A citation-based method for searching scientific literature

N Kunishima, Y Shimada, Y Tsuji, T Sato, M Yamamoto, T Kumasaka, S Nakanishi, H Jingami, K Morikawa. Nature 2000
Times Cited: 932







List of co-cited articles
1134 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Structural insights into the activation of metabotropic glutamate receptors.
Antoine Koehl, Hongli Hu, Dan Feng, Bingfa Sun, Yan Zhang, Michael J Robertson, Matthew Chu, Tong Sun Kobilka, Toon Laeremans, Jan Steyaert,[...]. Nature 2019
132
42

Structures of the extracellular regions of the group II/III metabotropic glutamate receptors.
Takanori Muto, Daisuke Tsuchiya, Kosuke Morikawa, Hisato Jingami. Proc Natl Acad Sci U S A 2007
265
40

Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.
Daisuke Tsuchiya, Naoki Kunishima, Narutoshi Kamiya, Hisato Jingami, Kosuke Morikawa. Proc Natl Acad Sci U S A 2002
279
29

Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator.
Huixian Wu, Chong Wang, Karen J Gregory, Gye Won Han, Hyekyung P Cho, Yan Xia, Colleen M Niswender, Vsevolod Katritch, Jens Meiler, Vadim Cherezov,[...]. Science 2014
361
29

Metabotropic glutamate receptors: physiology, pharmacology, and disease.
Colleen M Niswender, P Jeffrey Conn. Annu Rev Pharmacol Toxicol 2010
27

Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain.
Andrew S Doré, Krzysztof Okrasa, Jayesh C Patel, Maria Serrano-Vega, Kirstie Bennett, Robert M Cooke, James C Errey, Ali Jazayeri, Samir Khan, Ben Tehan,[...]. Nature 2014
289
26

Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer.
Li Xue, Xavier Rovira, Pauline Scholler, Han Zhao, Jianfeng Liu, Jean-Philippe Pin, Philippe Rondard. Nat Chem Biol 2015
120
23

Organization and functions of mGlu and GABAB receptor complexes.
Jean-Philippe Pin, Bernhard Bettler. Nature 2016
126
20

Closed state of both binding domains of homodimeric mGlu receptors is required for full activity.
Julie Kniazeff, Anne-Sophie Bessis, Damien Maurel, Hervé Ansanay, Laurent Prézeau, Jean-Philippe Pin. Nat Struct Mol Biol 2004
215
19

Structural mechanism of ligand activation in human GABA(B) receptor.
Yong Geng, Martin Bush, Lidia Mosyak, Feng Wang, Qing R Fan. Nature 2013
114
19

Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors.
Joshua Levitz, Chris Habrian, Shashank Bharill, Zhu Fu, Reza Vafabakhsh, Ehud Y Isacoff. Neuron 2016
89
21

A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors.
Etienne Doumazane, Pauline Scholler, Jurriaan M Zwier, Eric Trinquet, Philippe Rondard, Jean-Philippe Pin. FASEB J 2011
198
18

Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling.
Driss El Moustaine, Sébastien Granier, Etienne Doumazane, Pauline Scholler, Rita Rahmeh, Patrick Bron, Bernard Mouillac, Jean-Louis Banères, Philippe Rondard, Jean-Philippe Pin. Proc Natl Acad Sci U S A 2012
120
17

Structural mechanism of ligand activation in human calcium-sensing receptor.
Yong Geng, Lidia Mosyak, Igor Kurinov, Hao Zuo, Emmanuel Sturchler, Tat Cheung Cheng, Prakash Subramanyam, Alice P Brown, Sarah C Brennan, Hee-Chang Mun,[...]. Elife 2016
113
16

Illuminating the activation mechanisms and allosteric properties of metabotropic glutamate receptors.
Etienne Doumazane, Pauline Scholler, Ludovic Fabre, Jurriaan M Zwier, Eric Trinquet, Jean-Philippe Pin, Philippe Rondard. Proc Natl Acad Sci U S A 2013
72
22

Conformational dynamics of a class C G-protein-coupled receptor.
Reza Vafabakhsh, Joshua Levitz, Ehud Y Isacoff. Nature 2015
99
16

Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors.
Jean-Philippe Pin, Thierry Galvez, Laurent Prézeau. Pharmacol Ther 2003
449
16

Human receptors for sweet and umami taste.
Xiaodong Li, Lena Staszewski, Hong Xu, Kyle Durick, Mark Zoller, Elliot Adler. Proc Natl Acad Sci U S A 2002
838
15

An amino-acid taste receptor.
Greg Nelson, Jayaram Chandrashekar, Mark A Hoon, Luxin Feng, Grace Zhao, Nicholas J P Ryba, Charles S Zuker. Nature 2002
890
15

Interdomain movements in metabotropic glutamate receptor activation.
Siluo Huang, Jianhua Cao, Ming Jiang, Gilles Labesse, Jianfeng Liu, Jean-Philippe Pin, Philippe Rondard. Proc Natl Acad Sci U S A 2011
59
23

Fragment and Structure-Based Drug Discovery for a Class C GPCR: Discovery of the mGlu5 Negative Allosteric Modulator HTL14242 (3-Chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile).
John A Christopher, Sarah J Aves, Kirstie A Bennett, Andrew S Doré, James C Errey, Ali Jazayeri, Fiona H Marshall, Krzysztof Okrasa, Maria J Serrano-Vega, Benjamin G Tehan,[...]. J Med Chem 2015
104
14

Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS.
Shen Yin, Meredith J Noetzel, Kari A Johnson, Rocio Zamorano, Nidhi Jalan-Sakrikar, Karen J Gregory, P Jeffrey Conn, Colleen M Niswender. J Neurosci 2014
80
17

Metabotropic glutamate receptor 5 is a disulfide-linked dimer.
C Romano, W L Yang, K L O'Malley. J Biol Chem 1996
416
14

Mammalian sweet taste receptors.
G Nelson, M A Hoon, J Chandrashekar, Y Zhang, N J Ryba, C S Zuker. Cell 2001
13

Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu5) X-ray Structures.
John A Christopher, Zoltán Orgován, Miles Congreve, Andrew S Doré, James C Errey, Fiona H Marshall, Jonathan S Mason, Krzysztof Okrasa, Prakash Rucktooa, Maria J Serrano-Vega,[...]. J Med Chem 2019
45
26

Structural basis for perception of diverse chemical substances by T1r taste receptors.
Nipawan Nuemket, Norihisa Yasui, Yuko Kusakabe, Yukiyo Nomura, Nanako Atsumi, Shuji Akiyama, Eriko Nango, Yukinari Kato, Mika K Kaneko, Junichi Takagi,[...]. Nat Commun 2017
47
25

Molecular mechanism for the umami taste synergism.
Feng Zhang, Boris Klebansky, Richard M Fine, Hong Xu, Alexey Pronin, Haitian Liu, Catherine Tachdjian, Xiaodong Li. Proc Natl Acad Sci U S A 2008
187
11

Different functional roles of T1R subunits in the heteromeric taste receptors.
Hong Xu, Lena Staszewski, Huixian Tang, Elliot Adler, Mark Zoller, Xiaodong Li. Proc Natl Acad Sci U S A 2004
308
11

Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells.
David Moreno Delgado, Thor C Møller, Jeanne Ster, Jesús Giraldo, Damien Maurel, Xavier Rovira, Pauline Scholler, Jurriaan M Zwier, Julie Perroy, Thierry Durroux,[...]. Elife 2017
42
26

Chloride ions stabilize the glutamate-induced active state of the metabotropic glutamate receptor 3.
Amélie S Tora, Xavier Rovira, Anne-Marinette Cao, Alexandre Cabayé, Linnéa Olofsson, Fanny Malhaire, Pauline Scholler, Hayeon Baik, Ann Van Eeckhaut, Ilse Smolders,[...]. Neuropharmacology 2018
15
73

Molecular mechanism of the sweet taste enhancers.
Feng Zhang, Boris Klebansky, Richard M Fine, Haitian Liu, Hong Xu, Guy Servant, Mark Zoller, Catherine Tachdjian, Xiaodong Li. Proc Natl Acad Sci U S A 2010
109
11

Structural basis of the activation of a metabotropic GABA receptor.
Hamidreza Shaye, Andrii Ishchenko, Jordy Homing Lam, Gye Won Han, Li Xue, Philippe Rondard, Jean-Philippe Pin, Vsevolod Katritch, Cornelius Gati, Vadim Cherezov. Nature 2020
44
25

Pharmacology and functions of metabotropic glutamate receptors.
P J Conn, J P Pin. Annu Rev Pharmacol Toxicol 1997
10

Sequential inter- and intrasubunit rearrangements during activation of dimeric metabotropic glutamate receptor 1.
Veronika Hlavackova, Ulrike Zabel, Daniela Frankova, Julia Bätz, Carsten Hoffmann, Laurent Prezeau, Jean-Philippe Pin, Jaroslav Blahos, Martin J Lohse. Sci Signal 2012
59
16

Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.
Chen Zhang, Tuo Zhang, Juan Zou, Cassandra Lynn Miller, Rakshya Gorkhali, Jeong-Yeh Yang, Anthony Schilmiller, Shuo Wang, Kenneth Huang, Edward M Brown,[...]. Sci Adv 2016
71
14

Fine tuning of sub-millisecond conformational dynamics controls metabotropic glutamate receptors agonist efficacy.
Linnea Olofsson, Suren Felekyan, Etienne Doumazane, Pauline Scholler, Ludovic Fabre, Jurriaan M Zwier, Philippe Rondard, Claus A M Seidel, Jean-Philippe Pin, Emmanuel Margeat. Nat Commun 2014
63
15

Evidence for a single heptahelical domain being turned on upon activation of a dimeric GPCR.
Veronika Hlavackova, Cyril Goudet, Julie Kniazeff, Alice Zikova, Damien Maurel, Claire Vol, Johana Trojanova, Laurent Prézeau, Jean-Philippe Pin, Jaroslav Blahos. EMBO J 2005
119
10

Dimers and beyond: The functional puzzles of class C GPCRs.
Julie Kniazeff, Laurent Prézeau, Philippe Rondard, Jean-Philippe Pin, Cyril Goudet. Pharmacol Ther 2011
159
10

L-amino acid sensing by the extracellular Ca2+-sensing receptor.
A D Conigrave, S J Quinn, E M Brown. Proc Natl Acad Sci U S A 2000
358
10

Cryo-EM structures of inactive and active GABAB receptor.
Chunyou Mao, Cangsong Shen, Chuntao Li, Dan-Dan Shen, Chanjuan Xu, Shenglan Zhang, Rui Zhou, Qingya Shen, Li-Nan Chen, Zhinong Jiang,[...]. Cell Res 2020
38
26

Two distinct determinants of ligand specificity in T1R1/T1R3 (the umami taste receptor).
Yasuka Toda, Tomoya Nakagita, Takashi Hayakawa, Shinji Okada, Masataka Narukawa, Hiroo Imai, Yoshiro Ishimaru, Takumi Misaka. J Biol Chem 2013
46
19

Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists.
Anne-Sophie Bessis, Philippe Rondard, Florence Gaven, Isabelle Brabet, Nicolas Triballeau, Laurent Prezeau, Francine Acher, Jean-Philippe Pin. Proc Natl Acad Sci U S A 2002
89
10

Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors.
Cyril Goudet, Florence Gaven, Julie Kniazeff, Claire Vol, Jiangfeng Liu, Martin Cohen-Gonsaud, Francine Acher, Laurent Prézeau, Jean Philippe Pin. Proc Natl Acad Sci U S A 2004
157
9

Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer.
Junke Liu, Zongyong Zhang, David Moreno-Delgado, James Ar Dalton, Xavier Rovira, Ana Trapero, Cyril Goudet, Amadeu Llebaria, Jesús Giraldo, Qilin Yuan,[...]. Elife 2017
35
25

Towards a structural understanding of allosteric drugs at the human calcium-sensing receptor.
Katie Leach, Karen J Gregory, Irina Kufareva, Elham Khajehali, Anna E Cook, Ruben Abagyan, Arthur D Conigrave, Patrick M Sexton, Arthur Christopoulos. Cell Res 2016
54
16

The calcium-sensing receptor in physiology and in calcitropic and noncalcitropic diseases.
Fadil M Hannan, Enikö Kallay, Wenhan Chang, Maria Luisa Brandi, Rajesh V Thakker. Nat Rev Endocrinol 2018
101
9

Conformational dynamics between transmembrane domains and allosteric modulation of a metabotropic glutamate receptor.
Vanessa A Gutzeit, Jordana Thibado, Daniel Starer Stor, Zhou Zhou, Scott C Blanchard, Olaf S Andersen, Joshua Levitz. Elife 2019
20
45

Conformational pathway provides unique sensitivity to a synaptic mGluR.
Chris H Habrian, Joshua Levitz, Vojtech Vyklicky, Zhu Fu, Adam Hoagland, Isabelle McCort-Tranchepain, Francine Acher, Ehud Y Isacoff. Nat Commun 2019
20
45

Structures of metabotropic GABAB receptor.
Makaía M Papasergi-Scott, Michael J Robertson, Alpay B Seven, Ouliana Panova, Jesper M Mathiesen, Georgios Skiniotis. Nature 2020
34
26



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.