M C McFadyen, H L McLeod, F C Jackson, W T Melvin, J Doehmer, G I Murray. Biochem Pharmacol 2001
Times Cited: 133
Times Cited: 133
Times Cited
Times Co-cited
Similarity
Tumor-specific expression of cytochrome P450 CYP1B1.
G I Murray, M C Taylor, M C McFadyen, J A McKay, W F Greenlee, M D Burke, W T Melvin. Cancer Res 1997
G I Murray, M C Taylor, M C McFadyen, J A McKay, W F Greenlee, M D Burke, W T Melvin. Cancer Res 1997
39
Human CYP1B1 and anticancer agent metabolism: mechanism for tumor-specific drug inactivation?
B Rochat, J M Morsman, G I Murray, W D Figg, H L McLeod. J Pharmacol Exp Ther 2001
B Rochat, J M Morsman, G I Murray, W D Figg, H L McLeod. J Pharmacol Exp Ther 2001
37
Design and Synthesis of New α-Naphthoflavones as Cytochrome P450 (CYP) 1B1 Inhibitors To Overcome Docetaxel-Resistance Associated with CYP1B1 Overexpression.
Jiahua Cui, Qingqing Meng, Xu Zhang, Qing Cui, Wen Zhou, Shaoshun Li. J Med Chem 2015
Jiahua Cui, Qingqing Meng, Xu Zhang, Qing Cui, Wen Zhou, Shaoshun Li. J Med Chem 2015
44
Structural characterization of the complex between alpha-naphthoflavone and human cytochrome P450 1B1.
An Wang, Uzen Savas, C David Stout, Eric F Johnson. J Biol Chem 2011
An Wang, Uzen Savas, C David Stout, Eric F Johnson. J Biol Chem 2011
23
Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer.
M C McFadyen, M E Cruickshank, I D Miller, H L McLeod, W T Melvin, N E Haites, D Parkin, G I Murray. Br J Cancer 2001
M C McFadyen, M E Cruickshank, I D Miller, H L McLeod, W T Melvin, N E Haites, D Parkin, G I Murray. Br J Cancer 2001
21
17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1B1.
C L Hayes, D C Spink, B C Spink, J Q Cao, N J Walker, T R Sutter. Proc Natl Acad Sci U S A 1996
C L Hayes, D C Spink, B C Spink, J Q Cao, N J Walker, T R Sutter. Proc Natl Acad Sci U S A 1996
20
Regulation, function, and tissue-specific expression of cytochrome P450 CYP1B1.
G I Murray, W T Melvin, W F Greenlee, M D Burke. Annu Rev Pharmacol Toxicol 2001
G I Murray, W T Melvin, W F Greenlee, M D Burke. Annu Rev Pharmacol Toxicol 2001
18
Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.
T Shimada, C L Hayes, H Yamazaki, S Amin, S S Hecht, F P Guengerich, T R Sutter. Cancer Res 1996
T Shimada, C L Hayes, H Yamazaki, S Amin, S S Hecht, F P Guengerich, T R Sutter. Cancer Res 1996
18
Docetaxel (Taxotere) is not metabolized by recombinant human CYP1B1 in vitro, but acts as an effector of this isozyme.
Bruno Bournique, Audrey Lemarié. Drug Metab Dispos 2002
Bruno Bournique, Audrey Lemarié. Drug Metab Dispos 2002
35
CYP1B1 expression is induced by docetaxel: effect on cell viability and drug resistance.
V G Martinez, R O'Connor, Y Liang, M Clynes. Br J Cancer 2008
V G Martinez, R O'Connor, Y Liang, M Clynes. Br J Cancer 2008
34
Cytochrome P450 1B1 is overexpressed and regulated by hypomethylation in prostate cancer.
Takashi Tokizane, Hiroaki Shiina, Mikio Igawa, Hideki Enokida, Shinji Urakami, Toshifumi Kawakami, Tatsuya Ogishima, Steven T Okino, Long-Cheng Li, Yuichiro Tanaka,[...]. Clin Cancer Res 2005
Takashi Tokizane, Hiroaki Shiina, Mikio Igawa, Hideki Enokida, Shinji Urakami, Toshifumi Kawakami, Tatsuya Ogishima, Steven T Okino, Long-Cheng Li, Yuichiro Tanaka,[...]. Clin Cancer Res 2005
16
Pharmacogenetics and regulation of human cytochrome P450 1B1: implications in hormone-mediated tumor metabolism and a novel target for therapeutic intervention.
Tristan M Sissung, Douglas K Price, Alex Sparreboom, William D Figg. Mol Cancer Res 2006
Tristan M Sissung, Douglas K Price, Alex Sparreboom, William D Figg. Mol Cancer Res 2006
15
Association of the CYP1B1*3 allele with survival in patients with prostate cancer receiving docetaxel.
Tristan M Sissung, Romano Danesi, Douglas K Price, Seth M Steinberg, Ronald de Wit, Muhammad Zahid, Nilesh Gaikwad, Ercole Cavalieri, William L Dahut, Dan L Sackett,[...]. Mol Cancer Ther 2008
Tristan M Sissung, Romano Danesi, Douglas K Price, Seth M Steinberg, Ronald de Wit, Muhammad Zahid, Nilesh Gaikwad, Ercole Cavalieri, William L Dahut, Dan L Sackett,[...]. Mol Cancer Ther 2008
21
Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2.
Stefaan Sansen, Jason K Yano, Rosamund L Reynald, Guillaume A Schoch, Keith J Griffin, C David Stout, Eric F Johnson. J Biol Chem 2007
Stefaan Sansen, Jason K Yano, Rosamund L Reynald, Guillaume A Schoch, Keith J Griffin, C David Stout, Eric F Johnson. J Biol Chem 2007
15
44
Complete cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2.
T R Sutter, Y M Tang, C L Hayes, Y Y Wo, E W Jabs, X Li, H Yin, C W Cody, W F Greenlee. J Biol Chem 1994
T R Sutter, Y M Tang, C L Hayes, Y Y Wo, E W Jabs, X Li, H Yin, C W Cody, W F Greenlee. J Biol Chem 1994
14
Human cytochrome P450 1A1 structure and utility in understanding drug and xenobiotic metabolism.
Agnes A Walsh, Grazyna D Szklarz, Emily E Scott. J Biol Chem 2013
Agnes A Walsh, Grazyna D Szklarz, Emily E Scott. J Biol Chem 2013
14
Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines.
Neill J Horley, Kenneth J M Beresford, Tarun Chawla, Glen J P McCann, Ketan C Ruparelia, Linda Gatchie, Vinay R Sonawane, Ibidapo S Williams, Hoon L Tan, Prashant Joshi,[...]. Eur J Med Chem 2017
Neill J Horley, Kenneth J M Beresford, Tarun Chawla, Glen J P McCann, Ketan C Ruparelia, Linda Gatchie, Vinay R Sonawane, Ibidapo S Williams, Hoon L Tan, Prashant Joshi,[...]. Eur J Med Chem 2017
45
Pharmacogenetic analysis of paclitaxel transport and metabolism genes in breast cancer.
S Marsh, G Somlo, X Li, P Frankel, C R King, W D Shannon, H L McLeod, T W Synold. Pharmacogenomics J 2007
S Marsh, G Somlo, X Li, P Frankel, C R King, W D Shannon, H L McLeod, T W Synold. Pharmacogenomics J 2007
13
Selective inhibition of methoxyflavonoids on human CYP1B1 activity.
Hitomi Takemura, Toshimasa Itoh, Keiko Yamamoto, Hiroyuki Sakakibara, Kayoko Shimoi. Bioorg Med Chem 2010
Hitomi Takemura, Toshimasa Itoh, Keiko Yamamoto, Hiroyuki Sakakibara, Kayoko Shimoi. Bioorg Med Chem 2010
21
Proteasomal degradation of human CYP1B1: effect of the Asn453Ser polymorphism on the post-translational regulation of CYP1B1 expression.
Silvio Bandiera, Simone Weidlich, Volker Harth, Peter Broede, Yun Ko, Thomas Friedberg. Mol Pharmacol 2005
Silvio Bandiera, Simone Weidlich, Volker Harth, Peter Broede, Yun Ko, Thomas Friedberg. Mol Pharmacol 2005
16
Cytochrome P450 1B1 (CYP1B1) pharmacogenetics: association of polymorphisms with functional differences in estrogen hydroxylation activity.
I H Hanna, S Dawling, N Roodi, F P Guengerich, F F Parl. Cancer Res 2000
I H Hanna, S Dawling, N Roodi, F P Guengerich, F F Parl. Cancer Res 2000
12
CYP1B1 enhances the resistance of epithelial ovarian cancer cells to paclitaxel in vivo and in vitro.
Zhuangyan Zhu, Yaqin Mu, Caixia Qi, Jian Wang, Guoping Xi, Juncheng Guo, Ruoran Mi, Fuxi Zhao. Int J Mol Med 2015
Zhuangyan Zhu, Yaqin Mu, Caixia Qi, Jian Wang, Guoping Xi, Juncheng Guo, Ruoran Mi, Fuxi Zhao. Int J Mol Med 2015
33
Human CYP1B1 is regulated by estradiol via estrogen receptor.
Yuki Tsuchiya, Miki Nakajima, Satoru Kyo, Taro Kanaya, Masaki Inoue, Tsuyoshi Yokoi. Cancer Res 2004
Yuki Tsuchiya, Miki Nakajima, Satoru Kyo, Taro Kanaya, Masaki Inoue, Tsuyoshi Yokoi. Cancer Res 2004
11
MicroRNA regulates the expression of human cytochrome P450 1B1.
Yuki Tsuchiya, Miki Nakajima, Shingo Takagi, Takao Taniya, Tsuyoshi Yokoi. Cancer Res 2006
Yuki Tsuchiya, Miki Nakajima, Shingo Takagi, Takao Taniya, Tsuyoshi Yokoi. Cancer Res 2006
11
Targeting cytochrome P450 enzymes: a new approach in anti-cancer drug development.
Robert D Bruno, Vincent C O Njar. Bioorg Med Chem 2007
Robert D Bruno, Vincent C O Njar. Bioorg Med Chem 2007
11
Molecular origin of cancer: catechol estrogen-3,4-quinones as endogenous tumor initiators.
E L Cavalieri, D E Stack, P D Devanesan, R Todorovic, I Dwivedy, S Higginbotham, S L Johansson, K D Patil, M L Gross, J K Gooden,[...]. Proc Natl Acad Sci U S A 1997
E L Cavalieri, D E Stack, P D Devanesan, R Todorovic, I Dwivedy, S Higginbotham, S L Johansson, K D Patil, M L Gross, J K Gooden,[...]. Proc Natl Acad Sci U S A 1997
11
The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis.
Daniel W Nebert, Timothy P Dalton. Nat Rev Cancer 2006
Daniel W Nebert, Timothy P Dalton. Nat Rev Cancer 2006
11
Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids.
Vasilis P Androutsopoulos, Athanasios Papakyriakou, Dionisios Vourloumis, Demetrios A Spandidos. Bioorg Med Chem 2011
Vasilis P Androutsopoulos, Athanasios Papakyriakou, Dionisios Vourloumis, Demetrios A Spandidos. Bioorg Med Chem 2011
15
Cytochrome P450 1B1: a target for inhibition in anticarcinogenesis strategies.
F Peter Guengerich, Young-Jin Chun, Donghak Kim, Elizabeth M J Gillam, Tsutomu Shimada. Mutat Res 2003
F Peter Guengerich, Young-Jin Chun, Donghak Kim, Elizabeth M J Gillam, Tsutomu Shimada. Mutat Res 2003
11
Catalytic properties of polymorphic human cytochrome P450 1B1 variants.
T Shimada, J Watanabe, K Kawajiri, T R Sutter, F P Guengerich, E M Gillam, K Inoue. Carcinogenesis 1999
T Shimada, J Watanabe, K Kawajiri, T R Sutter, F P Guengerich, E M Gillam, K Inoue. Carcinogenesis 1999
10
Cytochrome P450 1B1: a novel anticancer therapeutic target.
Morag C E McFadyen, Graeme I Murray. Future Oncol 2005
Morag C E McFadyen, Graeme I Murray. Future Oncol 2005
17
Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention.
Vasilis P Androutsopoulos, Aristidis M Tsatsakis, Demetrios A Spandidos. BMC Cancer 2009
Vasilis P Androutsopoulos, Aristidis M Tsatsakis, Demetrios A Spandidos. BMC Cancer 2009
10
Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms.
Anthony J Lee, May Xiaoxin Cai, Paul E Thomas, Allan H Conney, Bao Ting Zhu. Endocrinology 2003
Anthony J Lee, May Xiaoxin Cai, Paul E Thomas, Allan H Conney, Bao Ting Zhu. Endocrinology 2003
10
Selectivity of polycyclic inhibitors for human cytochrome P450s 1A1, 1A2, and 1B1.
T Shimada, H Yamazaki, M Foroozesh, N E Hopkins, W L Alworth, F P Guengerich. Chem Res Toxicol 1998
T Shimada, H Yamazaki, M Foroozesh, N E Hopkins, W L Alworth, F P Guengerich. Chem Res Toxicol 1998
10
Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1B1.
H Doostdar, M D Burke, R T Mayer. Toxicology 2000
H Doostdar, M D Burke, R T Mayer. Toxicology 2000
10
10
Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation.
Ulrich M Zanger, Matthias Schwab. Pharmacol Ther 2013
Ulrich M Zanger, Matthias Schwab. Pharmacol Ther 2013
10
Human cytochromes P450 in health and disease.
Daniel W Nebert, Kjell Wikvall, Walter L Miller. Philos Trans R Soc Lond B Biol Sci 2013
Daniel W Nebert, Kjell Wikvall, Walter L Miller. Philos Trans R Soc Lond B Biol Sci 2013
10
Discovery of cytochrome P450 1B1 inhibitors as new promising anti-cancer agents.
Young-Jin Chun, Sanghee Kim. Med Res Rev 2003
Young-Jin Chun, Sanghee Kim. Med Res Rev 2003
15
In situ hybridization and immunohistochemical analysis of cytochrome P450 1B1 expression in human normal tissues.
L Muskhelishvili, P A Thompson, D F Kusewitt, C Wang, F F Kadlubar. J Histochem Cytochem 2001
L Muskhelishvili, P A Thompson, D F Kusewitt, C Wang, F F Kadlubar. J Histochem Cytochem 2001
9
Cytochrome P450-mediated metabolism of estrogens and its regulation in human.
Yuki Tsuchiya, Miki Nakajima, Tsuyoshi Yokoi. Cancer Lett 2005
Yuki Tsuchiya, Miki Nakajima, Tsuyoshi Yokoi. Cancer Lett 2005
9
Cytochrome P450 CYP1B1 activity in renal cell carcinoma.
M C E McFadyen, W T Melvin, G I Murray. Br J Cancer 2004
M C E McFadyen, W T Melvin, G I Murray. Br J Cancer 2004
20
CYP1B1 and hormone-induced cancer.
Ketan Gajjar, Pierre L Martin-Hirsch, Francis L Martin. Cancer Lett 2012
Ketan Gajjar, Pierre L Martin-Hirsch, Francis L Martin. Cancer Lett 2012
10
Dietary flavonoids in cancer therapy and prevention: substrates and inhibitors of cytochrome P450 CYP1 enzymes.
Vasilis P Androutsopoulos, Athanasios Papakyriakou, Dionisios Vourloumis, Aristidis M Tsatsakis, Demetrios A Spandidos. Pharmacol Ther 2010
Vasilis P Androutsopoulos, Athanasios Papakyriakou, Dionisios Vourloumis, Aristidis M Tsatsakis, Demetrios A Spandidos. Pharmacol Ther 2010
9
Design, synthesis, and discovery of novel trans-stilbene analogues as potent and selective human cytochrome P450 1B1 inhibitors.
Sanghee Kim, Hyojin Ko, Jae Eun Park, Sungkyu Jung, Sang Kwang Lee, Young-Jin Chun. J Med Chem 2002
Sanghee Kim, Hyojin Ko, Jae Eun Park, Sungkyu Jung, Sang Kwang Lee, Young-Jin Chun. J Med Chem 2002
9
Inhibitors and prodrugs targeting CYP1: a novel approach in cancer prevention and therapy.
Jiahua Cui, Shaoshun Li. Curr Med Chem 2014
Jiahua Cui, Shaoshun Li. Curr Med Chem 2014
20
Flavonoids and Naphthoflavonoids: Wider Roles in the Modulation of Cytochrome P450 Family 1 Enzymes.
Jinyun Dong, Qijing Zhang, Qing Cui, Guang Huang, Xiaoyan Pan, Shaoshun Li. ChemMedChem 2016
Jinyun Dong, Qijing Zhang, Qing Cui, Guang Huang, Xiaoyan Pan, Shaoshun Li. ChemMedChem 2016
31
Targeting Cytochrome P450 (CYP) 1B1 Enzyme with Four Series of A-Ring Substituted Estrane Derivatives: Design, Synthesis, Inhibitory Activity, and Selectivity.
Raphaël Dutour, Jenny Roy, Francisco Cortés-Benítez, René Maltais, Donald Poirier. J Med Chem 2018
Raphaël Dutour, Jenny Roy, Francisco Cortés-Benítez, René Maltais, Donald Poirier. J Med Chem 2018
42
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.