A citation-based method for searching scientific literature

W C Hahn, S A Stewart, M W Brooks, S G York, E Eaton, A Kurachi, R L Beijersbergen, J H Knoll, M Meyerson, R A Weinberg. Nat Med 1999
Times Cited: 843







List of co-cited articles
985 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
36

A survey of telomerase activity in human cancer.
J W Shay, S Bacchetti. Eur J Cancer 1997
23

Extension of life-span by introduction of telomerase into normal human cells.
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
22

Telomeres shorten during ageing of human fibroblasts.
C B Harley, A B Futcher, C W Greider. Nature 1990
18



The RNA component of human telomerase.
J Feng, W D Funk, S S Wang, S L Weinrich, A A Avilion, C P Chiu, R R Adams, E Chang, R C Allsopp, J Yu. Science 1995
14

Highly recurrent TERT promoter mutations in human melanoma.
Franklin W Huang, Eran Hodis, Mary Jue Xu, Gregory V Kryukov, Lynda Chin, Levi A Garraway. Science 2013
14

TERT promoter mutations in familial and sporadic melanoma.
Susanne Horn, Adina Figl, P Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki,[...]. Science 2013
14

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
12

Telomere shortening and apoptosis in telomerase-inhibited human tumor cells.
X Zhang, V Mar, W Zhou, L Harrington, M O Robinson. Genes Dev 1999
561
12

Telomerase catalytic subunit homologs from fission yeast and human.
T M Nakamura, G B Morin, K B Chapman, S L Weinrich, W H Andrews, J Lingner, C B Harley, T R Cech. Science 1997
12

A DNA damage checkpoint response in telomere-initiated senescence.
Fabrizio d'Adda di Fagagna, Philip M Reaper, Lorena Clay-Farrace, Heike Fiegler, Philippa Carr, Thomas Von Zglinicki, Gabriele Saretzki, Nigel P Carter, Stephen P Jackson. Nature 2003
12

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death.
B Herbert, A E Pitts, S I Baker, S E Hamilton, W E Wright, J W Shay, D R Corey. Proc Natl Acad Sci U S A 1999
450
11

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
Patrick J Killela, Zachary J Reitman, Yuchen Jiao, Chetan Bettegowda, Nishant Agrawal, Luis A Diaz, Allan H Friedman, Henry Friedman, Gary L Gallia, Beppino C Giovanella,[...]. Proc Natl Acad Sci U S A 2013
829
11

Frequency of TERT promoter mutations in human cancers.
João Vinagre, Ana Almeida, Helena Pópulo, Rui Batista, Joana Lyra, Vasco Pinto, Ricardo Coelho, Ricardo Celestino, Hugo Prazeres, Luis Lima,[...]. Nat Commun 2013
496
10

Telomeres and telomerase in cancer.
Steven E Artandi, Ronald A DePinho. Carcinogenesis 2010
486
10

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization.
M Meyerson, C M Counter, E N Eaton, L W Ellisen, P Steiner, S D Caddle, L Ziaugra, R L Beijersbergen, M J Davidoff, Q Liu,[...]. Cell 1997
10

Cancer. TERT promoter mutations and telomerase reactivation in urothelial cancer.
Sumit Borah, Linghe Xi, Arthur J Zaug, Natasha M Powell, Garrett M Dancik, Scott B Cohen, James C Costello, Dan Theodorescu, Thomas R Cech. Science 2015
186
10

A highly selective telomerase inhibitor limiting human cancer cell proliferation.
K Damm, U Hemmann, P Garin-Chesa, N Hauel, I Kauffmann, H Priepke, C Niestroj, C Daiber, B Enenkel, B Guilliard,[...]. EMBO J 2001
305
10



Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies.
Mohammad A Jafri, Shakeel A Ansari, Mohammed H Alqahtani, Jerry W Shay. Genome Med 2016
202
10

Inhibition of human telomerase by a G-quadruplex-interactive compound.
D Sun, B Thompson, B E Cathers, M Salazar, S M Kerwin, J O Trent, T C Jenkins, S Neidle, L H Hurley. J Med Chem 1997
564
9

Mammalian telomeres end in a large duplex loop.
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
9


Alternative lengthening of telomeres: models, mechanisms and implications.
Anthony J Cesare, Roger R Reddel. Nat Rev Genet 2010
541
9

Telomerase directly regulates NF-κB-dependent transcription.
Arkasubhra Ghosh, Gaye Saginc, Shi Chi Leow, Ekta Khattar, Eun Myong Shin, Ting Dong Yan, Marc Wong, Zhizhuo Zhang, Guoliang Li, Wing-Kin Sung,[...]. Nat Cell Biol 2012
203
9

Telomerase activity in human germline and embryonic tissues and cells.
W E Wright, M A Piatyszek, W E Rainey, W Byrd, J W Shay. Dev Genet 1996
942
9

Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.
Agnel Sfeir, Settapong T Kosiyatrakul, Dirk Hockemeyer, Sheila L MacRae, Jan Karlseder, Carl L Schildkraut, Titia de Lange. Cell 2009
627
8

TRF2 protects human telomeres from end-to-end fusions.
B van Steensel, A Smogorzewska, T de Lange. Cell 1998
8

Telomerase and cancer therapeutics.
Calvin B Harley. Nat Rev Cancer 2008
461
8

Telomerase modulates Wnt signalling by association with target gene chromatin.
Jae-Il Park, Andrew S Venteicher, Ji Yeon Hong, Jinkuk Choi, Sohee Jun, Marina Shkreli, Woody Chang, Zhaojing Meng, Peggie Cheung, Hong Ji,[...]. Nature 2009
423
8

Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer.
Robert J A Bell, H Tomas Rube, Alex Kreig, Andrew Mancini, Shaun D Fouse, Raman P Nagarajan, Serah Choi, Chibo Hong, Daniel He, Melike Pekmezci,[...]. Science 2015
283
8

DNA damage foci at dysfunctional telomeres.
Hiroyuki Takai, Agata Smogorzewska, Titia de Lange. Curr Biol 2003
953
8

How shelterin protects mammalian telomeres.
Wilhelm Palm, Titia de Lange. Annu Rev Genet 2008
8


Telomerase maintains telomere structure in normal human cells.
Kenkichi Masutomi, Evan Y Yu, Shilagardy Khurts, Ittai Ben-Porath, Jennifer L Currier, Geoffrey B Metz, Mary W Brooks, Shuichi Kaneko, Seishi Murakami, James A DeCaprio,[...]. Cell 2003
573
8

Telomerase: central regulator of all of the hallmarks of cancer.
Kee Chung Low, Vinay Tergaonkar. Trends Biochem Sci 2013
152
8

Mechanism of human telomerase inhibition by BIBR1532, a synthetic, non-nucleosidic drug candidate.
Emanuelle Pascolo, Christian Wenz, Joachim Lingner, Norbert Hauel, Henning Priepke, Iris Kauffmann, Pilar Garin-Chesa, Wolfgang J Rettig, Klaus Damm, Andreas Schnapp. J Biol Chem 2002
185
8

Novel anticancer therapeutics targeting telomerase.
Maria Ruden, Neelu Puri. Cancer Treat Rev 2013
187
8

The structure and function of telomerase reverse transcriptase.
Chantal Autexier, Neal F Lue. Annu Rev Biochem 2006
319
7

Detection of telomerase activity in high concentration of cell lysates using primer-modified gold nanoparticles.
Yi Xiao, Karen Y Dane, Takanori Uzawa, Andrew Csordas, Jiangrong Qian, H Tom Soh, Patrick S Daugherty, Eric T Lagally, Alan J Heeger, Kevin W Plaxco. J Am Chem Soc 2010
73
9



Telomerase therapeutics for cancer: challenges and new directions.
Jerry W Shay, Woodring E Wright. Nat Rev Drug Discov 2006
297
7


Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice.
S E Artandi, S Chang, S L Lee, S Alson, G J Gottlieb, L Chin, R A DePinho. Nature 2000
828
7

Cancer-associated TERT promoter mutations abrogate telomerase silencing.
Kunitoshi Chiba, Joshua Z Johnson, Jacob M Vogan, Tina Wagner, John M Boyle, Dirk Hockemeyer. Elife 2015
136
7

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.
C M Counter, A A Avilion, C E LeFeuvre, N G Stewart, C W Greider, C B Harley, S Bacchetti. EMBO J 1992
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.