J Y Wu, L Feng, H T Park, N Havlioglu, L Wen, H Tang, K B Bacon, Jiang Zh, Zhang Xc, Y Rao. Nature 2001
Times Cited: 336
Times Cited: 336
Times Cited
Times Co-cited
Similarity
Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.
K Brose, K S Bland, K H Wang, D Arnott, W Henzel, C S Goodman, M Tessier-Lavigne, T Kidd. Cell 1999
K Brose, K S Bland, K H Wang, D Arnott, W Henzel, C S Goodman, M Tessier-Lavigne, T Kidd. Cell 1999
39
Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.
K Wong, X R Ren, Y Z Huang, Y Xie, G Liu, H Saito, H Tang, L Wen, S M Brady-Kalnay, L Mei,[...]. Cell 2001
K Wong, X R Ren, Y Z Huang, Y Xie, G Liu, H Saito, H Tang, L Wen, S M Brady-Kalnay, L Mei,[...]. Cell 2001
26
Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity.
Biao Wang, Yang Xiao, Bei Bei Ding, Na Zhang, Xiao bin Yuan, Lü Gui, Kai Xian Qian, Shumin Duan, Zhengjun Chen, Yi Rao,[...]. Cancer Cell 2003
Biao Wang, Yang Xiao, Bei Bei Ding, Na Zhang, Xiao bin Yuan, Lü Gui, Kai Xian Qian, Shumin Duan, Zhengjun Chen, Yi Rao,[...]. Cancer Cell 2003
25
The axonal repellent, Slit2, inhibits directional migration of circulating neutrophils.
Soumitra Tole, Ilya M Mukovozov, Yi-Wei Huang, Marco A O Magalhaes, Ming Yan, Min Rui Crow, Guang Ying Liu, Chun Xiang Sun, Yves Durocher, Michael Glogauer,[...]. J Leukoc Biol 2009
Soumitra Tole, Ilya M Mukovozov, Yi-Wei Huang, Marco A O Magalhaes, Ming Yan, Min Rui Crow, Guang Ying Liu, Chun Xiang Sun, Yves Durocher, Michael Glogauer,[...]. J Leukoc Biol 2009
36
Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis.
Wei-Jie Zhou, Zhen H Geng, Shan Chi, Wenli Zhang, Xiao-Feng Niu, Shu-Jue Lan, Li Ma, Xuesong Yang, Li-Jing Wang, Yan-Qing Ding,[...]. Cell Res 2011
Wei-Jie Zhou, Zhen H Geng, Shan Chi, Wenli Zhang, Xiao-Feng Niu, Shu-Jue Lan, Li Ma, Xuesong Yang, Li-Jing Wang, Yan-Qing Ding,[...]. Cell Res 2011
21
Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors.
T Kidd, K Brose, K J Mitchell, R D Fetter, M Tessier-Lavigne, C S Goodman, G Tear. Cell 1998
T Kidd, K Brose, K J Mitchell, R D Fetter, M Tessier-Lavigne, C S Goodman, G Tear. Cell 1998
20
Slit-2/Robo-1 modulates the CXCL12/CXCR4-induced chemotaxis of T cells.
Anil Prasad, Zahida Qamri, Jane Wu, Ramesh K Ganju. J Leukoc Biol 2007
Anil Prasad, Zahida Qamri, Jane Wu, Ramesh K Ganju. J Leukoc Biol 2007
23
Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.
Christopher A Jones, Nyall R London, Haoyu Chen, Kye Won Park, Dominique Sauvaget, Rebecca A Stockton, Joshua D Wythe, Wonhee Suh, Frederic Larrieu-Lahargue, Yoh-Suke Mukouyama,[...]. Nat Med 2008
Christopher A Jones, Nyall R London, Haoyu Chen, Kye Won Park, Dominique Sauvaget, Rebecca A Stockton, Joshua D Wythe, Wonhee Suh, Frederic Larrieu-Lahargue, Yoh-Suke Mukouyama,[...]. Nat Med 2008
17
Neuronal repellent Slit2 inhibits dendritic cell migration and the development of immune responses.
Hongbing Guan, Guorui Zu, Yi Xie, Hao Tang, Martin Johnson, Xiaochun Xu, Christophe Kevil, Wen-Cheng Xiong, Craig Elmets, Yi Rao,[...]. J Immunol 2003
Hongbing Guan, Guorui Zu, Yi Xie, Hao Tang, Martin Johnson, Xiaochun Xu, Christophe Kevil, Wen-Cheng Xiong, Craig Elmets, Yi Rao,[...]. J Immunol 2003
22
Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis.
Lukasz Huminiecki, Michael Gorn, Steven Suchting, Richard Poulsom, Roy Bicknell. Genomics 2002
Lukasz Huminiecki, Michael Gorn, Steven Suchting, Richard Poulsom, Roy Bicknell. Genomics 2002
16
Structural insights into the Slit-Robo complex.
Cecile Morlot, Nicole M Thielens, Raimond B G Ravelli, Wieger Hemrika, Roland A Romijn, Piet Gros, Stephen Cusack, Andrew A McCarthy. Proc Natl Acad Sci U S A 2007
Cecile Morlot, Nicole M Thielens, Raimond B G Ravelli, Wieger Hemrika, Roland A Romijn, Piet Gros, Stephen Cusack, Andrew A McCarthy. Proc Natl Acad Sci U S A 2007
16
Robo4 is a vascular-specific receptor that inhibits endothelial migration.
Kye Won Park, Clayton M Morrison, Lise K Sorensen, Christopher A Jones, Yi Rao, Chi-Bin Chien, Jane Y Wu, Lisa D Urness, Dean Y Li. Dev Biol 2003
Kye Won Park, Clayton M Morrison, Lise K Sorensen, Christopher A Jones, Yi Rao, Chi-Bin Chien, Jane Y Wu, Lisa D Urness, Dean Y Li. Dev Biol 2003
16
Slit2 inhibits glioma cell invasion in the brain by suppression of Cdc42 activity.
Jia-Jean Yiin, Bo Hu, Michael J Jarzynka, Haizhong Feng, Kui-Wei Liu, Jane Y Wu, Hsin-I Ma, Shi-Yuan Cheng. Neuro Oncol 2009
Jia-Jean Yiin, Bo Hu, Michael J Jarzynka, Haizhong Feng, Kui-Wei Liu, Jane Y Wu, Hsin-I Ma, Shi-Yuan Cheng. Neuro Oncol 2009
20
SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers.
Ashraf Dallol, Nancy Fernandes Da Silva, Paolo Viacava, John D Minna, Ivan Bieche, Eamonn R Maher, Farida Latif. Cancer Res 2002
Ashraf Dallol, Nancy Fernandes Da Silva, Paolo Viacava, John D Minna, Ivan Bieche, Eamonn R Maher, Farida Latif. Cancer Res 2002
14
Modulation of inflammation by slit protein in vivo in experimental crescentic glomerulonephritis.
John Kanellis, Gabriela E Garcia, Ping Li, Gustavo Parra, Curtis B Wilson, Yi Rao, Suhua Han, C Wayne Smith, Richard J Johnson, Jane Y Wu,[...]. Am J Pathol 2004
John Kanellis, Gabriela E Garcia, Ping Li, Gustavo Parra, Curtis B Wilson, Yi Rao, Suhua Han, C Wayne Smith, Richard J Johnson, Jane Y Wu,[...]. Am J Pathol 2004
30
Directional guidance of neuronal migration in the olfactory system by the protein Slit.
W Wu, K Wong, J Chen, Z Jiang, S Dupuis, J Y Wu, Y Rao. Nature 1999
W Wu, K Wong, J Chen, Z Jiang, S Dupuis, J Y Wu, Y Rao. Nature 1999
13
Slit-2 induces a tumor-suppressive effect by regulating beta-catenin in breast cancer cells.
Anil Prasad, Vikram Paruchuri, Anju Preet, Farida Latif, Ramesh K Ganju. J Biol Chem 2008
Anil Prasad, Vikram Paruchuri, Anju Preet, Farida Latif, Ramesh K Ganju. J Biol Chem 2008
15
Regulation of commissural axon pathfinding by slit and its Robo receptors.
Barry J Dickson, Giorgio F Gilestro. Annu Rev Cell Dev Biol 2006
Barry J Dickson, Giorgio F Gilestro. Annu Rev Cell Dev Biol 2006
13
Slit is the midline repellent for the robo receptor in Drosophila.
T Kidd, K S Bland, C S Goodman. Cell 1999
T Kidd, K S Bland, C S Goodman. Cell 1999
13
Targeting Slit-Roundabout signaling inhibits tumor angiogenesis in chemical-induced squamous cell carcinogenesis.
Li-Jing Wang, Yuan Zhao, Bing Han, Yu-Guang Ma, Jie Zhang, Ding-Ming Yang, Jian-Wen Mao, Fu-Tian Tang, Wei-Dong Li, Yang Yang,[...]. Cancer Sci 2008
Li-Jing Wang, Yuan Zhao, Bing Han, Yu-Guang Ma, Jie Zhang, Ding-Ming Yang, Jian-Wen Mao, Fu-Tian Tang, Wei-Dong Li, Yang Yang,[...]. Cancer Sci 2008
19
SLIT2 attenuation during lung cancer progression deregulates beta-catenin and E-cadherin and associates with poor prognosis.
Ruo-Chia Tseng, Shih-Hua Lee, Han-Shui Hsu, Ben-Han Chen, Wan-Ching Tsai, Ching Tzao, Yi-Ching Wang. Cancer Res 2010
Ruo-Chia Tseng, Shih-Hua Lee, Han-Shui Hsu, Ben-Han Chen, Wan-Ching Tsai, Ching Tzao, Yi-Ching Wang. Cancer Res 2010
13
Promoter hypermethylation-mediated inactivation of multiple Slit-Robo pathway genes in cervical cancer progression.
Gopeshwar Narayan, Chandra Goparaju, Hugo Arias-Pulido, Andreas M Kaufmann, Achim Schneider, Matthias Dürst, Mahesh Mansukhani, Bhavana Pothuri, Vundavalli V Murty. Mol Cancer 2006
Gopeshwar Narayan, Chandra Goparaju, Hugo Arias-Pulido, Andreas M Kaufmann, Achim Schneider, Matthias Dürst, Mahesh Mansukhani, Bhavana Pothuri, Vundavalli V Murty. Mol Cancer 2006
12
Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza.
Nyall R London, Weiquan Zhu, Fernando A Bozza, Matthew C P Smith, Daniel M Greif, Lise K Sorensen, Luming Chen, Yuuki Kaminoh, Aubrey C Chan, Samuel F Passi,[...]. Sci Transl Med 2010
Nyall R London, Weiquan Zhu, Fernando A Bozza, Matthew C P Smith, Daniel M Greif, Lise K Sorensen, Luming Chen, Yuuki Kaminoh, Aubrey C Chan, Samuel F Passi,[...]. Sci Transl Med 2010
12
Frequent epigenetic inactivation of the SLIT2 gene in gliomas.
Ashraf Dallol, Dietmar Krex, Luke Hesson, Charis Eng, Eamonn R Maher, Farida Latif. Oncogene 2003
Ashraf Dallol, Dietmar Krex, Luke Hesson, Charis Eng, Eamonn R Maher, Farida Latif. Oncogene 2003
12
Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons.
H S Li, J H Chen, W Wu, T Fagaly, L Zhou, W Yuan, S Dupuis, Z H Jiang, W Nash, C Gick,[...]. Cell 1999
H S Li, J H Chen, W Wu, T Fagaly, L Zhou, W Yuan, S Dupuis, Z H Jiang, W Nash, C Gick,[...]. Cell 1999
12
Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity.
Christopher A Jones, Naoyuki Nishiya, Nyall R London, Weiquan Zhu, Lise K Sorensen, Aubrey C Chan, Chinten J Lim, Haoyu Chen, Qisheng Zhang, Peter G Schultz,[...]. Nat Cell Biol 2009
Christopher A Jones, Naoyuki Nishiya, Nyall R London, Weiquan Zhu, Lise K Sorensen, Aubrey C Chan, Chinten J Lim, Haoyu Chen, Qisheng Zhang, Peter G Schultz,[...]. Nat Cell Biol 2009
12
Slit2 prevents neutrophil recruitment and renal ischemia-reperfusion injury.
Swasti Chaturvedi, Darren A Yuen, Amandeep Bajwa, Yi-Wei Huang, Christiane Sokollik, Liping Huang, Grace Y Lam, Soumitra Tole, Guang-Ying Liu, Jerry Pan,[...]. J Am Soc Nephrol 2013
Swasti Chaturvedi, Darren A Yuen, Amandeep Bajwa, Yi-Wei Huang, Christiane Sokollik, Liping Huang, Grace Y Lam, Soumitra Tole, Guang-Ying Liu, Jerry Pan,[...]. J Am Soc Nephrol 2013
28
Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation.
Bu-Qing Ye, Zhen H Geng, Li Ma, Jian-Guo Geng. J Immunol 2010
Bu-Qing Ye, Zhen H Geng, Li Ma, Jian-Guo Geng. J Immunol 2010
23
Repulsive axon guidance molecule Slit3 is a novel angiogenic factor.
Bing Zhang, Ursula M Dietrich, Jian-Guo Geng, Roy Bicknell, Jeffrey D Esko, Lianchun Wang. Blood 2009
Bing Zhang, Ursula M Dietrich, Jian-Guo Geng, Roy Bicknell, Jeffrey D Esko, Lianchun Wang. Blood 2009
11
Switching repulsion to attraction: changing responses to slit during transition in mesoderm migration.
S G Kramer, T Kidd, J H Simpson, C S Goodman. Science 2001
S G Kramer, T Kidd, J H Simpson, C S Goodman. Science 2001
11
Slit protein-mediated inhibition of CXCR4-induced chemotactic and chemoinvasive signaling pathways in breast cancer cells.
Anil Prasad, Aaron Z Fernandis, Yi Rao, Ramesh K Ganju. J Biol Chem 2004
Anil Prasad, Aaron Z Fernandis, Yi Rao, Ramesh K Ganju. J Biol Chem 2004
11
Slit2-Robo4 pathway modulates lipopolysaccharide-induced endothelial inflammation and its expression is dysregulated during endotoxemia.
Helong Zhao, Appakkudal R Anand, Ramesh K Ganju. J Immunol 2014
Helong Zhao, Appakkudal R Anand, Ramesh K Ganju. J Immunol 2014
18
SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site.
Uta Grieshammer, Le Ma, Andrew S Plump, Fan Wang, Marc Tessier-Lavigne, Gail R Martin. Dev Cell 2004
Uta Grieshammer, Le Ma, Andrew S Plump, Fan Wang, Marc Tessier-Lavigne, Gail R Martin. Dev Cell 2004
10
Deubiquitinating enzyme USP33/VDU1 is required for Slit signaling in inhibiting breast cancer cell migration.
Junichi Yuasa-Kawada, Mariko Kinoshita-Kawada, Yi Rao, Jane Y Wu. Proc Natl Acad Sci U S A 2009
Junichi Yuasa-Kawada, Mariko Kinoshita-Kawada, Yi Rao, Jane Y Wu. Proc Natl Acad Sci U S A 2009
14
SLIT2 axon guidance molecule is frequently inactivated in colorectal cancer and suppresses growth of colorectal carcinoma cells.
Ashraf Dallol, Dion Morton, Eamonn R Maher, Farida Latif. Cancer Res 2003
Ashraf Dallol, Dion Morton, Eamonn R Maher, Farida Latif. Cancer Res 2003
10
The neuronal guidance cue Slit2 induces targeted migration and may play a role in brain metastasis of breast cancer cells.
Bernd C Schmid, Günther A Rezniczek, Gerhild Fabjani, Toshiyuki Yoneda, Sepp Leodolter, Robert Zeillinger. Breast Cancer Res Treat 2007
Bernd C Schmid, Günther A Rezniczek, Gerhild Fabjani, Toshiyuki Yoneda, Sepp Leodolter, Robert Zeillinger. Breast Cancer Res Treat 2007
13
The chemorepellent Slit3 promotes monocyte migration.
Sacha B Geutskens, Peter L Hordijk, Paula B van Hennik. J Immunol 2010
Sacha B Geutskens, Peter L Hordijk, Paula B van Hennik. J Immunol 2010
25
Activation of Robo1 signaling of breast cancer cells by Slit2 from stromal fibroblast restrains tumorigenesis via blocking PI3K/Akt/β-catenin pathway.
Po-Hao Chang, Wendy W Hwang-Verslues, Yi-Cheng Chang, Chun-Chin Chen, Michael Hsiao, Yung-Ming Jeng, King-Jen Chang, Eva Y-H P Lee, Jin-Yuh Shew, Wen-Hwa Lee. Cancer Res 2012
Po-Hao Chang, Wendy W Hwang-Verslues, Yi-Cheng Chang, Chun-Chin Chen, Michael Hsiao, Yung-Ming Jeng, King-Jen Chang, Eva Y-H P Lee, Jin-Yuh Shew, Wen-Hwa Lee. Cancer Res 2012
9
Active involvement of Robo1 and Robo4 in filopodia formation and endothelial cell motility mediated via WASP and other actin nucleation-promoting factors.
Helen Sheldon, Maud Andre, John A Legg, Paul Heal, John M Herbert, Richard Sainson, Anshula S Sharma, Jan K Kitajewski, Victoria L Heath, Roy Bicknell. FASEB J 2009
Helen Sheldon, Maud Andre, John A Legg, Paul Heal, John M Herbert, Richard Sainson, Anshula S Sharma, Jan K Kitajewski, Victoria L Heath, Roy Bicknell. FASEB J 2009
9
Slit proteins: molecular guidance cues for cells ranging from neurons to leukocytes.
Kit Wong, Hwan Tae Park, Jane Y Wu, Yi Rao. Curr Opin Genet Dev 2002
Kit Wong, Hwan Tae Park, Jane Y Wu, Yi Rao. Curr Opin Genet Dev 2002
9
Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor.
G J Bashaw, T Kidd, D Murray, T Pawson, C S Goodman. Cell 2000
G J Bashaw, T Kidd, D Murray, T Pawson, C S Goodman. Cell 2000
9
Slit-Robo signaling mediates lymphangiogenesis and promotes tumor lymphatic metastasis.
Xiao-Mei Yang, Hai-Xiong Han, Fei Sui, Yu-Min Dai, Ming Chen, Jian-Guo Geng. Biochem Biophys Res Commun 2010
Xiao-Mei Yang, Hai-Xiong Han, Fei Sui, Yu-Min Dai, Ming Chen, Jian-Guo Geng. Biochem Biophys Res Commun 2010
16
Novel roles for Slits and netrins: axon guidance cues as anticancer targets?
Patrick Mehlen, Céline Delloye-Bourgeois, Alain Chédotal. Nat Rev Cancer 2011
Patrick Mehlen, Céline Delloye-Bourgeois, Alain Chédotal. Nat Rev Cancer 2011
9
Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization.
Nicolas Rama, Alexandre Dubrac, Thomas Mathivet, Róisín-Ana Ní Chárthaigh, Gael Genet, Brunella Cristofaro, Laurence Pibouin-Fragner, Le Ma, Anne Eichmann, Alain Chédotal. Nat Med 2015
Nicolas Rama, Alexandre Dubrac, Thomas Mathivet, Róisín-Ana Ní Chárthaigh, Gael Genet, Brunella Cristofaro, Laurence Pibouin-Fragner, Le Ma, Anne Eichmann, Alain Chédotal. Nat Med 2015
9
Signaling switch of the axon guidance receptor Robo3 during vertebrate evolution.
Pavol Zelina, Heike Blockus, Yvrick Zagar, Amélie Péres, François Friocourt, Zhuhao Wu, Nicolas Rama, Coralie Fouquet, Erhard Hohenester, Marc Tessier-Lavigne,[...]. Neuron 2014
Pavol Zelina, Heike Blockus, Yvrick Zagar, Amélie Péres, François Friocourt, Zhuhao Wu, Nicolas Rama, Coralie Fouquet, Erhard Hohenester, Marc Tessier-Lavigne,[...]. Neuron 2014
9
Epigenetic inactivation of SLIT3 and SLIT1 genes in human cancers.
R E Dickinson, A Dallol, I Bieche, D Krex, D Morton, E R Maher, F Latif. Br J Cancer 2004
R E Dickinson, A Dallol, I Bieche, D Krex, D Morton, E R Maher, F Latif. Br J Cancer 2004
8
The SLIT-ROBO pathway: a regulator of cell function with implications for the reproductive system.
Rachel E Dickinson, W Colin Duncan. Reproduction 2010
Rachel E Dickinson, W Colin Duncan. Reproduction 2010
9
The mouse SLIT family: secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidance.
W Yuan, L Zhou, J H Chen, J Y Wu, Y Rao, D M Ornitz. Dev Biol 1999
W Yuan, L Zhou, J H Chen, J Y Wu, Y Rao, D M Ornitz. Dev Biol 1999
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.