A citation-based method for searching scientific literature

K L Rudolph, S Chang, H W Lee, M Blasco, G J Gottlieb, C Greider, R A DePinho. Cell 1999
Times Cited: 977







List of co-cited articles
1415 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Telomere shortening and tumor formation by mouse cells lacking telomerase RNA.
M A Blasco, H W Lee, M P Hande, E Samper, P M Lansdorp, R A DePinho, C W Greider. Cell 1997
34

The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
33

Telomeres shorten during ageing of human fibroblasts.
C B Harley, A B Futcher, C W Greider. Nature 1990
23

Extension of life-span by introduction of telomerase into normal human cells.
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
21

A DNA damage checkpoint response in telomere-initiated senescence.
Fabrizio d'Adda di Fagagna, Philip M Reaper, Lorena Clay-Farrace, Heike Fiegler, Philippa Carr, Thomas Von Zglinicki, Gabriele Saretzki, Nigel P Carter, Stephen P Jackson. Nature 2003
19

Essential role of mouse telomerase in highly proliferative organs.
H W Lee, M A Blasco, G J Gottlieb, J W Horner, C W Greider, R A DePinho. Nature 1998
991
18

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.
Mariela Jaskelioff, Florian L Muller, Ji-Hye Paik, Emily Thomas, Shan Jiang, Andrew C Adams, Ergun Sahin, Maria Kost-Alimova, Alexei Protopopov, Juan Cadiñanos,[...]. Nature 2011
446
17

The serial cultivation of human diploid cell strains.
L HAYFLICK, P S MOORHEAD. Exp Cell Res 1961
16

Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.
Darren J Baker, Bennett G Childs, Matej Durik, Melinde E Wijers, Cynthia J Sieben, Jian Zhong, Rachel A Saltness, Karthik B Jeganathan, Grace Casaclang Verzosa, Abdulmohammad Pezeshki,[...]. Nature 2016
16

The telomere syndromes.
Mary Armanios, Elizabeth H Blackburn. Nat Rev Genet 2012
541
14

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
14

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.
Jean-Philippe Coppé, Christopher K Patil, Francis Rodier, Yu Sun, Denise P Muñoz, Joshua Goldstein, Peter S Nelson, Pierre-Yves Desprez, Judith Campisi. PLoS Biol 2008
12

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis.
L Chin, S E Artandi, Q Shen, A Tam, S L Lee, G J Gottlieb, C W Greider, R A DePinho. Cell 1999
729
12


Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
12

Telomerase reverse transcriptase delays aging in cancer-resistant mice.
Antonia Tomás-Loba, Ignacio Flores, Pablo J Fernández-Marcos, María L Cayuela, Antonio Maraver, Agueda Tejera, Consuelo Borrás, Ander Matheu, Peter Klatt, Juana M Flores,[...]. Cell 2008
266
12

The role of senescent cells in ageing.
Jan M van Deursen. Nature 2014
986
12

Telomere dysfunction induces metabolic and mitochondrial compromise.
Ergün Sahin, Simona Colla, Marc Liesa, Javid Moslehi, Florian L Müller, Mira Guo, Marcus Cooper, Darrell Kotton, Attila J Fabian, Carl Walkey,[...]. Nature 2011
778
12

Cellular senescence: from physiology to pathology.
Daniel Muñoz-Espín, Manuel Serrano. Nat Rev Mol Cell Biol 2014
11

Mammalian telomeres end in a large duplex loop.
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
11

Age-related clonal hematopoiesis associated with adverse outcomes.
Siddhartha Jaiswal, Pierre Fontanillas, Jason Flannick, Alisa Manning, Peter V Grauman, Brenton G Mar, R Coleman Lindsley, Craig H Mermel, Noel Burtt, Alejandro Chavez,[...]. N Engl J Med 2014
11

Cellular senescence: when bad things happen to good cells.
Judith Campisi, Fabrizio d'Adda di Fagagna. Nat Rev Mol Cell Biol 2007
11

Telomere measurement by quantitative PCR.
Richard M Cawthon. Nucleic Acids Res 2002
11

Disease states associated with telomerase deficiency appear earlier in mice with short telomeres.
E Herrera, E Samper, J Martín-Caballero, J M Flores, H W Lee, M A Blasco. EMBO J 1999
354
10

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice.
S E Artandi, S Chang, S L Lee, S Alson, G J Gottlieb, L Chin, R A DePinho. Nature 2000
830
10



How shelterin protects mammalian telomeres.
Wilhelm Palm, Titia de Lange. Annu Rev Genet 2008
10


Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence.
Graeme Hewitt, Diana Jurk, Francisco D M Marques, Clara Correia-Melo, Timothy Hardy, Agata Gackowska, Rhys Anderson, Morgan Taschuk, Jelena Mann, João F Passos. Nat Commun 2012
412
10

Short telomeres are sufficient to cause the degenerative defects associated with aging.
Mary Armanios, Jonathan K Alder, Erin M Parry, Baktiar Karim, Margaret A Strong, Carol W Greider. Am J Hum Genet 2009
147
10

Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation.
Aaheli Roy Choudhury, Zhenyu Ju, Meta W Djojosubroto, Andrea Schienke, Andre Lechel, Sonja Schaetzlein, Hong Jiang, Anna Stepczynska, Chunfang Wang, Jan Buer,[...]. Nat Genet 2007
305
9


Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.
Agnel Sfeir, Settapong T Kosiyatrakul, Dirk Hockemeyer, Sheila L MacRae, Jan Karlseder, Carl L Schildkraut, Titia de Lange. Cell 2009
633
9


Oxidative stress shortens telomeres.
Thomas von Zglinicki. Trends Biochem Sci 2002
9

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.
Jianhui Chang, Yingying Wang, Lijian Shao, Remi-Martin Laberge, Marco Demaria, Judith Campisi, Krishnamurthy Janakiraman, Norman E Sharpless, Sheng Ding, Wei Feng,[...]. Nat Med 2016
653
9

The senescence-associated secretory phenotype: the dark side of tumor suppression.
Jean-Philippe Coppé, Pierre-Yves Desprez, Ana Krtolica, Judith Campisi. Annu Rev Pathol 2010
9

Essential role of limiting telomeres in the pathogenesis of Werner syndrome.
Sandy Chang, Asha S Multani, Noelia G Cabrera, Maria L Naylor, Purnima Laud, David Lombard, Sen Pathak, Leonard Guarente, Ronald A DePinho. Nat Genet 2004
325
8

Origin of concatemeric T7 DNA.
J D Watson. Nat New Biol 1972
8


TRF2 protects human telomeres from end-to-end fusions.
B van Steensel, A Smogorzewska, T de Lange. Cell 1998
8

Effects of telomerase and telomere length on epidermal stem cell behavior.
Ignacio Flores, María L Cayuela, María A Blasco. Science 2005
295
8

Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer.
Bruno Bernardes de Jesus, Elsa Vera, Kerstin Schneeberger, Agueda M Tejera, Eduard Ayuso, Fatima Bosch, Maria A Blasco. EMBO Mol Med 2012
207
8

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age.
Derrick J Rossi, David Bryder, Jun Seita, Andre Nussenzweig, Jan Hoeijmakers, Irving L Weissman. Nature 2007
723
8

Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence.
Giulio Genovese, Anna K Kähler, Robert E Handsaker, Johan Lindberg, Samuel A Rose, Samuel F Bakhoum, Kimberly Chambert, Eran Mick, Benjamin M Neale, Menachem Fromer,[...]. N Engl J Med 2014
8

Age-related mutations associated with clonal hematopoietic expansion and malignancies.
Mingchao Xie, Charles Lu, Jiayin Wang, Michael D McLellan, Kimberly J Johnson, Michael C Wendl, Joshua F McMichael, Heather K Schmidt, Venkata Yellapantula, Christopher A Miller,[...]. Nat Med 2014
905
8

Association between telomere length in blood and mortality in people aged 60 years or older.
Richard M Cawthon, Ken R Smith, Elizabeth O'Brien, Anna Sivatchenko, Richard A Kerber. Lancet 2003
8

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.
C M Counter, A A Avilion, C E LeFeuvre, N G Stewart, C W Greider, C B Harley, S Bacchetti. EMBO J 1992
7



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.