A citation-based method for searching scientific literature


List of co-cited articles
1345 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Gli proteins in development and disease.
Chi-Chung Hui, Stephane Angers. Annu Rev Cell Dev Biol 2011
482
28

Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation.
Yong Pan, Chunyang Brian Bai, Alexandra L Joyner, Baolin Wang. Mol Cell Biol 2006
398
22

Patched1 regulates hedgehog signaling at the primary cilium.
Rajat Rohatgi, Ljiljana Milenkovic, Matthew P Scott. Science 2007
22

The mechanisms of Hedgehog signalling and its roles in development and disease.
James Briscoe, Pascal P Thérond. Nat Rev Mol Cell Biol 2013
21

Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3.
P Dai, H Akimaru, Y Tanaka, T Maekawa, M Nakafuku, S Ishii. J Biol Chem 1999
434
21


Vertebrate Smoothened functions at the primary cilium.
Kevin C Corbit, Pia Aanstad, Veena Singla, Andrew R Norman, Didier Y R Stainier, Jeremy F Reiter. Nature 2005
17

Hedgehog: functions and mechanisms.
Markku Varjosalo, Jussi Taipale. Genes Dev 2008
874
16

The primary cilium: a signalling centre during vertebrate development.
Sarah C Goetz, Kathryn V Anderson. Nat Rev Genet 2010
16

Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1.
P Kogerman, T Grimm, L Kogerman, D Krause, A B Undén, B Sandstedt, R Toftgård, P G Zaphiropoulos. Nat Cell Biol 1999
378
16

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists.
Matthias Lauth, Asa Bergström, Takashi Shimokawa, Rune Toftgård. Proc Natl Acad Sci U S A 2007
601
16

Mutations affecting segment number and polarity in Drosophila.
C Nüsslein-Volhard, E Wieschaus. Nature 1980
16

Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway.
C Brian Bai, Wojtek Auerbach, Joon S Lee, Daniel Stephen, Alexandra L Joyner. Development 2002
527
15

Activating Smoothened mutations in sporadic basal-cell carcinoma.
J Xie, M Murone, S M Luoh, A Ryan, Q Gu, C Zhang, J M Bonifas, C W Lam, M Hynes, A Goddard,[...]. Nature 1998
15

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins.
Eric W Humke, Karolin V Dorn, Ljiljana Milenkovic, Matthew P Scott, Rajat Rohatgi. Genes Dev 2010
328
14

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity.
Y Echelard, D J Epstein, B St-Jacques, L Shen, J Mohler, J A McMahon, A P McMahon. Cell 1993
13


Gli1 is a target of Sonic hedgehog that induces ventral neural tube development.
J Lee, K A Platt, P Censullo, A Ruiz i Altaba. Development 1997
485
13


Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function.
C Chiang, Y Litingtung, E Lee, K E Young, J L Corden, H Westphal, P A Beachy. Nature 1996
13

Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling.
Pawel Niewiadomski, Jennifer H Kong, Robert Ahrends, Yan Ma, Eric W Humke, Sohini Khan, Mary N Teruel, Bennett G Novitch, Rajat Rohatgi. Cell Rep 2014
155
13

Hedgehog signalling in the mouse requires intraflagellar transport proteins.
Danwei Huangfu, Aimin Liu, Andrew S Rakeman, Noel S Murcia, Lee Niswander, Kathryn V Anderson. Nature 2003
12

Hedgehog beyond medulloblastoma and basal cell carcinoma.
Stephan Teglund, Rune Toftgård. Biochim Biophys Acta 2010
342
12


Mutations in SUFU predispose to medulloblastoma.
Michael D Taylor, Ling Liu, Corey Raffel, Chi-chung Hui, Todd G Mainprize, Xiaoyun Zhang, Ron Agatep, Sharon Chiappa, Luzhang Gao, Anja Lowrance,[...]. Nat Genet 2002
575
12

Multisite protein kinase A and glycogen synthase kinase 3beta phosphorylation leads to Gli3 ubiquitination by SCFbetaTrCP.
Denis Tempé, Mariana Casas, Sonia Karaz, Marie-Françoise Blanchet-Tournier, Jean-Paul Concordet. Mol Cell Biol 2006
188
11

Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation.
H L Park, C Bai, K A Platt, M P Matise, A Beeghly, C C Hui, M Nakashima, A L Joyner. Development 2000
525
11

Human homolog of patched, a candidate gene for the basal cell nevus syndrome.
R L Johnson, A L Rothman, J Xie, L V Goodrich, J W Bare, J M Bonifas, A G Quinn, R M Myers, D R Cox, E H Epstein,[...]. Science 1996
11

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine.
J Taipale, J K Chen, M K Cooper, B Wang, R K Mann, L Milenkovic, M P Scott, P A Beachy. Nature 2000
11

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function.
Courtney J Haycraft, Boglarka Banizs, Yesim Aydin-Son, Qihong Zhang, Edward J Michaud, Bradley K Yoder. PLoS Genet 2005
677
11

The Hedgehog signal transduction network.
David J Robbins, Dennis Liang Fei, Natalia A Riobo. Sci Signal 2012
282
11

Gli1 can rescue the in vivo function of Gli2.
C B Bai, A L Joyner. Development 2001
223
10

Roles for Hedgehog signaling in adult organ homeostasis and repair.
Ralitsa Petrova, Alexandra L Joyner. Development 2014
239
10

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis.
Sarah P Thayer, Marina Pasca di Magliano, Patrick W Heiser, Corinne M Nielsen, Drucilla J Roberts, Gregory Y Lauwers, Yan Ping Qi, Stephan Gysin, Carlos Fernández-del Castillo, Vijay Yajnik,[...]. Nature 2003
10

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours.
David M Berman, Sunil S Karhadkar, Anirban Maitra, Rocio Montes De Oca, Meg R Gerstenblith, Kimberly Briggs, Antony R Parker, Yutaka Shimada, James R Eshleman, D Neil Watkins,[...]. Nature 2003
10

Cilia and Hedgehog responsiveness in the mouse.
Danwei Huangfu, Kathryn V Anderson. Proc Natl Acad Sci U S A 2005
615
10

The Gli code: an information nexus regulating cell fate, stemness and cancer.
Ariel Ruiz i Altaba, Christophe Mas, Barbara Stecca. Trends Cell Biol 2007
289
10


The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling.
Saikat Mukhopadhyay, Xiaohui Wen, Navneet Ratti, Alexander Loktev, Linda Rangell, Suzie J Scales, Peter K Jackson. Cell 2013
292
9

Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development.
R Mo, A M Freer, D L Zinyk, M A Crackower, J Michaud, H H Heng, K W Chik, X M Shi, L C Tsui, S H Cheng,[...]. Development 1997
480
9

Mechanisms and functions of Hedgehog signalling across the metazoa.
Philip W Ingham, Yoshiro Nakano, Claudia Seger. Nat Rev Genet 2011
410
9

Targeting the Hedgehog pathway in cancer.
Lee L Rubin, Frederic J de Sauvage. Nat Rev Drug Discov 2006
610
9


Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway.
Elspeth M Beauchamp, Lymor Ringer, Gülay Bulut, Kamal P Sajwan, Michael D Hall, Yi-Chien Lee, Daniel Peaceman, Metin Ozdemirli, Olga Rodriguez, Tobey J Macdonald,[...]. J Clin Invest 2011
253
9

Patched acts catalytically to suppress the activity of Smoothened.
J Taipale, M K Cooper, T Maiti, P A Beachy. Nature 2002
598
9

Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion.
Frédéric Varnat, Arnaud Duquet, Monica Malerba, Marie Zbinden, Christophe Mas, Pascal Gervaz, Ariel Ruiz i Altaba. EMBO Mol Med 2009
344
9

Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector.
Jynho Kim, John J Lee, James Kim, Dale Gardner, Philip A Beachy. Proc Natl Acad Sci U S A 2010
230
9

Essential role of stromally induced hedgehog signaling in B-cell malignancies.
Christine Dierks, Jovana Grbic, Katja Zirlik, Ronak Beigi, Nathan P Englund, Gui-Rong Guo, Hendrik Veelken, Monika Engelhardt, Roland Mertelsmann, Joseph F Kelleher,[...]. Nat Med 2007
257
9

A paracrine requirement for hedgehog signalling in cancer.
Robert L Yauch, Stephen E Gould, Suzie J Scales, Tracy Tang, Hua Tian, Christina P Ahn, Derek Marshall, Ling Fu, Thomas Januario, Dara Kallop,[...]. Nature 2008
761
9

Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.
Robert L Yauch, Gerrit J P Dijkgraaf, Bruno Alicke, Thomas Januario, Christina P Ahn, Thomas Holcomb, Kanan Pujara, Jeremy Stinson, Christopher A Callahan, Tracy Tang,[...]. Science 2009
649
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.