I V Kovtun, C T McMurray. Nat Genet 2001
Times Cited: 210
Times Cited: 210
Times Cited
Times Co-cited
Similarity
Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice.
K Manley, T L Shirley, L Flaherty, A Messer. Nat Genet 1999
K Manley, T L Shirley, L Flaherty, A Messer. Nat Genet 1999
67
OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells.
Irina V Kovtun, Yuan Liu, Magnar Bjoras, Arne Klungland, Samuel H Wilson, Cynthia T McMurray. Nature 2007
Irina V Kovtun, Yuan Liu, Magnar Bjoras, Arne Klungland, Samuel H Wilson, Cynthia T McMurray. Nature 2007
57
Somatic expansion behaviour of the (CTG)n repeat in myotonic dystrophy knock-in mice is differentially affected by Msh3 and Msh6 mismatch-repair proteins.
Walther J A A van den Broek, Marcel R Nelen, Derick G Wansink, Marga M Coerwinkel, Hein te Riele, Patricia J T A Groenen, Bé Wieringa. Hum Mol Genet 2002
Walther J A A van den Broek, Marcel R Nelen, Derick G Wansink, Marga M Coerwinkel, Hein te Riele, Patricia J T A Groenen, Bé Wieringa. Hum Mol Genet 2002
46
Mismatch repair gene Msh2 modifies the timing of early disease in Hdh(Q111) striatum.
Vanessa C Wheeler, Lori-Anne Lebel, Vladimir Vrbanac, Allison Teed, Hein te Riele, Marcy E MacDonald. Hum Mol Genet 2003
Vanessa C Wheeler, Lori-Anne Lebel, Vladimir Vrbanac, Allison Teed, Hein te Riele, Marcy E MacDonald. Hum Mol Genet 2003
43
CTG repeat instability and size variation timing in DNA repair-deficient mice.
Cédric Savouret, Edith Brisson, Jeroen Essers, Roland Kanaar, Albert Pastink, Hein te Riele, Claudine Junien, Geneviève Gourdon. EMBO J 2003
Cédric Savouret, Edith Brisson, Jeroen Essers, Roland Kanaar, Albert Pastink, Hein te Riele, Claudine Junien, Geneviève Gourdon. EMBO J 2003
42
(CAG)(n)-hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition.
Barbara A L Owen, Zungyoon Yang, Maoyi Lai, Maciej Gajec, John D Badger, Jeffrey J Hayes, Winfried Edelmann, Raju Kucherlapati, Teresa M Wilson, Cynthia T McMurray. Nat Struct Mol Biol 2005
Barbara A L Owen, Zungyoon Yang, Maoyi Lai, Maciej Gajec, John D Badger, Jeffrey J Hayes, Winfried Edelmann, Raju Kucherlapati, Teresa M Wilson, Cynthia T McMurray. Nat Struct Mol Biol 2005
39
Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes.
Ella Dragileva, Audrey Hendricks, Allison Teed, Tammy Gillis, Edith T Lopez, Errol C Friedberg, Raju Kucherlapati, Winfried Edelmann, Kathryn L Lunetta, Marcy E MacDonald,[...]. Neurobiol Dis 2009
Ella Dragileva, Audrey Hendricks, Allison Teed, Tammy Gillis, Edith T Lopez, Errol C Friedberg, Raju Kucherlapati, Winfried Edelmann, Kathryn L Lunetta, Marcy E MacDonald,[...]. Neurobiol Dis 2009
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Repeat instability as the basis for human diseases and as a potential target for therapy.
Arturo López Castel, John D Cleary, Christopher E Pearson. Nat Rev Mol Cell Biol 2010
Arturo López Castel, John D Cleary, Christopher E Pearson. Nat Rev Mol Cell Biol 2010
36
Mechanisms of trinucleotide repeat instability during human development.
Cynthia T McMurray. Nat Rev Genet 2010
Cynthia T McMurray. Nat Rev Genet 2010
36
Pms2 is a genetic enhancer of trinucleotide CAG.CTG repeat somatic mosaicism: implications for the mechanism of triplet repeat expansion.
Mário Gomes-Pereira, M Teresa Fortune, Laura Ingram, John P McAbney, Darren G Monckton. Hum Mol Genet 2004
Mário Gomes-Pereira, M Teresa Fortune, Laura Ingram, John P McAbney, Darren G Monckton. Hum Mol Genet 2004
34
Msh3 is a limiting factor in the formation of intergenerational CTG expansions in DM1 transgenic mice.
Laurent Foiry, Li Dong, Cédric Savouret, Laurence Hubert, Hein te Riele, Claudine Junien, Geneviève Gourdon. Hum Genet 2006
Laurent Foiry, Li Dong, Cédric Savouret, Laurence Hubert, Hein te Riele, Claudine Junien, Geneviève Gourdon. Hum Genet 2006
34
Transcription-induced CAG repeat contraction in human cells is mediated in part by transcription-coupled nucleotide excision repair.
Yunfu Lin, John H Wilson. Mol Cell Biol 2007
Yunfu Lin, John H Wilson. Mol Cell Biol 2007
32
Trinucleotide repeats that expand in human disease form hairpin structures in vitro.
A M Gacy, G Goellner, N Juranić, S Macura, C T McMurray. Cell 1995
A M Gacy, G Goellner, N Juranić, S Macura, C T McMurray. Cell 1995
30
Transcription promotes contraction of CAG repeat tracts in human cells.
Yunfu Lin, Vincent Dion, John H Wilson. Nat Struct Mol Biol 2006
Yunfu Lin, Vincent Dion, John H Wilson. Nat Struct Mol Biol 2006
30
Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis.
Laura Kennedy, Elizabeth Evans, Chiung-Mei Chen, Lyndsey Craven, Peter J Detloff, Margaret Ennis, Peggy F Shelbourne. Hum Mol Genet 2003
Laura Kennedy, Elizabeth Evans, Chiung-Mei Chen, Lyndsey Craven, Peter J Detloff, Margaret Ennis, Peggy F Shelbourne. Hum Mol Genet 2003
29
Repeat instability: mechanisms of dynamic mutations.
Christopher E Pearson, Kerrie Nichol Edamura, John D Cleary. Nat Rev Genet 2005
Christopher E Pearson, Kerrie Nichol Edamura, John D Cleary. Nat Rev Genet 2005
27
MSH2-dependent germinal CTG repeat expansions are produced continuously in spermatogonia from DM1 transgenic mice.
Cédric Savouret, Corinne Garcia-Cordier, Jérôme Megret, Hein te Riele, Claudine Junien, Geneviève Gourdon. Mol Cell Biol 2004
Cédric Savouret, Corinne Garcia-Cordier, Jérôme Megret, Hein te Riele, Claudine Junien, Geneviève Gourdon. Mol Cell Biol 2004
33
DNA instability in postmitotic neurons.
Roman Gonitel, Hilary Moffitt, Kirupa Sathasivam, Ben Woodman, Peter J Detloff, Richard L M Faull, Gillian P Bates. Proc Natl Acad Sci U S A 2008
Roman Gonitel, Hilary Moffitt, Kirupa Sathasivam, Ben Woodman, Peter J Detloff, Richard L M Faull, Gillian P Bates. Proc Natl Acad Sci U S A 2008
25
Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches.
Ricardo Mouro Pinto, Ella Dragileva, Andrew Kirby, Alejandro Lloret, Edith Lopez, Jason St Claire, Gagan B Panigrahi, Caixia Hou, Kim Holloway, Tammy Gillis,[...]. PLoS Genet 2013
Ricardo Mouro Pinto, Ella Dragileva, Andrew Kirby, Alejandro Lloret, Edith Lopez, Jason St Claire, Gagan B Panigrahi, Caixia Hou, Kim Holloway, Tammy Gillis,[...]. PLoS Genet 2013
25
Xpa deficiency reduces CAG trinucleotide repeat instability in neuronal tissues in a mouse model of SCA1.
Leroy Hubert, Yunfu Lin, Vincent Dion, John H Wilson. Hum Mol Genet 2011
Leroy Hubert, Yunfu Lin, Vincent Dion, John H Wilson. Hum Mol Genet 2011
40
Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice.
Agathi-Vassiliki Goula, Brian R Berquist, David M Wilson, Vanessa C Wheeler, Yvon Trottier, Karine Merienne. PLoS Genet 2009
Agathi-Vassiliki Goula, Brian R Berquist, David M Wilson, Vanessa C Wheeler, Yvon Trottier, Karine Merienne. PLoS Genet 2009
22
Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset.
Meera Swami, Audrey E Hendricks, Tammy Gillis, Tiffany Massood, Jayalakshmi Mysore, Richard H Myers, Vanessa C Wheeler. Hum Mol Genet 2009
Meera Swami, Audrey E Hendricks, Tammy Gillis, Tiffany Massood, Jayalakshmi Mysore, Richard H Myers, Vanessa C Wheeler. Hum Mol Genet 2009
21
Triplet repeat mutation length gains correlate with cell-type specific vulnerability in Huntington disease brain.
Peggy F Shelbourne, Christine Keller-McGandy, Wenya Linda Bi, Song-Ro Yoon, Louis Dubeau, Nicola J Veitch, Jean Paul Vonsattel, Nancy S Wexler, Norman Arnheim, Sarah J Augood. Hum Mol Genet 2007
Peggy F Shelbourne, Christine Keller-McGandy, Wenya Linda Bi, Song-Ro Yoon, Louis Dubeau, Nicola J Veitch, Jean Paul Vonsattel, Nancy S Wexler, Norman Arnheim, Sarah J Augood. Hum Mol Genet 2007
21
MSH3 polymorphisms and protein levels affect CAG repeat instability in Huntington's disease mice.
Stéphanie Tomé, Kevin Manley, Jodie P Simard, Greg W Clark, Meghan M Slean, Meera Swami, Peggy F Shelbourne, Elisabeth R M Tillier, Darren G Monckton, Anne Messer,[...]. PLoS Genet 2013
Stéphanie Tomé, Kevin Manley, Jodie P Simard, Greg W Clark, Meghan M Slean, Meera Swami, Peggy F Shelbourne, Elisabeth R M Tillier, Darren G Monckton, Anne Messer,[...]. PLoS Genet 2013
25
Somatic and gonadal mosaicism of the Huntington disease gene CAG repeat in brain and sperm.
H Telenius, B Kremer, Y P Goldberg, J Theilmann, S E Andrew, J Zeisler, S Adam, C Greenberg, E J Ives, L A Clarke. Nat Genet 1994
H Telenius, B Kremer, Y P Goldberg, J Theilmann, S E Andrew, J Zeisler, S Adam, C Greenberg, E J Ives, L A Clarke. Nat Genet 1994
20
CREB-binding protein modulates repeat instability in a Drosophila model for polyQ disease.
Joonil Jung, Nancy Bonini. Science 2007
Joonil Jung, Nancy Bonini. Science 2007
20
MSH2 ATPase domain mutation affects CTG*CAG repeat instability in transgenic mice.
Stéphanie Tomé, Ian Holt, Winfried Edelmann, Glenn E Morris, Arnold Munnich, Christopher E Pearson, Geneviève Gourdon. PLoS Genet 2009
Stéphanie Tomé, Ian Holt, Winfried Edelmann, Glenn E Morris, Arnold Munnich, Christopher E Pearson, Geneviève Gourdon. PLoS Genet 2009
30
Slipped (CTG)*(CAG) repeats can be correctly repaired, escape repair or undergo error-prone repair.
Gagan B Panigrahi, Rachel Lau, S Erin Montgomery, Michelle R Leonard, Christopher E Pearson. Nat Struct Mol Biol 2005
Gagan B Panigrahi, Rachel Lau, S Erin Montgomery, Michelle R Leonard, Christopher E Pearson. Nat Struct Mol Biol 2005
19
Cockayne syndrome B protein antagonizes OGG1 in modulating CAG repeat length in vivo.
Irina V Kovtun, Kurt O Johnson, Cynthia T McMurray. Aging (Albany NY) 2011
Irina V Kovtun, Kurt O Johnson, Cynthia T McMurray. Aging (Albany NY) 2011
50
Neil1 is a genetic modifier of somatic and germline CAG trinucleotide repeat instability in R6/1 mice.
Linda Møllersen, Alexander D Rowe, Jennifer L Illuzzi, Gunn A Hildrestrand, Katharina J Gerhold, Linda Tveterås, Anja Bjølgerud, David M Wilson, Magnar Bjørås, Arne Klungland. Hum Mol Genet 2012
Linda Møllersen, Alexander D Rowe, Jennifer L Illuzzi, Gunn A Hildrestrand, Katharina J Gerhold, Linda Tveterås, Anja Bjølgerud, David M Wilson, Magnar Bjørås, Arne Klungland. Hum Mol Genet 2012
36
18
Histone deacetylase complexes promote trinucleotide repeat expansions.
Kim Debacker, Aisling Frizzell, Olive Gleeson, Lucy Kirkham-McCarthy, Tony Mertz, Robert S Lahue. PLoS Biol 2012
Kim Debacker, Aisling Frizzell, Olive Gleeson, Lucy Kirkham-McCarthy, Tony Mertz, Robert S Lahue. PLoS Biol 2012
37
MutSβ and histone deacetylase complexes promote expansions of trinucleotide repeats in human cells.
Anne-Marie M Gannon, Aisling Frizzell, Evan Healy, Robert S Lahue. Nucleic Acids Res 2012
Anne-Marie M Gannon, Aisling Frizzell, Evan Healy, Robert S Lahue. Nucleic Acids Res 2012
35
R loops stimulate genetic instability of CTG.CAG repeats.
Yunfu Lin, Sharon Y R Dent, John H Wilson, Robert D Wells, Marek Napierala. Proc Natl Acad Sci U S A 2010
Yunfu Lin, Sharon Y R Dent, John H Wilson, Robert D Wells, Marek Napierala. Proc Natl Acad Sci U S A 2010
17
The mismatch repair protein MSH2 is rate limiting for repeat expansion in a fragile X premutation mouse model.
Rachel Adihe Lokanga, Xiao-Nan Zhao, Karen Usdin. Hum Mutat 2014
Rachel Adihe Lokanga, Xiao-Nan Zhao, Karen Usdin. Hum Mutat 2014
29
Repeat instability during DNA repair: Insights from model systems.
Karen Usdin, Nealia C M House, Catherine H Freudenreich. Crit Rev Biochem Mol Biol 2015
Karen Usdin, Nealia C M House, Catherine H Freudenreich. Crit Rev Biochem Mol Biol 2015
17
Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation.
L Mangiarini, K Sathasivam, A Mahal, R Mott, M Seller, G P Bates. Nat Genet 1997
L Mangiarini, K Sathasivam, A Mahal, R Mott, M Seller, G P Bates. Nat Genet 1997
16
Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair.
Hyun-Min Kim, Vidhya Narayanan, Piotr A Mieczkowski, Thomas D Petes, Maria M Krasilnikova, Sergei M Mirkin, Kirill S Lobachev. EMBO J 2008
Hyun-Min Kim, Vidhya Narayanan, Piotr A Mieczkowski, Thomas D Petes, Maria M Krasilnikova, Sergei M Mirkin, Kirill S Lobachev. EMBO J 2008
20
The mismatch repair system protects against intergenerational GAA repeat instability in a Friedreich ataxia mouse model.
Vahid Ezzatizadeh, Ricardo Mouro Pinto, Chiranjeevi Sandi, Madhavi Sandi, Sahar Al-Mahdawi, Hein Te Riele, Mark A Pook. Neurobiol Dis 2012
Vahid Ezzatizadeh, Ricardo Mouro Pinto, Chiranjeevi Sandi, Madhavi Sandi, Sahar Al-Mahdawi, Hein Te Riele, Mark A Pook. Neurobiol Dis 2012
36
Role of mismatch repair enzymes in GAA·TTC triplet-repeat expansion in Friedreich ataxia induced pluripotent stem cells.
Jintang Du, Erica Campau, Elisabetta Soragni, Sherman Ku, James W Puckett, Peter B Dervan, Joel M Gottesfeld. J Biol Chem 2012
Jintang Du, Erica Campau, Elisabetta Soragni, Sherman Ku, James W Puckett, Peter B Dervan, Joel M Gottesfeld. J Biol Chem 2012
20
Msh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in mice.
Marina Kovalenko, Ella Dragileva, Jason St Claire, Tammy Gillis, Jolene R Guide, Jaclyn New, Hualing Dong, Raju Kucherlapati, Melanie H Kucherlapati, Michelle E Ehrlich,[...]. PLoS One 2012
Marina Kovalenko, Ella Dragileva, Jason St Claire, Tammy Gillis, Jolene R Guide, Jaclyn New, Hualing Dong, Raju Kucherlapati, Melanie H Kucherlapati, Michelle E Ehrlich,[...]. PLoS One 2012
36
Dnmt1 deficiency promotes CAG repeat expansion in the mouse germline.
Vincent Dion, Yunfu Lin, Leroy Hubert, Robert A Waterland, John H Wilson. Hum Mol Genet 2008
Vincent Dion, Yunfu Lin, Leroy Hubert, Robert A Waterland, John H Wilson. Hum Mol Genet 2008
23
Expansion and length-dependent fragility of CTG repeats in yeast.
C H Freudenreich, S M Kantrow, V A Zakian. Science 1998
C H Freudenreich, S M Kantrow, V A Zakian. Science 1998
15
Features of trinucleotide repeat instability in vivo.
Irina V Kovtun, Cynthia T McMurray. Cell Res 2008
Irina V Kovtun, Cynthia T McMurray. Cell Res 2008
15
Huntington disease expansion mutations in humans can occur before meiosis is completed.
Song-Ro Yoon, Louis Dubeau, Margot de Young, Nancy S Wexler, Norman Arnheim. Proc Natl Acad Sci U S A 2003
Song-Ro Yoon, Louis Dubeau, Margot de Young, Nancy S Wexler, Norman Arnheim. Proc Natl Acad Sci U S A 2003
19
Variation of the CGG repeat at the fragile X site results in genetic instability: resolution of the Sherman paradox.
Y H Fu, D P Kuhl, A Pizzuti, M Pieretti, J S Sutcliffe, S Richards, A J Verkerk, J J Holden, R G Fenwick, S T Warren. Cell 1991
Y H Fu, D P Kuhl, A Pizzuti, M Pieretti, J S Sutcliffe, S Richards, A J Verkerk, J J Holden, R G Fenwick, S T Warren. Cell 1991
15
Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instability.
M T Fortune, C Vassilopoulos, M I Coolbaugh, M J Siciliano, D G Monckton. Hum Mol Genet 2000
M T Fortune, C Vassilopoulos, M I Coolbaugh, M J Siciliano, D G Monckton. Hum Mol Genet 2000
15
Hijacking of the mismatch repair system to cause CAG expansion and cell death in neurodegenerative disease.
Cynthia T McMurray. DNA Repair (Amst) 2008
Cynthia T McMurray. DNA Repair (Amst) 2008
24
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