W Liedtke, Y Choe, M A Martí-Renom, A M Bell, C S Denis, A Sali, A J Hudspeth, J M Friedman, S Heller. Cell 2000
Times Cited: 959
Times Cited: 959
Times Cited
Times Co-cited
Similarity
OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity.
R Strotmann, C Harteneck, K Nunnenmacher, G Schultz, T D Plant. Nat Cell Biol 2000
R Strotmann, C Harteneck, K Nunnenmacher, G Schultz, T D Plant. Nat Cell Biol 2000
52
The capsaicin receptor: a heat-activated ion channel in the pain pathway.
M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius. Nature 1997
M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius. Nature 1997
27
Abnormal osmotic regulation in trpv4-/- mice.
Wolfgang Liedtke, Jeffrey M Friedman. Proc Natl Acad Sci U S A 2003
Wolfgang Liedtke, Jeffrey M Friedman. Proc Natl Acad Sci U S A 2003
26
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels.
Hiroyuki Watanabe, Joris Vriens, Jean Prenen, Guy Droogmans, Thomas Voets, Bernd Nilius. Nature 2003
Hiroyuki Watanabe, Joris Vriens, Jean Prenen, Guy Droogmans, Thomas Voets, Bernd Nilius. Nature 2003
25
Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4.
J Vriens, H Watanabe, A Janssens, G Droogmans, T Voets, B Nilius. Proc Natl Acad Sci U S A 2004
J Vriens, H Watanabe, A Janssens, G Droogmans, T Voets, B Nilius. Proc Natl Acad Sci U S A 2004
23
Heat-evoked activation of the ion channel, TRPV4.
Ali Deniz Güler, Hyosang Lee, Tohko Iida, Isao Shimizu, Makoto Tominaga, Michael Caterina. J Neurosci 2002
Ali Deniz Güler, Hyosang Lee, Tohko Iida, Isao Shimizu, Makoto Tominaga, Michael Caterina. J Neurosci 2002
23
Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells.
Hiroyuki Watanabe, Joris Vriens, Suk H Suh, Christopher D Benham, Guy Droogmans, Bernd Nilius. J Biol Chem 2002
Hiroyuki Watanabe, Joris Vriens, Suk H Suh, Christopher D Benham, Guy Droogmans, Bernd Nilius. J Biol Chem 2002
22
Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives.
Hiroyuki Watanabe, John B Davis, Darren Smart, Jeff C Jerman, Graham D Smith, Phil Hayes, Joris Vriens, William Cairns, Ullrich Wissenbach, Jean Prenen,[...]. J Biol Chem 2002
Hiroyuki Watanabe, John B Davis, Darren Smart, Jeff C Jerman, Graham D Smith, Phil Hayes, Joris Vriens, William Cairns, Ullrich Wissenbach, Jean Prenen,[...]. J Biol Chem 2002
19
Impaired pressure sensation in mice lacking TRPV4.
Makoto Suzuki, Atsuko Mizuno, Kunihiko Kodaira, Masashi Imai. J Biol Chem 2003
Makoto Suzuki, Atsuko Mizuno, Kunihiko Kodaira, Masashi Imai. J Biol Chem 2003
18
TRPV4: Molecular Conductor of a Diverse Orchestra.
John P M White, Mario Cibelli, Laszlo Urban, Bernd Nilius, J Graham McGeown, Istvan Nagy. Physiol Rev 2016
John P M White, Mario Cibelli, Laszlo Urban, Bernd Nilius, J Graham McGeown, Istvan Nagy. Physiol Rev 2016
18
Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis.
Wouter Everaerts, Xiaoguang Zhen, Debapriya Ghosh, Joris Vriens, Thomas Gevaert, James P Gilbert, Neil J Hayward, Colleen R McNamara, Fenqin Xue, Magdalene M Moran,[...]. Proc Natl Acad Sci U S A 2010
Wouter Everaerts, Xiaoguang Zhen, Debapriya Ghosh, Joris Vriens, Thomas Gevaert, James P Gilbert, Neil J Hayward, Colleen R McNamara, Fenqin Xue, Magdalene M Moran,[...]. Proc Natl Acad Sci U S A 2010
17
Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels.
Bertrand Coste, Jayanti Mathur, Manuela Schmidt, Taryn J Earley, Sanjeev Ranade, Matt J Petrus, Adrienne E Dubin, Ardem Patapoutian. Science 2010
Bertrand Coste, Jayanti Mathur, Manuela Schmidt, Taryn J Earley, Sanjeev Ranade, Matt J Petrus, Adrienne E Dubin, Ardem Patapoutian. Science 2010
17
The TRPV4 cation channel mediates stretch-evoked Ca2+ influx and ATP release in primary urothelial cell cultures.
Tsutomu Mochizuki, Takaaki Sokabe, Isao Araki, Kayoko Fujishita, Koji Shibasaki, Kunitoshi Uchida, Keiji Naruse, Schuichi Koizumi, Masayuki Takeda, Makoto Tominaga. J Biol Chem 2009
Tsutomu Mochizuki, Takaaki Sokabe, Isao Araki, Kayoko Fujishita, Koji Shibasaki, Kunitoshi Uchida, Keiji Naruse, Schuichi Koizumi, Masayuki Takeda, Makoto Tominaga. J Biol Chem 2009
14
N-((1S)-1-{[4-((2S)-2-{[(2,4-dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a novel and potent transient receptor potential vanilloid 4 channel agonist induces urinary bladder contraction and hyperactivity: Part I.
Kevin S Thorneloe, Anthony C Sulpizio, Zuojun Lin, David J Figueroa, Angela K Clouse, Gerald P McCafferty, Tim P Chendrimada, Erin S R Lashinger, Earl Gordon, Louise Evans,[...]. J Pharmacol Exp Ther 2008
Kevin S Thorneloe, Anthony C Sulpizio, Zuojun Lin, David J Figueroa, Angela K Clouse, Gerald P McCafferty, Tim P Chendrimada, Erin S R Lashinger, Earl Gordon, Louise Evans,[...]. J Pharmacol Exp Ther 2008
14
Hypotonicity induces TRPV4-mediated nociception in rat.
Nicole Alessandri-Haber, Jenny J Yeh, Aileen E Boyd, Carlos A Parada, Xiaojie Chen, David B Reichling, Jon D Levine. Neuron 2003
Nicole Alessandri-Haber, Jenny J Yeh, Aileen E Boyd, Carlos A Parada, Xiaojie Chen, David B Reichling, Jon D Levine. Neuron 2003
13
Wild-type and brachyolmia-causing mutant TRPV4 channels respond directly to stretch force.
Stephen Loukin, Xinliang Zhou, Zhenwei Su, Yoshiro Saimi, Ching Kung. J Biol Chem 2010
Stephen Loukin, Xinliang Zhou, Zhenwei Su, Yoshiro Saimi, Ching Kung. J Biol Chem 2010
13
Trp12, a novel Trp related protein from kidney.
U Wissenbach, M Bödding, M Freichel, V Flockerzi. FEBS Lett 2000
U Wissenbach, M Bödding, M Freichel, V Flockerzi. FEBS Lett 2000
12
TRPV4 calcium entry channel: a paradigm for gating diversity.
Bernd Nilius, Joris Vriens, Jean Prenen, Guy Droogmans, Thomas Voets. Am J Physiol Cell Physiol 2004
Bernd Nilius, Joris Vriens, Jean Prenen, Guy Droogmans, Thomas Voets. Am J Physiol Cell Physiol 2004
12
An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure.
Kevin S Thorneloe, Mui Cheung, Weike Bao, Hasan Alsaid, Stephen Lenhard, Ming-Yuan Jian, Melissa Costell, Kristeen Maniscalco-Hauk, John A Krawiec, Alan Olzinski,[...]. Sci Transl Med 2012
Kevin S Thorneloe, Mui Cheung, Weike Bao, Hasan Alsaid, Stephen Lenhard, Ming-Yuan Jian, Melissa Costell, Kristeen Maniscalco-Hauk, John A Krawiec, Alan Olzinski,[...]. Sci Transl Med 2012
12
Modulation of the Ca2 permeable cation channel TRPV4 by cytochrome P450 epoxygenases in vascular endothelium.
J Vriens, G Owsianik, B Fisslthaler, M Suzuki, A Janssens, T Voets, C Morisseau, B D Hammock, I Fleming, R Busse,[...]. Circ Res 2005
J Vriens, G Owsianik, B Fisslthaler, M Suzuki, A Janssens, T Voets, C Morisseau, B D Hammock, I Fleming, R Busse,[...]. Circ Res 2005
12
Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes.
Martha Rocio Servin-Vences, Mirko Moroni, Gary R Lewin, Kate Poole. Elife 2017
Martha Rocio Servin-Vences, Mirko Moroni, Gary R Lewin, Kate Poole. Elife 2017
12
The vanilloid transient receptor potential channel TRPV4: from structure to disease.
Wouter Everaerts, Bernd Nilius, Grzegorz Owsianik. Prog Biophys Mol Biol 2010
Wouter Everaerts, Bernd Nilius, Grzegorz Owsianik. Prog Biophys Mol Biol 2010
11
A capsaicin-receptor homologue with a high threshold for noxious heat.
M J Caterina, T A Rosen, M Tominaga, A J Brake, D Julius. Nature 1999
M J Caterina, T A Rosen, M Tominaga, A J Brake, D Julius. Nature 1999
11
11
Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans.
Wolfgang Liedtke, David M Tobin, Cornelia I Bargmann, Jeffrey M Friedman. Proc Natl Acad Sci U S A 2003
Wolfgang Liedtke, David M Tobin, Cornelia I Bargmann, Jeffrey M Friedman. Proc Natl Acad Sci U S A 2003
11
Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding.
Thomas Gevaert, Joris Vriens, Andrei Segal, Wouter Everaerts, Tania Roskams, Karel Talavera, Grzegorz Owsianik, Wolfgang Liedtke, Dirk Daelemans, Ilse Dewachter,[...]. J Clin Invest 2007
Thomas Gevaert, Joris Vriens, Andrei Segal, Wouter Everaerts, Tania Roskams, Karel Talavera, Grzegorz Owsianik, Wolfgang Liedtke, Dirk Daelemans, Ilse Dewachter,[...]. J Clin Invest 2007
11
TRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Müller Glia.
Andrew O Jo, Daniel A Ryskamp, Tam T T Phuong, Alan S Verkman, Oleg Yarishkin, Nanna MacAulay, David Križaj. J Neurosci 2015
Andrew O Jo, Daniel A Ryskamp, Tam T T Phuong, Alan S Verkman, Oleg Yarishkin, Nanna MacAulay, David Križaj. J Neurosci 2015
11
Piezo1, a mechanically activated ion channel, is required for vascular development in mice.
Sanjeev S Ranade, Zhaozhu Qiu, Seung-Hyun Woo, Sung Sik Hur, Swetha E Murthy, Stuart M Cahalan, Jie Xu, Jayanti Mathur, Michael Bandell, Bertrand Coste,[...]. Proc Natl Acad Sci U S A 2014
Sanjeev S Ranade, Zhaozhu Qiu, Seung-Hyun Woo, Sung Sik Hur, Swetha E Murthy, Stuart M Cahalan, Jie Xu, Jayanti Mathur, Michael Bandell, Bertrand Coste,[...]. Proc Natl Acad Sci U S A 2014
11
TRPV2 is a component of osmotically sensitive cation channels in murine aortic myocytes.
Katsuhiko Muraki, Yuko Iwata, Yuki Katanosaka, Tomohiro Ito, Susumu Ohya, Munekazu Shigekawa, Yuji Imaizumi. Circ Res 2003
Katsuhiko Muraki, Yuko Iwata, Yuki Katanosaka, Tomohiro Ito, Susumu Ohya, Munekazu Shigekawa, Yuji Imaizumi. Circ Res 2003
11
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures.
Gina M Story, Andrea M Peier, Alison J Reeve, Samer R Eid, Johannes Mosbacher, Todd R Hricik, Taryn J Earley, Anne C Hergarden, David A Andersson, Sun Wook Hwang,[...]. Cell 2003
Gina M Story, Andrea M Peier, Alison J Reeve, Samer R Eid, Johannes Mosbacher, Todd R Hricik, Taryn J Earley, Anne C Hergarden, David A Andersson, Sun Wook Hwang,[...]. Cell 2003
11
TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice.
Shaik O Rahaman, Lisa M Grove, Sailaja Paruchuri, Brian D Southern, Susamma Abraham, Kathryn A Niese, Rachel G Scheraga, Sudakshina Ghosh, Charles K Thodeti, David X Zhang,[...]. J Clin Invest 2014
Shaik O Rahaman, Lisa M Grove, Sailaja Paruchuri, Brian D Southern, Susamma Abraham, Kathryn A Niese, Rachel G Scheraga, Sudakshina Ghosh, Charles K Thodeti, David X Zhang,[...]. J Clin Invest 2014
10
Warm temperatures activate TRPV4 in mouse 308 keratinocytes.
Man-Kyo Chung, Hyosang Lee, Michael J Caterina. J Biol Chem 2003
Man-Kyo Chung, Hyosang Lee, Michael J Caterina. J Biol Chem 2003
10
TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling.
Charles K Thodeti, Benjamin Matthews, Arvind Ravi, Akiko Mammoto, Kaustabh Ghosh, Abigail L Bracha, Donald E Ingber. Circ Res 2009
Charles K Thodeti, Benjamin Matthews, Arvind Ravi, Akiko Mammoto, Kaustabh Ghosh, Abigail L Bracha, Donald E Ingber. Circ Res 2009
10
An N-terminal variant of Trpv1 channel is required for osmosensory transduction.
Reza Sharif Naeini, Marie-France Witty, Philippe Séguéla, Charles W Bourque. Nat Neurosci 2006
Reza Sharif Naeini, Marie-France Witty, Philippe Séguéla, Charles W Bourque. Nat Neurosci 2006
10
Swelling and eicosanoid metabolites differentially gate TRPV4 channels in retinal neurons and glia.
Daniel A Ryskamp, Andrew O Jo, Amber M Frye, Felix Vazquez-Chona, Nanna MacAulay, Wallace B Thoreson, David Križaj. J Neurosci 2014
Daniel A Ryskamp, Andrew O Jo, Amber M Frye, Felix Vazquez-Chona, Nanna MacAulay, Wallace B Thoreson, David Križaj. J Neurosci 2014
15
Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms.
Zengqin Deng, Navid Paknejad, Grigory Maksaev, Monica Sala-Rabanal, Colin G Nichols, Richard K Hite, Peng Yuan. Nat Struct Mol Biol 2018
Zengqin Deng, Navid Paknejad, Grigory Maksaev, Monica Sala-Rabanal, Colin G Nichols, Richard K Hite, Peng Yuan. Nat Struct Mol Biol 2018
10
Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface beta1 integrins.
Benjamin D Matthews, Charles K Thodeti, Jessica D Tytell, Akiko Mammoto, Darryl R Overby, Donald E Ingber. Integr Biol (Camb) 2010
Benjamin D Matthews, Charles K Thodeti, Jessica D Tytell, Akiko Mammoto, Darryl R Overby, Donald E Ingber. Integr Biol (Camb) 2010
10
Activation of the TRPV4 ion channel is enhanced by phosphorylation.
Hueng-Chuen Fan, Xuming Zhang, Peter A McNaughton. J Biol Chem 2009
Hueng-Chuen Fan, Xuming Zhang, Peter A McNaughton. J Biol Chem 2009
10
Piezo1 integration of vascular architecture with physiological force.
Jing Li, Bing Hou, Sarka Tumova, Katsuhiko Muraki, Alexander Bruns, Melanie J Ludlow, Alicia Sedo, Adam J Hyman, Lynn McKeown, Richard S Young,[...]. Nature 2014
Jing Li, Bing Hou, Sarka Tumova, Katsuhiko Muraki, Alexander Bruns, Melanie J Ludlow, Alicia Sedo, Adam J Hyman, Lynn McKeown, Richard S Young,[...]. Nature 2014
10
Retinal Detachment-Induced Müller Glial Cell Swelling Activates TRPV4 Ion Channels and Triggers Photoreceptor Death at Body Temperature.
Hidetaka Matsumoto, Shouta Sugio, François Seghers, David Krizaj, Hideo Akiyama, Yasuki Ishizaki, Philippe Gailly, Koji Shibasaki. J Neurosci 2018
Hidetaka Matsumoto, Shouta Sugio, François Seghers, David Krizaj, Hideo Akiyama, Yasuki Ishizaki, Philippe Gailly, Koji Shibasaki. J Neurosci 2018
28
Impaired osmotic sensation in mice lacking TRPV4.
Atsuko Mizuno, Naoko Matsumoto, Masashi Imai, Makoto Suzuki. Am J Physiol Cell Physiol 2003
Atsuko Mizuno, Naoko Matsumoto, Masashi Imai, Makoto Suzuki. Am J Physiol Cell Physiol 2003
9
TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress.
Suelhem A Mendoza, Juan Fang, David D Gutterman, David A Wilcox, Aaron H Bubolz, Rongshan Li, Makoto Suzuki, David X Zhang. Am J Physiol Heart Circ Physiol 2010
Suelhem A Mendoza, Juan Fang, David D Gutterman, David A Wilcox, Aaron H Bubolz, Rongshan Li, Makoto Suzuki, David X Zhang. Am J Physiol Heart Circ Physiol 2010
9
Temperature-modulated diversity of TRPV4 channel gating: activation by physical stresses and phorbol ester derivatives through protein kinase C-dependent and -independent pathways.
Xiaochong Gao, Ling Wu, Roger G O'Neil. J Biol Chem 2003
Xiaochong Gao, Ling Wu, Roger G O'Neil. J Biol Chem 2003
9
TRPV4 regulates calcium homeostasis, cytoskeletal remodeling, conventional outflow and intraocular pressure in the mammalian eye.
Daniel A Ryskamp, Amber M Frye, Tam T T Phuong, Oleg Yarishkin, Andrew O Jo, Yong Xu, Monika Lakk, Anthony Iuso, Sarah N Redmon, Balamurali Ambati,[...]. Sci Rep 2016
Daniel A Ryskamp, Amber M Frye, Tam T T Phuong, Oleg Yarishkin, Andrew O Jo, Yong Xu, Monika Lakk, Anthony Iuso, Sarah N Redmon, Balamurali Ambati,[...]. Sci Rep 2016
16
Ca2+-dependent potentiation of the nonselective cation channel TRPV4 is mediated by a C-terminal calmodulin binding site.
Rainer Strotmann, Gunter Schultz, Tim D Plant. J Biol Chem 2003
Rainer Strotmann, Gunter Schultz, Tim D Plant. J Biol Chem 2003
9
Phosphatidylinositol-4,5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli.
Anna Garcia-Elias, Sanela Mrkonjic, Carlos Pardo-Pastor, Hitoshi Inada, Ute A Hellmich, Fanny Rubio-Moscardó, Cristina Plata, Rachelle Gaudet, Rubén Vicente, Miguel A Valverde. Proc Natl Acad Sci U S A 2013
Anna Garcia-Elias, Sanela Mrkonjic, Carlos Pardo-Pastor, Hitoshi Inada, Ute A Hellmich, Fanny Rubio-Moscardó, Cristina Plata, Rachelle Gaudet, Rubén Vicente, Miguel A Valverde. Proc Natl Acad Sci U S A 2013
10
Molecular determinants of permeation through the cation channel TRPV4.
Thomas Voets, Jean Prenen, Joris Vriens, Hiroyuki Watanabe, Annelies Janssens, Ulrich Wissenbach, Matthias Bödding, Guy Droogmans, Bernd Nilius. J Biol Chem 2002
Thomas Voets, Jean Prenen, Joris Vriens, Hiroyuki Watanabe, Annelies Janssens, Ulrich Wissenbach, Matthias Bödding, Guy Droogmans, Bernd Nilius. J Biol Chem 2002
9
UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling.
Carlene Moore, Ferda Cevikbas, H Amalia Pasolli, Yong Chen, Wei Kong, Cordula Kempkes, Puja Parekh, Suk Hee Lee, Nelly-Ange Kontchou, Iwei Yeh,[...]. Proc Natl Acad Sci U S A 2013
Carlene Moore, Ferda Cevikbas, H Amalia Pasolli, Yong Chen, Wei Kong, Cordula Kempkes, Puja Parekh, Suk Hee Lee, Nelly-Ange Kontchou, Iwei Yeh,[...]. Proc Natl Acad Sci U S A 2013
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.