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Times Cited: 367
Times Cited: 367
Times Cited
Times Co-cited
Similarity
TAM receptors are pleiotropic inhibitors of the innate immune response.
Carla V Rothlin, Sourav Ghosh, Elina I Zuniga, Michael B A Oldstone, Greg Lemke. Cell 2007
Carla V Rothlin, Sourav Ghosh, Elina I Zuniga, Michael B A Oldstone, Greg Lemke. Cell 2007
48
Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family.
Q Lu, G Lemke. Science 2001
Q Lu, G Lemke. Science 2001
39
Diversification of TAM receptor tyrosine kinase function.
Anna Zagórska, Paqui G Través, Erin D Lew, Ian Dransfield, Greg Lemke. Nat Immunol 2014
Anna Zagórska, Paqui G Través, Erin D Lew, Ian Dransfield, Greg Lemke. Nat Immunol 2014
39
Phagocytosis and clearance of apoptotic cells is mediated by MER.
R S Scott, E J McMahon, S M Pop, E A Reap, R Caricchio, P L Cohen, H S Earp, G K Matsushima. Nature 2001
R S Scott, E J McMahon, S M Pop, E A Reap, R Caricchio, P L Cohen, H S Earp, G K Matsushima. Nature 2001
35
Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities.
Erin D Lew, Jennifer Oh, Patrick G Burrola, Irit Lax, Anna Zagórska, Paqui G Través, Joseph Schlessinger, Greg Lemke. Elife 2014
Erin D Lew, Jennifer Oh, Patrick G Burrola, Irit Lax, Anna Zagórska, Paqui G Través, Joseph Schlessinger, Greg Lemke. Elife 2014
35
Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells.
Heather M Seitz, Todd D Camenisch, Greg Lemke, H Shelton Earp, Glenn K Matsushima. J Immunol 2007
Heather M Seitz, Todd D Camenisch, Greg Lemke, H Shelton Earp, Glenn K Matsushima. J Immunol 2007
30
TAM receptor signaling in immune homeostasis.
Carla V Rothlin, Eugenio A Carrera-Silva, Lidia Bosurgi, Sourav Ghosh. Annu Rev Immunol 2015
Carla V Rothlin, Eugenio A Carrera-Silva, Lidia Bosurgi, Sourav Ghosh. Annu Rev Immunol 2015
29
TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer.
Rachel M A Linger, Amy K Keating, H Shelton Earp, Douglas K Graham. Adv Cancer Res 2008
Rachel M A Linger, Amy K Keating, H Shelton Earp, Douglas K Graham. Adv Cancer Res 2008
27
The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases.
T N Stitt, G Conn, M Gore, C Lai, J Bruno, C Radziejewski, K Mattsson, J Fisher, D R Gies, P F Jones. Cell 1995
T N Stitt, G Conn, M Gore, C Lai, J Bruno, C Radziejewski, K Mattsson, J Fisher, D R Gies, P F Jones. Cell 1995
26
TAM receptor function in the retinal pigment epithelium.
Dipti Prasad, Carla Vanina Rothlin, Patrick Burrola, Tal Burstyn-Cohen, Qingxian Lu, Pablo Garcia de Frutos, Greg Lemke. Mol Cell Neurosci 2006
Dipti Prasad, Carla Vanina Rothlin, Patrick Burrola, Tal Burstyn-Cohen, Qingxian Lu, Pablo Garcia de Frutos, Greg Lemke. Mol Cell Neurosci 2006
25
The TAM family: phosphatidylserine sensing receptor tyrosine kinases gone awry in cancer.
Douglas K Graham, Deborah DeRyckere, Kurtis D Davies, H Shelton Earp. Nat Rev Cancer 2014
Douglas K Graham, Deborah DeRyckere, Kurtis D Davies, H Shelton Earp. Nat Rev Cancer 2014
24
Receptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activation.
Wen-I Tsou, Khanh-Quynh N Nguyen, Daniel A Calarese, Scott J Garforth, Anita L Antes, Sergey V Smirnov, Steve C Almo, Raymond B Birge, Sergei V Kotenko. J Biol Chem 2014
Wen-I Tsou, Khanh-Quynh N Nguyen, Daniel A Calarese, Scott J Garforth, Anita L Antes, Sergey V Smirnov, Steve C Almo, Raymond B Birge, Sergei V Kotenko. J Biol Chem 2014
24
Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases.
K Nagata, K Ohashi, T Nakano, H Arita, C Zong, H Hanafusa, K Mizuno. J Biol Chem 1996
K Nagata, K Ohashi, T Nakano, H Arita, C Zong, H Hanafusa, K Mizuno. J Biol Chem 1996
22
Genetic dissection of TAM receptor-ligand interaction in retinal pigment epithelial cell phagocytosis.
Tal Burstyn-Cohen, Erin D Lew, Paqui G Través, Patrick G Burrola, Joseph C Hash, Greg Lemke. Neuron 2012
Tal Burstyn-Cohen, Erin D Lew, Paqui G Través, Patrick G Burrola, Joseph C Hash, Greg Lemke. Neuron 2012
21
TAM receptors regulate multiple features of microglial physiology.
Lawrence Fourgeaud, Paqui G Través, Yusuf Tufail, Humberto Leal-Bailey, Erin D Lew, Patrick G Burrola, Perri Callaway, Anna Zagórska, Carla V Rothlin, Axel Nimmerjahn,[...]. Nature 2016
Lawrence Fourgeaud, Paqui G Través, Yusuf Tufail, Humberto Leal-Bailey, Erin D Lew, Patrick G Burrola, Perri Callaway, Anna Zagórska, Carla V Rothlin, Axel Nimmerjahn,[...]. Nature 2016
20
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells.
Magdalena Paolino, Axel Choidas, Stephanie Wallner, Blanka Pranjic, Iris Uribesalgo, Stefanie Loeser, Amanda M Jamieson, Wallace Y Langdon, Fumiyo Ikeda, Juan Pablo Fededa,[...]. Nature 2014
Magdalena Paolino, Axel Choidas, Stephanie Wallner, Blanka Pranjic, Iris Uribesalgo, Stefanie Loeser, Amanda M Jamieson, Wallace Y Langdon, Fumiyo Ikeda, Juan Pablo Fededa,[...]. Nature 2014
20
axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.
J P O'Bryan, R A Frye, P C Cogswell, A Neubauer, B Kitch, C Prokop, R Espinosa, M M Le Beau, H S Earp, E T Liu. Mol Cell Biol 1991
J P O'Bryan, R A Frye, P C Cogswell, A Neubauer, B Kitch, C Prokop, R Espinosa, M M Le Beau, H S Earp, E T Liu. Mol Cell Biol 1991
19
A novel receptor tyrosine kinase, Mer, inhibits TNF-alpha production and lipopolysaccharide-induced endotoxic shock.
T D Camenisch, B H Koller, H S Earp, G K Matsushima. J Immunol 1999
T D Camenisch, B H Koller, H S Earp, G K Matsushima. J Immunol 1999
18
Cloning and mRNA expression analysis of a novel human protooncogene, c-mer.
D K Graham, T L Dawson, D L Mullaney, H R Snodgrass, H S Earp. Cell Growth Differ 1994
D K Graham, T L Dawson, D L Mullaney, H R Snodgrass, H S Earp. Cell Growth Differ 1994
18
Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase.
Philip L Cohen, Roberto Caricchio, Valsamma Abraham, Todd D Camenisch, J Charles Jennette, Robert A S Roubey, H Shelton Earp, Glenn Matsushima, Elizabeth A Reap. J Exp Med 2002
Philip L Cohen, Roberto Caricchio, Valsamma Abraham, Todd D Camenisch, J Charles Jennette, Robert A S Roubey, H Shelton Earp, Glenn Matsushima, Elizabeth A Reap. J Exp Med 2002
18
TAM receptors and the clearance of apoptotic cells.
Greg Lemke, Tal Burstyn-Cohen. Ann N Y Acad Sci 2010
Greg Lemke, Tal Burstyn-Cohen. Ann N Y Acad Sci 2010
18
An RCS-like retinal dystrophy phenotype in mer knockout mice.
Jacque L Duncan, Matthew M LaVail, Douglas Yasumura, Michael T Matthes, Haidong Yang, Nikolaus Trautmann, Aimee V Chappelow, Wei Feng, H Shelton Earp, Glenn K Matsushima,[...]. Invest Ophthalmol Vis Sci 2003
Jacque L Duncan, Matthew M LaVail, Douglas Yasumura, Michael T Matthes, Haidong Yang, Nikolaus Trautmann, Aimee V Chappelow, Wei Feng, H Shelton Earp, Glenn K Matsushima,[...]. Invest Ophthalmol Vis Sci 2003
18
A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation.
Susan Sather, Karla D Kenyon, Jerry B Lefkowitz, Xiayuan Liang, Brian C Varnum, Peter M Henson, Douglas K Graham. Blood 2007
Susan Sather, Karla D Kenyon, Jerry B Lefkowitz, Xiayuan Liang, Brian C Varnum, Peter M Henson, Douglas K Graham. Blood 2007
17
T cell-derived protein S engages TAM receptor signaling in dendritic cells to control the magnitude of the immune response.
Eugenio A Carrera Silva, Pamela Y Chan, Leonel Joannas, Andrea E Errasti, Nicola Gagliani, Lidia Bosurgi, Maurice Jabbour, Anthony Perry, Faye Smith-Chakmakova, Daniel Mucida,[...]. Immunity 2013
Eugenio A Carrera Silva, Pamela Y Chan, Leonel Joannas, Andrea E Errasti, Nicola Gagliani, Lidia Bosurgi, Maurice Jabbour, Anthony Perry, Faye Smith-Chakmakova, Daniel Mucida,[...]. Immunity 2013
17
Phagocytosis of apoptotic cells in homeostasis.
Sanja Arandjelovic, Kodi S Ravichandran. Nat Immunol 2015
Sanja Arandjelovic, Kodi S Ravichandran. Nat Immunol 2015
16
Tubby and tubby-like protein 1 are new MerTK ligands for phagocytosis.
Nora B Caberoy, Yixiong Zhou, Wei Li. EMBO J 2010
Nora B Caberoy, Yixiong Zhou, Wei Li. EMBO J 2010
16
Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat.
P M D'Cruz, D Yasumura, J Weir, M T Matthes, H Abderrahim, M M LaVail, D Vollrath. Hum Mol Genet 2000
P M D'Cruz, D Yasumura, J Weir, M T Matthes, H Abderrahim, M M LaVail, D Vollrath. Hum Mol Genet 2000
16
Galectin-3 is a new MerTK-specific eat-me signal.
Nora B Caberoy, Gabriela Alvarado, Jo-Lawrence Bigcas, Wei Li. J Cell Physiol 2012
Nora B Caberoy, Gabriela Alvarado, Jo-Lawrence Bigcas, Wei Li. J Cell Physiol 2012
15
TNF-alpha, IL-6, and IL-1 expression is inhibited by GAS6 in monocytes/macrophages.
Federica Alciato, Pier Paolo Sainaghi, Daniele Sola, Luigi Castello, Gian Carlo Avanzi. J Leukoc Biol 2010
Federica Alciato, Pier Paolo Sainaghi, Daniele Sola, Luigi Castello, Gian Carlo Avanzi. J Leukoc Biol 2010
14
R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer.
Sacha J Holland, Alison Pan, Christian Franci, Yuanming Hu, Betty Chang, Weiqun Li, Matt Duan, Allan Torneros, Jiaxin Yu, Thilo J Heckrodt,[...]. Cancer Res 2010
Sacha J Holland, Alison Pan, Christian Franci, Yuanming Hu, Betty Chang, Weiqun Li, Matt Duan, Allan Torneros, Jiaxin Yu, Thilo J Heckrodt,[...]. Cancer Res 2010
14
Efficient clearance of early apoptotic cells by human macrophages requires M2c polarization and MerTK induction.
Gaetano Zizzo, Brendan A Hilliard, Marc Monestier, Philip L Cohen. J Immunol 2012
Gaetano Zizzo, Brendan A Hilliard, Marc Monestier, Philip L Cohen. J Immunol 2012
14
Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa.
A Gal, Y Li, D A Thompson, J Weir, U Orth, S G Jacobson, E Apfelstedt-Sylla, D Vollrath. Nat Genet 2000
A Gal, Y Li, D A Thompson, J Weir, U Orth, S G Jacobson, E Apfelstedt-Sylla, D Vollrath. Nat Genet 2000
14
Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis.
A Angelillo-Scherrer, P de Frutos, C Aparicio, E Melis, P Savi, F Lupu, J Arnout, M Dewerchin, M Hoylaerts, J Herbert,[...]. Nat Med 2001
A Angelillo-Scherrer, P de Frutos, C Aparicio, E Melis, P Savi, F Lupu, J Arnout, M Dewerchin, M Hoylaerts, J Herbert,[...]. Nat Med 2001
14
MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation.
Bishuang Cai, Edward B Thorp, Amanda C Doran, Manikandan Subramanian, Brian E Sansbury, Chyuan-Sheng Lin, Matthew Spite, Gabrielle Fredman, Ira Tabas. Proc Natl Acad Sci U S A 2016
Bishuang Cai, Edward B Thorp, Amanda C Doran, Manikandan Subramanian, Brian E Sansbury, Chyuan-Sheng Lin, Matthew Spite, Gabrielle Fredman, Ira Tabas. Proc Natl Acad Sci U S A 2016
13
13
Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression.
Canan Kasikara, Sushil Kumar, Stanley Kimani, Wen-I Tsou, Ke Geng, Viralkumar Davra, Ganapathy Sriram, Connor Devoe, Khanh-Quynh N Nguyen, Anita Antes,[...]. Mol Cancer Res 2017
Canan Kasikara, Sushil Kumar, Stanley Kimani, Wen-I Tsou, Ke Geng, Viralkumar Davra, Ganapathy Sriram, Connor Devoe, Khanh-Quynh N Nguyen, Anita Antes,[...]. Mol Cancer Res 2017
17
MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis.
Bishuang Cai, Edward B Thorp, Amanda C Doran, Brian E Sansbury, Mat J A P Daemen, Bernhard Dorweiler, Matthew Spite, Gabrielle Fredman, Ira Tabas. J Clin Invest 2017
Bishuang Cai, Edward B Thorp, Amanda C Doran, Brian E Sansbury, Mat J A P Daemen, Bernhard Dorweiler, Matthew Spite, Gabrielle Fredman, Ira Tabas. J Clin Invest 2017
12
Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 mitogen-activated protein kinase (MAPK).
Edward Thorp, Tomas Vaisar, Manikandan Subramanian, Lauren Mautner, Carl Blobel, Ira Tabas. J Biol Chem 2011
Edward Thorp, Tomas Vaisar, Manikandan Subramanian, Lauren Mautner, Carl Blobel, Ira Tabas. J Biol Chem 2011
12
TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis.
Jonathan H M van der Meer, Tom van der Poll, Cornelis van 't Veer. Blood 2014
Jonathan H M van der Meer, Tom van der Poll, Cornelis van 't Veer. Blood 2014
12
An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system.
C Lai, G Lemke. Neuron 1991
C Lai, G Lemke. Neuron 1991
12
MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis.
Rebecca S Cook, Kristen M Jacobsen, Anne M Wofford, Deborah DeRyckere, Jamie Stanford, Anne L Prieto, Elizabeth Redente, Melissa Sandahl, Debra M Hunter, Karen E Strunk,[...]. J Clin Invest 2013
Rebecca S Cook, Kristen M Jacobsen, Anne M Wofford, Deborah DeRyckere, Jamie Stanford, Anne L Prieto, Elizabeth Redente, Melissa Sandahl, Debra M Hunter, Karen E Strunk,[...]. J Clin Invest 2013
12
Enveloped viruses disable innate immune responses in dendritic cells by direct activation of TAM receptors.
Suchita Bhattacharyya, Anna Zagórska, Erin D Lew, Bimmi Shrestha, Carla V Rothlin, John Naughton, Michael S Diamond, Greg Lemke, John A T Young. Cell Host Microbe 2013
Suchita Bhattacharyya, Anna Zagórska, Erin D Lew, Bimmi Shrestha, Carla V Rothlin, John Naughton, Michael S Diamond, Greg Lemke, John A T Young. Cell Host Microbe 2013
11
Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during experimental autoimmune encephalomyelitis.
Jason G Weinger, Celia F Brosnan, Olivier Loudig, Michael F Goldberg, Fernando Macian, Heather A Arnett, Anne L Prieto, Vladislav Tsiperson, Bridget Shafit-Zagardo. J Neuroinflammation 2011
Jason G Weinger, Celia F Brosnan, Olivier Loudig, Michael F Goldberg, Fernando Macian, Heather A Arnett, Anne L Prieto, Vladislav Tsiperson, Bridget Shafit-Zagardo. J Neuroinflammation 2011
14
The mer receptor tyrosine kinase: expression and function suggest a role in innate immunity.
Edward M Behrens, Paul Gadue, Shun-you Gong, Stacey Garrett, Paul L Stein, Philip L Cohen. Eur J Immunol 2003
Edward M Behrens, Paul Gadue, Shun-you Gong, Stacey Garrett, Paul L Stein, Philip L Cohen. Eur J Immunol 2003
13
Gas6 and protein S. Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily.
Sassan Hafizi, Björn Dahlbäck. FEBS J 2006
Sassan Hafizi, Björn Dahlbäck. FEBS J 2006
11
Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways.
Won-Suk Chung, Laura E Clarke, Gordon X Wang, Benjamin K Stafford, Alexander Sher, Chandrani Chakraborty, Julia Joung, Lynette C Foo, Andrew Thompson, Chinfei Chen,[...]. Nature 2013
Won-Suk Chung, Laura E Clarke, Gordon X Wang, Benjamin K Stafford, Alexander Sher, Chandrani Chakraborty, Julia Joung, Lynette C Foo, Andrew Thompson, Chinfei Chen,[...]. Nature 2013
11
Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6.
Sonja Loges, Thomas Schmidt, Marc Tjwa, Katie van Geyte, Dirk Lievens, Esther Lutgens, Davy Vanhoutte, Delphine Borgel, Stephane Plaisance, Marc Hoylaerts,[...]. Blood 2010
Sonja Loges, Thomas Schmidt, Marc Tjwa, Katie van Geyte, Dirk Lievens, Esther Lutgens, Davy Vanhoutte, Delphine Borgel, Stephane Plaisance, Marc Hoylaerts,[...]. Blood 2010
11
UNC2025, a potent and orally bioavailable MER/FLT3 dual inhibitor.
Weihe Zhang, Deborah DeRyckere, Debra Hunter, Jing Liu, Michael A Stashko, Katherine A Minson, Christopher T Cummings, Minjung Lee, Trevor G Glaros, Dianne L Newton,[...]. J Med Chem 2014
Weihe Zhang, Deborah DeRyckere, Debra Hunter, Jing Liu, Michael A Stashko, Katherine A Minson, Christopher T Cummings, Minjung Lee, Trevor G Glaros, Dianne L Newton,[...]. J Med Chem 2014
12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.