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Times Cited: 147
Times Cited: 147
Times Cited
Times Co-cited
Similarity
Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis.
Laura Kennedy, Elizabeth Evans, Chiung-Mei Chen, Lyndsey Craven, Peter J Detloff, Margaret Ennis, Peggy F Shelbourne. Hum Mol Genet 2003
Laura Kennedy, Elizabeth Evans, Chiung-Mei Chen, Lyndsey Craven, Peter J Detloff, Margaret Ennis, Peggy F Shelbourne. Hum Mol Genet 2003
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Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice.
K Manley, T L Shirley, L Flaherty, A Messer. Nat Genet 1999
K Manley, T L Shirley, L Flaherty, A Messer. Nat Genet 1999
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43
Somatic and gonadal mosaicism of the Huntington disease gene CAG repeat in brain and sperm.
H Telenius, B Kremer, Y P Goldberg, J Theilmann, S E Andrew, J Zeisler, S Adam, C Greenberg, E J Ives, L A Clarke. Nat Genet 1994
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Mismatch repair gene Msh2 modifies the timing of early disease in Hdh(Q111) striatum.
Vanessa C Wheeler, Lori-Anne Lebel, Vladimir Vrbanac, Allison Teed, Hein te Riele, Marcy E MacDonald. Hum Mol Genet 2003
Vanessa C Wheeler, Lori-Anne Lebel, Vladimir Vrbanac, Allison Teed, Hein te Riele, Marcy E MacDonald. Hum Mol Genet 2003
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Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation.
L Mangiarini, K Sathasivam, A Mahal, R Mott, M Seller, G P Bates. Nat Genet 1997
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Triplet repeat mutation length gains correlate with cell-type specific vulnerability in Huntington disease brain.
Peggy F Shelbourne, Christine Keller-McGandy, Wenya Linda Bi, Song-Ro Yoon, Louis Dubeau, Nicola J Veitch, Jean Paul Vonsattel, Nancy S Wexler, Norman Arnheim, Sarah J Augood. Hum Mol Genet 2007
Peggy F Shelbourne, Christine Keller-McGandy, Wenya Linda Bi, Song-Ro Yoon, Louis Dubeau, Nicola J Veitch, Jean Paul Vonsattel, Nancy S Wexler, Norman Arnheim, Sarah J Augood. Hum Mol Genet 2007
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Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse.
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Somatic expansion behaviour of the (CTG)n repeat in myotonic dystrophy knock-in mice is differentially affected by Msh3 and Msh6 mismatch-repair proteins.
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Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset.
Meera Swami, Audrey E Hendricks, Tammy Gillis, Tiffany Massood, Jayalakshmi Mysore, Richard H Myers, Vanessa C Wheeler. Hum Mol Genet 2009
Meera Swami, Audrey E Hendricks, Tammy Gillis, Tiffany Massood, Jayalakshmi Mysore, Richard H Myers, Vanessa C Wheeler. Hum Mol Genet 2009
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OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells.
Irina V Kovtun, Yuan Liu, Magnar Bjoras, Arne Klungland, Samuel H Wilson, Cynthia T McMurray. Nature 2007
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Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instability.
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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
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Pms2 is a genetic enhancer of trinucleotide CAG.CTG repeat somatic mosaicism: implications for the mechanism of triplet repeat expansion.
Mário Gomes-Pereira, M Teresa Fortune, Laura Ingram, John P McAbney, Darren G Monckton. Hum Mol Genet 2004
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DNA instability in postmitotic neurons.
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CTG repeat instability and size variation timing in DNA repair-deficient mice.
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Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes.
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Trinucleotide repeat length instability and age of onset in Huntington's disease.
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Neuropathological classification of Huntington's disease.
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Repeat instability: mechanisms of dynamic mutations.
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Age-dependent and tissue-specific CAG repeat instability occurs in mouse knock-in for a mutant Huntington's disease gene.
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Neurological abnormalities in a knock-in mouse model of Huntington's disease.
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Somatic mosaicism, germline expansions, germline reversions and intergenerational reductions in myotonic dystrophy males: small pool PCR analyses.
D G Monckton, L J Wong, T Ashizawa, C T Caskey. Hum Mol Genet 1995
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A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice.
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Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice.
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Trinucleotide expansion in haploid germ cells by gap repair.
I V Kovtun, C T McMurray. Nat Genet 2001
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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
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Regional differences of somatic CAG repeat instability do not account for selective neuronal vulnerability in a knock-in mouse model of SCA1.
Kei Watase, Koen J T Venken, Yaling Sun, Harry T Orr, Huda Y Zoghbi. Hum Mol Genet 2003
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(CAG)(n)-hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition.
Barbara A L Owen, Zungyoon Yang, Maoyi Lai, Maciej Gajec, John D Badger, Jeffrey J Hayes, Winfried Edelmann, Raju Kucherlapati, Teresa M Wilson, Cynthia T McMurray. Nat Struct Mol Biol 2005
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CAG expansion affects the expression of mutant Huntingtin in the Huntington's disease brain.
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Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset.
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Inherited CAG.CTG allele length is a major modifier of somatic mutation length variability in Huntington disease.
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Repeat instability as the basis for human diseases and as a potential target for therapy.
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A novel approach to investigate tissue-specific trinucleotide repeat instability.
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Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion.
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Mechanisms of trinucleotide repeat instability during human development.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.