S Merscher, B Funke, J A Epstein, J Heyer, A Puech, M M Lu, R J Xavier, M B Demay, R G Russell, S Factor, K Tokooya, B S Jore, M Lopez, R K Pandita, M Lia, D Carrion, H Xu, H Schorle, J B Kobler, P Scambler, A Wynshaw-Boris, A I Skoultchi, B E Morrow, R Kucherlapati. Cell 2001
Times Cited: 665
Times Cited: 665
Times Cited
Times Co-cited
Similarity
Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice.
E A Lindsay, F Vitelli, H Su, M Morishima, T Huynh, T Pramparo, V Jurecic, G Ogunrinu, H F Sutherland, P J Scambler,[...]. Nature 2001
E A Lindsay, F Vitelli, H Su, M Morishima, T Huynh, T Pramparo, V Jurecic, G Ogunrinu, H F Sutherland, P J Scambler,[...]. Nature 2001
55
DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1.
L A Jerome, V E Papaioannou. Nat Genet 2001
L A Jerome, V E Papaioannou. Nat Genet 2001
49
22q11.2 deletion syndrome.
Donna M McDonald-McGinn, Kathleen E Sullivan, Bruno Marino, Nicole Philip, Ann Swillen, Jacob A S Vorstman, Elaine H Zackai, Beverly S Emanuel, Joris R Vermeesch, Bernice E Morrow,[...]. Nat Rev Dis Primers 2015
Donna M McDonald-McGinn, Kathleen E Sullivan, Bruno Marino, Nicole Philip, Ann Swillen, Jacob A S Vorstman, Elaine H Zackai, Beverly S Emanuel, Joris R Vermeesch, Bernice E Morrow,[...]. Nat Rev Dis Primers 2015
34
Role of TBX1 in human del22q11.2 syndrome.
Hisato Yagi, Yoshiyuki Furutani, Hiromichi Hamada, Takashi Sasaki, Shuichi Asakawa, Shinsei Minoshima, Fukiko Ichida, Kunitaka Joo, Misa Kimura, Shin-ichiro Imamura,[...]. Lancet 2003
Hisato Yagi, Yoshiyuki Furutani, Hiromichi Hamada, Takashi Sasaki, Shuichi Asakawa, Shinsei Minoshima, Fukiko Ichida, Kunitaka Joo, Misa Kimura, Shin-ichiro Imamura,[...]. Lancet 2003
28
Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract.
Huansheng Xu, Masae Morishima, John N Wylie, Robert J Schwartz, Benoit G Bruneau, Elizabeth A Lindsay, Antonio Baldini. Development 2004
Huansheng Xu, Masae Morishima, John N Wylie, Robert J Schwartz, Benoit G Bruneau, Elizabeth A Lindsay, Antonio Baldini. Development 2004
18
Modeling a model: Mouse genetics, 22q11.2 Deletion Syndrome, and disorders of cortical circuit development.
Daniel W Meechan, Thomas M Maynard, Eric S Tucker, Alejandra Fernandez, Beverly A Karpinski, Lawrence A Rothblat, Anthony-S LaMantia. Prog Neurobiol 2015
Daniel W Meechan, Thomas M Maynard, Eric S Tucker, Alejandra Fernandez, Beverly A Karpinski, Lawrence A Rothblat, Anthony-S LaMantia. Prog Neurobiol 2015
29
Mesodermal expression of Tbx1 is necessary and sufficient for pharyngeal arch and cardiac outflow tract development.
Zhen Zhang, Tuong Huynh, Antonio Baldini. Development 2006
Zhen Zhang, Tuong Huynh, Antonio Baldini. Development 2006
15
Congenital heart disease in mice deficient for the DiGeorge syndrome region.
E A Lindsay, A Botta, V Jurecic, S Carattini-Rivera, Y C Cheah, H M Rosenblatt, A Bradley, A Baldini. Nature 1999
E A Lindsay, A Botta, V Jurecic, S Carattini-Rivera, Y C Cheah, H M Rosenblatt, A Bradley, A Baldini. Nature 1999
15
Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model.
Kimberly L Stark, Bin Xu, Anindya Bagchi, Wen-Sung Lai, Hui Liu, Ruby Hsu, Xiang Wan, Paul Pavlidis, Alea A Mills, Maria Karayiorgou,[...]. Nat Genet 2008
Kimberly L Stark, Bin Xu, Anindya Bagchi, Wen-Sung Lai, Hui Liu, Ruby Hsu, Xiang Wan, Paul Pavlidis, Alea A Mills, Maria Karayiorgou,[...]. Nat Genet 2008
14
Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathways.
Francesca Vitelli, Masae Morishima, Ilaria Taddei, Elizabeth A Lindsay, Antonio Baldini. Hum Mol Genet 2002
Francesca Vitelli, Masae Morishima, Ilaria Taddei, Elizabeth A Lindsay, Antonio Baldini. Hum Mol Genet 2002
13
The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm.
R G Kelly, N A Brown, M E Buckingham. Dev Cell 2001
R G Kelly, N A Brown, M E Buckingham. Dev Cell 2001
13
Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndrome.
Richard Paylor, Beate Glaser, Annalisa Mupo, Paris Ataliotis, Corinne Spencer, Angela Sobotka, Chelsey Sparks, Chul-Hee Choi, John Oghalai, Sarah Curran,[...]. Proc Natl Acad Sci U S A 2006
Richard Paylor, Beate Glaser, Annalisa Mupo, Paris Ataliotis, Corinne Spencer, Angela Sobotka, Chelsey Sparks, Chul-Hee Choi, John Oghalai, Sarah Curran,[...]. Proc Natl Acad Sci U S A 2006
12
Tbx1 expression in pharyngeal epithelia is necessary for pharyngeal arch artery development.
Zhen Zhang, Fabiana Cerrato, Huansheng Xu, Francesca Vitelli, Masae Morishima, Joshua Vincentz, Yasuhide Furuta, Lijiang Ma, James F Martin, Antonio Baldini,[...]. Development 2005
Zhen Zhang, Fabiana Cerrato, Huansheng Xu, Francesca Vitelli, Masae Morishima, Joshua Vincentz, Yasuhide Furuta, Lijiang Ma, James F Martin, Antonio Baldini,[...]. Development 2005
12
Dose-dependent interaction of Tbx1 and Crkl and locally aberrant RA signaling in a model of del22q11 syndrome.
Deborah L Guris, Gregg Duester, Virginia E Papaioannou, Akira Imamoto. Dev Cell 2006
Deborah L Guris, Gregg Duester, Virginia E Papaioannou, Akira Imamoto. Dev Cell 2006
12
Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge (22q11) deletion syndrome.
Beverly A Karpinski, Thomas M Maynard, Matthew S Fralish, Samer Nuwayhid, Irene E Zohn, Sally A Moody, Anthony-S LaMantia. Dis Model Mech 2014
Beverly A Karpinski, Thomas M Maynard, Matthew S Fralish, Samer Nuwayhid, Irene E Zohn, Sally A Moody, Anthony-S LaMantia. Dis Model Mech 2014
33
22q11 deletion syndrome: a role for TBX1 in pharyngeal and cardiovascular development.
Peter J Scambler. Pediatr Cardiol 2010
Peter J Scambler. Pediatr Cardiol 2010
12
In vivo response to high-resolution variation of Tbx1 mRNA dosage.
Zhen Zhang, Antonio Baldini. Hum Mol Genet 2008
Zhen Zhang, Antonio Baldini. Hum Mol Genet 2008
13
Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart.
Chen-Leng Cai, Xingqun Liang, Yunqing Shi, Po-Hsien Chu, Samuel L Pfaff, Ju Chen, Sylvia Evans. Dev Cell 2003
Chen-Leng Cai, Xingqun Liang, Yunqing Shi, Po-Hsien Chu, Samuel L Pfaff, Ju Chen, Sylvia Evans. Dev Cell 2003
11
Human TBX1 missense mutations cause gain of function resulting in the same phenotype as 22q11.2 deletions.
Christiane Zweier, Heinrich Sticht, Inci Aydin-Yaylagül, Christine E Campbell, Anita Rauch. Am J Hum Genet 2007
Christiane Zweier, Heinrich Sticht, Inci Aydin-Yaylagül, Christine E Campbell, Anita Rauch. Am J Hum Genet 2007
11
Decreased levels of embryonic retinoic acid synthesis accelerate recovery from arterial growth delay in a mouse model of DiGeorge syndrome.
Lucile Ryckebüsch, Nicolas Bertrand, Karim Mesbah, Fanny Bajolle, Karen Niederreither, Robert G Kelly, Stéphane Zaffran. Circ Res 2010
Lucile Ryckebüsch, Nicolas Bertrand, Karim Mesbah, Fanny Bajolle, Karen Niederreither, Robert G Kelly, Stéphane Zaffran. Circ Res 2010
19
Tbx1 controls cardiac neural crest cell migration during arch artery development by regulating Gbx2 expression in the pharyngeal ectoderm.
Amélie Calmont, Sarah Ivins, Kelly Lammerts Van Bueren, Irinna Papangeli, Vanessa Kyriakopoulou, William D Andrews, James F Martin, Anne M Moon, Elizabeth A Illingworth, M Albert Basson,[...]. Development 2009
Amélie Calmont, Sarah Ivins, Kelly Lammerts Van Bueren, Irinna Papangeli, Vanessa Kyriakopoulou, William D Andrews, James F Martin, Anne M Moon, Elizabeth A Illingworth, M Albert Basson,[...]. Development 2009
11
Tbx1 regulates proliferation and differentiation of multipotent heart progenitors.
Li Chen, Filomena Gabriella Fulcoli, Susan Tang, Antonio Baldini. Circ Res 2009
Li Chen, Filomena Gabriella Fulcoli, Susan Tang, Antonio Baldini. Circ Res 2009
10
A population-based study of the 22q11.2 deletion: phenotype, incidence, and contribution to major birth defects in the population.
Lorenzo D Botto, Kristin May, Paul M Fernhoff, Adolfo Correa, Karlene Coleman, Sonja A Rasmussen, Robert K Merritt, Leslie A O'Leary, Lee-Yang Wong, E Marsha Elixson,[...]. Pediatrics 2003
Lorenzo D Botto, Kristin May, Paul M Fernhoff, Adolfo Correa, Karlene Coleman, Sonja A Rasmussen, Robert K Merritt, Leslie A O'Leary, Lee-Yang Wong, E Marsha Elixson,[...]. Pediatrics 2003
10
Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome: results from the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome.
Maude Schneider, Martin Debbané, Anne S Bassett, Eva W C Chow, Wai Lun Alan Fung, Marianne van den Bree, Michael Owen, Kieran C Murphy, Maria Niarchou, Wendy R Kates,[...]. Am J Psychiatry 2014
Maude Schneider, Martin Debbané, Anne S Bassett, Eva W C Chow, Wai Lun Alan Fung, Marianne van den Bree, Michael Owen, Kieran C Murphy, Maria Niarchou, Wendy R Kates,[...]. Am J Psychiatry 2014
10
Spectrum of clinical features associated with interstitial chromosome 22q11 deletions: a European collaborative study.
A K Ryan, J A Goodship, D I Wilson, N Philip, A Levy, H Seidel, S Schuffenhauer, H Oechsler, B Belohradsky, M Prieur,[...]. J Med Genet 1997
A K Ryan, J A Goodship, D I Wilson, N Philip, A Levy, H Seidel, S Schuffenhauer, H Oechsler, B Belohradsky, M Prieur,[...]. J Med Genet 1997
10
Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors.
Tonghuan Hu, Hiroyuki Yamagishi, Jun Maeda, John McAnally, Chihiro Yamagishi, Deepak Srivastava. Development 2004
Tonghuan Hu, Hiroyuki Yamagishi, Jun Maeda, John McAnally, Chihiro Yamagishi, Deepak Srivastava. Development 2004
10
The del22q11.2 candidate gene Tbx1 regulates branchiomeric myogenesis.
Robert G Kelly, Loydie A Jerome-Majewska, Virginia E Papaioannou. Hum Mol Genet 2004
Robert G Kelly, Loydie A Jerome-Majewska, Virginia E Papaioannou. Hum Mol Genet 2004
10
Hard to swallow: Developmental biological insights into pediatric dysphagia.
Anthony-Samuel LaMantia, Sally A Moody, Thomas M Maynard, Beverly A Karpinski, Irene E Zohn, David Mendelowitz, Norman H Lee, Anastas Popratiloff. Dev Biol 2016
Anthony-Samuel LaMantia, Sally A Moody, Thomas M Maynard, Beverly A Karpinski, Irene E Zohn, David Mendelowitz, Norman H Lee, Anastas Popratiloff. Dev Biol 2016
34
22q11 Gene dosage establishes an adaptive range for sonic hedgehog and retinoic acid signaling during early development.
Thomas M Maynard, Deepak Gopalakrishna, Daniel W Meechan, Elizabeth M Paronett, Jason M Newbern, Anthony-Samuel LaMantia. Hum Mol Genet 2013
Thomas M Maynard, Deepak Gopalakrishna, Daniel W Meechan, Elizabeth M Paronett, Jason M Newbern, Anthony-Samuel LaMantia. Hum Mol Genet 2013
29
Mice lacking the homologue of the human 22q11.2 gene CRKL phenocopy neurocristopathies of DiGeorge syndrome.
D L Guris, J Fantes, D Tara, B J Druker, A Imamoto. Nat Genet 2001
D L Guris, J Fantes, D Tara, B J Druker, A Imamoto. Nat Genet 2001
9
Dysphagia in children with a 22q11.2 deletion: unusual pattern found on modified barium swallow.
P S Eicher, D M McDonald-Mcginn, C A Fox, D A Driscoll, B S Emanuel, E H Zackai. J Pediatr 2000
P S Eicher, D M McDonald-Mcginn, C A Fox, D A Driscoll, B S Emanuel, E H Zackai. J Pediatr 2000
12
Chromosome 22-specific low copy repeats and the 22q11.2 deletion syndrome: genomic organization and deletion endpoint analysis.
T H Shaikh, H Kurahashi, S C Saitta, A M O'Hare, P Hu, B A Roe, D A Driscoll, D M McDonald-McGinn, E H Zackai, M L Budarf,[...]. Hum Mol Genet 2000
T H Shaikh, H Kurahashi, S C Saitta, A M O'Hare, P Hu, B A Roe, D A Driscoll, D M McDonald-McGinn, E H Zackai, M L Budarf,[...]. Hum Mol Genet 2000
9
A new heart for a new head in vertebrate cardiopharyngeal evolution.
Rui Diogo, Robert G Kelly, Lionel Christiaen, Michael Levine, Janine M Ziermann, Julia L Molnar, Drew M Noden, Eldad Tzahor. Nature 2015
Rui Diogo, Robert G Kelly, Lionel Christiaen, Michael Levine, Janine M Ziermann, Julia L Molnar, Drew M Noden, Eldad Tzahor. Nature 2015
9
Inactivation of Tbx1 in the pharyngeal endoderm results in 22q11DS malformations.
Jelena S Arnold, Uwe Werling, Evan M Braunstein, Jun Liao, Sonja Nowotschin, Winfried Edelmann, Jean M Hebert, Bernice E Morrow. Development 2006
Jelena S Arnold, Uwe Werling, Evan M Braunstein, Jun Liao, Sonja Nowotschin, Winfried Edelmann, Jean M Hebert, Bernice E Morrow. Development 2006
9
Tbx1, a DiGeorge syndrome candidate gene, is regulated by sonic hedgehog during pharyngeal arch development.
V Garg, C Yamagishi, T Hu, I S Kathiriya, H Yamagishi, D Srivastava. Dev Biol 2001
V Garg, C Yamagishi, T Hu, I S Kathiriya, H Yamagishi, D Srivastava. Dev Biol 2001
9
Molecular definition of 22q11 deletions in 151 velo-cardio-facial syndrome patients.
C Carlson, H Sirotkin, R Pandita, R Goldberg, J McKie, R Wadey, S R Patanjali, S M Weissman, K Anyane-Yeboa, D Warburton,[...]. Am J Hum Genet 1997
C Carlson, H Sirotkin, R Pandita, R Goldberg, J McKie, R Wadey, S R Patanjali, S M Weissman, K Anyane-Yeboa, D Warburton,[...]. Am J Hum Genet 1997
9
Altered neurobiological function of brainstem hypoglossal neurons in DiGeorge/22q11.2 Deletion Syndrome.
Xin Wang, Corey Bryan, Anthony-Samuel LaMantia, David Mendelowitz. Neuroscience 2017
Xin Wang, Corey Bryan, Anthony-Samuel LaMantia, David Mendelowitz. Neuroscience 2017
60
Impaired hippocampal-prefrontal synchrony in a genetic mouse model of schizophrenia.
Torfi Sigurdsson, Kimberly L Stark, Maria Karayiorgou, Joseph A Gogos, Joshua A Gordon. Nature 2010
Torfi Sigurdsson, Kimberly L Stark, Maria Karayiorgou, Joseph A Gogos, Joshua A Gordon. Nature 2010
9
The regional pattern of retinoic acid synthesis by RALDH2 is essential for the development of posterior pharyngeal arches and the enteric nervous system.
Karen Niederreither, Julien Vermot, Isabelle Le Roux, Brigitte Schuhbaur, Pierre Chambon, Pascal Dollé. Development 2003
Karen Niederreither, Julien Vermot, Isabelle Le Roux, Brigitte Schuhbaur, Pierre Chambon, Pascal Dollé. Development 2003
9
Molecular genetics of 22q11.2 deletion syndrome.
Bernice E Morrow, Donna M McDonald-McGinn, Beverly S Emanuel, Joris R Vermeesch, Peter J Scambler. Am J Med Genet A 2018
Bernice E Morrow, Donna M McDonald-McGinn, Beverly S Emanuel, Joris R Vermeesch, Peter J Scambler. Am J Med Genet A 2018
24
Retinoic acid down-regulates Tbx1 expression in vivo and in vitro.
Catherine Roberts, Sarah M Ivins, Chela T James, Peter J Scambler. Dev Dyn 2005
Catherine Roberts, Sarah M Ivins, Chela T James, Peter J Scambler. Dev Dyn 2005
10
22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia.
Maria Karayiorgou, Tony J Simon, Joseph A Gogos. Nat Rev Neurosci 2010
Maria Karayiorgou, Tony J Simon, Joseph A Gogos. Nat Rev Neurosci 2010
8
A genetic link between Tbx1 and fibroblast growth factor signaling.
Francesca Vitelli, Ilaria Taddei, Masae Morishima, Erik N Meyers, Elizabeth A Lindsay, Antonio Baldini. Development 2002
Francesca Vitelli, Ilaria Taddei, Masae Morishima, Erik N Meyers, Elizabeth A Lindsay, Antonio Baldini. Development 2002
8
Low-copy repeats mediate the common 3-Mb deletion in patients with velo-cardio-facial syndrome.
L Edelmann, R K Pandita, B E Morrow. Am J Hum Genet 1999
L Edelmann, R K Pandita, B E Morrow. Am J Hum Genet 1999
8
Mouse and human CRKL is dosage sensitive for cardiac outflow tract formation.
Silvia E Racedo, Donna M McDonald-McGinn, Jonathan H Chung, Elizabeth Goldmuntz, Elaine Zackai, Beverly S Emanuel, Bin Zhou, Birgit Funke, Bernice E Morrow. Am J Hum Genet 2015
Silvia E Racedo, Donna M McDonald-McGinn, Jonathan H Chung, Elizabeth Goldmuntz, Elaine Zackai, Beverly S Emanuel, Bin Zhou, Birgit Funke, Bernice E Morrow. Am J Hum Genet 2015
19
Phenotype of the 22q11.2 deletion in individuals identified through an affected relative: cast a wide FISHing net!
D M McDonald-McGinn, M K Tonnesen, A Laufer-Cahana, B Finucane, D A Driscoll, B S Emanuel, E H Zackai. Genet Med 2001
D M McDonald-McGinn, M K Tonnesen, A Laufer-Cahana, B Finucane, D A Driscoll, B S Emanuel, E H Zackai. Genet Med 2001
8
Chromosome 22q11.2 deletion syndrome (DiGeorge syndrome/velocardiofacial syndrome).
Donna M McDonald-McGinn, Kathleen E Sullivan. Medicine (Baltimore) 2011
Donna M McDonald-McGinn, Kathleen E Sullivan. Medicine (Baltimore) 2011
8
Full spectrum of malformations in velo-cardio-facial syndrome/DiGeorge syndrome mouse models by altering Tbx1 dosage.
Jun Liao, Lazaros Kochilas, Sonja Nowotschin, Jelena S Arnold, Vimla S Aggarwal, Jonathan A Epstein, M Christian Brown, Joe Adams, Bernice E Morrow. Hum Mol Genet 2004
Jun Liao, Lazaros Kochilas, Sonja Nowotschin, Jelena S Arnold, Vimla S Aggarwal, Jonathan A Epstein, M Christian Brown, Joe Adams, Bernice E Morrow. Hum Mol Genet 2004
8
Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family.
Q Y Li, R A Newbury-Ecob, J A Terrett, D I Wilson, A R Curtis, C H Yi, T Gebuhr, P J Bullen, S C Robson, T Strachan,[...]. Nat Genet 1997
Q Y Li, R A Newbury-Ecob, J A Terrett, D I Wilson, A R Curtis, C H Yi, T Gebuhr, P J Bullen, S C Robson, T Strachan,[...]. Nat Genet 1997
8
The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart field.
Michael P Verzi, David J McCulley, Sarah De Val, Evdokia Dodou, Brian L Black. Dev Biol 2005
Michael P Verzi, David J McCulley, Sarah De Val, Evdokia Dodou, Brian L Black. Dev Biol 2005
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.