S Ragusa, P Mouchet, C Lazennec, V Dive, T Meinnel. J Mol Biol 1999
Times Cited: 52
Times Cited: 52
Times Cited
Times Co-cited
Similarity
Genetic characterization of polypeptide deformylase, a distinctive enzyme of eubacterial translation.
D Mazel, S Pochet, P Marlière. EMBO J 1994
D Mazel, S Pochet, P Marlière. EMBO J 1994
57
Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor.
D Z Chen, D V Patel, C J Hackbarth, W Wang, G Dreyer, D C Young, P S Margolis, C Wu, Z J Ni, J Trias,[...]. Biochemistry 2000
D Z Chen, D V Patel, C J Hackbarth, W Wang, G Dreyer, D C Young, P S Margolis, C Wu, Z J Ni, J Trias,[...]. Biochemistry 2000
55
Control of peptide deformylase activity by metal cations.
S Ragusa, S Blanquet, T Meinnel. J Mol Biol 1998
S Ragusa, S Blanquet, T Meinnel. J Mol Biol 1998
51
Iron center, substrate recognition and mechanism of peptide deformylase.
A Becker, I Schlichting, W Kabsch, D Groche, S Schultz, A F Wagner. Nat Struct Biol 1998
A Becker, I Schlichting, W Kabsch, D Groche, S Schultz, A F Wagner. Nat Struct Biol 1998
48
Crystal structure of the Escherichia coli peptide deformylase.
M K Chan, W Gong, P T Rajagopalan, B Hao, C M Tsai, D Pei. Biochemistry 1997
M K Chan, W Gong, P T Rajagopalan, B Hao, C M Tsai, D Pei. Biochemistry 1997
46
Solution structure of nickel-peptide deformylase.
F Dardel, S Ragusa, C Lazennec, S Blanquet, T Meinnel. J Mol Biol 1998
F Dardel, S Ragusa, C Lazennec, S Blanquet, T Meinnel. J Mol Biol 1998
46
Characterization of cobalt(II)-substituted peptide deformylase: function of the metal ion and the catalytic residue Glu-133.
P T Rajagopalan, S Grimme, D Pei. Biochemistry 2000
P T Rajagopalan, S Grimme, D Pei. Biochemistry 2000
44
Antibiotic activity and characterization of BB-3497, a novel peptide deformylase inhibitor.
J M Clements, R P Beckett, A Brown, G Catlin, M Lobell, S Palan, W Thomas, M Whittaker, S Wood, S Salama,[...]. Antimicrob Agents Chemother 2001
J M Clements, R P Beckett, A Brown, G Catlin, M Lobell, S Palan, W Thomas, M Whittaker, S Wood, S Salama,[...]. Antimicrob Agents Chemother 2001
44
Structure-function relationships within the peptide deformylase family. Evidence for a conserved architecture of the active site involving three conserved motifs and a metal ion.
T Meinnel, C Lazennec, S Villoing, S Blanquet. J Mol Biol 1997
T Meinnel, C Lazennec, S Villoing, S Blanquet. J Mol Biol 1997
42
Isolation and crystallization of functionally competent Escherichia coli peptide deformylase forms containing either iron or nickel in the active site.
D Groche, A Becker, I Schlichting, W Kabsch, S Schultz, A F Wagner. Biochem Biophys Res Commun 1998
D Groche, A Becker, I Schlichting, W Kabsch, S Schultz, A F Wagner. Biochem Biophys Res Commun 1998
42
Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms.
C Giglione, A Serero, M Pierre, B Boisson, T Meinnel. EMBO J 2000
C Giglione, A Serero, M Pierre, B Boisson, T Meinnel. EMBO J 2000
42
A new subclass of the zinc metalloproteases superfamily revealed by the solution structure of peptide deformylase.
T Meinnel, S Blanquet, F Dardel. J Mol Biol 1996
T Meinnel, S Blanquet, F Dardel. J Mol Biol 1996
40
Design and synthesis of substrate analogue inhibitors of peptide deformylase.
T Meinnel, L Patiny, S Ragusa, S Blanquet. Biochemistry 1999
T Meinnel, L Patiny, S Ragusa, S Blanquet. Biochemistry 1999
40
Peptide deformylase as a target for new generation, broad spectrum antimicrobial agents.
C Giglione, M Pierre, T Meinnel. Mol Microbiol 2000
C Giglione, M Pierre, T Meinnel. Mol Microbiol 2000
38
Structure of peptide deformylase and identification of the substrate binding site.
A Becker, I Schlichting, W Kabsch, S Schultz, A F Wagner. J Biol Chem 1998
A Becker, I Schlichting, W Kabsch, S Schultz, A F Wagner. J Biol Chem 1998
36
Characterization of the Thermus thermophilus locus encoding peptide deformylase and methionyl-tRNA(fMet) formyltransferase.
T Meinnel, S Blanquet. J Bacteriol 1994
T Meinnel, S Blanquet. J Bacteriol 1994
36
Distinctive features of the two classes of eukaryotic peptide deformylases.
A Serero, C Giglione, T Meinnel. J Mol Biol 2001
A Serero, C Giglione, T Meinnel. J Mol Biol 2001
36
Structural basis for the design of antibiotics targeting peptide deformylase.
B Hao, W Gong, P T Rajagopalan, Y Zhou, D Pei, M K Chan. Biochemistry 1999
B Hao, W Gong, P T Rajagopalan, Y Zhou, D Pei, M K Chan. Biochemistry 1999
32
Purification, characterization, and inhibition of peptide deformylase from Escherichia coli.
P T Rajagopalan, A Datta, D Pei. Biochemistry 1997
P T Rajagopalan, A Datta, D Pei. Biochemistry 1997
32
Formate dehydrogenase-coupled spectrophotometric assay of peptide deformylase.
C Lazennec, T Meinnel. Anal Biochem 1997
C Lazennec, T Meinnel. Anal Biochem 1997
32
Mapping of the active site zinc ligands of peptide deformylase.
T Meinnel, C Lazennec, S Blanquet. J Mol Biol 1995
T Meinnel, C Lazennec, S Blanquet. J Mol Biol 1995
32
Enzymatic properties of Escherichia coli peptide deformylase.
T Meinnel, S Blanquet. J Bacteriol 1995
T Meinnel, S Blanquet. J Bacteriol 1995
32
Peptide deformylase of eukaryotic protists: a target for new antiparasitic agents?
T Meinnel. Parasitol Today 2000
T Meinnel. Parasitol Today 2000
31
Methionine as translation start signal: a review of the enzymes of the pathway in Escherichia coli.
T Meinnel, Y Mechulam, S Blanquet. Biochimie 1993
T Meinnel, Y Mechulam, S Blanquet. Biochimie 1993
28
The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: a platform for the structure-based design of antibacterial agents.
Jean-Pierre Guilloteau, Magali Mathieu, Carmela Giglione, Véronique Blanc, Alain Dupuy, Miline Chevrier, Patricia Gil, Alain Famechon, Thierry Meinnel, Vincent Mikol. J Mol Biol 2002
Jean-Pierre Guilloteau, Magali Mathieu, Carmela Giglione, Véronique Blanc, Alain Dupuy, Miline Chevrier, Patricia Gil, Alain Famechon, Thierry Meinnel, Vincent Mikol. J Mol Biol 2002
28
Determination of substrate specificity for peptide deformylase through the screening of a combinatorial peptide library.
Y J Hu, Y Wei, Y Zhou, P T Rajagopalan, D Pei. Biochemistry 1999
Y J Hu, Y Wei, Y Zhou, P T Rajagopalan, D Pei. Biochemistry 1999
26
Synthesis and antibacterial activity of peptide deformylase inhibitors.
K M Huntington, T Yi, Y Wei, D Pei. Biochemistry 2000
K M Huntington, T Yi, Y Wei, D Pei. Biochemistry 2000
26
Characterization of a human peptide deformylase: implications for antibacterial drug design.
Kiet T Nguyen, Xubo Hu, Craig Colton, Ratna Chakrabarti, Michael X Zhu, Dehua Pei. Biochemistry 2003
Kiet T Nguyen, Xubo Hu, Craig Colton, Ratna Chakrabarti, Michael X Zhu, Dehua Pei. Biochemistry 2003
26
An unusual peptide deformylase features in the human mitochondrial N-terminal methionine excision pathway.
Alexandre Serero, Carmela Giglione, Alessandro Sardini, Juan Martinez-Sanz, Thierry Meinnel. J Biol Chem 2003
Alexandre Serero, Carmela Giglione, Alessandro Sardini, Juan Martinez-Sanz, Thierry Meinnel. J Biol Chem 2003
26
25
36
Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents.
C Apfel, D W Banner, D Bur, M Dietz, T Hirata, C Hubschwerlen, H Locher, M G Page, W Pirson, G Rossé,[...]. J Med Chem 2000
C Apfel, D W Banner, D Bur, M Dietz, T Hirata, C Hubschwerlen, H Locher, M G Page, W Pirson, G Rossé,[...]. J Med Chem 2000
25
Control of protein life-span by N-terminal methionine excision.
Carmela Giglione, Olivier Vallon, Thierry Meinnel. EMBO J 2003
Carmela Giglione, Olivier Vallon, Thierry Meinnel. EMBO J 2003
25
25
The C-terminal domain of peptide deformylase is disordered and dispensable for activity.
T Meinnel, C Lazennec, F Dardel, J M Schmitter, S Blanquet. FEBS Lett 1996
T Meinnel, C Lazennec, F Dardel, J M Schmitter, S Blanquet. FEBS Lett 1996
30
Processing of the N termini of nascent polypeptide chains requires deformylation prior to methionine removal.
J Solbiati, A Chapman-Smith, J L Miller, C G Miller, J E Cronan. J Mol Biol 1999
J Solbiati, A Chapman-Smith, J L Miller, C G Miller, J E Cronan. J Mol Biol 1999
23
Organellar peptide deformylases: universality of the N-terminal methionine cleavage mechanism.
C Giglione, T Meinnel. Trends Plant Sci 2001
C Giglione, T Meinnel. Trends Plant Sci 2001
23
Inhibition of bacterial peptide deformylase by biaryl acid analogs.
B G Green, J H Toney, J W Kozarich, S K Grant. Arch Biochem Biophys 2000
B G Green, J H Toney, J W Kozarich, S K Grant. Arch Biochem Biophys 2000
32
Peptide deformylase in Staphylococcus aureus: resistance to inhibition is mediated by mutations in the formyltransferase gene.
P S Margolis, C J Hackbarth, D C Young, W Wang, D Chen, Z Yuan, R White, J Trias. Antimicrob Agents Chemother 2000
P S Margolis, C J Hackbarth, D C Young, W Wang, D Chen, Z Yuan, R White, J Trias. Antimicrob Agents Chemother 2000
21
21
Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics.
Mona D Lee, Yuhong She, Michael J Soskis, Christopher P Borella, Jeffrey R Gardner, Paula A Hayes, Benzon M Dy, Mark L Heaney, Mark R Philips, William G Bornmann,[...]. J Clin Invest 2004
Mona D Lee, Yuhong She, Michael J Soskis, Christopher P Borella, Jeffrey R Gardner, Paula A Hayes, Benzon M Dy, Mark L Heaney, Mark R Philips, William G Bornmann,[...]. J Clin Invest 2004
21
Peptide aldehyde inhibitors of bacterial peptide deformylases.
D J Durand, B Gordon Green, J F O'Connell, S K Grant. Arch Biochem Biophys 1999
D J Durand, B Gordon Green, J F O'Connell, S K Grant. Arch Biochem Biophys 1999
33
A survey of polypeptide deformylase function throughout the eubacterial lineage.
D Mazel, E Coïc, S Blanchard, W Saurin, P Marlière. J Mol Biol 1997
D Mazel, E Coïc, S Blanchard, W Saurin, P Marlière. J Mol Biol 1997
20
The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms.
Sonia Fieulaine, Céline Juillan-Binard, Alexandre Serero, Frédéric Dardel, Carmela Giglione, Thierry Meinnel, Jean-Luc Ferrer. J Biol Chem 2005
Sonia Fieulaine, Céline Juillan-Binard, Alexandre Serero, Frédéric Dardel, Carmela Giglione, Thierry Meinnel, Jean-Luc Ferrer. J Biol Chem 2005
29
Antitumor activity of actinonin in vitro and in vivo.
Y Xu, L T Lai, J L Gabrilove, D A Scheinberg. Clin Cancer Res 1998
Y Xu, L T Lai, J L Gabrilove, D A Scheinberg. Clin Cancer Res 1998
18
Novel nonpeptidic inhibitors of peptide deformylase.
M M Jayasekera, A Kendall, R Shammas, M Dermyer, M Tomala, M A Shapiro, T P Holler. Arch Biochem Biophys 2000
M M Jayasekera, A Kendall, R Shammas, M Dermyer, M Tomala, M A Shapiro, T P Holler. Arch Biochem Biophys 2000
34
A new human peptide deformylase inhibitable by actinonin.
Mona D Lee, Christophe Antczak, Yueming Li, Francis M Sirotnak, William G Bornmann, David A Scheinberg. Biochem Biophys Res Commun 2003
Mona D Lee, Christophe Antczak, Yueming Li, Francis M Sirotnak, William G Bornmann, David A Scheinberg. Biochem Biophys Res Commun 2003
20
Discovery and refinement of a new structural class of potent peptide deformylase inhibitors.
Adrien Boularot, Carmela Giglione, Sylvain Petit, Yann Duroc, Rodolphe Alves de Sousa, Valéry Larue, Thierry Cresteil, Frédéric Dardel, Isabelle Artaud, Thierry Meinnel. J Med Chem 2007
Adrien Boularot, Carmela Giglione, Sylvain Petit, Yann Duroc, Rodolphe Alves de Sousa, Valéry Larue, Thierry Cresteil, Frédéric Dardel, Isabelle Artaud, Thierry Meinnel. J Med Chem 2007
19
A peptide deformylase-ribosome complex reveals mechanism of nascent chain processing.
Rouven Bingel-Erlenmeyer, Rebecca Kohler, Günter Kramer, Arzu Sandikci, Snjezana Antolić, Timm Maier, Christiane Schaffitzel, Brigitte Wiedmann, Bernd Bukau, Nenad Ban. Nature 2008
Rouven Bingel-Erlenmeyer, Rebecca Kohler, Günter Kramer, Arzu Sandikci, Snjezana Antolić, Timm Maier, Christiane Schaffitzel, Brigitte Wiedmann, Bernd Bukau, Nenad Ban. Nature 2008
17
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.