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Times Cited: 2859
Times Cited: 2859
Times Cited
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Similarity
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis.
P Puigserver, Z Wu, C W Park, R Graves, M Wright, B M Spiegelman. Cell 1998
P Puigserver, Z Wu, C W Park, R Graves, M Wright, B M Spiegelman. Cell 1998
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Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres.
Jiandie Lin, Hai Wu, Paul T Tarr, Chen-Yu Zhang, Zhidan Wu, Olivier Boss, Laura F Michael, Pere Puigserver, Eiji Isotani, Eric N Olson,[...]. Nature 2002
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AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha.
Sibylle Jäger, Christoph Handschin, Julie St-Pierre, Bruce M Spiegelman. Proc Natl Acad Sci U S A 2007
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Metabolic control through the PGC-1 family of transcription coactivators.
Jiandie Lin, Christoph Handschin, Bruce M Spiegelman. Cell Metab 2005
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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1.
Joseph T Rodgers, Carlos Lerin, Wilhelm Haas, Steven P Gygi, Bruce M Spiegelman, Pere Puigserver. Nature 2005
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Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators.
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Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis.
Pablo J Fernandez-Marcos, Johan Auwerx. Am J Clin Nutr 2011
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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.
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Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction.
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Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: a potential regulatory link between nuclear and mitochondrial gene expression in organelle biogenesis.
J V Virbasius, R C Scarpulla. Proc Natl Acad Sci U S A 1994
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PGC-1 coactivators: inducible regulators of energy metabolism in health and disease.
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Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway.
Takayuki Akimoto, Steven C Pohnert, Ping Li, Mei Zhang, Curtis Gumbs, Paul B Rosenberg, R Sanders Williams, Zhen Yan. J Biol Chem 2005
Takayuki Akimoto, Steven C Pohnert, Ping Li, Mei Zhang, Curtis Gumbs, Paul B Rosenberg, R Sanders Williams, Zhen Yan. J Biol Chem 2005
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Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator.
Pere Puigserver, Bruce M Spiegelman. Endocr Rev 2003
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The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes.
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Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis.
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Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network.
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The estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced mitochondrial biogenesis.
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Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha.
Zachary Gerhart-Hines, Joseph T Rodgers, Olivia Bare, Carles Lerin, Seung-Hee Kim, Raul Mostoslavsky, Frederick W Alt, Zhidan Wu, Pere Puigserver. EMBO J 2007
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Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.
K J Livak, T D Schmittgen. Methods 2001
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Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice.
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PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure.
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PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis.
Valerie S LeBleu, Joyce T O'Connell, Karina N Gonzalez Herrera, Harriet Wikman, Klaus Pantel, Marcia C Haigis, Fernanda Machado de Carvalho, Aline Damascena, Ludmilla Thome Domingos Chinen, Rafael M Rocha,[...]. Nat Cell Biol 2014
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Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1.
J C Yoon, P Puigserver, G Chen, J Donovan, Z Wu, J Rhee, G Adelmant, J Stafford, C R Kahn, D K Granner,[...]. Nature 2001
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Berberine activates thermogenesis in white and brown adipose tissue.
Zhiguo Zhang, Huizhi Zhang, Bo Li, Xiangjian Meng, Jiqiu Wang, Yifei Zhang, Shuangshuang Yao, Qinyun Ma, Lina Jin, Jian Yang,[...]. Nat Commun 2014
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Regulation of glucose transport by insulin: traffic control of GLUT4.
Dara Leto, Alan R Saltiel. Nat Rev Mol Cell Biol 2012
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Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals.
Christoph Handschin, Sherry Chin, Ping Li, Fenfen Liu, Eleftheria Maratos-Flier, Nathan K Lebrasseur, Zhen Yan, Bruce M Spiegelman. J Biol Chem 2007
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Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release.
Dmitry B Zorov, Magdalena Juhaszova, Steven J Sollott. Physiol Rev 2014
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AMPK: guardian of metabolism and mitochondrial homeostasis.
Sébastien Herzig, Reuben J Shaw. Nat Rev Mol Cell Biol 2018
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Muscle-specific expression of PPARgamma coactivator-1alpha improves exercise performance and increases peak oxygen uptake.
Jennifer A Calvo, Thomas G Daniels, Xiaomei Wang, Angelika Paul, Jiandie Lin, Bruce M Spiegelman, Susan C Stevenson, Shamina M Rangwala. J Appl Physiol (1985) 2008
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AMPK and PPARdelta agonists are exercise mimetics.
Vihang A Narkar, Michael Downes, Ruth T Yu, Emi Embler, Yong-Xu Wang, Ester Banayo, Maria M Mihaylova, Michael C Nelson, Yuhua Zou, Henry Juguilon,[...]. Cell 2008
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Power Grid Protection of the Muscle Mitochondrial Reticulum.
Brian Glancy, Lisa M Hartnell, Christian A Combs, Armel Femnou, Junhui Sun, Elizabeth Murphy, Sriram Subramaniam, Robert S Balaban. Cell Rep 2017
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Alterations of PPARalpha and its coactivator PGC-1 in cisplatin-induced acute renal failure.
Didier Portilla, Gonghe Dai, Timothy McClure, Linda Bates, Richard Kurten, Judit Megyesi, Peter Price, Shenyang Li. Kidney Int 2002
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Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress.
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Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes.
Kfir Sharabi, Hua Lin, Clint D J Tavares, John E Dominy, Joao Paulo Camporez, Rachel J Perry, Roger Schilling, Amy K Rines, Jaemin Lee, Marc Hickey,[...]. Cell 2017
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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.
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Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways.
Joseph T Rodgers, Carles Lerin, Zachary Gerhart-Hines, Pere Puigserver. FEBS Lett 2008
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Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1alpha.
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Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice.
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Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation.
Marc Uldry, Wenli Yang, Julie St-Pierre, Jiandie Lin, Patrick Seale, Bruce M Spiegelman. Cell Metab 2006
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Activation of PPARgamma coactivator-1 through transcription factor docking.
P Puigserver, G Adelmant, Z Wu, M Fan, J Xu, B O'Malley, B M Spiegelman. Science 1999
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Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human.
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NRF-1: a trans-activator of nuclear-encoded respiratory genes in animal cells.
M J Evans, R C Scarpulla. Genes Dev 1990
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Development of insulin resistance in mice lacking PGC-1α in adipose tissues.
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SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}.
Shino Nemoto, Maria M Fergusson, Toren Finkel. J Biol Chem 2005
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Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1.
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Transcriptional control of mitochondrial biogenesis: the central role of PGC-1alpha.
Renée Ventura-Clapier, Anne Garnier, Vladimir Veksler. Cardiovasc Res 2008
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Mitochondrial biogenesis in neurodegeneration.
P Andy Li, Xiaolin Hou, Shaocai Hao. J Neurosci Res 2017
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