D W Cushman, M A Ondetti. Nat Med 1999
Times Cited: 130
Times Cited: 130
Times Cited
Times Co-cited
Similarity
Design of specific inhibitors of angiotensin-converting enzyme: new class of orally active antihypertensive agents.
M A Ondetti, B Rubin, D W Cushman. Science 1977
M A Ondetti, B Rubin, D W Cushman. Science 1977
16
Crystal structure of the human angiotensin-converting enzyme-lisinopril complex.
Ramanathan Natesh, Sylva L U Schwager, Edward D Sturrock, K Ravi Acharya. Nature 2003
Ramanathan Natesh, Sylva L U Schwager, Edward D Sturrock, K Ravi Acharya. Nature 2003
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Design of potent competitive inhibitors of angiotensin-converting enzyme. Carboxyalkanoyl and mercaptoalkanoyl amino acids.
D W Cushman, H S Cheung, E F Sabo, M A Ondetti. Biochemistry 1977
D W Cushman, H S Cheung, E F Sabo, M A Ondetti. Biochemistry 1977
14
Isolation of bradykinin-potentiating peptides from Bothrops jararaca venom.
S H Ferreira, D C Bartelt, L J Greene. Biochemistry 1970
S H Ferreira, D C Bartelt, L J Greene. Biochemistry 1970
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A BRADYKININ-POTENTIATING FACTOR (BPF) PRESENT IN THE VENOM OF BOTHROPS JARARCA.
S H FERREIRA. Br J Pharmacol Chemother 1965
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Angiotensin-converting enzyme inhibitors from the venom of Bothrops jararaca. Isolation, elucidation of structure, and synthesis.
M A Ondetti, N J Williams, E F Sabo, J Pluscec, E R Weaver, O Kocy. Biochemistry 1971
M A Ondetti, N J Williams, E F Sabo, J Pluscec, E R Weaver, O Kocy. Biochemistry 1971
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Venoms as a platform for human drugs: translating toxins into therapeutics.
Glenn F King. Expert Opin Biol Ther 2011
Glenn F King. Expert Opin Biol Ther 2011
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The Bradykinin-potentiating peptides from venom gland and brain of Bothrops jararaca contain highly site specific inhibitors of the somatic angiotensin-converting enzyme.
Mirian A F Hayashi, Antonio C M Camargo. Toxicon 2005
Mirian A F Hayashi, Antonio C M Camargo. Toxicon 2005
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Identification of five new bradykinin potentiating peptides (BPPs) from Bothrops jararaca crude venom by using electrospray ionization tandem mass spectrometry after a two-step liquid chromatography.
Danielle Ianzer, Katsuhiro Konno, Rafael Marques-Porto, Fernanda Calheta Vieira Portaro, Reto Stöcklin, Antônio Carlos Martins de Camargo, Daniel Carvalho Pimenta. Peptides 2004
Danielle Ianzer, Katsuhiro Konno, Rafael Marques-Porto, Fernanda Calheta Vieira Portaro, Reto Stöcklin, Antônio Carlos Martins de Camargo, Daniel Carvalho Pimenta. Peptides 2004
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Ziconotide: neuronal calcium channel blocker for treating severe chronic pain.
G P Miljanich. Curr Med Chem 2004
G P Miljanich. Curr Med Chem 2004
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Cloning and sequence analysis of a Bothrops jararaca cDNA encoding a precursor of seven bradykinin-potentiating peptides and a C-type natriuretic peptide.
N Murayama, M A Hayashi, H Ohi, L A Ferreira, V V Hermann, H Saito, Y Fujita, S Higuchi, B L Fernandes, T Yamane,[...]. Proc Natl Acad Sci U S A 1997
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Ace revisited: a new target for structure-based drug design.
K Ravi Acharya, Edward D Sturrock, James F Riordan, Mario R W Ehlers. Nat Rev Drug Discov 2003
K Ravi Acharya, Edward D Sturrock, James F Riordan, Mario R W Ehlers. Nat Rev Drug Discov 2003
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Structural details on the binding of antihypertensive drugs captopril and enalaprilat to human testicular angiotensin I-converting enzyme.
Ramanathan Natesh, Sylva L U Schwager, Hazel R Evans, Edward D Sturrock, K Ravi Acharya. Biochemistry 2004
Ramanathan Natesh, Sylva L U Schwager, Hazel R Evans, Edward D Sturrock, K Ravi Acharya. Biochemistry 2004
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The two homologous domains of human angiotensin I-converting enzyme interact differently with competitive inhibitors.
L Wei, E Clauser, F Alhenc-Gelas, P Corvol. J Biol Chem 1992
L Wei, E Clauser, F Alhenc-Gelas, P Corvol. J Biol Chem 1992
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The preparation and function of the hypertensin-converting enzyme.
L T SKEGGS, J R KAHN, N P SHUMWAY. J Exp Med 1956
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The C-type natriuretic peptide precursor of snake brain contains highly specific inhibitors of the angiotensin-converting enzyme.
Mirian A F Hayashi, Alessandra F Murbach, Danielle Ianzer, Fernanda C V Portaro, Benedito C Prezoto, Beatriz L Fernandes, Paulo F Silveira, Carlos A Silva, Raquel S Pires, Luiz R G Britto,[...]. J Neurochem 2003
Mirian A F Hayashi, Alessandra F Murbach, Danielle Ianzer, Fernanda C V Portaro, Benedito C Prezoto, Beatriz L Fernandes, Paulo F Silveira, Carlos A Silva, Raquel S Pires, Luiz R G Britto,[...]. J Neurochem 2003
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Contribution of kinins to the cardiovascular actions of angiotensin-converting enzyme inhibitors.
W Linz, G Wiemer, P Gohlke, T Unger, B A Schölkens. Pharmacol Rev 1995
W Linz, G Wiemer, P Gohlke, T Unger, B A Schölkens. Pharmacol Rev 1995
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Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides.
Geoffrey Masuyer, Sylva L U Schwager, Edward D Sturrock, R Elwyn Isaac, K Ravi Acharya. Sci Rep 2012
Geoffrey Masuyer, Sylva L U Schwager, Edward D Sturrock, R Elwyn Isaac, K Ravi Acharya. Sci Rep 2012
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Cloning and characterisation of natriuretic peptides from the venom glands of Australian elapids.
Liam St Pierre, Simone Flight, Paul P Masci, Kim J Hanchard, Richard J Lewis, Paul F Alewood, John de Jersey, Martin F Lavin. Biochimie 2006
Liam St Pierre, Simone Flight, Paul P Masci, Kim J Hanchard, Richard J Lewis, Paul F Alewood, John de Jersey, Martin F Lavin. Biochimie 2006
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Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning.
F Soubrier, F Alhenc-Gelas, C Hubert, J Allegrini, M John, G Tregear, P Corvol. Proc Natl Acad Sci U S A 1988
F Soubrier, F Alhenc-Gelas, C Hubert, J Allegrini, M John, G Tregear, P Corvol. Proc Natl Acad Sci U S A 1988
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Hypotensive peptides from milk proteins.
Richard J FitzGerald, Brian A Murray, Daniel J Walsh. J Nutr 2004
Richard J FitzGerald, Brian A Murray, Daniel J Walsh. J Nutr 2004
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History of the design of captopril and related inhibitors of angiotensin converting enzyme.
D W Cushman, M A Ondetti. Hypertension 1991
D W Cushman, M A Ondetti. Hypertension 1991
6
A new member of the natriuretic peptide family is present in the venom of the green mamba (Dendroaspis angusticeps).
H Schweitz, P Vigne, D Moinier, C Frelin, M Lazdunski. J Biol Chem 1992
H Schweitz, P Vigne, D Moinier, C Frelin, M Lazdunski. J Biol Chem 1992
6
Drug development from Australian elapid snake venoms and the Venomics pipeline of candidates for haemostasis: Textilinin-1 (Q8008), Haempatch™ (Q8009) and CoVase™ (V0801).
Stephen T H Earl, Paul P Masci, John de Jersey, Martin F Lavin, Janette Dixon. Toxicon 2012
Stephen T H Earl, Paul P Masci, John de Jersey, Martin F Lavin, Janette Dixon. Toxicon 2012
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Bradykinin-potentiating peptides: beyond captopril.
Antonio C M Camargo, Danielle Ianzer, Juliano R Guerreiro, Solange M T Serrano. Toxicon 2012
Antonio C M Camargo, Danielle Ianzer, Juliano R Guerreiro, Solange M T Serrano. Toxicon 2012
7
From snake venom toxins to therapeutics--cardiovascular examples.
Cho Yeow Koh, R Manjunatha Kini. Toxicon 2012
Cho Yeow Koh, R Manjunatha Kini. Toxicon 2012
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Novel natriuretic peptides from the venom of the inland taipan (Oxyuranus microlepidotus): isolation, chemical and biological characterisation.
Bryan G Fry, Janith C Wickramaratana, Scott Lemme, Anne Beuve, David Garbers, Wayne C Hodgson, Paul Alewood. Biochem Biophys Res Commun 2005
Bryan G Fry, Janith C Wickramaratana, Scott Lemme, Anne Beuve, David Garbers, Wayne C Hodgson, Paul Alewood. Biochem Biophys Res Commun 2005
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Differences in the properties and enzymatic specificities of the two active sites of angiotensin I-converting enzyme (kininase II). Studies with bradykinin and other natural peptides.
E Jaspard, L Wei, F Alhenc-Gelas. J Biol Chem 1993
E Jaspard, L Wei, F Alhenc-Gelas. J Biol Chem 1993
5
Selective inhibition of the C-domain of angiotensin I converting enzyme by bradykinin potentiating peptides.
Joël Cotton, Mirian A F Hayashi, Philippe Cuniasse, Gilles Vazeux, Danielle Ianzer, Antonio C M De Camargo, Vincent Dive. Biochemistry 2002
Joël Cotton, Mirian A F Hayashi, Philippe Cuniasse, Gilles Vazeux, Danielle Ianzer, Antonio C M De Camargo, Vincent Dive. Biochemistry 2002
8
Angiotensin-converting enzyme: zinc- and inhibitor-binding stoichiometries of the somatic and testis isozymes.
M R Ehlers, J F Riordan. Biochemistry 1991
M R Ehlers, J F Riordan. Biochemistry 1991
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Global burden of hypertension: analysis of worldwide data.
Patricia M Kearney, Megan Whelton, Kristi Reynolds, Paul Muntner, Paul K Whelton, Jiang He. Lancet 2005
Patricia M Kearney, Megan Whelton, Kristi Reynolds, Paul Muntner, Paul K Whelton, Jiang He. Lancet 2005
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Binding of the by-product analog benzylsuccinic acid by carboxypeptidase A.
L D Byers, R Wolfenden. Biochemistry 1973
L D Byers, R Wolfenden. Biochemistry 1973
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Calciseptine, a peptide isolated from black mamba venom, is a specific blocker of the L-type calcium channel.
J R de Weille, H Schweitz, P Maes, A Tartar, M Lazdunski. Proc Natl Acad Sci U S A 1991
J R de Weille, H Schweitz, P Maes, A Tartar, M Lazdunski. Proc Natl Acad Sci U S A 1991
5
Argininosuccinate synthetase is a functional target for a snake venom anti-hypertensive peptide: role in arginine and nitric oxide production.
Juliano R Guerreiro, Claudiana Lameu, Eduardo F Oliveira, Clécio F Klitzke, Robson L Melo, Edlaine Linares, Ohara Augusto, Jay W Fox, Ivo Lebrun, Solange M T Serrano,[...]. J Biol Chem 2009
Juliano R Guerreiro, Claudiana Lameu, Eduardo F Oliveira, Clécio F Klitzke, Robson L Melo, Edlaine Linares, Ohara Augusto, Jay W Fox, Ivo Lebrun, Solange M T Serrano,[...]. J Biol Chem 2009
10
Isolation: analysis and properties of three bradykinin-potentiating peptides (BPP-II, BPP-III, and BPP-V) from Bothrops neuwiedi venom.
L A Ferreira, A Galle, M Raida, M Schrader, I Lebrun, G Habermehl. J Protein Chem 1998
L A Ferreira, A Galle, M Raida, M Schrader, I Lebrun, G Habermehl. J Protein Chem 1998
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High-resolution crystal structures of Drosophila melanogaster angiotensin-converting enzyme in complex with novel inhibitors and antihypertensive drugs.
Mohd Akif, Dimitris Georgiadis, Aman Mahajan, Vincent Dive, Edward D Sturrock, R Elwyn Isaac, K Ravi Acharya. J Mol Biol 2010
Mohd Akif, Dimitris Georgiadis, Aman Mahajan, Vincent Dive, Edward D Sturrock, R Elwyn Isaac, K Ravi Acharya. J Mol Biol 2010
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The engineering of an orally active conotoxin for the treatment of neuropathic pain.
Richard J Clark, Jonas Jensen, Simon T Nevin, Brid P Callaghan, David J Adams, David J Craik. Angew Chem Int Ed Engl 2010
Richard J Clark, Jonas Jensen, Simon T Nevin, Brid P Callaghan, David J Adams, David J Craik. Angew Chem Int Ed Engl 2010
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UCSF Chimera--a visualization system for exploratory research and analysis.
Eric F Pettersen, Thomas D Goddard, Conrad C Huang, Gregory S Couch, Daniel M Greenblatt, Elaine C Meng, Thomas E Ferrin. J Comput Chem 2004
Eric F Pettersen, Thomas D Goddard, Conrad C Huang, Gregory S Couch, Daniel M Greenblatt, Elaine C Meng, Thomas E Ferrin. J Comput Chem 2004
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Proline rich-oligopeptides: diverse mechanisms for antihypertensive action.
Katia L P Morais, Danielle Ianzer, José Rodolfo R Miranda, Robson L Melo, Juliano R Guerreiro, Robson A S Santos, Henning Ulrich, Claudiana Lameu. Peptides 2013
Katia L P Morais, Danielle Ianzer, José Rodolfo R Miranda, Robson L Melo, Juliano R Guerreiro, Robson A S Santos, Henning Ulrich, Claudiana Lameu. Peptides 2013
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Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril.
I García-Sáez, P S Mercuri, C Papamicael, R Kahn, J M Frère, M Galleni, G M Rossolini, O Dideberg. J Mol Biol 2003
I García-Sáez, P S Mercuri, C Papamicael, R Kahn, J M Frère, M Galleni, G M Rossolini, O Dideberg. J Mol Biol 2003
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Metallo-beta-lactamases: novel weaponry for antibiotic resistance in bacteria.
Michael W Crowder, James Spencer, Alejandro J Vila. Acc Chem Res 2006
Michael W Crowder, James Spencer, Alejandro J Vila. Acc Chem Res 2006
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Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers.
Jürgen Brem, Sander S van Berkel, David Zollman, Sook Y Lee, Opher Gileadi, Peter J McHugh, Timothy R Walsh, Michael A McDonough, Christopher J Schofield. Antimicrob Agents Chemother 2015
Jürgen Brem, Sander S van Berkel, David Zollman, Sook Y Lee, Opher Gileadi, Peter J McHugh, Timothy R Walsh, Michael A McDonough, Christopher J Schofield. Antimicrob Agents Chemother 2015
5
Metallo-beta-lactamases (classification, activity, genetic organization, structure, zinc coordination) and their superfamily.
Carine Bebrone. Biochem Pharmacol 2007
Carine Bebrone. Biochem Pharmacol 2007
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New Delhi metallo-β-lactamase: structural insights into β-lactam recognition and inhibition.
Dustin T King, Liam J Worrall, Robert Gruninger, Natalie C J Strynadka. J Am Chem Soc 2012
Dustin T King, Liam J Worrall, Robert Gruninger, Natalie C J Strynadka. J Am Chem Soc 2012
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Coordination geometries of metal ions in d- or l-captopril-inhibited metallo-beta-lactamases.
Uwe Heinz, Rogert Bauer, Sandra Wommer, Wolfram Meyer-Klaucke, Cyril Papamichaels, John Bateson, Hans-Werner Adolph. J Biol Chem 2003
Uwe Heinz, Rogert Bauer, Sandra Wommer, Wolfram Meyer-Klaucke, Cyril Papamichaels, John Bateson, Hans-Werner Adolph. J Biol Chem 2003
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The development of Byetta (exenatide) from the venom of the Gila monster as an anti-diabetic agent.
Brian L Furman. Toxicon 2012
Brian L Furman. Toxicon 2012
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Venom peptides as therapeutics: advances, challenges and the future of venom-peptide discovery.
Samuel D Robinson, Eivind A B Undheim, Beatrix Ueberheide, Glenn F King. Expert Rev Proteomics 2017
Samuel D Robinson, Eivind A B Undheim, Beatrix Ueberheide, Glenn F King. Expert Rev Proteomics 2017
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5
Early evolution of the venom system in lizards and snakes.
Bryan G Fry, Nicolas Vidal, Janette A Norman, Freek J Vonk, Holger Scheib, S F Ryan Ramjan, Sanjaya Kuruppu, Kim Fung, S Blair Hedges, Michael K Richardson,[...]. Nature 2006
Bryan G Fry, Nicolas Vidal, Janette A Norman, Freek J Vonk, Holger Scheib, S F Ryan Ramjan, Sanjaya Kuruppu, Kim Fung, S Blair Hedges, Michael K Richardson,[...]. Nature 2006
4
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.