A citation-based method for searching scientific literature

S Himpel, W Tegge, R Frank, S Leder, H G Joost, W Becker. J Biol Chem 2000
Times Cited: 181







List of co-cited articles
867 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



minibrain: a new protein kinase family involved in postembryonic neurogenesis in Drosophila.
F Tejedor, X R Zhu, E Kaltenbach, A Ackermann, A Baumann, I Canal, M Heisenberg, K F Fischbach, O Pongs. Neuron 1995
299
27

Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs.
Pamela A Lochhead, Gary Sibbet, Nick Morrice, Vaughn Cleghon. Cell 2005
214
24



Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.
X Altafaj, M Dierssen, C Baamonde, E Martí, J Visa, J Guimerà, M Oset, J R González, J Flórez, C Fillat,[...]. Hum Mol Genet 2001
291
20

NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.
Joseph R Arron, Monte M Winslow, Alberto Polleri, Ching-Pin Chang, Hai Wu, Xin Gao, Joel R Neilson, Lei Chen, Jeremy J Heit, Seung K Kim,[...]. Nature 2006
498
19

Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice.
Vassiliki Fotaki, Mara Dierssen, Soledad Alcántara, Salvador Martínez, Eulàlia Martí, Caty Casas, Joana Visa, Eduardo Soriano, Xavier Estivill, Maria L Arbonés. Mol Cell Biol 2002
238
19

Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation.
Nora Göckler, Guillermo Jofre, Chrisovalantis Papadopoulos, Ulf Soppa, Francisco J Tejedor, Walter Becker. FEBS J 2009
166
19

The selectivity of protein kinase inhibitors: a further update.
Jenny Bain, Lorna Plater, Matt Elliott, Natalia Shpiro, C James Hastie, Hilary McLauchlan, Iva Klevernic, J Simon C Arthur, Dario R Alessi, Philip Cohen. Biochem J 2007
18


Function and regulation of Dyrk1A: towards understanding Down syndrome.
Joongkyu Park, Woo-Joo Song, Kwang Chul Chung. Cell Mol Life Sci 2009
136
17

Trisomy-driven overexpression of DYRK1A kinase in the brain of subjects with Down syndrome.
Wieslaw K Dowjat, Tatyana Adayev, Izabela Kuchna, Krzysztof Nowicki, Sonia Palminiello, Yu Wen Hwang, Jerzy Wegiel. Neurosci Lett 2007
127
16

Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII.
H Kentrup, W Becker, J Heukelbach, A Wilmes, A Schürmann, C Huppertz, H Kainulainen, H G Joost. J Biol Chem 1996
206
16

Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A.
S Himpel, P Panzer, K Eirmbter, H Czajkowska, M Sayed, L C Packman, T Blundell, H Kentrup, J Grötzinger, H G Joost,[...]. Biochem J 2001
123
16


Truncation of the Down syndrome candidate gene DYRK1A in two unrelated patients with microcephaly.
Rikke S Møller, Sabine Kübart, Maria Hoeltzenbein, Babett Heye, Ida Vogel, Christian P Hansen, Corinna Menzel, Reinhard Ullmann, Niels Tommerup, Hans-Hilger Ropers,[...]. Am J Hum Genet 2008
117
16

Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition.
Meera Soundararajan, Annette K Roos, Pavel Savitsky, Panagis Filippakopoulos, Arminja N Kettenbach, Jesper V Olsen, Scott A Gerber, Jeyanthy Eswaran, Stefan Knapp, Jonathan M Elkins. Structure 2013
97
16

A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT.
Yousang Gwack, Sonia Sharma, Julie Nardone, Bogdan Tanasa, Alina Iuga, Sonal Srikanth, Heidi Okamura, Diana Bolton, Stefan Feske, Patrick G Hogan,[...]. Nature 2006
288
15

A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region.
J Guimerá, C Casas, C Pucharcòs, A Solans, A Domènech, A M Planas, J Ashley, M Lovett, X Estivill, M A Pritchard. Hum Mol Genet 1996
172
15

The protein kinase complement of the human genome.
G Manning, D B Whyte, R Martinez, T Hunter, S Sudarsanam. Science 2002
15

Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A.
Yasushi Ogawa, Yosuke Nonaka, Toshiyasu Goto, Eriko Ohnishi, Toshiyuki Hiramatsu, Isao Kii, Miyo Yoshida, Teikichi Ikura, Hiroshi Onogi, Hiroshi Shibuya,[...]. Nat Commun 2010
178
15

DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease.
Soo-Ryoon Ryoo, Hey Kyeong Jeong, Chinzorig Radnaabazar, Jin-Ju Yoo, Hyun-Jeong Cho, Hye-Won Lee, In-Sook Kim, Young-Hee Cheon, Young Soo Ahn, Sul-Hee Chung,[...]. J Biol Chem 2007
171
14

DYRK1A BAC transgenic mice show altered synaptic plasticity with learning and memory defects.
Kyoung-Jin Ahn, Hey Kyeong Jeong, Han-Saem Choi, Soo-Ryoon Ryoo, Yeon Ju Kim, Jun-Seo Goo, Se-Young Choi, Jung-Soo Han, Ilho Ha, Woo-Joo Song. Neurobiol Dis 2006
155
14

DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding.
Mónica Alvarez, Xavier Altafaj, Sergi Aranda, Susana de la Luna. Mol Biol Cell 2007
52
26

MNB/DYRK1A as a multiple regulator of neuronal development.
Francisco J Tejedor, Barbara Hämmerle. FEBS J 2011
146
14

Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system.
Eulàlia Martí, Xavier Altafaj, Mara Dierssen, Susana de la Luna, Vassiliki Fotaki, Mónica Alvarez, Mercè Pérez-Riba, Isidro Ferrer, Xavier Estivill. Brain Res 2003
96
13




Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells.
Joongkyu Park, Yohan Oh, Lang Yoo, Min-Su Jung, Woo-Joo Song, Sang-Hun Lee, Hyemyung Seo, Kwang Chul Chung. J Biol Chem 2010
83
14

DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly.
Larisa Litovchick, Laurence A Florens, Selene K Swanson, Michael P Washburn, James A DeCaprio. Genes Dev 2011
176
12


The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease.
Ryo Kimura, Kouzin Kamino, Mitsuko Yamamoto, Aidaralieva Nuripa, Tomoyuki Kida, Hiroaki Kazui, Ryota Hashimoto, Toshihisa Tanaka, Takashi Kudo, Hidehisa Yamagata,[...]. Hum Mol Genet 2007
181
11

Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome.
Fei Liu, Zhihou Liang, Jerzy Wegiel, Yu-Wen Hwang, Khalid Iqbal, Inge Grundke-Iqbal, Narayan Ramakrishna, Cheng-Xin Gong. FASEB J 2008
160
11

The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development.
Ariadna Laguna, Sergi Aranda, María José Barallobre, Rima Barhoum, Eduardo Fernández, Vassiliki Fotaki, Jean Maurice Delabar, Susana de la Luna, Pedro de la Villa, Maria L Arbonés. Dev Cell 2008
88
12


Activation, regulation, and inhibition of DYRK1A.
Walter Becker, Wolfgang Sippl. FEBS J 2011
140
11

Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome "critical region".
W J Song, L R Sternberg, C Kasten-Sportès, M L Keuren, S H Chung, A C Slack, D E Miller, T W Glover, P W Chiang, L Lou,[...]. Genomics 1996
142
10

Dyrk1A overexpression in immortalized hippocampal cells produces the neuropathological features of Down syndrome.
Joongkyu Park, Eun Jin Yang, Joo Heon Yoon, Kwang Chul Chung. Mol Cell Neurosci 2007
46
21

Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome.
D J Smith, M E Stevens, S P Sudanagunta, R T Bronson, M Makhinson, A M Watabe, T J O'Dell, J Fung, H U Weier, J F Cheng,[...]. Nat Genet 1997
247
10

Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.
Soo-Ryoon Ryoo, Hyun-Jeong Cho, Hye-Won Lee, Hey Kyeong Jeong, Chinzorig Radnaabazar, Yeun-Soo Kim, Min-Jeong Kim, Mi-Young Son, Hyemyung Seo, Sul-Hee Chung,[...]. J Neurochem 2008
137
10

Phosphorylation of amphiphysin I by minibrain kinase/dual-specificity tyrosine phosphorylation-regulated kinase, a kinase implicated in Down syndrome.
Noriko Murakami, Wen Xie, Renne Chen Lu, Mo-Chou Chen-Hwang, Andrzej Wieraszko, Yu Wen Hwang. J Biol Chem 2006
51
19

A rapid method for determining protein kinase phosphorylation specificity.
Jessica E Hutti, Emily T Jarrell, James D Chang, Derek W Abbott, Peter Storz, Alex Toker, Lewis C Cantley, Benjamin E Turk. Nat Methods 2004
263
10

DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage.
Naoe Taira, Keishi Nihira, Tomoko Yamaguchi, Yoshio Miki, Kiyotsugu Yoshida. Mol Cell 2007
210
10


Nonprimed and DYRK1A-primed GSK3 beta-phosphorylation sites on MAP1B regulate microtubule dynamics in growing axons.
Timothy M E Scales, Shen Lin, Michaela Kraus, Robert G Goold, Phillip R Gordon-Weeks. J Cell Sci 2009
68
14

Mechanism of dual specificity kinase activity of DYRK1A.
Agnes Walte, Katharina Rüben, Ruth Birner-Gruenberger, Christian Preisinger, Simone Bamberg-Lemper, Nikolaus Hilz, Franz Bracher, Walter Becker. FEBS J 2013
45
22

The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site.
Y L Woods, G Rena, N Morrice, A Barthel, W Becker, S Guo, T G Unterman, P Cohen. Biochem J 2001
211
9

Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with Down syndrome and in Ts65Dn mice.
Andrea Contestabile, Tatiana Fila, Claudio Ceccarelli, Paola Bonasoni, Laura Bonapace, Donatella Santini, Renata Bartesaghi, Elisabetta Ciani. Hippocampus 2007
191
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.