A citation-based method for searching scientific literature

K W Gripp, D Wotton, M C Edwards, E Roessler, L Ades, P Meinecke, A Richieri-Costa, E H Zackai, J Massagué, M Muenke, S J Elledge. Nat Genet 2000
Times Cited: 300







List of co-cited articles
773 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



A Smad transcriptional corepressor.
D Wotton, R S Lo, S Lee, J Massagué. Cell 1999
448
31

Mutations in the human Sonic Hedgehog gene cause holoprosencephaly.
E Roessler, E Belloni, K Gaudenz, P Jay, P Berta, S W Scherer, L C Tsui, M Muenke. Nat Genet 1996
841
30

Mutations in the homeodomain of the human SIX3 gene cause holoprosencephaly.
D E Wallis, E Roessler, U Hehr, L Nanni, T Wiltshire, A Richieri-Costa, G Gillessen-Kaesbach, E H Zackai, J Rommens, M Muenke. Nat Genet 1999
283
27

Holoprosencephaly due to mutations in ZIC2, a homologue of Drosophila odd-paired.
S A Brown, D Warburton, L Y Brown, C Y Yu, E R Roeder, S Stengel-Rutkowski, R C Hennekam, M Muenke. Nat Genet 1998
365
26

Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features.
Erich Roessler, Yang-Zhu Du, Jose L Mullor, Esther Casas, William P Allen, Gabriele Gillessen-Kaesbach, Elizabeth R Roeder, Jeffrey E Ming, Ariel Ruiz i Altaba, Maximilian Muenke. Proc Natl Acad Sci U S A 2003
235
24

TGIF inhibits retinoid signaling.
Laurent Bartholin, Shannon E Powers, Tiffany A Melhuish, Samuel Lasse, Michael Weinstein, David Wotton. Mol Cell Biol 2006
89
24

Mutations in PATCHED-1, the receptor for SONIC HEDGEHOG, are associated with holoprosencephaly.
Jeffrey E Ming, Michelle E Kaupas, Erich Roessler, Han G Brunner, Mahin Golabi, Mustafa Tekin, Robert F Stratton, Eva Sujansky, Sherri J Bale, Maximilian Muenke. Hum Genet 2002
158
21

Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.
Kenichiro Taniguchi, Anoush E Anderson, Ann E Sutherland, David Wotton. PLoS Genet 2012
56
37

Functional analysis of mutations in TGIF associated with holoprosencephaly.
Kenia B El-Jaick, Shannon E Powers, Laurent Bartholin, Kenneth R Myers, Jin Hahn, Ieda M Orioli, Maia Ouspenskaia, Felicitas Lacbawan, Erich Roessler, David Wotton,[...]. Mol Genet Metab 2007
54
37

The mutational spectrum of the sonic hedgehog gene in holoprosencephaly: SHH mutations cause a significant proportion of autosomal dominant holoprosencephaly.
L Nanni, J E Ming, M Bocian, K Steinhaus, D W Bianchi, C Die-Smulders, A Giannotti, K Imaizumi, K L Jones, M D Campo,[...]. Hum Mol Genet 1999
258
19

The molecular genetics of holoprosencephaly.
Erich Roessler, Maximilian Muenke. Am J Med Genet C Semin Med Genet 2010
155
19

Holoprosencephaly.
Christèle Dubourg, Claude Bendavid, Laurent Pasquier, Catherine Henry, Sylvie Odent, Véronique David. Orphanet J Rare Dis 2007
221
19

Maternal Tgif is required for vascularization of the embryonic placenta.
Laurent Bartholin, Tiffany A Melhuish, Shannon E Powers, Sophie Goddard-Léon, Isabelle Treilleux, Ann E Sutherland, David Wotton. Dev Biol 2008
37
48

New findings for phenotype-genotype correlations in a large European series of holoprosencephaly cases.
Sandra Mercier, Christèle Dubourg, Nicolas Garcelon, Boris Campillo-Gimenez, Isabelle Gicquel, Marion Belleguic, Leslie Ratié, Laurent Pasquier, Philippe Loget, Claude Bendavid,[...]. J Med Genet 2011
76
22

Multiple modes of repression by the Smad transcriptional corepressor TGIF.
D Wotton, R S Lo, L A Swaby, J Massagué. J Biol Chem 1999
154
16


Truncating loss-of-function mutations of DISP1 contribute to holoprosencephaly-like microform features in humans.
Erich Roessler, Yong Ma, Maia V Ouspenskaia, Felicitas Lacbawan, Claude Bendavid, Christèle Dubourg, Philip A Beachy, Maximilian Muenke. Hum Genet 2009
50
30

A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects.
June M de la Cruz, Richard N Bamford, Rebecca D Burdine, Erich Roessler, A James Barkovich, Dian Donnai, Alexander F Schier, Maximilian Muenke. Hum Genet 2002
80
18



Reduced NODAL signaling strength via mutation of several pathway members including FOXH1 is linked to human heart defects and holoprosencephaly.
Erich Roessler, Maia V Ouspenskaia, Jayaprakash D Karkera, Jorge I Vélez, Amy Kantipong, Felicitas Lacbawan, Peter Bowers, John W Belmont, Jeffrey A Towbin, Elizabeth Goldmuntz,[...]. Am J Hum Genet 2008
101
14

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function.
C Chiang, Y Litingtung, E Lee, K E Young, J L Corden, H Westphal, P A Beachy. Nature 1996
14

Analysis of genotype-phenotype correlations in human holoprosencephaly.
Benjamin D Solomon, Sandra Mercier, Jorge I Vélez, Daniel E Pineda-Alvarez, Adrian Wyllie, Nan Zhou, Christèle Dubourg, Veronique David, Sylvie Odent, Erich Roessler,[...]. Am J Med Genet C Semin Med Genet 2010
107
14

Tgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation.
Shannon E Powers, Kenichiro Taniguchi, Weiwei Yen, Tiffany A Melhuish, Jun Shen, Christopher A Walsh, Ann E Sutherland, David Wotton. Development 2010
45
31


Zic2-associated holoprosencephaly is caused by a transient defect in the organizer region during gastrulation.
Nicholas Warr, Nicola Powles-Glover, Anna Chappell, Joan Robson, Dominic Norris, Ruth M Arkell. Hum Mol Genet 2008
68
19

Mutations in ZIC2 in human holoprosencephaly: description of a novel ZIC2 specific phenotype and comprehensive analysis of 157 individuals.
Benjamin D Solomon, Felicitas Lacbawan, Sandra Mercier, Nancy J Clegg, Mauricio R Delgado, Kenneth Rosenbaum, Christèle Dubourg, Veronique David, Ann Haskins Olney, Lars-Erik Wehner,[...]. J Med Genet 2010
57
22

Mutations in CDON, encoding a hedgehog receptor, result in holoprosencephaly and defective interactions with other hedgehog receptors.
Gyu-Un Bae, Sabina Domené, Erich Roessler, Karen Schachter, Jong-Sun Kang, Maximilian Muenke, Robert S Krauss. Am J Hum Genet 2011
90
14

Amplification and overexpression of TGIF2, a novel homeobox gene of the TALE superclass, in ovarian cancer cell lines.
I Imoto, A Pimkhaokham, T Watanabe, F Saito-Ohara, E Soeda, J Inazawa. Biochem Biophys Res Commun 2000
84
15

Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly.
E Belloni, M Muenke, E Roessler, G Traverso, J Siegel-Bartelt, A Frumkin, H F Mitchell, H Donis-Keller, C Helms, A V Hing,[...]. Nat Genet 1996
487
13

Expression and functional analysis of Tgif during mouse midline development.
Jiu-Zhen Jin, Shi Gu, Patrick McKinney, Jixiang Ding. Dev Dyn 2006
29
41

Genetics of ventral forebrain development and holoprosencephaly.
M Muenke, P A Beachy. Curr Opin Genet Dev 2000
197
12

Clinical spectrum of SIX3-associated mutations in holoprosencephaly: correlation between genotype, phenotype and function.
F Lacbawan, B D Solomon, E Roessler, K El-Jaick, S Domené, J I Vélez, N Zhou, D Hadley, J Z Balog, R Long,[...]. J Med Genet 2009
65
18

Monosomy 18p.
Catherine Turleau. Orphanet J Rare Dis 2008
72
16



Molecular screening of SHH, ZIC2, SIX3, and TGIF genes in patients with features of holoprosencephaly spectrum: Mutation review and genotype-phenotype correlations.
Christèle Dubourg, Leïla Lazaro, Laurent Pasquier, Claude Bendavid, Martine Blayau, Franck Le Duff, Marie-Renée Durou, Sylvie Odent, Véronique David. Hum Mutat 2004
115
11

TGIF2 interacts with histone deacetylase 1 and represses transcription.
T A Melhuish, C M Gallo, D Wotton. J Biol Chem 2001
96
11


The Smad transcriptional corepressor TGIF recruits mSin3.
D Wotton, P S Knoepfler, C D Laherty, R N Eisenman, J Massagué. Cell Growth Differ 2001
101
11

The unfolding clinical spectrum of holoprosencephaly due to mutations in SHH, ZIC2, SIX3 and TGIF genes.
Aimée D C Paulussen, Constance T Schrander-Stumpel, Demis C J Tserpelis, Matteus K M Spee, Alexander P A Stegmann, Grazia M Mancini, Alice S Brooks, Margriet Collée, Anneke Maat-Kievit, Marleen E H Simon,[...]. Eur J Hum Genet 2010
32
34

Molecular screening of the TGIF gene in holoprosencephaly: identification of two novel mutations.
Céline Aguilella, Christèle Dubourg, Jocelyne Attia-Sobol, Jacqueline Vigneron, Martine Blayau, Laurent Pasquier, Leila Lazaro, Sylvie Odent, Véronique David. Hum Genet 2003
38
28

Epidermal growth factor-induced hepatocellular carcinoma: gene expression profiles in precursor lesions, early stage and solitary tumours.
Jürgen Borlak, Tatiana Meier, Roman Halter, Reinhard Spanel, Katharina Spanel-Borowski. Oncogene 2005
91
10

The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradation.
Su Ryeon Seo, François Lallemand, Nathalie Ferrand, Marcia Pessah, Sébastien L'Hoste, Jacques Camonis, Azeddine Atfi. EMBO J 2004
120
10

TGIF governs a feed-forward network that empowers Wnt signaling to drive mammary tumorigenesis.
Ming-Zhu Zhang, Olivier Ferrigno, Zhe Wang, Mutsuko Ohnishi, Céline Prunier, Laurence Levy, Mohammed Razzaque, Williams C Horne, Damian Romero, Guri Tzivion,[...]. Cancer Cell 2015
37
27

Mutations in the C-terminal domain of Sonic Hedgehog cause holoprosencephaly.
E Roessler, E Belloni, K Gaudenz, F Vargas, S W Scherer, L C Tsui, M Muenke. Hum Mol Genet 1997
131
9

The mutational spectrum of holoprosencephaly-associated changes within the SHH gene in humans predicts loss-of-function through either key structural alterations of the ligand or its altered synthesis.
Erich Roessler, Kenia B El-Jaick, Christèle Dubourg, Jorge I Vélez, Benjamin D Solomon, Daniel E Pineda-Alvarez, Felicitas Lacbawan, Nan Zhou, Maia Ouspenskaia, Aimée Paulussen,[...]. Hum Mutat 2009
62
14

The full spectrum of holoprosencephaly-associated mutations within the ZIC2 gene in humans predicts loss-of-function as the predominant disease mechanism.
Erich Roessler, Felicitas Lacbawan, Christèle Dubourg, Aimee Paulussen, Jos Herbergs, Ute Hehr, Claude Bendavid, Nan Zhou, Maia Ouspenskaia, Sherri Bale,[...]. Hum Mutat 2009
49
18

Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription.
Y Yang, C K Hwang, U M D'Souza, S H Lee, E Junn, M M Mouradian. J Biol Chem 2000
67
13


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.