A citation-based method for searching scientific literature

D D Schoepp, D E Jane, J A Monn. Neuropharmacology 1999
Times Cited: 878







List of co-cited articles
1115 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Metabotropic glutamate receptors: physiology, pharmacology, and disease.
Colleen M Niswender, P Jeffrey Conn. Annu Rev Pharmacol Toxicol 2010
36

Pharmacology and functions of metabotropic glutamate receptors.
P J Conn, J P Pin. Annu Rev Pharmacol Toxicol 1997
28

Metabotropic glutamate receptors: from the workbench to the bedside.
F Nicoletti, J Bockaert, G L Collingridge, P J Conn, F Ferraguti, D D Schoepp, J T Wroblewski, J P Pin. Neuropharmacology 2011
417
17

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial.
Sandeep T Patil, Lu Zhang, Ferenc Martenyi, Stephen L Lowe, Kimberley A Jackson, Boris V Andreev, Alla S Avedisova, Leonid M Bardenstein, Issak Y Gurovich, Margarita A Morozova,[...]. Nat Med 2007
787
17


Structures of the extracellular regions of the group II/III metabotropic glutamate receptors.
Takanori Muto, Daisuke Tsuchiya, Kosuke Morikawa, Hisato Jingami. Proc Natl Acad Sci U S A 2007
266
13

Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor.
N Kunishima, Y Shimada, Y Tsuji, T Sato, M Yamamoto, T Kumasaka, S Nakanishi, H Jingami, K Morikawa. Nature 2000
936
13

The glutamate homeostasis hypothesis of addiction.
Peter W Kalivas. Nat Rev Neurosci 2009
834
13

A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo.
Kayo Mitsukawa, Rina Yamamoto, Silvio Ofner, Joachim Nozulak, Oliver Pescott, Snezana Lukic, Natacha Stoehr, Cedric Mombereau, Rainer Kuhn, Kevin H McAllister,[...]. Proc Natl Acad Sci U S A 2005
196
12

Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain.
Andrew S Doré, Krzysztof Okrasa, Jayesh C Patel, Maria Serrano-Vega, Kirstie Bennett, Robert M Cooke, James C Errey, Ali Jazayeri, Samir Khan, Ben Tehan,[...]. Nature 2014
290
12


Identification of a serotonin/glutamate receptor complex implicated in psychosis.
Javier González-Maeso, Rosalind L Ang, Tony Yuen, Pokman Chan, Noelia V Weisstaub, Juan F López-Giménez, Mingming Zhou, Yuuya Okawa, Luis F Callado, Graeme Milligan,[...]. Nature 2008
563
12

Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS.
Shen Yin, Meredith J Noetzel, Kari A Johnson, Rocio Zamorano, Nidhi Jalan-Sakrikar, Karen J Gregory, P Jeffrey Conn, Colleen M Niswender. J Neurosci 2014
82
14

Targeting metabotropic glutamate receptors for novel treatments of schizophrenia.
James Maksymetz, Sean P Moran, P Jeffrey Conn. Mol Brain 2017
69
17

Metabotropic glutamate receptors as novel targets for anxiety and stress disorders.
Chad J Swanson, Mark Bures, Michael P Johnson, Anni-Maija Linden, James A Monn, Darryle D Schoepp. Nat Rev Drug Discov 2005
464
11

Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator.
Huixian Wu, Chong Wang, Karen J Gregory, Gye Won Han, Hyekyung P Cho, Yan Xia, Colleen M Niswender, Vsevolod Katritch, Jens Meiler, Vadim Cherezov,[...]. Science 2014
363
11

Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus.
R Shigemoto, A Kinoshita, E Wada, S Nomura, H Ohishi, M Takada, P J Flor, A Neki, T Abe, S Nakanishi,[...]. J Neurosci 1997
848
11

2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist.
F Gasparini, K Lingenhöhl, N Stoehr, P J Flor, M Heinrich, I Vranesic, M Biollaz, H Allgeier, R Heckendorn, S Urwyler,[...]. Neuropharmacology 1999
646
10


Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia.
P Jeffrey Conn, Craig W Lindsley, Carrie K Jones. Trends Pharmacol Sci 2009
267
10



Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.
Daisuke Tsuchiya, Naoki Kunishima, Narutoshi Kamiya, Hisato Jingami, Kosuke Morikawa. Proc Natl Acad Sci U S A 2002
280
9

Pharmacological and pharmacokinetic properties of a structurally novel, potent, and selective metabotropic glutamate 2/3 receptor agonist: in vitro characterization of agonist (-)-(1R,4S,5S,6S)-4-amino-2-sulfonylbicyclo[3.1.0]-hexane-4,6-dicarboxylic acid (LY404039).
Linda M Rorick-Kehn, Bryan G Johnson, Jennifer L Burkey, Rebecca A Wright, David O Calligaro, Gerard J Marek, Eric S Nisenbaum, John T Catlow, Ann E Kingston, Deborah D Giera,[...]. J Pharmacol Exp Ther 2007
80
11


The metabotropic glutamate receptor 7 allosteric modulator AMN082: a monoaminergic agent in disguise?
Stacey J Sukoff Rizzo, Sarah K Leonard, Adam Gilbert, Paul Dollings, Deborah L Smith, Mei-Yi Zhang, Li Di, Brian J Platt, Sarah Neal, Jason M Dwyer,[...]. J Pharmacol Exp Ther 2011
82
10

Biased mGlu5-Positive Allosteric Modulators Provide In Vivo Efficacy without Potentiating mGlu5 Modulation of NMDAR Currents.
Jerri M Rook, Zixiu Xiang, Xiaohui Lv, Ayan Ghoshal, Jonathan W Dickerson, Thomas M Bridges, Kari A Johnson, Daniel J Foster, Karen J Gregory, Paige N Vinson,[...]. Neuron 2015
84
10



In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists.
Gentaroh Suzuki, Naohiro Tsukamoto, Hiroshi Fushiki, Aki Kawagishi, Masayuki Nakamura, Hideki Kurihara, Morihiro Mitsuya, Mitsuru Ohkubo, Hisashi Ohta. J Pharmacol Exp Ther 2007
104
8



Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders.
P Jeffrey Conn, Arthur Christopoulos, Craig W Lindsley. Nat Rev Drug Discov 2009
771
8

A multicenter, inpatient, phase 2, double-blind, placebo-controlled dose-ranging study of LY2140023 monohydrate in patients with DSM-IV schizophrenia.
Bruce J Kinon, Lu Zhang, Brian A Millen, Olawale O Osuntokun, Judy E Williams, Sara Kollack-Walker, Kimberley Jackson, Ludmila Kryzhanovskaya, Natalia Jarkova. J Clin Psychopharmacol 2011
176
8

Characterization of the novel positive allosteric modulator of the metabotropic glutamate receptor 4 ADX88178 in rodent models of neuropsychiatric disorders.
Mikhail Kalinichev, Emmanuel Le Poul, Christelle Boléa, Françoise Girard, Brice Campo, Massimiliano Fonsi, Isabelle Royer-Urios, Susan E Browne, Jason M Uslaner, Matthew J Davis,[...]. J Pharmacol Exp Ther 2014
48
16


Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders.
P Jeffrey Conn, Craig W Lindsley, Jens Meiler, Colleen M Niswender. Nat Rev Drug Discov 2014
180
8

Metabotropic glutamate receptor 5 is a disulfide-linked dimer.
C Romano, W L Yang, K L O'Malley. J Biol Chem 1996
416
8


ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization.
Mikhail Kalinichev, Mélanie Rouillier, Francoise Girard, Isabelle Royer-Urios, Bruno Bournique, Terry Finn, Delphine Charvin, Brice Campo, Emmanuel Le Poul, Vincent Mutel,[...]. J Pharmacol Exp Ther 2013
66
12

Blocking metabotropic glutamate receptor subtype 7 (mGlu7) via the Venus flytrap domain (VFTD) inhibits amygdala plasticity, stress, and anxiety-related behavior.
Christine E Gee, Daniel Peterlik, Christoph Neuhäuser, Rochdi Bouhelal, Klemens Kaupmann, Grit Laue, Nicole Uschold-Schmidt, Dominik Feuerbach, Kaspar Zimmermann, Silvio Ofner,[...]. J Biol Chem 2014
48
16

A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors.
Etienne Doumazane, Pauline Scholler, Jurriaan M Zwier, Eric Trinquet, Philippe Rondard, Jean-Philippe Pin. FASEB J 2011
199
8

Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinction.
Adam G Walker, Cody J Wenthur, Zixiu Xiang, Jerri M Rook, Kyle A Emmitte, Colleen M Niswender, Craig W Lindsley, P Jeffrey Conn. Proc Natl Acad Sci U S A 2015
65
12

Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity.
Richard H P Porter, Georg Jaeschke, Will Spooren, Theresa M Ballard, Bernd Büttelmann, Sabine Kolczewski, Jens-Uwe Peters, Eric Prinssen, Jürgen Wichmann, Eric Vieira,[...]. J Pharmacol Exp Ther 2005
231
7

LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors.
A E Kingston, P L Ornstein, R A Wright, B G Johnson, N G Mayne, J P Burnett, R Belagaje, S Wu, D D Schoepp. Neuropharmacology 1998
311
7



Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity.
Alice L Rodriguez, Mark D Grier, Carrie K Jones, Elizabeth J Herman, Alexander S Kane, Randy L Smith, Richard Williams, Ya Zhou, Joy E Marlo, Emily L Days,[...]. Mol Pharmacol 2010
145
7


Opposing efficacy of group III mGlu receptor activators, LSP1-2111 and AMN082, in animal models of positive symptoms of schizophrenia.
Joanna M Wierońska, Katarzyna Stachowicz, Francine Acher, Tomasz Lech, Andrzej Pilc. Psychopharmacology (Berl) 2012
53
13


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.