A citation-based method for searching scientific literature

P Fernandez-Funez, M L Nino-Rosales, B de Gouyon, W C She, J M Luchak, P Martinez, E Turiegano, J Benito, M Capovilla, P J Skinner, A McCall, I Canal, H T Orr, H Y Zoghbi, J Botas. Nature 2000
Times Cited: 483

List of co-cited articles
1359 articles co-cited >1

Times Cited
  Times     Co-cited

Genetic suppression of polyglutamine toxicity in Drosophila.
P Kazemi-Esfarjani, S Benzer. Science 2000

Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1.
H T Orr, M Y Chung, S Banfi, T J Kwiatkowski, A Servadio, A L Beaudet, A E McCall, L A Duvick, L P Ranum, H Y Zoghbi. Nat Genet 1993

RAS-MAPK-MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1.
Jeehye Park, Ismael Al-Ramahi, Qiumin Tan, Nissa Mollema, Javier R Diaz-Garcia, Tatiana Gallego-Flores, Hsiang-Chih Lu, Sarita Lagalwar, Lisa Duvick, Hyojin Kang,[...]. Nature 2013

Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.
J M Warrick, H Y Chan, G L Gray-Board, Y Chai, H L Paulson, N M Bonini. Nat Genet 1999

Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila.
J M Warrick, H L Paulson, G L Gray-Board, Q T Bui, K H Fischbeck, R N Pittman, N M Bonini. Cell 1998

ATAXIN-1 interacts with the repressor Capicua in its native complex to cause SCA1 neuropathology.
Yung C Lam, Aaron B Bowman, Paymaan Jafar-Nejad, Janghoo Lim, Ronald Richman, John D Fryer, Eric D Hyun, Lisa A Duvick, Harry T Orr, Juan Botas,[...]. Cell 2006

Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.
I A Klement, P J Skinner, M D Kaytor, H Yi, S M Hersch, H B Clark, H Y Zoghbi, H T Orr. Cell 1998

A long CAG repeat in the mouse Sca1 locus replicates SCA1 features and reveals the impact of protein solubility on selective neurodegeneration.
Kei Watase, Edwin J Weeber, Bisong Xu, Barbara Antalffy, Lisa Yuva-Paylor, Kouichi Hashimoto, Masanobu Kano, Richard Atkinson, Yaling Sun, Dawna L Armstrong,[...]. Neuron 2002

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila.
J S Steffan, L Bodai, J Pallos, M Poelman, A McCampbell, B L Apostol, A Kazantsev, E Schmidt, Y Z Zhu, M Greenwald,[...]. Nature 2001

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.
C J Cummings, M A Mancini, B Antalffy, D B DeFranco, H T Orr, H Y Zoghbi. Nat Genet 1998

Trinucleotide repeat disorders.
Harry T Orr, Huda Y Zoghbi. Annu Rev Neurosci 2007

Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.
G R Jackson, I Salecker, X Dong, X Yao, N Arnheim, P W Faber, M E MacDonald, S L Zipursky. Neuron 1998

Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice.
Effat S Emamian, Michael D Kaytor, Lisa A Duvick, Tao Zu, Susan K Tousey, Huda Y Zoghbi, H Brent Clark, Harry T Orr. Neuron 2003

SCA1 transgenic mice: a model for neurodegeneration caused by an expanded CAG trinucleotide repeat.
E N Burright, H B Clark, A Servadio, T Matilla, R M Feddersen, W S Yunis, L A Duvick, H Y Zoghbi, H T Orr. Cell 1995

Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1.
Janghoo Lim, Juan Crespo-Barreto, Paymaan Jafar-Nejad, Aaron B Bowman, Ronald Richman, David E Hill, Harry T Orr, Huda Y Zoghbi. Nature 2008

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997

The AXH domain of Ataxin-1 mediates neurodegeneration through its interaction with Gfi-1/Senseless proteins.
Hiroshi Tsuda, Hamed Jafar-Nejad, Akash J Patel, Yaling Sun, Hung-Kai Chen, Matthew F Rose, Koen J T Venken, Juan Botas, Harry T Orr, Hugo J Bellen,[...]. Cell 2005

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS.
Udai Bhan Pandey, Zhiping Nie, Yakup Batlevi, Brett A McCray, Gillian P Ritson, Natalia B Nedelsky, Stephanie L Schwartz, Nicholas A DiProspero, Melanie A Knight, Oren Schuldiner,[...]. Nature 2007

Pumilio1 haploinsufficiency leads to SCA1-like neurodegeneration by increasing wild-type Ataxin1 levels.
Vincenzo A Gennarino, Ravi K Singh, Joshua J White, Antonia De Maio, Kihoon Han, Ji-Yoen Kim, Paymaan Jafar-Nejad, Alberto di Ronza, Hyojin Kang, Layal S Sayegh,[...]. Cell 2015

Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1.
Hung-Kai Chen, Pedro Fernandez-Funez, Summer F Acevedo, Yung C Lam, Michael D Kaytor, Michael H Fernandez, Alastair Aitken, Efthimios M C Skoulakis, Harry T Orr, Juan Botas,[...]. Cell 2003

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS.
Andrew C Elden, Hyung-Jun Kim, Michael P Hart, Alice S Chen-Plotkin, Brian S Johnson, Xiaodong Fang, Maria Armakola, Felix Geser, Robert Greene, Min Min Lu,[...]. Nature 2010

A Drosophila model of Parkinson's disease.
M B Feany, W W Bender. Nature 2000

Suppression of neurodegeneration and increased neurotransmission caused by expanded full-length huntingtin accumulating in the cytoplasm.
Eliana Romero, Guang-Ho Cha, Patrik Verstreken, Cindy V Ly, Robert E Hughes, Hugo J Bellen, Juan Botas. Neuron 2008

Glutamine repeats and neurodegeneration.
H Y Zoghbi, H T Orr. Annu Rev Neurosci 2000

Huntingtin interacting proteins are genetic modifiers of neurodegeneration.
Linda S Kaltenbach, Eliana Romero, Robert R Becklin, Rakesh Chettier, Russell Bell, Amit Phansalkar, Andrew Strand, Cameron Torcassi, Justin Savage, Anthony Hurlburt,[...]. PLoS Genet 2007

SCA17, a novel autosomal dominant cerebellar ataxia caused by an expanded polyglutamine in TATA-binding protein.
K Nakamura, S Y Jeong, T Uchihara, M Anno, K Nagashima, T Nagashima, S Ikeda, S Tsuji, I Kanazawa. Hum Mol Genet 2001

CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1.
Y Kawaguchi, T Okamoto, M Taniwaki, M Aizawa, M Inoue, S Katayama, H Kawakami, S Nakamura, M Nishimura, I Akiguchi. Nat Genet 1994

Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice.
C J Cummings, Y Sun, P Opal, B Antalffy, R Mestril, H T Orr, W H Dillmann, H Y Zoghbi. Hum Mol Genet 2001

Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the alpha 1A-voltage-dependent calcium channel.
O Zhuchenko, J Bailey, P Bonnen, T Ashizawa, D W Stockton, C Amos, W B Dobyns, S H Subramony, H Y Zoghbi, C C Lee. Nat Genet 1997

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease.
Pavan K Auluck, H Y Edwin Chan, John Q Trojanowski, Virginia M Y Lee, Nancy M Bonini. Science 2002

Native functions of the androgen receptor are essential to pathogenesis in a Drosophila model of spinobulbar muscular atrophy.
Natalia B Nedelsky, Maria Pennuto, Rebecca B Smith, Isabella Palazzolo, Jennifer Moore, Zhiping Nie, Geoffrey Neale, J Paul Taylor. Neuron 2010

Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone.
D L Stenoien, C J Cummings, H P Adams, M G Mancini, K Patel, G N DeMartino, M Marcelli, N L Weigel, M A Mancini. Hum Mol Genet 1999

RORalpha-mediated Purkinje cell development determines disease severity in adult SCA1 mice.
Heliane G Serra, Lisa Duvick, Tao Zu, Kerri Carlson, Sam Stevens, Nathan Jorgensen, Alana Lysholm, Eric Burright, Huda Y Zoghbi, H Brent Clark,[...]. Cell 2006

Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion.
G David, N Abbas, G Stevanin, A Dürr, G Yvert, G Cancel, C Weber, G Imbert, F Saudou, E Antoniou,[...]. Nat Genet 1997

Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.
H L Paulson, M K Perez, Y Trottier, J Q Trojanowski, S H Subramony, S S Das, P Vig, J L Mandel, K H Fischbeck, R N Pittman. Neuron 1997

A conditional pan-neuronal Drosophila model of spinocerebellar ataxia 7 with a reversible adult phenotype suitable for identifying modifier genes.
Morwena Latouche, Christelle Lasbleiz, Elodie Martin, Véronique Monnier, Thomas Debeir, Annick Mouatt-Prigent, Marie-Paule Muriel, Lydie Morel, Merle Ruberg, Alexis Brice,[...]. J Neurosci 2007

Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2.
S M Pulst, A Nechiporuk, T Nechiporuk, S Gispert, X N Chen, I Lopes-Cendes, S Pearlman, S Starkman, G Orozco-Diaz, A Lunkes,[...]. Nat Genet 1996

A neurological disease caused by an expanded CAG trinucleotide repeat in the TATA-binding protein gene: a new polyglutamine disease?
R Koide, S Kobayashi, T Shimohata, T Ikeuchi, M Maruyama, M Saito, M Yamada, H Takahashi, S Tsuji. Hum Mol Genet 1999

A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43.
Nicholas A Lanson, Astha Maltare, Hanna King, Rebecca Smith, Ji Han Kim, J Paul Taylor, Thomas E Lloyd, Udai Bhan Pandey. Hum Mol Genet 2011

Probing mechanisms that underlie human neurodegenerative diseases in Drosophila.
M Jaiswal, H Sandoval, K Zhang, V Bayat, H J Bellen. Annu Rev Genet 2012

Ataxin-3 suppresses polyglutamine neurodegeneration in Drosophila by a ubiquitin-associated mechanism.
John M Warrick, Lance M Morabito, Julide Bilen, Beth Gordesky-Gold, Lynn Z Faust, Henry L Paulson, Nancy M Bonini. Mol Cell 2005

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004

A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster.
L T Reiter, L Potocki, S Chien, M Gribskov, E Bier. Genome Res 2001

Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.