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Times Cited: 635
Times Cited
Times Co-cited
Similarity
55
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
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Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.
Michelle Gray, Dyna I Shirasaki, Carlos Cepeda, Véronique M André, Brian Wilburn, Xiao-Hong Lu, Jifang Tao, Irene Yamazaki, Shi-Hua Li, Yi E Sun,[...]. J Neurosci 2008
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44
Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
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Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin.
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34
Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats.
Liliana B Menalled, Jessica D Sison, Ioannis Dragatsis, Scott Zeitlin, Marie-Françoise Chesselet. J Comp Neurol 2003
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Neurological abnormalities in a knock-in mouse model of Huntington's disease.
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28
Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.
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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
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Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice.
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19
Huntington's disease: from molecular pathogenesis to clinical treatment.
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Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
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Neuropathological classification of Huntington's disease.
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Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington's disease.
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Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice.
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Differential loss of striatal projection neurons in Huntington disease.
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Choosing an animal model for the study of Huntington's disease.
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Transgenic rat model of Huntington's disease.
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14
Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice.
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14
Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse.
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14
Molecular mechanisms and potential therapeutical targets in Huntington's disease.
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14
Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice.
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14
Network organization of the huntingtin proteomic interactome in mammalian brain.
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13
Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function.
L A Raymond, V M André, C Cepeda, C M Gladding, A J Milnerwood, M S Levine. Neuroscience 2011
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13
Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington disease.
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13
A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice.
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13
Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease.
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13
Impaired synaptic plasticity in mice carrying the Huntington's disease mutation.
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13
Huntington disease: natural history, biomarkers and prospects for therapeutics.
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13
Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue.
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The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease.
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13
Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of Huntington disease in the full-length BACHD and YAC128 mice.
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13
Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models.
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13
Normal huntingtin function: an alternative approach to Huntington's disease.
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12
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.
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12
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease.
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12
Longitudinal evaluation of the Hdh(CAG)150 knock-in murine model of Huntington's disease.
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12
Changes in cortical and striatal neurons predict behavioral and electrophysiological abnormalities in a transgenic murine model of Huntington's disease.
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12
Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease.
Carlos Cepeda, Raymond S Hurst, Christopher R Calvert, Elizabeth Hernández-Echeagaray, Oanh K Nguyen, Emily Jocoy, Lindsey J Christian, Marjorie A Ariano, Michael S Levine. J Neurosci 2003
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12
Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease.
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12
Regional and cellular gene expression changes in human Huntington's disease brain.
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12
Early development of aberrant synaptic plasticity in a mouse model of Huntington's disease.
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12
Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice.
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12
Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes.
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12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.