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Times Cited: 1214
Times Cited: 1214
Times Cited
Times Co-cited
Similarity
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy.
Peter E Czabotar, Guillaume Lessene, Andreas Strasser, Jerry M Adams. Nat Rev Mol Cell Biol 2014
Peter E Czabotar, Guillaume Lessene, Andreas Strasser, Jerry M Adams. Nat Rev Mol Cell Biol 2014
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p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa.
Andreas Villunger, Ewa M Michalak, Leigh Coultas, Franziska Müllauer, Gunther Böck, Michael J Ausserlechner, Jerry M Adams, Andreas Strasser. Science 2003
Andreas Villunger, Ewa M Michalak, Leigh Coultas, Franziska Müllauer, Gunther Böck, Michael J Ausserlechner, Jerry M Adams, Andreas Strasser. Science 2003
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The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.
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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes.
Philippe Bouillet, Jared F Purton, Dale I Godfrey, Li-Chen Zhang, Leigh Coultas, Hamsa Puthalakath, Marc Pellegrini, Suzanne Cory, Jerry M Adams, Andreas Strasser. Nature 2002
Philippe Bouillet, Jared F Purton, Dale I Godfrey, Li-Chen Zhang, Leigh Coultas, Hamsa Puthalakath, Marc Pellegrini, Suzanne Cory, Jerry M Adams, Andreas Strasser. Nature 2002
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Bim: a novel member of the Bcl-2 family that promotes apoptosis.
L O'Connor, A Strasser, L A O'Reilly, G Hausmann, J M Adams, S Cory, D C Huang. EMBO J 1998
L O'Connor, A Strasser, L A O'Reilly, G Hausmann, J M Adams, S Cory, D C Huang. EMBO J 1998
13
ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets.
Andrew J Souers, Joel D Leverson, Erwin R Boghaert, Scott L Ackler, Nathaniel D Catron, Jun Chen, Brian D Dayton, Hong Ding, Sari H Enschede, Wayne J Fairbrother,[...]. Nat Med 2013
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Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells.
Anselm Enders, Philippe Bouillet, Hamsa Puthalakath, Yuekang Xu, David M Tarlinton, Andreas Strasser. J Exp Med 2003
Anselm Enders, Philippe Bouillet, Hamsa Puthalakath, Yuekang Xu, David M Tarlinton, Andreas Strasser. J Exp Med 2003
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The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models.
András Kotschy, Zoltán Szlavik, James Murray, James Davidson, Ana Leticia Maragno, Gaëtane Le Toumelin-Braizat, Maïa Chanrion, Gemma L Kelly, Jia-Nan Gong, Donia M Moujalled,[...]. Nature 2016
András Kotschy, Zoltán Szlavik, James Murray, James Davidson, Ana Leticia Maragno, Gaëtane Le Toumelin-Braizat, Maïa Chanrion, Gemma L Kelly, Jia-Nan Gong, Donia M Moujalled,[...]. Nature 2016
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Bim is a suppressor of Myc-induced mouse B cell leukemia.
Alexander Egle, Alan W Harris, Philippe Bouillet, Suzanne Cory. Proc Natl Acad Sci U S A 2004
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Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia.
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Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells.
D L Vaux, S Cory, J M Adams. Nature 1988
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Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function.
Lin Chen, Simon N Willis, Andrew Wei, Brian J Smith, Jamie I Fletcher, Mark G Hinds, Peter M Colman, Catherine L Day, Jerry M Adams, David C S Huang. Mol Cell 2005
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Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics.
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Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease.
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Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice.
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XIAP discriminates between type I and type II FAS-induced apoptosis.
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ER stress triggers apoptosis by activating BH3-only protein Bim.
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Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.
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bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship.
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Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis.
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Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics.
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The BCL-2 protein family: opposing activities that mediate cell death.
Richard J Youle, Andreas Strasser. Nat Rev Mol Cell Biol 2008
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Programmed anuclear cell death delimits platelet life span.
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BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program.
Decheng Ren, Ho-Chou Tu, Hyungjin Kim, Gary X Wang, Gregory R Bean, Osamu Takeuchi, John R Jeffers, Gerard P Zambetti, James J-D Hsieh, Emily H-Y Cheng. Science 2010
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9
The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex.
H Puthalakath, D C Huang, L A O'Reilly, S M King, A Strasser. Mol Cell 1999
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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis.
X M Yin, K Wang, A Gross, Y Zhao, S Zinkel, B Klocke, K A Roth, S J Korsmeyer. Nature 1999
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8
Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.
David A Hildeman, Yanan Zhu, Thomas C Mitchell, Philippe Bouillet, Andreas Strasser, John Kappler, Philippa Marrack. Immunity 2002
David A Hildeman, Yanan Zhu, Thomas C Mitchell, Philippe Bouillet, Andreas Strasser, John Kappler, Philippa Marrack. Immunity 2002
8
RIP3 mediates the embryonic lethality of caspase-8-deficient mice.
William J Kaiser, Jason W Upton, Alyssa B Long, Devon Livingston-Rosanoff, Lisa P Daley-Bauer, Razqallah Hakem, Tamara Caspary, Edward S Mocarski. Nature 2011
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8
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.
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8
Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane.
Katelyn L O'Neill, Kai Huang, Jingjing Zhang, Yi Chen, Xu Luo. Genes Dev 2016
Katelyn L O'Neill, Kai Huang, Jingjing Zhang, Yi Chen, Xu Luo. Genes Dev 2016
8
BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.
Tomomi Kuwana, Lisa Bouchier-Hayes, Jerry E Chipuk, Christine Bonzon, Barbara A Sullivan, Douglas R Green, Donald D Newmeyer. Mol Cell 2005
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ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor.
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8
An inhibitor of Bcl-2 family proteins induces regression of solid tumours.
Tilman Oltersdorf, Steven W Elmore, Alexander R Shoemaker, Robert C Armstrong, David J Augeri, Barbara A Belli, Milan Bruncko, Thomas L Deckwerth, Jurgen Dinges, Philip J Hajduk,[...]. Nature 2005
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8
Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
Hyungjin Kim, Mubina Rafiuddin-Shah, Ho-Chou Tu, John R Jeffers, Gerard P Zambetti, James J-D Hsieh, Emily H-Y Cheng. Nat Cell Biol 2006
Hyungjin Kim, Mubina Rafiuddin-Shah, Ho-Chou Tu, John R Jeffers, Gerard P Zambetti, James J-D Hsieh, Emily H-Y Cheng. Nat Cell Biol 2006
8
Bax-deficient mice with lymphoid hyperplasia and male germ cell death.
C M Knudson, K S Tung, W G Tourtellotte, G A Brown, S J Korsmeyer. Science 1995
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Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair.
D J Veis, C M Sorenson, J R Shutter, S J Korsmeyer. Cell 1993
D J Veis, C M Sorenson, J R Shutter, S J Korsmeyer. Cell 1993
8
Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK.
Francine F S Ke, Hannah K Vanyai, Angus D Cowan, Alex R D Delbridge, Lachlan Whitehead, Stephanie Grabow, Peter E Czabotar, Anne K Voss, Andreas Strasser. Cell 2018
Francine F S Ke, Hannah K Vanyai, Angus D Cowan, Alex R D Delbridge, Lachlan Whitehead, Stephanie Grabow, Peter E Czabotar, Anne K Voss, Andreas Strasser. Cell 2018
8
The many roles of FAS receptor signaling in the immune system.
Andreas Strasser, Philipp J Jost, Shigekazu Nagata. Immunity 2009
Andreas Strasser, Philipp J Jost, Shigekazu Nagata. Immunity 2009
7
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.
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7
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis.
Andrew Oberst, Christopher P Dillon, Ricardo Weinlich, Laura L McCormick, Patrick Fitzgerald, Cristina Pop, Razq Hakem, Guy S Salvesen, Douglas R Green. Nature 2011
Andrew Oberst, Christopher P Dillon, Ricardo Weinlich, Laura L McCormick, Patrick Fitzgerald, Cristina Pop, Razq Hakem, Guy S Salvesen, Douglas R Green. Nature 2011
7
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome.
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7
BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice.
F Ke, A Voss, J B Kerr, L A O'Reilly, L Tai, N Echeverry, P Bouillet, A Strasser, T Kaufmann. Cell Death Differ 2012
F Ke, A Voss, J B Kerr, L A O'Reilly, L Tai, N Echeverry, P Bouillet, A Strasser, T Kaufmann. Cell Death Differ 2012
8
A unified model of mammalian BCL-2 protein family interactions at the mitochondria.
Fabien Llambi, Tudor Moldoveanu, Stephen W G Tait, Lisa Bouchier-Hayes, Jamshid Temirov, Laura L McCormick, Christopher P Dillon, Douglas R Green. Mol Cell 2011
Fabien Llambi, Tudor Moldoveanu, Stephen W G Tait, Lisa Bouchier-Hayes, Jamshid Temirov, Laura L McCormick, Christopher P Dillon, Douglas R Green. Mol Cell 2011
7
Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis.
E M Michalak, E S Jansen, L Happo, M S Cragg, L Tai, G K Smyth, A Strasser, J M Adams, C L Scott. Cell Death Differ 2009
E M Michalak, E S Jansen, L Happo, M S Cragg, L Tai, G K Smyth, A Strasser, J M Adams, C L Scott. Cell Death Differ 2009
7
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol.
Frank Edlich, Soojay Banerjee, Motoshi Suzuki, Megan M Cleland, Damien Arnoult, Chunxin Wang, Albert Neutzner, Nico Tjandra, Richard J Youle. Cell 2011
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7
Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.
Hyungjin Kim, Ho-Chou Tu, Decheng Ren, Osamu Takeuchi, John R Jeffers, Gerard P Zambetti, James J-D Hsieh, Emily H-Y Cheng. Mol Cell 2009
Hyungjin Kim, Ho-Chou Tu, Decheng Ren, Osamu Takeuchi, John R Jeffers, Gerard P Zambetti, James J-D Hsieh, Emily H-Y Cheng. Mol Cell 2009
7
Regulation of Bim in Health and Disease.
Ronit Vogt Sionov, Spiros A Vlahopoulos, Zvi Granot. Oncotarget 2015
Ronit Vogt Sionov, Spiros A Vlahopoulos, Zvi Granot. Oncotarget 2015
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The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice.
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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Lorenzo Galluzzi, Ilio Vitale, Stuart A Aaronson, John M Abrams, Dieter Adam, Patrizia Agostinis, Emad S Alnemri, Lucia Altucci, Ivano Amelio, David W Andrews,[...]. Cell Death Differ 2018
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7
Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53.
Gemma L Kelly, Stephanie Grabow, Stefan P Glaser, Leah Fitzsimmons, Brandon J Aubrey, Toru Okamoto, Liz J Valente, Mikara Robati, Lin Tai, W Douglas Fairlie,[...]. Genes Dev 2014
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7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.