A citation-based method for searching scientific literature

S Artavanis-Tsakonas, M D Rand, R J Lake. Science 1999
Times Cited: 4562







List of co-cited articles
492 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



Notch Signaling in Development, Tissue Homeostasis, and Disease.
Chris Siebel, Urban Lendahl. Physiol Rev 2017
430
9

Notch signalling in context.
Sarah J Bray. Nat Rev Mol Cell Biol 2016
531
8

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
8

Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.
Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, Freddie Bray. CA Cancer J Clin 2021
8

The Varied Roles of Notch in Cancer.
Jon C Aster, Warren S Pear, Stephen C Blacklow. Annu Rev Pathol 2017
337
8

Notch signalling: a simple pathway becomes complex.
Sarah J Bray. Nat Rev Mol Cell Biol 2006
7

Cis-interactions between Notch and Delta generate mutually exclusive signalling states.
David Sprinzak, Amit Lakhanpal, Lauren Lebon, Leah A Santat, Michelle E Fontes, Graham A Anderson, Jordi Garcia-Ojalvo, Michael B Elowitz. Nature 2010
396
7

The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis.
Rui Benedito, Cristina Roca, Inga Sörensen, Susanne Adams, Achim Gossler, Marcus Fruttiger, Ralf H Adams. Cell 2009
723
7


Notch signalling in vertebrate neural development.
Angeliki Louvi, Spyros Artavanis-Tsakonas. Nat Rev Neurosci 2006
665
6

Mechanism and significance of cis-inhibition in Notch signalling.
David del Álamo, Hervé Rouault, François Schweisguth. Curr Biol 2011
175
5

The Notch signalling system: recent insights into the complexity of a conserved pathway.
K G Guruharsha, Mark W Kankel, Spyros Artavanis-Tsakonas. Nat Rev Genet 2012
483
5

Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development.
Frances A High, Min Min Lu, Warren S Pear, Kathleen M Loomes, Klaus H Kaestner, Jonathan A Epstein. Proc Natl Acad Sci U S A 2008
228
5

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.
Mats Hellström, Li-Kun Phng, Jennifer J Hofmann, Elisabet Wallgard, Leigh Coultas, Per Lindblom, Jackelyn Alva, Ann-Katrin Nilsson, Linda Karlsson, Nicholas Gaiano,[...]. Nature 2007
5

NOTCH1 is a mechanosensor in adult arteries.
Julia J Mack, Thiago S Mosqueiro, Brian J Archer, William M Jones, Hannah Sunshine, Guido C Faas, Anais Briot, Raquel L Aragón, Trent Su, Milagros C Romay,[...]. Nat Commun 2017
134
5

First-in-human study of LY3039478, an oral Notch signaling inhibitor in advanced or metastatic cancer.
C Massard, A Azaro, J-C Soria, U Lassen, C Le Tourneau, D Sarker, C Smith, U Ohnmacht, G Oakley, B K R Patel,[...]. Ann Oncol 2018
78
6

Notch signaling: simplicity in design, versatility in function.
Emma R Andersson, Rickard Sandberg, Urban Lendahl. Development 2011
657
4



Mutual inactivation of Notch receptors and ligands facilitates developmental patterning.
David Sprinzak, Amit Lakhanpal, Lauren LeBon, Jordi Garcia-Ojalvo, Michael B Elowitz. PLoS Comput Biol 2011
82
4


Cis-activation in the Notch signaling pathway.
Nagarajan Nandagopal, Leah A Santat, Michael B Elowitz. Elife 2019
42
9

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1.
J S Mumm, E H Schroeter, M T Saxena, A Griesemer, X Tian, D J Pan, W J Ray, R Kopan. Mol Cell 2000
661
4

γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct.
Yong Ran, Fokhrul Hossain, Antonio Pannuti, Christian B Lessard, Gabriela Z Ladd, Joo In Jung, Lisa M Minter, Barbara A Osborne, Lucio Miele, Todd E Golde. EMBO Mol Med 2017
88
4

A Phase I, dose-finding study in patients with advanced solid malignancies of the oral γ-secretase inhibitor PF-03084014.
Wells A Messersmith, Geoffrey I Shapiro, James M Cleary, Antonio Jimeno, Arvind Dasari, Bo Huang, M Naveed Shaik, Rossano Cesari, Xianxian Zheng, Jennifer M Reynolds,[...]. Clin Cancer Res 2015
139
4

Notch signaling: an emerging therapeutic target for cancer treatment.
Xun Yuan, Hua Wu, Hanxiao Xu, Huihua Xiong, Qian Chu, Shiying Yu, Gen Sheng Wu, Kongming Wu. Cancer Lett 2015
254
4

Structural basis for autoinhibition of Notch.
Wendy R Gordon, Didem Vardar-Ulu, Gavin Histen, Cheryll Sanchez-Irizarry, Jon C Aster, Stephen C Blacklow. Nat Struct Mol Biol 2007
243
4

Notch signaling determines the M1 versus M2 polarization of macrophages in antitumor immune responses.
Yao-Chun Wang, Fei He, Fan Feng, Xiao-Wei Liu, Guang-Ying Dong, Hong-Yan Qin, Xing-Bin Hu, Min-Hua Zheng, Liang Liang, Lei Feng,[...]. Cancer Res 2010
302
4

Notch and cancer: a double-edged sword.
U Koch, F Radtke. Cell Mol Life Sci 2007
261
4

The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force.
Rhett A Kovall, Brian Gebelein, David Sprinzak, Raphael Kopan. Dev Cell 2017
191
4

Notch signalling controls pancreatic cell differentiation.
A Apelqvist, H Li, L Sommer, P Beatus, D J Anderson, T Honjo, M Hrabe de Angelis, U Lendahl, H Edlund. Nature 1999
921
4

The many facets of Notch ligands.
B D'Souza, A Miyamoto, G Weinmaster. Oncogene 2008
326
4

Notch signaling in cancer.
Eric J Allenspach, Ivan Maillard, Jon C Aster, Warren S Pear. Cancer Biol Ther 2002
244
4

The roles of receptor and ligand endocytosis in regulating Notch signaling.
Roland Le Borgne, Allison Bardin, François Schweisguth. Development 2005
254
3

Notch signaling.
S Artavanis-Tsakonas, K Matsuno, M E Fortini. Science 1995
3

AIP4/Itch regulates Notch receptor degradation in the absence of ligand.
Patricia Chastagner, Alain Israël, Christel Brou. PLoS One 2008
104
3

Numb regulates post-endocytic trafficking and degradation of Notch1.
Melanie A McGill, Sascha E Dho, Gerry Weinmaster, C Jane McGlade. J Biol Chem 2009
162
3

Notch targets and their regulation.
Sarah Bray, Fred Bernard. Curr Top Dev Biol 2010
124
3


Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation.
Tadashi Sakata, Hiromi Sakaguchi, Leo Tsuda, Atsushi Higashitani, Toshiro Aigaki, Kenji Matsuno, Shigeo Hayashi. Curr Biol 2004
149
3




A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE.
C Brou, F Logeat, N Gupta, C Bessia, O LeBail, J R Doedens, A Cumano, P Roux, R A Black, A Israël. Mol Cell 2000
848
3







Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.