Moghaddas, Maximilien Tailler, Kate E Lawlor, Yifan Zhan,[...]. Cell Rep 2020
75
9

Structural mechanism of cGAS inhibition by the nucleosome.
Ganesh R Pathare, Alexiane Decout, Selene Glück, Simone Cavadini, Kristina Makasheva, Ruud Hovius, Georg Kempf, Joscha Weiss, Zuzanna Kozicka, Baptiste Guey,[...]. Nature 2020
80
8

Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity.
Jiang Dai, Yi-Jiao Huang, Xinhua He, Ming Zhao, Xinzheng Wang, Zhao-Shan Liu, Wen Xue, Hong Cai, Xiao-Yan Zhan, Shao-Yi Huang,[...]. Cell 2019
113
7

The cGAS-STING pathway as a therapeutic target in inflammatory diseases.
Alexiane Decout, Jason D Katz, Shankar Venkatraman, Andrea Ablasser. Nat Rev Immunol 2021
94
7

Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage.
Gillian Dunphy, Sinéad M Flannery, Jessica F Almine, Dympna J Connolly, Christina Paulus, Kasper L Jønsson, Martin R Jakobsen, Michael M Nevels, Andrew G Bowie, Leonie Unterholzner. Mol Cell 2018
212
7

Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury.
Hiroshi Maekawa, Tsuyoshi Inoue, Haruki Ouchi, Tzu-Ming Jao, Reiko Inoue, Hiroshi Nishi, Rie Fujii, Fumiyoshi Ishidate, Tetsuhiro Tanaka, Yosuke Tanaka,[...]. Cell Rep 2019
108
7

Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases.
Daxing Gao, Tuo Li, Xiao-Dong Li, Xiang Chen, Quan-Zhen Li, Mary Wight-Carter, Zhijian J Chen. Proc Natl Acad Sci U S A 2015
335
7

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation.
Bo Zhong, Yan Yang, Shu Li, Yan-Yi Wang, Ying Li, Feici Diao, Caoqi Lei, Xiao He, Lu Zhang, Po Tien,[...]. Immunity 2008
903
6

The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3.
Moritz M Gaidt, Thomas S Ebert, Dhruv Chauhan, Katharina Ramshorn, Francesca Pinci, Sarah Zuber, Fionan O'Duill, Jonathan L Schmid-Burgk, Florian Hoss, Raymund Buhmann,[...]. Cell 2017
226
6

MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response.
Fajian Hou, Lijun Sun, Hui Zheng, Brian Skaug, Qiu-Xing Jiang, Zhijian J Chen. Cell 2011
784
6

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction.
Taro Kawai, Ken Takahashi, Shintaro Sato, Cevayir Coban, Himanshu Kumar, Hiroki Kato, Ken J Ishii, Osamu Takeuchi, Shizuo Akira. Nat Immunol 2005
6

The Roles of Mitochondrial Damage-Associated Molecular Patterns in Diseases.
Kiichi Nakahira, Shu Hisata, Augustine M K Choi. Antioxid Redox Signal 2015
133
6

STING-mediated inflammation in Kupffer cells contributes to progression of nonalcoholic steatohepatitis.
Yongsheng Yu, Yu Liu, Weishuai An, Jingwen Song, Yuefan Zhang, Xianxian Zhao. J Clin Invest 2019
117
6

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
6

cGAS is activated by DNA in a length-dependent manner.
Stefanie Luecke, Andreas Holleufer, Maria H Christensen, Kasper L Jønsson, Gerardo A Boni, Lambert K Sørensen, Mogens Johannsen, Martin R Jakobsen, Rune Hartmann, Søren R Paludan. EMBO Rep 2017
119
6

Structural basis of nucleosome-dependent cGAS inhibition.
Joshua A Boyer, Cathy J Spangler, Joshua D Strauss, Andrew P Cesmat, Pengda Liu, Robert K McGinty, Qi Zhang. Science 2020
73
8

Structural basis for the inhibition of cGAS by nucleosomes.
Tomoya Kujirai, Christian Zierhut, Yoshimasa Takizawa, Ryan Kim, Lumi Negishi, Nobuki Uruma, Seiya Hirai, Hironori Funabiki, Hitoshi Kurumizaka. Science 2020
77
7

Structural basis for sequestration and autoinhibition of cGAS by chromatin.
Sebastian Michalski, Carina C de Oliveira Mann, Che A Stafford, Gregor Witte, Joseph Bartho, Katja Lammens, Veit Hornung, Karl-Peter Hopfner. Nature 2020
72
8

Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response.
Tatsuya Saitoh, Naonobu Fujita, Takuya Hayashi, Keigo Takahara, Takashi Satoh, Hanna Lee, Kohichi Matsunaga, Shun Kageyama, Hiroko Omori, Takeshi Noda,[...]. Proc Natl Acad Sci U S A 2009
519
6

Premature ageing in mice expressing defective mitochondrial DNA polymerase.
Aleksandra Trifunovic, Anna Wredenberg, Maria Falkenberg, Johannes N Spelbrink, Anja T Rovio, Carl E Bruder, Mohammad Bohlooly-Y, Sebastian Gidlöf, Anders Oldfors, Rolf Wibom,[...]. Nature 2004
6

Expression of STING Is Increased in Liver Tissues From Patients With NAFLD and Promotes Macrophage-Mediated Hepatic Inflammation and Fibrosis in Mice.
Xianjun Luo, Honggui Li, Linqiang Ma, Jing Zhou, Xin Guo, Shih-Lung Woo, Ya Pei, Linda R Knight, Michael Deveau, Yanming Chen,[...]. Gastroenterology 2018
121
6

The E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response.
Qiang Wang, Liyuan Huang, Ze Hong, Zhongshi Lv, Zhaomin Mao, Yijun Tang, Xiufang Kong, Senlin Li, Ye Cui, Heng Liu,[...]. PLoS Pathog 2017
75
8

Activation of the STING-IRF3 pathway promotes hepatocyte inflammation, apoptosis and induces metabolic disorders in nonalcoholic fatty liver disease.
J T Qiao, C Cui, L Qing, L S Wang, T Y He, F Yan, F Q Liu, Y H Shen, X G Hou, L Chen. Metabolism 2018
80
7


Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects.
Xiao-Dong Li, Jiaxi Wu, Daxing Gao, Hua Wang, Lijun Sun, Zhijian J Chen. Science 2013
628
5

Sumoylation Promotes the Stability of the DNA Sensor cGAS and the Adaptor STING to Regulate the Kinetics of Response to DNA Virus.
Ming-Ming Hu, Qing Yang, Xue-Qin Xie, Chen-Yang Liao, Heng Lin, Tian-Tian Liu, Lei Yin, Hong-Bing Shu. Immunity 2016
178
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.