R J Carter, L A Lione, T Humby, L Mangiarini, A Mahal, G P Bates, S B Dunnett, A J Morton. J Neurosci 1999
Times Cited: 696
Times Cited: 696
Times Cited
Times Co-cited
Similarity
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
34
16
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
14
Neurological abnormalities in a knock-in mouse model of Huntington's disease.
C H Lin, S Tallaksen-Greene, W M Chien, J A Cearley, W S Jackson, A B Crouse, S Ren, X J Li, R L Albin, P J Detloff. Hum Mol Genet 2001
C H Lin, S Tallaksen-Greene, W M Chien, J A Cearley, W S Jackson, A B Crouse, S Ren, X J Li, R L Albin, P J Detloff. Hum Mol Genet 2001
12
Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models.
Liliana Menalled, Bassem F El-Khodor, Monica Patry, Mayte Suárez-Fariñas, Samantha J Orenstein, Benjamin Zahasky, Christina Leahy, Vanessa Wheeler, X William Yang, Marcy MacDonald,[...]. Neurobiol Dis 2009
Liliana Menalled, Bassem F El-Khodor, Monica Patry, Mayte Suárez-Fariñas, Samantha J Orenstein, Benjamin Zahasky, Christina Leahy, Vanessa Wheeler, X William Yang, Marcy MacDonald,[...]. Neurobiol Dis 2009
11
Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.
Michelle Gray, Dyna I Shirasaki, Carlos Cepeda, Véronique M André, Brian Wilburn, Xiao-Hong Lu, Jifang Tao, Irene Yamazaki, Shi-Hua Li, Yi E Sun,[...]. J Neurosci 2008
Michelle Gray, Dyna I Shirasaki, Carlos Cepeda, Véronique M André, Brian Wilburn, Xiao-Hong Lu, Jifang Tao, Irene Yamazaki, Shi-Hua Li, Yi E Sun,[...]. J Neurosci 2008
9
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
9
Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.
Liliana B Menalled, Andrea E Kudwa, Sam Miller, Jon Fitzpatrick, Judy Watson-Johnson, Nicole Keating, Melinda Ruiz, Richard Mushlin, William Alosio, Kristi McConnell,[...]. PLoS One 2012
Liliana B Menalled, Andrea E Kudwa, Sam Miller, Jon Fitzpatrick, Judy Watson-Johnson, Nicole Keating, Melinda Ruiz, Richard Mushlin, William Alosio, Kristi McConnell,[...]. PLoS One 2012
9
Intrabody gene therapy ameliorates motor, cognitive, and neuropathological symptoms in multiple mouse models of Huntington's disease.
Amber L Southwell, Jan Ko, Paul H Patterson. J Neurosci 2009
Amber L Southwell, Jan Ko, Paul H Patterson. J Neurosci 2009
9
Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
9
Chronology of behavioral symptoms and neuropathological sequela in R6/2 Huntington's disease transgenic mice.
Edward C Stack, James K Kubilus, Karen Smith, Kerry Cormier, Steven J Del Signore, Emmanuel Guelin, Hoon Ryu, Steven M Hersch, Robert J Ferrante. J Comp Neurol 2005
Edward C Stack, James K Kubilus, Karen Smith, Kerry Cormier, Steven J Del Signore, Emmanuel Guelin, Hoon Ryu, Steven M Hersch, Robert J Ferrante. J Comp Neurol 2005
9
Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin.
G Schilling, M W Becher, A H Sharp, H A Jinnah, K Duan, J A Kotzuk, H H Slunt, T Ratovitski, J K Cooper, N A Jenkins,[...]. Hum Mol Genet 1999
G Schilling, M W Becher, A H Sharp, H A Jinnah, K Duan, J A Kotzuk, H H Slunt, T Ratovitski, J K Cooper, N A Jenkins,[...]. Hum Mol Genet 1999
8
Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation.
L A Lione, R J Carter, M J Hunt, G P Bates, A J Morton, S B Dunnett. J Neurosci 1999
L A Lione, R J Carter, M J Hunt, G P Bates, A J Morton, S B Dunnett. J Neurosci 1999
8
Neuropathological classification of Huntington's disease.
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
8
A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.
J G Hodgson, N Agopyan, C A Gutekunst, B R Leavitt, F LePiane, R Singaraja, D J Smith, N Bissada, K McCutcheon, J Nasir,[...]. Neuron 1999
J G Hodgson, N Agopyan, C A Gutekunst, B R Leavitt, F LePiane, R Singaraja, D J Smith, N Bissada, K McCutcheon, J Nasir,[...]. Neuron 1999
7
The use of the R6 transgenic mouse models of Huntington's disease in attempts to develop novel therapeutic strategies.
Jia Yi Li, Natalija Popovic, Patrik Brundin. NeuroRx 2005
Jia Yi Li, Natalija Popovic, Patrik Brundin. NeuroRx 2005
7
Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment.
D C Rogers, E M Fisher, S D Brown, J Peters, A J Hunter, J E Martin. Mamm Genome 1997
D C Rogers, E M Fisher, S D Brown, J Peters, A J Hunter, J E Martin. Mamm Genome 1997
7
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
7
Normal huntingtin function: an alternative approach to Huntington's disease.
Elena Cattaneo, Chiara Zuccato, Marzia Tartari. Nat Rev Neurosci 2005
Elena Cattaneo, Chiara Zuccato, Marzia Tartari. Nat Rev Neurosci 2005
7
Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington's disease.
Taneli Heikkinen, Kimmo Lehtimäki, Nina Vartiainen, Jukka Puoliväli, Susan J Hendricks, Jack R Glaser, Amyaouch Bradaia, Kristian Wadel, Chrystelle Touller, Outi Kontkanen,[...]. PLoS One 2012
Taneli Heikkinen, Kimmo Lehtimäki, Nina Vartiainen, Jukka Puoliväli, Susan J Hendricks, Jack R Glaser, Amyaouch Bradaia, Kristian Wadel, Chrystelle Touller, Outi Kontkanen,[...]. PLoS One 2012
7
Motor coordination and balance in rodents.
R J Carter, J Morton, S B Dunnett. Curr Protoc Neurosci 2001
R J Carter, J Morton, S B Dunnett. Curr Protoc Neurosci 2001
6
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease.
C Zuccato, A Ciammola, D Rigamonti, B R Leavitt, D Goffredo, L Conti, M E MacDonald, R M Friedlander, V Silani, M R Hayden,[...]. Science 2001
C Zuccato, A Ciammola, D Rigamonti, B R Leavitt, D Goffredo, L Conti, M E MacDonald, R M Friedlander, V Silani, M R Hayden,[...]. Science 2001
6
Mouse models of Huntington's disease.
Liliana B Menalled, Marie-Françoise Chesselet. Trends Pharmacol Sci 2002
Liliana B Menalled, Marie-Françoise Chesselet. Trends Pharmacol Sci 2002
6
Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
6
Mouse models of Huntington's disease and methodological considerations for therapeutic trials.
Robert J Ferrante. Biochim Biophys Acta 2009
Robert J Ferrante. Biochim Biophys Acta 2009
5
Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice.
M A Hickey, A Kosmalska, J Enayati, R Cohen, S Zeitlin, M S Levine, M-F Chesselet. Neuroscience 2008
M A Hickey, A Kosmalska, J Enayati, R Cohen, S Zeitlin, M S Levine, M-F Chesselet. Neuroscience 2008
5
Multiple sources of striatal inhibition are differentially affected in Huntington's disease mouse models.
Carlos Cepeda, Laurie Galvan, Sandra M Holley, Shilpa P Rao, Véronique M André, Elian P Botelho, Jane Y Chen, Joseph B Watson, Karl Deisseroth, Michael S Levine. J Neurosci 2013
Carlos Cepeda, Laurie Galvan, Sandra M Holley, Shilpa P Rao, Véronique M André, Elian P Botelho, Jane Y Chen, Joseph B Watson, Karl Deisseroth, Michael S Levine. J Neurosci 2013
6
Huntington's disease: can mice lead the way to treatment?
Zachary R Crook, David Housman. Neuron 2011
Zachary R Crook, David Housman. Neuron 2011
5
Huntington disease models and human neuropathology: similarities and differences.
Jean Paul G Vonsattel. Acta Neuropathol 2008
Jean Paul G Vonsattel. Acta Neuropathol 2008
5
Early behavioral deficits in R6/2 mice suitable for use in preclinical drug testing.
M A Hickey, K Gallant, G G Gross, M S Levine, Marie-Françoise Chesselet. Neurobiol Dis 2005
M A Hickey, K Gallant, G G Gross, M S Levine, Marie-Françoise Chesselet. Neurobiol Dis 2005
5
Differential electrophysiological changes in striatal output neurons in Huntington's disease.
Véronique M André, Carlos Cepeda, Yvette E Fisher, My Huynh, Nora Bardakjian, Sumedha Singh, X William Yang, Michael S Levine. J Neurosci 2011
Véronique M André, Carlos Cepeda, Yvette E Fisher, My Huynh, Nora Bardakjian, Sumedha Singh, X William Yang, Michael S Levine. J Neurosci 2011
5
Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease.
Nan Wang, Michelle Gray, Xiao-Hong Lu, Jeffrey P Cantle, Sandra M Holley, Erin Greiner, Xiaofeng Gu, Dyna Shirasaki, Carlos Cepeda, Yuqing Li,[...]. Nat Med 2014
Nan Wang, Michelle Gray, Xiao-Hong Lu, Jeffrey P Cantle, Sandra M Holley, Erin Greiner, Xiaofeng Gu, Dyna Shirasaki, Carlos Cepeda, Yuqing Li,[...]. Nat Med 2014
5
Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice.
G J Klapstein, R S Fisher, H Zanjani, C Cepeda, E S Jokel, M F Chesselet, M S Levine. J Neurophysiol 2001
G J Klapstein, R S Fisher, H Zanjani, C Cepeda, E S Jokel, M F Chesselet, M S Levine. J Neurophysiol 2001
5
The corticostriatal pathway in Huntington's disease.
Carlos Cepeda, Nanping Wu, Véronique M André, Damian M Cummings, Michael S Levine. Prog Neurobiol 2007
Carlos Cepeda, Nanping Wu, Véronique M André, Damian M Cummings, Michael S Levine. Prog Neurobiol 2007
5
Cortical efferents lacking mutant huntingtin improve striatal neuronal activity and behavior in a conditional mouse model of Huntington's disease.
Ana María Estrada-Sánchez, Courtney L Burroughs, Stephen Cavaliere, Scott J Barton, Shirley Chen, X William Yang, George V Rebec. J Neurosci 2015
Ana María Estrada-Sánchez, Courtney L Burroughs, Stephen Cavaliere, Scott J Barton, Shirley Chen, X William Yang, George V Rebec. J Neurosci 2015
13
Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats.
Liliana B Menalled, Jessica D Sison, Ioannis Dragatsis, Scott Zeitlin, Marie-Françoise Chesselet. J Comp Neurol 2003
Liliana B Menalled, Jessica D Sison, Ioannis Dragatsis, Scott Zeitlin, Marie-Françoise Chesselet. J Comp Neurol 2003
5
The mouse beam walking assay offers improved sensitivity over the mouse rotarod in determining motor coordination deficits induced by benzodiazepines.
Joanna L Stanley, Rachael J Lincoln, Terry A Brown, Louise M McDonald, Gerard R Dawson, David S Reynolds. J Psychopharmacol 2005
Joanna L Stanley, Rachael J Lincoln, Terry A Brown, Louise M McDonald, Gerard R Dawson, David S Reynolds. J Psychopharmacol 2005
4
The detection and measurement of locomotor deficits in a transgenic mouse model of Huntington's disease are task- and protocol-dependent: influence of non-motor factors on locomotor function.
Patrick N Pallier, Cheney J G Drew, A Jennifer Morton. Brain Res Bull 2009
Patrick N Pallier, Cheney J G Drew, A Jennifer Morton. Brain Res Bull 2009
8
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
4
Huntington disease: natural history, biomarkers and prospects for therapeutics.
Christopher A Ross, Elizabeth H Aylward, Edward J Wild, Douglas R Langbehn, Jeffrey D Long, John H Warner, Rachael I Scahill, Blair R Leavitt, Julie C Stout, Jane S Paulsen,[...]. Nat Rev Neurol 2014
Christopher A Ross, Elizabeth H Aylward, Edward J Wild, Douglas R Langbehn, Jeffrey D Long, John H Warner, Rachael I Scahill, Blair R Leavitt, Julie C Stout, Jane S Paulsen,[...]. Nat Rev Neurol 2014
4
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.
Brinda Ravikumar, Coralie Vacher, Zdenek Berger, Janet E Davies, Shouqing Luo, Lourdes G Oroz, Francesco Scaravilli, Douglas F Easton, Rainer Duden, Cahir J O'Kane,[...]. Nat Genet 2004
Brinda Ravikumar, Coralie Vacher, Zdenek Berger, Janet E Davies, Shouqing Luo, Lourdes G Oroz, Francesco Scaravilli, Douglas F Easton, Rainer Duden, Cahir J O'Kane,[...]. Nat Genet 2004
4
Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease.
Austen J Milnerwood, Lynn A Raymond. Trends Neurosci 2010
Austen J Milnerwood, Lynn A Raymond. Trends Neurosci 2010
4
FTY720 (fingolimod) is a neuroprotective and disease-modifying agent in cellular and mouse models of Huntington disease.
Alba Di Pardo, Enrico Amico, Mariagrazia Favellato, Roberta Castrataro, Sergio Fucile, Ferdinando Squitieri, Vittorio Maglione. Hum Mol Genet 2014
Alba Di Pardo, Enrico Amico, Mariagrazia Favellato, Roberta Castrataro, Sergio Fucile, Ferdinando Squitieri, Vittorio Maglione. Hum Mol Genet 2014
5
Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice.
Alba Di Pardo, Vittorio Maglione, Melanie Alpaugh, Melanie Horkey, Randy S Atwal, Jenny Sassone, Andrea Ciammola, Joan S Steffan, Karim Fouad, Ray Truant,[...]. Proc Natl Acad Sci U S A 2012
Alba Di Pardo, Vittorio Maglione, Melanie Alpaugh, Melanie Horkey, Randy S Atwal, Jenny Sassone, Andrea Ciammola, Joan S Steffan, Karim Fouad, Ray Truant,[...]. Proc Natl Acad Sci U S A 2012
4
Chronic treatment with 17-DMAG improves balance and coordination in a new mouse model of Machado-Joseph disease.
Anabela Silva-Fernandes, Sara Duarte-Silva, Andreia Neves-Carvalho, Marina Amorim, Carina Soares-Cunha, Pedro Oliveira, Kenneth Thirstrup, Andreia Teixeira-Castro, Patrícia Maciel. Neurotherapeutics 2014
Anabela Silva-Fernandes, Sara Duarte-Silva, Andreia Neves-Carvalho, Marina Amorim, Carina Soares-Cunha, Pedro Oliveira, Kenneth Thirstrup, Andreia Teixeira-Castro, Patrícia Maciel. Neurotherapeutics 2014
5
Functional assessments in the rodent stroke model.
Krystal L Schaar, Miranda M Brenneman, Sean I Savitz. Exp Transl Stroke Med 2010
Krystal L Schaar, Miranda M Brenneman, Sean I Savitz. Exp Transl Stroke Med 2010
4
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.