A citation-based method for searching scientific literature

Owen M Peters, Gabriela Toro Cabrera, Helene Tran, Tania F Gendron, Jeanne E McKeon, Jake Metterville, Alexandra Weiss, Nicholas Wightman, Johnny Salameh, Juyhun Kim, Huaming Sun, Kevin B Boylan, Dennis Dickson, Zack Kennedy, Ziqiang Lin, Yong-Jie Zhang, Lillian Daughrity, Chris Jung, Fen-Biao Gao, Peter C Sapp, H Robert Horvitz, Daryl A Bosco, Solange P Brown, Pieter de Jong, Leonard Petrucelli, Chris Mueller, Robert H Brown. Neuron 2015
Times Cited: 159







List of co-cited articles
1674 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons.
Rodrigo Lopez-Gonzalez, Yubing Lu, Tania F Gendron, Anna Karydas, Helene Tran, Dejun Yang, Leonard Petrucelli, Bruce L Miller, Sandra Almeida, Fen-Biao Gao. Neuron 2016
168
21

Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis.
Yong-Jie Zhang, Tania F Gendron, Mark T W Ebbert, Aliesha D O'Raw, Mei Yue, Karen Jansen-West, Xu Zhang, Mercedes Prudencio, Jeannie Chew, Casey N Cook,[...]. Nat Med 2018
119
21

Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons.
Sandra Almeida, Eduardo Gascon, Hélène Tran, Hsin Jung Chou, Tania F Gendron, Steven Degroot, Andrew R Tapper, Chantal Sellier, Nicolas Charlet-Berguerand, Anna Karydas,[...]. Acta Neuropathol 2013
232
20

Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations.
Ian R Mackenzie, Thomas Arzberger, Elisabeth Kremmer, Dirk Troost, Stefan Lorenzl, Kohji Mori, Shih-Ming Weng, Christian Haass, Hans A Kretzschmar, Dieter Edbauer,[...]. Acta Neuropathol 2013
226
20

Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity.
Zhouteng Tao, Hongfeng Wang, Qin Xia, Ke Li, Kai Li, Xiaogang Jiang, Guoqiang Xu, Guanghui Wang, Zheng Ying. Hum Mol Genet 2015
143
20

C9orf72 binds SMCR8, localizes to lysosomes, and regulates mTORC1 signaling.
Joseph Amick, Agnes Roczniak-Ferguson, Shawn M Ferguson. Mol Biol Cell 2016
102
20

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.
D R Rosen, T Siddique, D Patterson, D A Figlewicz, P Sapp, A Hentati, D Donaldson, J Goto, J P O'Regan, H X Deng. Nature 1993
19

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6.
Caroline Vance, Boris Rogelj, Tibor Hortobágyi, Kurt J De Vos, Agnes Lumi Nishimura, Jemeen Sreedharan, Xun Hu, Bradley Smith, Deborah Ruddy, Paul Wright,[...]. Science 2009
19

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis.
Jemeen Sreedharan, Ian P Blair, Vineeta B Tripathi, Xun Hu, Caroline Vance, Boris Rogelj, Steven Ackerley, Jennifer C Durnall, Kelly L Williams, Emanuele Buratti,[...]. Science 2008
19

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation.
M E Gurney, H Pu, A Y Chiu, M C Dal Canto, C Y Polchow, D D Alexander, J Caliendo, A Hentati, Y W Kwon, H X Deng. Science 1994
19

Sense-encoded poly-GR dipeptide repeat proteins correlate to neurodegeneration and uniquely co-localize with TDP-43 in dendrites of repeat-expanded C9orf72 amyotrophic lateral sclerosis.
Shahram Saberi, Jennifer E Stauffer, Jie Jiang, Sandra Diaz Garcia, Amy E Taylor, Derek Schulte, Takuya Ohkubo, Cheyenne L Schloffman, Marcus Maldonado, Michael Baughn,[...]. Acta Neuropathol 2018
82
23

Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis.
Tania F Gendron, Jeannie Chew, Jeannette N Stankowski, Lindsey R Hayes, Yong-Jie Zhang, Mercedes Prudencio, Yari Carlomagno, Lillian M Daughrity, Karen Jansen-West, Emilie A Perkerson,[...]. Sci Transl Med 2017
100
19

A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism.
Bart Swinnen, Andre Bento-Abreu, Tania F Gendron, Steven Boeynaems, Elke Bogaert, Rik Nuyts, Mieke Timmers, Wendy Scheveneels, Nicole Hersmus, Jiou Wang,[...]. Acta Neuropathol 2018
56
33

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking.
Manal A Farg, Vinod Sundaramoorthy, Jessica M Sultana, Shu Yang, Rachel A K Atkinson, Vita Levina, Mark A Halloran, Paul A Gleeson, Ian P Blair, Kai Y Soo,[...]. Hum Mol Genet 2014
286
18

Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood.
Veronique V Belzil, Peter O Bauer, Mercedes Prudencio, Tania F Gendron, Caroline T Stetler, Irene K Yan, Luc Pregent, Lillian Daughrity, Matthew C Baker, Rosa Rademakers,[...]. Acta Neuropathol 2013
185
18

The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy.
Christopher P Webster, Emma F Smith, Claudia S Bauer, Annekathrin Moller, Guillaume M Hautbergue, Laura Ferraiuolo, Monika A Myszczynska, Adrian Higginbottom, Matthew J Walsh, Alexander J Whitworth,[...]. EMBO J 2016
208
18

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS.
Andrew C Elden, Hyung-Jun Kim, Michael P Hart, Alice S Chen-Plotkin, Brian S Johnson, Xiaodong Fang, Maria Armakola, Felix Geser, Robert Greene, Min Min Lu,[...]. Nature 2010
758
18

Discovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALS.
Zhaoming Su, Yongjie Zhang, Tania F Gendron, Peter O Bauer, Jeannie Chew, Wang-Yong Yang, Erik Fostvedt, Karen Jansen-West, Veronique V Belzil, Pamela Desaro,[...]. Neuron 2014
212
18

Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics.
Steven Boeynaems, Elke Bogaert, Denes Kovacs, Albert Konijnenberg, Evy Timmerman, Alex Volkov, Mainak Guharoy, Mathias De Decker, Tom Jaspers, Veronica H Ryan,[...]. Mol Cell 2017
233
18

Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling.
Janet Ugolino, Yon Ju Ji, Karen Conchina, Justin Chu, Raja Sekhar Nirujogi, Akhilesh Pandey, Nathan R Brady, Anne Hamacher-Brady, Jiou Wang. PLoS Genet 2016
100
18

C9orf72-mediated ALS and FTD: multiple pathways to disease.
Rubika Balendra, Adrian M Isaacs. Nat Rev Neurol 2018
197
18

Novel clinical associations with specific C9ORF72 transcripts in patients with repeat expansions in C9ORF72.
Marka van Blitterswijk, Tania F Gendron, Matthew C Baker, Mariely DeJesus-Hernandez, NiCole A Finch, Patricia H Brown, Lillian M Daughrity, Melissa E Murray, Michael G Heckman, Jie Jiang,[...]. Acta Neuropathol 2015
73
23

Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy.
Johnathan Cooper-Knock, Adrian Higginbottom, Matthew J Stopford, J Robin Highley, Paul G Ince, Stephen B Wharton, Stuart Pickering-Brown, Janine Kirby, Guillaume M Hautbergue, Pamela J Shaw. Acta Neuropathol 2015
100
17

Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS.
Mercedes Prudencio, Veronique V Belzil, Ranjan Batra, Christian A Ross, Tania F Gendron, Luc J Pregent, Melissa E Murray, Karen K Overstreet, Amelia E Piazza-Johnston, Pamela Desaro,[...]. Nat Neurosci 2015
201
17

The product of C9orf72, a gene strongly implicated in neurodegeneration, is structurally related to DENN Rab-GEFs.
Timothy P Levine, Rachel D Daniels, Alberto T Gatta, Louise H Wong, Matthew J Hayes. Bioinformatics 2013
242
16

Deletion of C9ORF72 results in motor neuron degeneration and stress sensitivity in C. elegans.
Martine Therrien, Guy A Rouleau, Patrick A Dion, J Alex Parker. PLoS One 2013
125
16

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Tetsuaki Arai, Masato Hasegawa, Haruhiko Akiyama, Kenji Ikeda, Takashi Nonaka, Hiroshi Mori, David Mann, Kuniaki Tsuchiya, Mari Yoshida, Yoshio Hashizume,[...]. Biochem Biophys Res Commun 2006
16

FTD/ALS-associated poly(GR) protein impairs the Notch pathway and is recruited by poly(GA) into cytoplasmic inclusions.
Dejun Yang, Abbas Abdallah, Zhaodong Li, Yubing Lu, Sandra Almeida, Fen-Biao Gao. Acta Neuropathol 2015
86
18

Sense and antisense RNA are not toxic in Drosophila models of C9orf72-associated ALS/FTD.
Thomas G Moens, Sarah Mizielinska, Teresa Niccoli, Jamie S Mitchell, Annora Thoeng, Charlotte E Ridler, Sebastian Grönke, Jacqueline Esser, Amanda Heslegrave, Henrik Zetterberg,[...]. Acta Neuropathol 2018
36
44

Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers.
Yi Lin, Eiichiro Mori, Masato Kato, Siheng Xiang, Leeju Wu, Ilmin Kwon, Steven L McKnight. Cell 2016
186
15

The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease.
Aaron R Haeusler, Christopher J Donnelly, Jeffrey D Rothstein. Nat Rev Neurosci 2016
114
15

The disease-associated r(GGGGCC)n repeat from the C9orf72 gene forms tract length-dependent uni- and multimolecular RNA G-quadruplex structures.
Kaalak Reddy, Bita Zamiri, Sabrina Y R Stanley, Robert B Macgregor, Christopher E Pearson. J Biol Chem 2013
208
15

Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts.
Nicholas J Kramer, Yari Carlomagno, Yong-Jie Zhang, Sandra Almeida, Casey N Cook, Tania F Gendron, Mercedes Prudencio, Marka Van Blitterswijk, Veronique Belzil, Julien Couthouis,[...]. Science 2016
78
19

Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity.
Yong-Jie Zhang, Lin Guo, Patrick K Gonzales, Tania F Gendron, Yanwei Wu, Karen Jansen-West, Aliesha D O'Raw, Sarah R Pickles, Mercedes Prudencio, Yari Carlomagno,[...]. Science 2019
82
18

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS.
Hong Joo Kim, Nam Chul Kim, Yong-Dong Wang, Emily A Scarborough, Jennifer Moore, Zamia Diaz, Kyle S MacLea, Brian Freibaum, Songqing Li, Amandine Molliex,[...]. Nature 2013
848
14

Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing.
Martin H Schludi, Stephanie May, Friedrich A Grässer, Kristin Rentzsch, Elisabeth Kremmer, Clemens Küpper, Thomas Klopstock, Thomas Arzberger, Dieter Edbauer. Acta Neuropathol 2015
117
14

In-depth clinico-pathological examination of RNA foci in a large cohort of C9ORF72 expansion carriers.
Mariely DeJesus-Hernandez, NiCole A Finch, Xue Wang, Tania F Gendron, Kevin F Bieniek, Michael G Heckman, Aliaksei Vasilevich, Melissa E Murray, Linda Rousseau, Rachael Weesner,[...]. Acta Neuropathol 2017
49
28

State of play in amyotrophic lateral sclerosis genetics.
Alan E Renton, Adriano Chiò, Bryan J Traynor. Nat Neurosci 2014
878
14

Toxic PRn poly-dipeptides encoded by the C9orf72 repeat expansion block nuclear import and export.
Kevin Y Shi, Eiichiro Mori, Zehra F Nizami, Yi Lin, Masato Kato, Siheng Xiang, Leeju C Wu, Ming Ding, Yonghao Yu, Joseph G Gall,[...]. Proc Natl Acad Sci U S A 2017
120
14

Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation.
Kohsuke Kanekura, Takuya Yagi, Alexander J Cammack, Jana Mahadevan, Masahiko Kuroda, Matthew B Harms, Timothy M Miller, Fumihiko Urano. Hum Mol Genet 2016
82
17

C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia.
Yoshitsugu Aoki, Raquel Manzano, Yi Lee, Ruxandra Dafinca, Misako Aoki, Andrew G L Douglas, Miguel A Varela, Chaitra Sathyaprakash, Jakub Scaber, Paola Barbagallo,[...]. Brain 2017
82
17

Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration.
Yu Ohki, Andrea Wenninger-Weinzierl, Alexander Hruscha, Kazuhide Asakawa, Koichi Kawakami, Christian Haass, Dieter Edbauer, Bettina Schmid. Mol Neurodegener 2017
38
36

Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers.
Petra Frick, Chantal Sellier, Ian R A Mackenzie, Chieh-Yu Cheng, Julie Tahraoui-Bories, Cecile Martinat, R Jeroen Pasterkamp, Johannes Prudlo, Dieter Edbauer, Mustapha Oulad-Abdelghani,[...]. Acta Neuropathol Commun 2018
50
28

p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS.
Safa Al-Sarraj, Andrew King, Claire Troakes, Bradley Smith, Satomi Maekawa, Istvan Bodi, Boris Rogelj, Ammar Al-Chalabi, Tibor Hortobágyi, Christopher E Shaw. Acta Neuropathol 2011
345
13

A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy.
Mei Yang, Chen Liang, Kunchithapadam Swaminathan, Stephanie Herrlinger, Fan Lai, Ramin Shiekhattar, Jian-Fu Chen. Sci Adv 2016
132
13

Mutations of optineurin in amyotrophic lateral sclerosis.
Hirofumi Maruyama, Hiroyuki Morino, Hidefumi Ito, Yuishin Izumi, Hidemasa Kato, Yasuhito Watanabe, Yoshimi Kinoshita, Masaki Kamada, Hiroyuki Nodera, Hidenori Suzuki,[...]. Nature 2010
835
13

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia.
Axel Freischmidt, Thomas Wieland, Benjamin Richter, Wolfgang Ruf, Veronique Schaeffer, Kathrin Müller, Nicolai Marroquin, Frida Nordin, Annemarie Hübers, Patrick Weydt,[...]. Nat Neurosci 2015
465
13

Association between repeat sizes and clinical and pathological characteristics in carriers of C9ORF72 repeat expansions (Xpansize-72): a cross-sectional cohort study.
Marka van Blitterswijk, Mariely DeJesus-Hernandez, Ellis Niemantsverdriet, Melissa E Murray, Michael G Heckman, Nancy N Diehl, Patricia H Brown, Matthew C Baker, NiCole A Finch, Peter O Bauer,[...]. Lancet Neurol 2013
179
13

The changing scene of amyotrophic lateral sclerosis.
Wim Robberecht, Thomas Philips. Nat Rev Neurosci 2013
629
13

The C9ORF72 GGGGCC expansion forms RNA G-quadruplex inclusions and sequesters hnRNP H to disrupt splicing in ALS brains.
Erin G Conlon, Lei Lu, Aarti Sharma, Takashi Yamazaki, Timothy Tang, Neil A Shneider, James L Manley. Elife 2016
134
13


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.