A citation-based method for searching scientific literature

C A Gutekunst, S H Li, H Yi, J S Mulroy, S Kuemmerle, R Jones, D Rye, R J Ferrante, S M Hersch, X J Li. J Neurosci 1999
Times Cited: 620







List of co-cited articles
1390 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
62


Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
36

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
35

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
26

Neuropathological classification of Huntington's disease.
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
24

Huntington disease.
J P Vonsattel, M DiFiglia. J Neuropathol Exp Neurol 1998
24


Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.
E Scherzinger, R Lurz, M Turmaine, L Mangiarini, B Hollenbach, R Hasenbank, G P Bates, S W Davies, H Lehrach, E E Wanker. Cell 1997
19

The Biology of Huntingtin.
Frédéric Saudou, Sandrine Humbert. Neuron 2016
388
19

Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
933
18

Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.
Liliana B Menalled, Andrea E Kudwa, Sam Miller, Jon Fitzpatrick, Judy Watson-Johnson, Nicole Keating, Melinda Ruiz, Richard Mushlin, William Alosio, Kristi McConnell,[...]. PLoS One 2012
235
16

Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease.
Christian Landles, Kirupa Sathasivam, Andreas Weiss, Ben Woodman, Hilary Moffitt, Steve Finkbeiner, Banghua Sun, Juliette Gafni, Lisa M Ellerby, Yvon Trottier,[...]. J Biol Chem 2010
218
16

Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.
Michelle Gray, Dyna I Shirasaki, Carlos Cepeda, Véronique M André, Brian Wilburn, Xiao-Hong Lu, Jifang Tao, Irene Yamazaki, Shi-Hua Li, Yi E Sun,[...]. J Neurosci 2008
443
16

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.
Kirupa Sathasivam, Andreas Neueder, Theresa A Gipson, Christian Landles, Agnesska C Benjamin, Marie K Bondulich, Donna L Smith, Richard L M Faull, Raymund A C Roos, David Howland,[...]. Proc Natl Acad Sci U S A 2013
275
15

Molecular mechanisms and potential therapeutical targets in Huntington's disease.
Chiara Zuccato, Marta Valenza, Elena Cattaneo. Physiol Rev 2010
560
14

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
791
14

Huntington disease: natural history, biomarkers and prospects for therapeutics.
Christopher A Ross, Elizabeth H Aylward, Edward J Wild, Douglas R Langbehn, Jeffrey D Long, John H Warner, Rachael I Scahill, Blair R Leavitt, Julie C Stout, Jane S Paulsen,[...]. Nat Rev Neurol 2014
554
14

Regional and cellular gene expression changes in human Huntington's disease brain.
Angela Hodges, Andrew D Strand, Aaron K Aragaki, Alexandre Kuhn, Thierry Sengstag, Gareth Hughes, Lyn A Elliston, Cathy Hartog, Darlene R Goldstein, Doris Thu,[...]. Hum Mol Genet 2006
530
13

Huntington disease.
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
615
13

Protein aggregates in Huntington's disease.
Montserrat Arrasate, Steven Finkbeiner. Exp Neurol 2012
193
12


Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin.
G Schilling, M W Becher, A H Sharp, H A Jinnah, K Duan, J A Kotzuk, H H Slunt, T Ratovitski, J K Cooper, N A Jenkins,[...]. Hum Mol Genet 1999
584
12

Huntington's disease.
Francis O Walker. Lancet 2007
11


Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats.
Liliana B Menalled, Jessica D Sison, Ioannis Dragatsis, Scott Zeitlin, Marie-Françoise Chesselet. J Comp Neurol 2003
337
11

Neurological abnormalities in a knock-in mouse model of Huntington's disease.
C H Lin, S Tallaksen-Greene, W M Chien, J A Cearley, W S Jackson, A B Crouse, S Ren, X J Li, R L Albin, P J Detloff. Hum Mol Genet 2001
444
11

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
587
10

Huntington aggregates may not predict neuronal death in Huntington's disease.
S Kuemmerle, C A Gutekunst, A M Klein, X J Li, S H Li, M F Beal, S M Hersch, R J Ferrante. Ann Neurol 1999
270
10

Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients.
Edward J Wild, Roberto Boggio, Douglas Langbehn, Nicola Robertson, Salman Haider, James R C Miller, Henrik Zetterberg, Blair R Leavitt, Rainer Kuhn, Sarah J Tabrizi,[...]. J Clin Invest 2015
128
10

Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse.
V C Wheeler, W Auerbach, J K White, J Srinidhi, A Auerbach, A Ryan, M P Duyao, V Vrbanac, M Weaver, J F Gusella,[...]. Hum Mol Genet 1999
279
10

The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease.
S E Andrew, Y P Goldberg, B Kremer, H Telenius, J Theilmann, S Adam, E Starr, F Squitieri, B Lin, M A Kalchman. Nat Genet 1993
808
10

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.
Brinda Ravikumar, Coralie Vacher, Zdenek Berger, Janet E Davies, Shouqing Luo, Lourdes G Oroz, Francesco Scaravilli, Douglas F Easton, Rainer Duden, Cahir J O'Kane,[...]. Nat Genet 2004
10

Suppression of neuropil aggregates and neurological symptoms by an intracellular antibody implicates the cytoplasmic toxicity of mutant huntingtin.
Chuan-En Wang, Hui Zhou, John R McGuire, Vincenzo Cerullo, Brendan Lee, Shi-Hua Li, Xiao-Jiang Li. J Cell Biol 2008
82
12

Mutant huntingtin fragments form oligomers in a polyglutamine length-dependent manner in vitro and in vivo.
Justin Legleiter, Emily Mitchell, Gregor P Lotz, Ellen Sapp, Cheping Ng, Marian DiFiglia, Leslie M Thompson, Paul J Muchowski. J Biol Chem 2010
141
10

Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy.
K B Kegel, M Kim, E Sapp, C McIntyre, J G Castaño, N Aronin, M DiFiglia. J Neurosci 2000
368
10

SUMO modification of Huntingtin and Huntington's disease pathology.
Joan S Steffan, Namita Agrawal, Judit Pallos, Erica Rockabrand, Lloyd C Trotman, Natalia Slepko, Katalin Illes, Tamas Lukacsovich, Ya-Zhen Zhu, Elena Cattaneo,[...]. Science 2004
497
10

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology.
E Scherzinger, A Sittler, K Schweiger, V Heiser, R Lurz, R Hasenbank, G P Bates, H Lehrach, E E Wanker. Proc Natl Acad Sci U S A 1999
527
10


Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila.
Shermali Gunawardena, Lu-Shiun Her, Richard G Brusch, Robert A Laymon, Ingrid R Niesman, Beth Gordesky-Gold, Louis Sintasath, Nancy M Bonini, Lawrence S B Goldstein. Neuron 2003
471
10

Proteases acting on mutant huntingtin generate cleaved products that differentially build up cytoplasmic and nuclear inclusions.
Astrid Lunkes, Katrin S Lindenberg, Léa Ben-Haïem, Chantal Weber, Didier Devys, G Bernhard Landwehrmeyer, Jean-Louis Mandel, Yvon Trottier. Mol Cell 2002
277
10

Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis.
Holly B Kordasiewicz, Lisa M Stanek, Edward V Wancewicz, Curt Mazur, Melissa M McAlonis, Kimberly A Pytel, Jonathan W Artates, Andreas Weiss, Seng H Cheng, Lamya S Shihabuddin,[...]. Neuron 2012
479
10


The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
J S Steffan, A Kazantsev, O Spasic-Boskovic, M Greenwald, Y Z Zhu, H Gohler, E E Wanker, G P Bates, D E Housman, L M Thompson. Proc Natl Acad Sci U S A 2000
789
10


Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release.
Yeun Su Choo, Gail V W Johnson, Marcy MacDonald, Peter J Detloff, Mathieu Lesort. Hum Mol Genet 2004
351
9

N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking.
Adam L Orr, Shihua Li, Chuan-En Wang, He Li, Jianjun Wang, Juan Rong, Xingshun Xu, Pier Giorgio Mastroberardino, J Timothy Greenamyre, Xiao-Jiang Li. J Neurosci 2008
286
9


Potential function for the Huntingtin protein as a scaffold for selective autophagy.
Joseph Ochaba, Tamás Lukacsovich, George Csikos, Shuqiu Zheng, Julia Margulis, Lisa Salazar, Kai Mao, Alice L Lau, Sylvia Y Yeung, Sandrine Humbert,[...]. Proc Natl Acad Sci U S A 2014
166
9

Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro.
Eugenia Trushina, Roy B Dyer, John D Badger, Daren Ure, Lars Eide, David D Tran, Brent T Vrieze, Valerie Legendre-Guillemin, Peter S McPherson, Bhaskar S Mandavilli,[...]. Mol Cell Biol 2004
372
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.