A citation-based method for searching scientific literature

J S Palmer, D L Duffy, N F Box, J F Aitken, L E O'Gorman, A C Green, N K Hayward, N G Martin, R A Sturm. Am J Hum Genet 2000
Times Cited: 385







List of co-cited articles
1054 articles co-cited >1



Times Cited
  Times     Co-cited
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Melanocortin 1 receptor (MC1R) gene variants are associated with an increased risk for cutaneous melanoma which is largely independent of skin type and hair color.
C Kennedy, J ter Huurne, M Berkhout, N Gruis, M Bastiaens, W Bergman, R Willemze, J N Bavinck. J Invest Dermatol 2001
293
45

Characterization of melanocyte stimulating hormone receptor variant alleles in twins with red hair.
N F Box, J R Wyeth, L E O'Gorman, N G Martin, R A Sturm. Hum Mol Genet 1997
261
30

MC1R variants, melanoma and red hair color phenotype: a meta-analysis.
Sara Raimondi, Francesco Sera, Sara Gandini, Simona Iodice, Saverio Caini, Patrick Maisonneuve, Maria Concetta Fargnoli. Int J Cancer 2008
233
30

An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background.
Devarati Mitra, Xi Luo, Ann Morgan, Jin Wang, Mai P Hoang, Jennifer Lo, Candace R Guerrero, Jochen K Lennerz, Martin C Mihm, Jennifer A Wargo,[...]. Nature 2012
277
28

alpha-Melanocortin and endothelin-1 activate antiapoptotic pathways and reduce DNA damage in human melanocytes.
Ana Luisa Kadekaro, Renny Kavanagh, Hiromi Kanto, Silva Terzieva, Jennifer Hauser, Nobuhiko Kobayashi, Sandy Schwemberger, James Cornelius, George Babcock, Howard G Shertzer,[...]. Cancer Res 2005
193
23

The Asp84Glu variant of the melanocortin 1 receptor (MC1R) is associated with melanoma.
P Valverde, E Healy, S Sikkink, F Haldane, A J Thody, A Carothers, I J Jackson, J L Rees. Hum Mol Genet 1996
242
23

Melanocortin-1 receptor structure and functional regulation.
José C García-Borrón, Berta L Sánchez-Laorden, Celia Jiménez-Cervantes. Pigment Cell Res 2005
237
22

Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning.
John A D'Orazio, Tetsuji Nobuhisa, Rutao Cui, Michelle Arya, Malinda Spry, Kazumasa Wakamatsu, Vivien Igras, Takahiro Kunisada, Scott R Granter, Emi K Nishimura,[...]. Nature 2006
238
22

Interactive effects of MC1R and OCA2 on melanoma risk phenotypes.
David L Duffy, Neil F Box, Wei Chen, James S Palmer, Grant W Montgomery, Michael R James, Nicholas K Hayward, Nicholas G Martin, Richard A Sturm. Hum Mol Genet 2004
193
21

Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation.
Ana Luisa Kadekaro, Sancy Leachman, Renny J Kavanagh, Viki Swope, Pamela Cassidy, Dorothy Supp, Maureen Sartor, Sandy Schwemberger, George Babcock, Kazumasa Wakamatsu,[...]. FASEB J 2010
96
21

Melanocortin 1 receptor variants in an Irish population.
R Smith, E Healy, S Siddiqui, N Flanagan, P M Steijlen, I Rosdahl, J P Jacques, S Rogers, R Turner, I J Jackson,[...]. J Invest Dermatol 1998
201
21

MC1R, ASIP, and DNA repair in sporadic and familial melanoma in a Mediterranean population.
Maria Teresa Landi, Peter A Kanetsky, Shirley Tsang, Bert Gold, David Munroe, Timothy Rebbeck, Jennifer Swoyer, Monica Ter-Minassian, Mohammad Hedayati, Lawrence Grossman,[...]. J Natl Cancer Inst 2005
134
20

alpha-Melanocyte-stimulating hormone protects from ultraviolet radiation-induced apoptosis and DNA damage.
Markus Böhm, Ilka Wolff, Thomas E Scholzen, Samantha J Robinson, Eugene Healy, Thomas A Luger, Thomas Schwarz, Agatha Schwarz. J Biol Chem 2005
165
19

Does MC1R genotype convey information about melanoma risk beyond risk phenotypes?
Peter A Kanetsky, Saarene Panossian, David E Elder, DuPont Guerry, Michael E Ming, Lynn Schuchter, Timothy R Rebbeck. Cancer 2010
74
25

MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutations.
N F Box, D L Duffy, W Chen, M Stark, N G Martin, R A Sturm, N K Hayward. Am J Hum Genet 2001
220
19

Alpha-melanocyte-stimulating hormone suppresses oxidative stress through a p53-mediated signaling pathway in human melanocytes.
Ana Luisa Kadekaro, Juping Chen, Jennifer Yang, Shuna Chen, Joshua Jameson, Viki B Swope, Tan Cheng, Madhavi Kadakia, Zalfa Abdel-Malek. Mol Cancer Res 2012
90
21

alpha-MSH activates immediate defense responses to UV-induced oxidative stress in human melanocytes.
Xiuzu Song, Nicole Mosby, Jennifer Yang, Aie Xu, Zalfa Abdel-Malek, Ana Luisa Kadekaro. Pigment Cell Melanoma Res 2009
112
18

Melanocortin 1 receptor and risk of cutaneous melanoma: a meta-analysis and estimates of population burden.
Patricia F Williams, Catherine M Olsen, Nicholas K Hayward, David C Whiteman. Int J Cancer 2011
85
21

Human melanocortin 1 receptor variants, receptor function and melanocyte response to UV radiation.
M Cathy Scott, Kazumasa Wakamatsu, Shosuke Ito, Ana Luisa Kadekaro, Nobuhiko Kobayashi, Joanna Groden, Renny Kavanagh, Takako Takakuwa, Victoria Virador, Vincent J Hearing,[...]. J Cell Sci 2002
145
18

Comprehensive evaluation of allele frequency differences of MC1R variants across populations.
Meg R Gerstenblith, Alisa M Goldstein, Maria Concetta Fargnoli, Ketty Peris, Maria Teresa Landi. Hum Mutat 2007
116
17

Population-based study of natural variation in the melanocortin-1 receptor gene and melanoma.
Peter A Kanetsky, Timothy R Rebbeck, Amanda J Hummer, Saarene Panossian, Bruce K Armstrong, Anne Kricker, Loraine D Marrett, Robert C Millikan, Stephen B Gruber, Hoda Anton Culver,[...]. Cancer Res 2006
96
16

A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma.
Satoru Yokoyama, Susan L Woods, Glen M Boyle, Lauren G Aoude, Stuart MacGregor, Victoria Zismann, Michael Gartside, Anne E Cust, Rizwan Haq, Mark Harland,[...]. Nature 2011
277
16

A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma.
Corine Bertolotto, Fabienne Lesueur, Sandy Giuliano, Thomas Strub, Mahaut de Lichy, Karine Bille, Philippe Dessen, Benoit d'Hayer, Hamida Mohamdi, Audrey Remenieras,[...]. Nature 2011
326
16

Melanocortin-1 receptor gene variants determine the risk of nonmelanoma skin cancer independently of fair skin and red hair.
M T Bastiaens, J A ter Huurne, C Kielich, N A Gruis, R G Westendorp, B J Vermeer, J N Bavinck. Am J Hum Genet 2001
181
16

Central role of p53 in the suntan response and pathologic hyperpigmentation.
Rutao Cui, Hans R Widlund, Erez Feige, Jennifer Y Lin, Dara L Wilensky, Viven E Igras, John D'Orazio, Claire Y Fung, Carl F Schanbacher, Scott R Granter,[...]. Cell 2007
401
16

alpha-MSH tripeptide analogs activate the melanocortin 1 receptor and reduce UV-induced DNA damage in human melanocytes.
Zalfa A Abdel-Malek, Andrew Ruwe, Renny Kavanagh-Starner, Ana Luisa Kadekaro, Viki Swope, Carrie Haskell-Luevano, Leonid Koikov, James J Knittel. Pigment Cell Melanoma Res 2009
56
28

Germline MC1R status influences somatic mutation burden in melanoma.
Carla Daniela Robles-Espinoza, Nicola D Roberts, Shuyang Chen, Finbarr P Leacy, Ludmil B Alexandrov, Natapol Pornputtapong, Ruth Halaban, Michael Krauthammer, Rutao Cui, D Timothy Bishop,[...]. Nat Commun 2016
76
21

MC1R germline variants confer risk for BRAF-mutant melanoma.
Maria Teresa Landi, Jürgen Bauer, Ruth M Pfeiffer, David E Elder, Benjamin Hulley, Paola Minghetti, Donato Calista, Peter A Kanetsky, Daniel Pinkel, Boris C Bastian. Science 2006
238
15

Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human melanocytes.
Jennifer E Hauser, Ana Luisa Kadekaro, Renny J Kavanagh, Kazumasa Wakamatsu, Silva Terzieva, Sandy Schwemberger, George Babcock, M B Rao, Shosuke Ito, Zalfa A Abdel-Malek. Pigment Cell Res 2006
95
15

Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk.
Kimberley A Beaumont, Richard A Newton, Darren J Smit, J Helen Leonard, Jennifer L Stow, Richard A Sturm. Hum Mol Genet 2005
124
15

A landscape of driver mutations in melanoma.
Eran Hodis, Ian R Watson, Gregory V Kryukov, Stefan T Arold, Marcin Imielinski, Jean-Philippe Theurillat, Elizabeth Nickerson, Daniel Auclair, Liren Li, Chelsea Place,[...]. Cell 2012
15

MC1R variants increased the risk of sporadic cutaneous melanoma in darker-pigmented Caucasians: a pooled-analysis from the M-SKIP project.
Elena Pasquali, José C García-Borrón, Maria Concetta Fargnoli, Sara Gandini, Patrick Maisonneuve, Vincenzo Bagnardi, Claudia Specchia, Fan Liu, Manfred Kayser, Tamar Nijsten,[...]. Int J Cancer 2015
64
23

Multiple pigmentation gene polymorphisms account for a substantial proportion of risk of cutaneous malignant melanoma.
David L Duffy, Zhen Z Zhao, Richard A Sturm, Nicholas K Hayward, Nicholas G Martin, Grant W Montgomery. J Invest Dermatol 2010
130
14

Receptor function, dominant negative activity and phenotype correlations for MC1R variant alleles.
Kimberley A Beaumont, Sri N Shekar, Richard A Newton, Michael R James, Jennifer L Stow, David L Duffy, Richard A Sturm. Hum Mol Genet 2007
126
14

Evidence for variable selective pressures at MC1R.
R M Harding, E Healy, A J Ray, N S Ellis, N Flanagan, C Todd, C Dixon, A Sajantila, I J Jackson, M A Birch-Machin,[...]. Am J Hum Genet 2000
259
14

The cloning of a family of genes that encode the melanocortin receptors.
K G Mountjoy, L S Robbins, M T Mortrud, R D Cone. Science 1992
14

Significance of the melanocortin 1 receptor in the DNA damage response of human melanocytes to ultraviolet radiation.
Viki Swope, Christina Alexander, Renny Starner, Sandy Schwemberger, George Babcock, Zalfa A Abdel-Malek. Pigment Cell Melanoma Res 2014
47
29

Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma.
L Zuo, J Weger, Q Yang, A M Goldstein, M A Tucker, G J Walker, N Hayward, N C Dracopoli. Nat Genet 1996
611
13

Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function.
L S Robbins, J H Nadeau, K R Johnson, M A Kelly, L Roselli-Rehfuss, E Baack, K G Mountjoy, R D Cone. Cell 1993
685
13


Defining MC1R regulation in human melanocytes by its agonist α-melanocortin and antagonists agouti signaling protein and β-defensin 3.
Viki B Swope, Joshua A Jameson, Kevin L McFarland, Dorothy M Supp, William E Miller, Dennis W McGraw, Mira A Patel, Matthew A Nix, Glenn L Millhauser, George F Babcock,[...]. J Invest Dermatol 2012
64
20

MC1R is a potent regulator of PTEN after UV exposure in melanocytes.
Juxiang Cao, Lixin Wan, Elke Hacker, Xiangpeng Dai, Stefania Lenna, Celia Jimenez-Cervantes, Yongjun Wang, Nick R Leslie, George X Xu, Hans R Widlund,[...]. Mol Cell 2013
97
13

Genome-wide association study identifies three loci associated with melanoma risk.
D Timothy Bishop, Florence Demenais, Mark M Iles, Mark Harland, John C Taylor, Eve Corda, Juliette Randerson-Moor, Joanne F Aitken, Marie-Francoise Avril, Esther Azizi,[...]. Nat Genet 2009
333
12

Loss of function mutations of the human melanocortin 1 receptor are common and are associated with red hair.
H B Schiöth, S R Phillips, R Rudzish, M A Birch-Machin, J E Wikberg, J L Rees. Biochem Biophys Res Commun 1999
190
12

Genome-wide association study identifies novel loci predisposing to cutaneous melanoma.
Christopher I Amos, Li-E Wang, Jeffrey E Lee, Jeffrey E Gershenwald, Wei V Chen, Shenying Fang, Roman Kosoy, Mingfeng Zhang, Abrar A Qureshi, Selina Vattathil,[...]. Hum Mol Genet 2011
152
12

Melanocortin receptor-1 gene polymorphisms and the risk of cutaneous melanoma in a low-risk southern European population.
Alexander J Stratigos, Gerasimos Dimisianos, Vasiliki Nikolaou, Mirto Poulou, Vana Sypsa, Irene Stefanaki, Othon Papadopoulos, Dorothea Polydorou, Michaela Plaka, Eleftheria Christofidou,[...]. J Invest Dermatol 2006
74
16

MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation.
Jose C García-Borrón, Zalfa Abdel-Malek, Celia Jiménez-Cervantes. Pigment Cell Melanoma Res 2014
103
12

POT1 loss-of-function variants predispose to familial melanoma.
Carla Daniela Robles-Espinoza, Mark Harland, Andrew J Ramsay, Lauren G Aoude, Víctor Quesada, Zhihao Ding, Karen A Pooley, Antonia L Pritchard, Jessamy C Tiffen, Mia Petljak,[...]. Nat Genet 2014
221
12

PKA-mediated phosphorylation of ATR promotes recruitment of XPA to UV-induced DNA damage.
Stuart G Jarrett, Erin M Wolf Horrell, Perry A Christian, Jillian C Vanover, Mary C Boulanger, Yue Zou, John A D'Orazio. Mol Cell 2014
69
17


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.