D Wotton, R S Lo, S Lee, J Massagué. Cell 1999
Times Cited: 451
Times Cited: 451
Times Cited
Times Co-cited
Similarity
A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif.
E Bertolino, B Reimund, D Wildt-Perinic, R G Clerc. J Biol Chem 1995
E Bertolino, B Reimund, D Wildt-Perinic, R G Clerc. J Biol Chem 1995
33
Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination.
K W Gripp, D Wotton, M C Edwards, E Roessler, L Ades, P Meinecke, A Richieri-Costa, E H Zackai, J Massagué, M Muenke,[...]. Nat Genet 2000
K W Gripp, D Wotton, M C Edwards, E Roessler, L Ades, P Meinecke, A Richieri-Costa, E H Zackai, J Massagué, M Muenke,[...]. Nat Genet 2000
25
TGIF inhibits retinoid signaling.
Laurent Bartholin, Shannon E Powers, Tiffany A Melhuish, Samuel Lasse, Michael Weinstein, David Wotton. Mol Cell Biol 2006
Laurent Bartholin, Shannon E Powers, Tiffany A Melhuish, Samuel Lasse, Michael Weinstein, David Wotton. Mol Cell Biol 2006
26
Multiple modes of repression by the Smad transcriptional corepressor TGIF.
D Wotton, R S Lo, L A Swaby, J Massagué. J Biol Chem 1999
D Wotton, R S Lo, L A Swaby, J Massagué. J Biol Chem 1999
23
Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.
Kenichiro Taniguchi, Anoush E Anderson, Ann E Sutherland, David Wotton. PLoS Genet 2012
Kenichiro Taniguchi, Anoush E Anderson, Ann E Sutherland, David Wotton. PLoS Genet 2012
33
TGIF governs a feed-forward network that empowers Wnt signaling to drive mammary tumorigenesis.
Ming-Zhu Zhang, Olivier Ferrigno, Zhe Wang, Mutsuko Ohnishi, Céline Prunier, Laurence Levy, Mohammed Razzaque, Williams C Horne, Damian Romero, Guri Tzivion,[...]. Cancer Cell 2015
Ming-Zhu Zhang, Olivier Ferrigno, Zhe Wang, Mutsuko Ohnishi, Céline Prunier, Laurence Levy, Mohammed Razzaque, Williams C Horne, Damian Romero, Guri Tzivion,[...]. Cancer Cell 2015
46
Nuclear retention of the tumor suppressor cPML by the homeodomain protein TGIF restricts TGF-beta signaling.
Su Ryeon Seo, Nathalie Ferrand, Nourdine Faresse, Céline Prunier, Lucile Abécassis, Marcia Pessah, Marie-Francoise Bourgeade, Azeddine Atfi. Mol Cell 2006
Su Ryeon Seo, Nathalie Ferrand, Nourdine Faresse, Céline Prunier, Lucile Abécassis, Marcia Pessah, Marie-Francoise Bourgeade, Azeddine Atfi. Mol Cell 2006
28
Transforming growth-interacting factor (TGIF) regulates proliferation and differentiation of human myeloid leukemia cells.
Rizwan Hamid, Stephen J Brandt. Mol Oncol 2009
Rizwan Hamid, Stephen J Brandt. Mol Oncol 2009
36
Maternal Tgif is required for vascularization of the embryonic placenta.
Laurent Bartholin, Tiffany A Melhuish, Shannon E Powers, Sophie Goddard-Léon, Isabelle Treilleux, Ann E Sutherland, David Wotton. Dev Biol 2008
Laurent Bartholin, Tiffany A Melhuish, Shannon E Powers, Sophie Goddard-Léon, Isabelle Treilleux, Ann E Sutherland, David Wotton. Dev Biol 2008
41
The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradation.
Su Ryeon Seo, François Lallemand, Nathalie Ferrand, Marcia Pessah, Sébastien L'Hoste, Jacques Camonis, Azeddine Atfi. EMBO J 2004
Su Ryeon Seo, François Lallemand, Nathalie Ferrand, Marcia Pessah, Sébastien L'Hoste, Jacques Camonis, Azeddine Atfi. EMBO J 2004
16
Targeted disruption of Tgif, the mouse ortholog of a human holoprosencephaly gene, does not result in holoprosencephaly in mice.
Jun Shen, Christopher A Walsh. Mol Cell Biol 2005
Jun Shen, Christopher A Walsh. Mol Cell Biol 2005
23
The Smad transcriptional corepressor TGIF recruits mSin3.
D Wotton, P S Knoepfler, C D Laherty, R N Eisenman, J Massagué. Cell Growth Differ 2001
D Wotton, P S Knoepfler, C D Laherty, R N Eisenman, J Massagué. Cell Growth Differ 2001
15
TGIF2 interacts with histone deacetylase 1 and represses transcription.
T A Melhuish, C M Gallo, D Wotton. J Biol Chem 2001
T A Melhuish, C M Gallo, D Wotton. J Biol Chem 2001
14
Tgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation.
Shannon E Powers, Kenichiro Taniguchi, Weiwei Yen, Tiffany A Melhuish, Jun Shen, Christopher A Walsh, Ann E Sutherland, David Wotton. Development 2010
Shannon E Powers, Kenichiro Taniguchi, Weiwei Yen, Tiffany A Melhuish, Jun Shen, Christopher A Walsh, Ann E Sutherland, David Wotton. Development 2010
27
Mechanisms of TGF-beta signaling from cell membrane to the nucleus.
Yigong Shi, Joan Massagué. Cell 2003
Yigong Shi, Joan Massagué. Cell 2003
12
The interaction of the carboxyl terminus-binding protein with the Smad corepressor TGIF is disrupted by a holoprosencephaly mutation in TGIF.
T A Melhuish, D Wotton. J Biol Chem 2000
T A Melhuish, D Wotton. J Biol Chem 2000
13
Functional analysis of mutations in TGIF associated with holoprosencephaly.
Kenia B El-Jaick, Shannon E Powers, Laurent Bartholin, Kenneth R Myers, Jin Hahn, Ieda M Orioli, Maia Ouspenskaia, Felicitas Lacbawan, Erich Roessler, David Wotton,[...]. Mol Genet Metab 2007
Kenia B El-Jaick, Shannon E Powers, Laurent Bartholin, Kenneth R Myers, Jin Hahn, Ieda M Orioli, Maia Ouspenskaia, Felicitas Lacbawan, Erich Roessler, David Wotton,[...]. Mol Genet Metab 2007
21
The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation.
X H Feng, Y Zhang, R Y Wu, R Derynck. Genes Dev 1998
X H Feng, Y Zhang, R Y Wu, R Derynck. Genes Dev 1998
12
Genomic structure, alternative splicing and expression of TG-interacting factor, in human myeloid leukemia blasts and cell lines.
Rizwan Hamid, Johnequia Patterson, Stephen J Brandt. Biochim Biophys Acta 2008
Rizwan Hamid, Johnequia Patterson, Stephen J Brandt. Biochim Biophys Acta 2008
34
Overexpression of TG-interacting factor is associated with worse prognosis in upper urinary tract urothelial carcinoma.
Bi-Wen Yeh, Wen-Jeng Wu, Wei-Ming Li, Ching-Chia Li, Chun-Nung Huang, Wan-Yi Kang, Zi-Miao Liu, Huei-Sheng Huang. Am J Pathol 2012
Bi-Wen Yeh, Wen-Jeng Wu, Wei-Ming Li, Ching-Chia Li, Chun-Nung Huang, Wan-Yi Kang, Zi-Miao Liu, Huei-Sheng Huang. Am J Pathol 2012
39
Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein.
S L Stroschein, W Wang, S Zhou, Q Zhou, K Luo. Science 1999
S L Stroschein, W Wang, S Zhou, Q Zhou, K Luo. Science 1999
10
Amplification and overexpression of TGIF2, a novel homeobox gene of the TALE superclass, in ovarian cancer cell lines.
I Imoto, A Pimkhaokham, T Watanabe, F Saito-Ohara, E Soeda, J Inazawa. Biochem Biophys Res Commun 2000
I Imoto, A Pimkhaokham, T Watanabe, F Saito-Ohara, E Soeda, J Inazawa. Biochem Biophys Res Commun 2000
11
Specificity and versatility in tgf-beta signaling through Smads.
Xin-Hua Feng, Rik Derynck. Annu Rev Cell Dev Biol 2005
Xin-Hua Feng, Rik Derynck. Annu Rev Cell Dev Biol 2005
10
TGIF1 promoted the growth and migration of cancer cells in nonsmall cell lung cancer.
Guo Xiang, Yang Yi, He Weiwei, Wu Weiming. Tumour Biol 2015
Guo Xiang, Yang Yi, He Weiwei, Wu Weiming. Tumour Biol 2015
41
Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF.
R S Lo, D Wotton, J Massagué. EMBO J 2001
R S Lo, D Wotton, J Massagué. EMBO J 2001
9
Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription.
Y Yang, C K Hwang, U M D'Souza, S H Lee, E Junn, M M Mouradian. J Biol Chem 2000
Y Yang, C K Hwang, U M D'Souza, S H Lee, E Junn, M M Mouradian. J Biol Chem 2000
13
5'TG3' interacting factor interacts with Sin3A and represses AR-mediated transcription.
M Sharma, Z Sun. Mol Endocrinol 2001
M Sharma, Z Sun. Mol Endocrinol 2001
21
Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals.
T R Bürglin. Nucleic Acids Res 1997
T R Bürglin. Nucleic Acids Res 1997
9
Ski and SnoN, potent negative regulators of TGF-beta signaling.
Julien Deheuninck, Kunxin Luo. Cell Res 2009
Julien Deheuninck, Kunxin Luo. Cell Res 2009
9
PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling.
Xia Lin, Xueyan Duan, Yao-Yun Liang, Ying Su, Katharine H Wrighton, Jianyin Long, Min Hu, Candi M Davis, Jinrong Wang, F Charles Brunicardi,[...]. Cell 2006
Xia Lin, Xueyan Duan, Yao-Yun Liang, Ying Su, Katharine H Wrighton, Jianyin Long, Min Hu, Candi M Davis, Jinrong Wang, F Charles Brunicardi,[...]. Cell 2006
9
Tgf-beta superfamily signaling in embryonic development and homeostasis.
Mary Y Wu, Caroline S Hill. Dev Cell 2009
Mary Y Wu, Caroline S Hill. Dev Cell 2009
9
Physical and functional interaction of SMADs and p300/CBP.
C Pouponnot, L Jayaraman, J Massagué. J Biol Chem 1998
C Pouponnot, L Jayaraman, J Massagué. J Biol Chem 1998
9
Elevated expression of TGIF is involved in lung carcinogenesis.
Yadong Wang, Haiyu Wang, Huiyan Gao, Bing Xu, Wenlong Zhai, Jiangmin Li, Congke Zhang. Tumour Biol 2015
Yadong Wang, Haiyu Wang, Huiyan Gao, Bing Xu, Wenlong Zhai, Jiangmin Li, Congke Zhang. Tumour Biol 2015
60
The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling.
K Luo, S L Stroschein, W Wang, D Chen, E Martens, S Zhou, Q Zhou. Genes Dev 1999
K Luo, S L Stroschein, W Wang, D Chen, E Martens, S Zhou, Q Zhou. Genes Dev 1999
8
TGF-beta signalling from cell membrane to nucleus through SMAD proteins.
C H Heldin, K Miyazono, P ten Dijke. Nature 1997
C H Heldin, K Miyazono, P ten Dijke. Nature 1997
8
TGFbeta signalling: a complex web in cancer progression.
Hiroaki Ikushima, Kohei Miyazono. Nat Rev Cancer 2010
Hiroaki Ikushima, Kohei Miyazono. Nat Rev Cancer 2010
8
Tgif1 represses apolipoprotein gene expression in liver.
Tiffany A Melhuish, David D Chung, Glen A Bjerke, David Wotton. J Cell Biochem 2010
Tiffany A Melhuish, David D Chung, Glen A Bjerke, David Wotton. J Cell Biochem 2010
47
TG-interacting factor 1 acts as a transcriptional repressor of sterol O-acyltransferase 2.
Camilla Pramfalk, Tiffany A Melhuish, David Wotton, Zhao-Yan Jiang, Mats Eriksson, Paolo Parini. J Lipid Res 2014
Camilla Pramfalk, Tiffany A Melhuish, David Wotton, Zhao-Yan Jiang, Mats Eriksson, Paolo Parini. J Lipid Res 2014
80
Embryonic fibroblasts from mice lacking Tgif were defective in cell cycling.
Lynn Mar, Pamela A Hoodless. Mol Cell Biol 2006
Lynn Mar, Pamela A Hoodless. Mol Cell Biol 2006
22
Suppression of TG-interacting factor sensitizes arsenic trioxide-induced apoptosis in human hepatocellular carcinoma cells.
Zi-Miao Liu, Joseph T Tseng, Duang-Yang Hong, Huei-Sheng Huang. Biochem J 2011
Zi-Miao Liu, Joseph T Tseng, Duang-Yang Hong, Huei-Sheng Huang. Biochem J 2011
19
Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling.
Y Shi, Y F Wang, L Jayaraman, H Yang, J Massagué, N P Pavletich. Cell 1998
Y Shi, Y F Wang, L Jayaraman, H Yang, J Massagué, N P Pavletich. Cell 1998
8
TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300.
R Janknecht, N J Wells, T Hunter. Genes Dev 1998
R Janknecht, N J Wells, T Hunter. Genes Dev 1998
8
Premature senescence and increased TGFβ signaling in the absence of Tgif1.
Brad J Zerlanko, Laurent Bartholin, Tiffany A Melhuish, David Wotton. PLoS One 2012
Brad J Zerlanko, Laurent Bartholin, Tiffany A Melhuish, David Wotton. PLoS One 2012
33
A poised chromatin platform for TGF-β access to master regulators.
Qiaoran Xi, Zhanxin Wang, Alexia-Ileana Zaromytidou, Xiang H-F Zhang, Lai-Fong Chow-Tsang, Jing X Liu, Hyesoo Kim, Afsar Barlas, Katia Manova-Todorova, Vesa Kaartinen,[...]. Cell 2011
Qiaoran Xi, Zhanxin Wang, Alexia-Ileana Zaromytidou, Xiang H-F Zhang, Lai-Fong Chow-Tsang, Jing X Liu, Hyesoo Kim, Afsar Barlas, Katia Manova-Todorova, Vesa Kaartinen,[...]. Cell 2011
7
A model of partnership co-opted by the homeodomain protein TGIF and the Itch/AIP4 ubiquitin ligase for effective execution of TNF-alpha cytotoxicity.
Christine Demange, Nathalie Ferrand, Céline Prunier, Marie-Francoise Bourgeade, Azeddine Atfi. Mol Cell 2009
Christine Demange, Nathalie Ferrand, Céline Prunier, Marie-Francoise Bourgeade, Azeddine Atfi. Mol Cell 2009
41
Expression and functional analysis of Tgif during mouse midline development.
Jiu-Zhen Jin, Shi Gu, Patrick McKinney, Jixiang Ding. Dev Dyn 2006
Jiu-Zhen Jin, Shi Gu, Patrick McKinney, Jixiang Ding. Dev Dyn 2006
24
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.