A citation-based method for searching scientific literature

P Bouillet, D Metcalf, D C Huang, D M Tarlinton, T W Kay, F Köntgen, J M Adams, A Strasser. Science 1999
Times Cited: 1214







List of co-cited articles
931 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy.
Peter E Czabotar, Guillaume Lessene, Andreas Strasser, Jerry M Adams. Nat Rev Mol Cell Biol 2014
22

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa.
Andreas Villunger, Ewa M Michalak, Leigh Coultas, Franziska Müllauer, Gunther Böck, Michael J Ausserlechner, Jerry M Adams, Andreas Strasser. Science 2003
22

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.
T Lindsten, A J Ross, A King, W X Zong, J C Rathmell, H A Shiels, E Ulrich, K G Waymire, P Mahar, K Frauwirth,[...]. Mol Cell 2000
16

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes.
Philippe Bouillet, Jared F Purton, Dale I Godfrey, Li-Chen Zhang, Leigh Coultas, Hamsa Puthalakath, Marc Pellegrini, Suzanne Cory, Jerry M Adams, Andreas Strasser. Nature 2002
612
16

Bim: a novel member of the Bcl-2 family that promotes apoptosis.
L O'Connor, A Strasser, L A O'Reilly, G Hausmann, J M Adams, S Cory, D C Huang. EMBO J 1998
903
13

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets.
Andrew J Souers, Joel D Leverson, Erwin R Boghaert, Scott L Ackler, Nathaniel D Catron, Jun Chen, Brian D Dayton, Hong Ding, Sari H Enschede, Wayne J Fairbrother,[...]. Nat Med 2013
13

Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells.
Anselm Enders, Philippe Bouillet, Hamsa Puthalakath, Yuekang Xu, David M Tarlinton, Andreas Strasser. J Exp Med 2003
232
13

The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models.
András Kotschy, Zoltán Szlavik, James Murray, James Davidson, Ana Leticia Maragno, Gaëtane Le Toumelin-Braizat, Maïa Chanrion, Gemma L Kelly, Jia-Nan Gong, Donia M Moujalled,[...]. Nature 2016
583
12

Bim is a suppressor of Myc-induced mouse B cell leukemia.
Alexander Egle, Alan W Harris, Philippe Bouillet, Suzanne Cory. Proc Natl Acad Sci U S A 2004
394
11

Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia.
Andrew W Roberts, Matthew S Davids, John M Pagel, Brad S Kahl, Soham D Puvvada, John F Gerecitano, Thomas J Kipps, Mary Ann Anderson, Jennifer R Brown, Lori Gressick,[...]. N Engl J Med 2016
11


Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function.
Lin Chen, Simon N Willis, Andrew Wei, Brian J Smith, Jamie I Fletcher, Mark G Hinds, Peter M Colman, Catherine L Day, Jerry M Adams, David C S Huang. Mol Cell 2005
11


Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease.
A Strasser, S Whittingham, D L Vaux, M L Bath, J M Adams, S Cory, A W Harris. Proc Natl Acad Sci U S A 1991
781
10

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice.
N Motoyama, F Wang, K A Roth, H Sawa, K Nakayama, K Nakayama, I Negishi, S Senju, Q Zhang, S Fujii. Science 1995
982
10

XIAP discriminates between type I and type II FAS-induced apoptosis.
Philipp J Jost, Stephanie Grabow, Daniel Gray, Mark D McKenzie, Ueli Nachbur, David C S Huang, Philippe Bouillet, Helen E Thomas, Christoph Borner, John Silke,[...]. Nature 2009
300
9

ER stress triggers apoptosis by activating BH3-only protein Bim.
Hamsa Puthalakath, Lorraine A O'Reilly, Priscilla Gunn, Lily Lee, Priscilla N Kelly, Nicholas D Huntington, Peter D Hughes, Ewa M Michalak, Jennifer McKimm-Breschkin, Noburo Motoyama,[...]. Cell 2007
9



Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis.
Peter E Czabotar, Dana Westphal, Grant Dewson, Stephen Ma, Colin Hockings, W Douglas Fairlie, Erinna F Lee, Shenggen Yao, Adeline Y Robin, Brian J Smith,[...]. Cell 2013
376
9

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics.
Anthony Letai, Michael C Bassik, Loren D Walensky, Mia D Sorcinelli, Solly Weiler, Stanley J Korsmeyer. Cancer Cell 2002
9

The BCL-2 protein family: opposing activities that mediate cell death.
Richard J Youle, Andreas Strasser. Nat Rev Mol Cell Biol 2008
9

Programmed anuclear cell death delimits platelet life span.
Kylie D Mason, Marina R Carpinelli, Jamie I Fletcher, Janelle E Collinge, Adrienne A Hilton, Sarah Ellis, Priscilla N Kelly, Paul G Ekert, Donald Metcalf, Andrew W Roberts,[...]. Cell 2007
698
9

BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program.
Decheng Ren, Ho-Chou Tu, Hyungjin Kim, Gary X Wang, Gregory R Bean, Osamu Takeuchi, John R Jeffers, Gerard P Zambetti, James J-D Hsieh, Emily H-Y Cheng. Science 2010
342
9


Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis.
X M Yin, K Wang, A Gross, Y Zhao, S Zinkel, B Klocke, K A Roth, S J Korsmeyer. Nature 1999
816
8

Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.
David A Hildeman, Yanan Zhu, Thomas C Mitchell, Philippe Bouillet, Andreas Strasser, John Kappler, Philippa Marrack. Immunity 2002
452
8

RIP3 mediates the embryonic lethality of caspase-8-deficient mice.
William J Kaiser, Jason W Upton, Alyssa B Long, Devon Livingston-Rosanoff, Lisa P Daley-Bauer, Razqallah Hakem, Tamara Caspary, Edward S Mocarski. Nature 2011
687
8

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.
P Li, D Nijhawan, I Budihardjo, S M Srinivasula, M Ahmad, E S Alnemri, X Wang. Cell 1997
8

Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane.
Katelyn L O'Neill, Kai Huang, Jingjing Zhang, Yi Chen, Xu Luo. Genes Dev 2016
175
8

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.
Tomomi Kuwana, Lisa Bouchier-Hayes, Jerry E Chipuk, Christine Bonzon, Barbara A Sullivan, Douglas R Green, Donald D Newmeyer. Mol Cell 2005
912
8

ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor.
Christin Tse, Alexander R Shoemaker, Jessica Adickes, Mark G Anderson, Jun Chen, Sha Jin, Eric F Johnson, Kennan C Marsh, Michael J Mitten, Paul Nimmer,[...]. Cancer Res 2008
8

An inhibitor of Bcl-2 family proteins induces regression of solid tumours.
Tilman Oltersdorf, Steven W Elmore, Alexander R Shoemaker, Robert C Armstrong, David J Augeri, Barbara A Belli, Milan Bruncko, Thomas L Deckwerth, Jurgen Dinges, Philip J Hajduk,[...]. Nature 2005
8

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
Hyungjin Kim, Mubina Rafiuddin-Shah, Ho-Chou Tu, John R Jeffers, Gerard P Zambetti, James J-D Hsieh, Emily H-Y Cheng. Nat Cell Biol 2006
652
8

Bax-deficient mice with lymphoid hyperplasia and male germ cell death.
C M Knudson, K S Tung, W G Tourtellotte, G A Brown, S J Korsmeyer. Science 1995
8


Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK.
Francine F S Ke, Hannah K Vanyai, Angus D Cowan, Alex R D Delbridge, Lachlan Whitehead, Stephanie Grabow, Peter E Czabotar, Anne K Voss, Andreas Strasser. Cell 2018
93
8

The many roles of FAS receptor signaling in the immune system.
Andreas Strasser, Philipp J Jost, Shigekazu Nagata. Immunity 2009
599
7

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.
M Muzio, A M Chinnaiyan, F C Kischkel, K O'Rourke, A Shevchenko, J Ni, C Scaffidi, J D Bretz, M Zhang, R Gentz,[...]. Cell 1996
7

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis.
Andrew Oberst, Christopher P Dillon, Ricardo Weinlich, Laura L McCormick, Patrick Fitzgerald, Cristina Pop, Razq Hakem, Guy S Salvesen, Douglas R Green. Nature 2011
811
7

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome.
Vanessa S Marsden, Liam O'Connor, Lorraine A O'Reilly, John Silke, Donald Metcalf, Paul G Ekert, David C S Huang, Francesco Cecconi, Keisuke Kuida, Kevin J Tomaselli,[...]. Nature 2002
436
7

BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice.
F Ke, A Voss, J B Kerr, L A O'Reilly, L Tai, N Echeverry, P Bouillet, A Strasser, T Kaufmann. Cell Death Differ 2012
82
8

A unified model of mammalian BCL-2 protein family interactions at the mitochondria.
Fabien Llambi, Tudor Moldoveanu, Stephen W G Tait, Lisa Bouchier-Hayes, Jamshid Temirov, Laura L McCormick, Christopher P Dillon, Douglas R Green. Mol Cell 2011
392
7

Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis.
E M Michalak, E S Jansen, L Happo, M S Cragg, L Tai, G K Smyth, A Strasser, J M Adams, C L Scott. Cell Death Differ 2009
115
7

Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol.
Frank Edlich, Soojay Banerjee, Motoshi Suzuki, Megan M Cleland, Damien Arnoult, Chunxin Wang, Albert Neutzner, Nico Tjandra, Richard J Youle. Cell 2011
392
7

Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.
Hyungjin Kim, Ho-Chou Tu, Decheng Ren, Osamu Takeuchi, John R Jeffers, Gerard P Zambetti, James J-D Hsieh, Emily H-Y Cheng. Mol Cell 2009
428
7

Regulation of Bim in Health and Disease.
Ronit Vogt Sionov, Spiros A Vlahopoulos, Zvi Granot. Oncotarget 2015
111
7

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice.
J M Adams, A W Harris, C A Pinkert, L M Corcoran, W S Alexander, S Cory, R D Palmiter, R L Brinster. Nature 1985
7

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Lorenzo Galluzzi, Ilio Vitale, Stuart A Aaronson, John M Abrams, Dieter Adam, Patrizia Agostinis, Emad S Alnemri, Lucia Altucci, Ivano Amelio, David W Andrews,[...]. Cell Death Differ 2018
7

Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53.
Gemma L Kelly, Stephanie Grabow, Stefan P Glaser, Leah Fitzsimmons, Brandon J Aubrey, Toru Okamoto, Liz J Valente, Mikara Robati, Lin Tai, W Douglas Fairlie,[...]. Genes Dev 2014
123
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.