A citation-based method for searching scientific literature

Y Chai, S L Koppenhafer, N M Bonini, H L Paulson. J Neurosci 1999
Times Cited: 320







List of co-cited articles
1879 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.
J M Warrick, H Y Chan, G L Gray-Board, Y Chai, H L Paulson, N M Bonini. Nat Genet 1999
639
41

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.
C J Cummings, M A Mancini, B Antalffy, D B DeFranco, H T Orr, H Y Zoghbi. Nat Genet 1998
675
29

Heat shock transcription factor 1-activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones.
Nobuhiro Fujikake, Yoshitaka Nagai, H Akiko Popiel, Yuma Okamoto, Masamitsu Yamaguchi, Tatsushi Toda. J Biol Chem 2008
156
28


Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice.
C J Cummings, Y Sun, P Opal, B Antalffy, R Mestril, H T Orr, W H Dillmann, H Y Zoghbi. Hum Mol Genet 2001
363
25

CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1.
Y Kawaguchi, T Okamoto, M Taniwaki, M Aizawa, M Inoue, S Katayama, H Kawakami, S Nakamura, M Nishimura, I Akiguchi. Nat Genet 1994
23

Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.
H L Paulson, M K Perez, Y Trottier, J Q Trojanowski, S H Subramony, S S Das, P Vig, J L Mandel, K H Fischbeck, R N Pittman. Neuron 1997
658
22

Modulation of neurodegeneration by molecular chaperones.
Paul J Muchowski, Jennifer L Wacker. Nat Rev Neurosci 2005
715
21

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils.
P J Muchowski, G Schaffar, A Sittler, E E Wanker, M K Hayer-Hartl, F U Hartl. Proc Natl Acad Sci U S A 2000
472
21

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
20

Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila.
J M Warrick, H L Paulson, G L Gray-Board, Q T Bui, K H Fischbeck, R N Pittman, N M Bonini. Cell 1998
471
19

Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach.
David G Hay, Kirupa Sathasivam, Sönke Tobaben, Bernd Stahl, Michael Marber, Ruben Mestril, Amarbirpal Mahal, Donna L Smith, Ben Woodman, Gillian P Bates. Hum Mol Genet 2004
239
19

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease.
Pavan K Auluck, H Y Edwin Chan, John Q Trojanowski, Virginia M Y Lee, Nancy M Bonini. Science 2002
902
19

A DNAJB chaperone subfamily with HDAC-dependent activities suppresses toxic protein aggregation.
Jurre Hageman, Maria A Rujano, Maria A W H van Waarde, Vaishali Kakkar, Ron P Dirks, Natalia Govorukhina, Henderika M J Oosterveld-Hut, Nicolette H Lubsen, Harm H Kampinga. Mol Cell 2010
189
19

17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration.
Masahiro Waza, Hiroaki Adachi, Masahisa Katsuno, Makoto Minamiyama, Chen Sang, Fumiaki Tanaka, Akira Inukai, Manabu Doyu, Gen Sobue. Nat Med 2005
289
19

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
18

Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes.
Nihar Ranjan Jana, Priyanka Dikshit, Anand Goswami, Svetlana Kotliarova, Shigeo Murata, Keiji Tanaka, Nobuyuki Nukina. J Biol Chem 2005
232
18

Trinucleotide repeat disorders.
Harry T Orr, Huda Y Zoghbi. Annu Rev Neurosci 2007
966
17


Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease.
Masahisa Katsuno, Chen Sang, Hiroaki Adachi, Makoto Minamiyama, Masahiro Waza, Fumiaki Tanaka, Manabu Doyu, Gen Sobue. Proc Natl Acad Sci U S A 2005
183
17

Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease.
A Sittler, R Lurz, G Lueder, J Priller, H Lehrach, M K Hayer-Hartl, F U Hartl, E E Wanker. Hum Mol Genet 2001
328
17


Adapting proteostasis for disease intervention.
William E Balch, Richard I Morimoto, Andrew Dillin, Jeffery W Kelly. Science 2008
16

Protein misfolding, functional amyloid, and human disease.
Fabrizio Chiti, Christopher M Dobson. Annu Rev Biochem 2006
15

Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone.
D L Stenoien, C J Cummings, H P Adams, M G Mancini, K Patel, G N DeMartino, M Marcelli, N L Weigel, M A Mancini. Hum Mol Genet 1999
369
15


Glutamine repeats and neurodegeneration.
H Y Zoghbi, H T Orr. Annu Rev Neurosci 2000
957
15



Genetic suppression of polyglutamine toxicity in Drosophila.
P Kazemi-Esfarjani, S Benzer. Science 2000
422
15

Progressive disruption of cellular protein folding in models of polyglutamine diseases.
Tali Gidalevitz, Anat Ben-Zvi, Kim H Ho, Heather R Brignull, Richard I Morimoto. Science 2006
454
15

Axonal inclusions in spinocerebellar ataxia type 3.
Kay Seidel, Wilfred F A den Dunnen, Christian Schultz, Henry Paulson, Stefanie Frank, Rob A de Vos, Ewout R Brunt, Thomas Deller, Harm H Kampinga, Udo Rüb. Acta Neuropathol 2010
66
22

The HSP70 chaperone machinery: J proteins as drivers of functional specificity.
Harm H Kampinga, Elizabeth A Craig. Nat Rev Mol Cell Biol 2010
932
15

A toxic monomeric conformer of the polyglutamine protein.
Yoshitaka Nagai, Takashi Inui, H Akiko Popiel, Nobuhiro Fujikake, Kazuhiro Hasegawa, Yoshihiro Urade, Yuji Goto, Hironobu Naiki, Tatsushi Toda. Nat Struct Mol Biol 2007
232
14


Ataxin-3 suppresses polyglutamine neurodegeneration in Drosophila by a ubiquitin-associated mechanism.
John M Warrick, Lance M Morabito, Julide Bilen, Beth Gordesky-Gold, Lynn Z Faust, Henry L Paulson, Nancy M Bonini. Mol Cell 2005
197
14

Protein aggregation and neurodegenerative disease.
Christopher A Ross, Michelle A Poirier. Nat Med 2004
14

Ataxin-3 binds VCP/p97 and regulates retrotranslocation of ERAD substrates.
Xiaoyan Zhong, Randall N Pittman. Hum Mol Genet 2006
151
14

Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence.
Ulrike Bichelmeier, Thorsten Schmidt, Jeannette Hübener, Jana Boy, Lukas Rüttiger, Karina Häbig, Sven Poths, Michael Bonin, Marlies Knipper, Werner J Schmidt,[...]. J Neurosci 2007
132
14

Cellular toxicity of polyglutamine expansion proteins: mechanism of transcription factor deactivation.
Gregor Schaffar, Peter Breuer, Raina Boteva, Christian Behrends, Nikolay Tzvetkov, Nadine Strippel, Hideki Sakahira, Katja Siegers, Manajit Hayer-Hartl, F Ulrich Hartl. Mol Cell 2004
313
13

Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice.
Dairin Kieran, Bernadett Kalmar, James R T Dick, Joanna Riddoch-Contreras, Geoffrey Burnstock, Linda Greensmith. Nat Med 2004
364
13

Protein surveillance machinery in brains with spinocerebellar ataxia type 3: redistribution and differential recruitment of 26S proteasome subunits and chaperones to neuronal intranuclear inclusions.
Thorsten Schmidt, Katrin S Lindenberg, Antje Krebs, Ludger Schöls, Franco Laccone, Jochen Herms, Martin Rechsteiner, Olaf Riess, G Bernhard Landwehrmeyer. Ann Neurol 2002
104
13

A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration.
Daniel Goti, Scott M Katzen, Jesse Mez, Noam Kurtis, Jennifer Kiluk, Lea Ben-Haïem, Nancy A Jenkins, Neal G Copeland, Akira Kakizuka, Alan H Sharp,[...]. J Neurosci 2004
141
13


Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3.
Annette Haacke, Sarah A Broadley, Raina Boteva, Nikolay Tzvetkov, F Ulrich Hartl, Peter Breuer. Hum Mol Genet 2006
93
13

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract.
C L Wellington, L M Ellerby, A S Hackam, R L Margolis, M A Trifiro, R Singaraja, K McCutcheon, G S Salvesen, S S Propp, M Bromm,[...]. J Biol Chem 1998
422
13

Hsp70 Reduces alpha-Synuclein Aggregation and Toxicity.
Jochen Klucken, Youngah Shin, Eliezer Masliah, Bradley T Hyman, Pamela J McLean. J Biol Chem 2004
364
12

Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation.
M K Perez, H L Paulson, S J Pendse, S J Saionz, N M Bonini, R N Pittman. J Cell Biol 1998
256
12


Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin.
Andreas Wyttenbach, Olivier Sauvageot, Jenny Carmichael, Chantal Diaz-Latoud, Andre-Patrik Arrigo, David C Rubinsztein. Hum Mol Genet 2002
363
12


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.