A citation-based method for searching scientific literature

R D Ramirez, C P Morales, B S Herbert, J M Rohde, C Passons, J W Shay, W E Wright. Genes Dev 2001
Times Cited: 309







List of co-cited articles
1013 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


A biomarker that identifies senescent human cells in culture and in aging skin in vivo.
G P Dimri, X Lee, G Basile, M Acosta, G Scott, C Roskelley, E E Medrano, M Linskens, I Rubelj, O Pereira-Smith. Proc Natl Acad Sci U S A 1995
38

Extension of life-span by introduction of telomerase into normal human cells.
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
34

The serial cultivation of human diploid cell strains.
L HAYFLICK, P S MOORHEAD. Exp Cell Res 1961
26


Cellular senescence: when bad things happen to good cells.
Judith Campisi, Fabrizio d'Adda di Fagagna. Nat Rev Mol Cell Biol 2007
21

A DNA damage checkpoint response in telomere-initiated senescence.
Fabrizio d'Adda di Fagagna, Philip M Reaper, Lorena Clay-Farrace, Heike Fiegler, Philippa Carr, Thomas Von Zglinicki, Gabriele Saretzki, Nigel P Carter, Stephen P Jackson. Nature 2003
20

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.
T Kiyono, S A Foster, J I Koop, J K McDougall, D A Galloway, A J Klingelhutz. Nature 1998
838
19

BRAFE600-associated senescence-like cell cycle arrest of human naevi.
Chrysiis Michaloglou, Liesbeth C W Vredeveld, Maria S Soengas, Christophe Denoyelle, Thomas Kuilman, Chantal M A M van der Horst, Donné M Majoor, Jerry W Shay, Wolter J Mooi, Daniel S Peeper. Nature 2005
18

Telomeres shorten during ageing of human fibroblasts.
C B Harley, A B Futcher, C W Greider. Nature 1990
18

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence.
Masashi Narita, Sabrina Nũnez, Edith Heard, Masako Narita, Athena W Lin, Stephen A Hearn, David L Spector, Gregory J Hannon, Scott W Lowe. Cell 2003
17


Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis.
Zhenbang Chen, Lloyd C Trotman, David Shaffer, Hui-Kuan Lin, Zohar A Dotan, Masaru Niki, Jason A Koutcher, Howard I Scher, Thomas Ludwig, William Gerald,[...]. Nature 2005
15

Tumour biology: senescence in premalignant tumours.
Manuel Collado, Jesús Gil, Alejo Efeyan, Carmen Guerra, Alberto J Schuhmacher, Marta Barradas, Alberto Benguría, Angel Zaballos, Juana M Flores, Mariano Barbacid,[...]. Nature 2005
943
15

Reversal of human cellular senescence: roles of the p53 and p16 pathways.
Christian M Beauséjour, Ana Krtolica, Francesco Galimi, Masashi Narita, Scott W Lowe, Paul Yaswen, Judith Campisi. EMBO J 2003
752
15

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a).
Utz Herbig, Wendy A Jobling, Benjamin P C Chen, David J Chen, John M Sedivy. Mol Cell 2004
760
14

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.
Jean-Philippe Coppé, Christopher K Patil, Francis Rodier, Yu Sun, Denise P Muñoz, Joshua Goldstein, Peter S Nelson, Pierre-Yves Desprez, Judith Campisi. PLoS Biol 2008
14

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas.
Wen Xue, Lars Zender, Cornelius Miething, Ross A Dickins, Eva Hernando, Valery Krizhanovsky, Carlos Cordon-Cardo, Scott W Lowe. Nature 2007
13

Oncogene-induced senescence as an initial barrier in lymphoma development.
Melanie Braig, Soyoung Lee, Christoph Loddenkemper, Cornelia Rudolph, Antoine H F M Peters, Brigitte Schlegelberger, Harald Stein, Bernd Dörken, Thomas Jenuwein, Clemens A Schmitt. Nature 2005
783
13

Accumulation of senescent cells in mitotic tissue of aging primates.
Jessie C Jeyapalan, Mark Ferreira, John M Sedivy, Utz Herbig. Mech Ageing Dev 2007
356
12

Historical claims and current interpretations of replicative aging.
Woodring E Wright, Jerry W Shay. Nat Biotechnol 2002
233
12

Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging.
A Krtolica, S Parrinello, S Lockett, P Y Desprez, J Campisi. Proc Natl Acad Sci U S A 2001
894
12

Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
12

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.
Francis Rodier, Jean-Philippe Coppé, Christopher K Patil, Wieteke A M Hoeijmakers, Denise P Muñoz, Saba R Raza, Adam Freund, Eric Campeau, Albert R Davalos, Judith Campisi. Nat Cell Biol 2009
12


Cellular senescence in aging primates.
Utz Herbig, Mark Ferreira, Laura Condel, Dee Carey, John M Sedivy. Science 2006
630
11

DNA damage is able to induce senescence in tumor cells in vitro and in vivo.
Robert H te Poele, Andrei L Okorokov, Lesley Jardine, Jeffrey Cummings, Simon P Joel. Cancer Res 2002
409
11

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication.
Raffaella Di Micco, Marzia Fumagalli, Angelo Cicalese, Sara Piccinin, Patrizia Gasparini, Chiara Luise, Catherine Schurra, Massimiliano Garre', Paolo Giovanni Nuciforo, Aaron Bensimon,[...]. Nature 2006
11

Senescence of activated stellate cells limits liver fibrosis.
Valery Krizhanovsky, Monica Yon, Ross A Dickins, Stephen Hearn, Janelle Simon, Cornelius Miething, Herman Yee, Lars Zender, Scott W Lowe. Cell 2008
981
11

The essence of senescence.
Thomas Kuilman, Chrysiis Michaloglou, Wolter J Mooi, Daniel S Peeper. Genes Dev 2010
11

Human cell senescence as a DNA damage response.
T von Zglinicki, G Saretzki, J Ladhoff, F d'Adda di Fagagna, S P Jackson. Mech Ageing Dev 2005
260
10

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts.
D A Alcorta, Y Xiong, D Phelps, G Hannon, D Beach, J C Barrett. Proc Natl Acad Sci U S A 1996
594
10

Ink4a/Arf expression is a biomarker of aging.
Janakiraman Krishnamurthy, Chad Torrice, Matthew R Ramsey, Grigoriy I Kovalev, Khalid Al-Regaiey, Lishan Su, Norman E Sharpless. J Clin Invest 2004
850
10

Senescence-messaging secretome: SMS-ing cellular stress.
Thomas Kuilman, Daniel S Peeper. Nat Rev Cancer 2009
510
10

The senescence-associated secretory phenotype: the dark side of tumor suppression.
Jean-Philippe Coppé, Pierre-Yves Desprez, Ana Krtolica, Judith Campisi. Annu Rev Pathol 2010
10

Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins.
Ruben D Ramirez, Shelley Sheridan, Luc Girard, Mitsuo Sato, Young Kim, Jon Pollack, Michael Peyton, Ying Zou, Jonathan M Kurie, J Michael Dimaio,[...]. Cancer Res 2004
434
9


A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation.
Masashi Narita, Masako Narita, Valery Krizhanovsky, Sabrina Nuñez, Agustin Chicas, Stephen A Hearn, Michael P Myers, Scott W Lowe. Cell 2006
390
9

A negative feedback signaling network underlies oncogene-induced senescence.
Stéphanie Courtois-Cox, Sybil M Genther Williams, Elizabeth E Reczek, Bryan W Johnson, Lauren T McGillicuddy, Cory M Johannessen, Pablo E Hollstein, Mia MacCollin, Karen Cichowski. Cancer Cell 2006
360
9

Restoration of p53 function leads to tumour regression in vivo.
Andrea Ventura, David G Kirsch, Margaret E McLaughlin, David A Tuveson, Jan Grimm, Laura Lintault, Jamie Newman, Elizabeth E Reczek, Ralph Weissleder, Tyler Jacks. Nature 2007
9

Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation.
Simona Parrinello, Jean-Philippe Coppe, Ana Krtolica, Judith Campisi. J Cell Sci 2005
354
9

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.
Thomas Kuilman, Chrysiis Michaloglou, Liesbeth C W Vredeveld, Sirith Douma, Remco van Doorn, Christophe J Desmet, Lucien A Aarden, Wolter J Mooi, Daniel S Peeper. Cell 2008
9

Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.
Narendra Wajapeyee, Ryan W Serra, Xiaochun Zhu, Meera Mahalingam, Michael R Green. Cell 2008
584
9

DNA damage foci at dysfunctional telomeres.
Hiroyuki Takai, Agata Smogorzewska, Titia de Lange. Curr Biol 2003
888
9

Oxidative DNA damage and senescence of human diploid fibroblast cells.
Q Chen, A Fischer, J D Reagan, L J Yan, B N Ames. Proc Natl Acad Sci U S A 1995
423
9

The signals and pathways activating cellular senescence.
Ittai Ben-Porath, Robert A Weinberg. Int J Biochem Cell Biol 2005
639
9

The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence.
Frédérick A Mallette, Marie-France Gaumont-Leclerc, Gerardo Ferbeyre. Genes Dev 2007
290
9


Senescence-associated beta-galactosidase is lysosomal beta-galactosidase.
Bo Yun Lee, Jung A Han, Jun Sub Im, Amelia Morrone, Kimberly Johung, Edward C Goodwin, Wim J Kleijer, Daniel DiMaio, Eun Seong Hwang. Aging Cell 2006
506
9

A role for both RB and p53 in the regulation of human cellular senescence.
J W Shay, O M Pereira-Smith, W E Wright. Exp Cell Res 1991
449
9



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.