C Zuccato, A Ciammola, D Rigamonti, B R Leavitt, D Goffredo, L Conti, M E MacDonald, R M Friedlander, V Silani, M R Hayden, T Timmusk, S Sipione, E Cattaneo. Science 2001
Times Cited: 932
Times Cited: 932
Times Cited
Times Co-cited
Similarity
40
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
30
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
21
Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease.
Josep M Canals, José R Pineda, Jesús F Torres-Peraza, Miquel Bosch, Raquel Martín-Ibañez, M Teresa Muñoz, Guadalupe Mengod, Patrik Ernfors, Jordi Alberch. J Neurosci 2004
Josep M Canals, José R Pineda, Jesús F Torres-Peraza, Miquel Bosch, Raquel Martín-Ibañez, M Teresa Muñoz, Guadalupe Mengod, Patrik Ernfors, Jordi Alberch. J Neurosci 2004
19
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes.
Chiara Zuccato, Marzia Tartari, Andrea Crotti, Donato Goffredo, Marta Valenza, Luciano Conti, Tiziana Cataudella, Blair R Leavitt, Michael R Hayden, Tõnis Timmusk,[...]. Nat Genet 2003
Chiara Zuccato, Marzia Tartari, Andrea Crotti, Donato Goffredo, Marta Valenza, Luciano Conti, Tiziana Cataudella, Blair R Leavitt, Michael R Hayden, Tõnis Timmusk,[...]. Nat Genet 2003
18
Role of brain-derived neurotrophic factor in Huntington's disease.
Chiara Zuccato, Elena Cattaneo. Prog Neurobiol 2007
Chiara Zuccato, Elena Cattaneo. Prog Neurobiol 2007
17
Anterograde transport of brain-derived neurotrophic factor and its role in the brain.
C A Altar, N Cai, T Bliven, M Juhasz, J M Conner, A L Acheson, R M Lindsay, S J Wiegand. Nature 1997
C A Altar, N Cai, T Bliven, M Juhasz, J M Conner, A L Acheson, R M Lindsay, S J Wiegand. Nature 1997
16
Brain-derived neurotrophic factor in Huntington disease.
I Ferrer, E Goutan, C Marín, M J Rey, T Ribalta. Brain Res 2000
I Ferrer, E Goutan, C Marín, M J Rey, T Ribalta. Brain Res 2000
16
Systematic assessment of BDNF and its receptor levels in human cortices affected by Huntington's disease.
Chiara Zuccato, Manuela Marullo, Paola Conforti, Marcy E MacDonald, Marzia Tartari, Elena Cattaneo. Brain Pathol 2008
Chiara Zuccato, Manuela Marullo, Paola Conforti, Marcy E MacDonald, Marzia Tartari, Elena Cattaneo. Brain Pathol 2008
14
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
13
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
J S Steffan, A Kazantsev, O Spasic-Boskovic, M Greenwald, Y Z Zhu, H Gohler, E E Wanker, G P Bates, D E Housman, L M Thompson. Proc Natl Acad Sci U S A 2000
J S Steffan, A Kazantsev, O Spasic-Boskovic, M Greenwald, Y Z Zhu, H Gohler, E E Wanker, G P Bates, D E Housman, L M Thompson. Proc Natl Acad Sci U S A 2000
12
BDNF overexpression in the forebrain rescues Huntington's disease phenotypes in YAC128 mice.
Yuxiang Xie, Michael R Hayden, Baoji Xu. J Neurosci 2010
Yuxiang Xie, Michael R Hayden, Baoji Xu. J Neurosci 2010
12
Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
12
Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice.
Austen J Milnerwood, Clare M Gladding, Mahmoud A Pouladi, Alexandra M Kaufman, Rochelle M Hines, Jamie D Boyd, Rebecca W Y Ko, Oana C Vasuta, Rona K Graham, Michael R Hayden,[...]. Neuron 2010
Austen J Milnerwood, Clare M Gladding, Mahmoud A Pouladi, Alexandra M Kaufman, Rochelle M Hines, Jamie D Boyd, Rebecca W Y Ko, Oana C Vasuta, Rona K Graham, Michael R Hayden,[...]. Neuron 2010
12
Huntington disease.
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
11
Neuropathological classification of Huntington's disease.
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
11
Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery.
Chiara Zuccato, Daniel Liber, Catarina Ramos, Alessia Tarditi, Dorotea Rigamonti, Marzia Tartari, Marta Valenza, Elena Cattaneo. Pharmacol Res 2005
Chiara Zuccato, Daniel Liber, Catarina Ramos, Alessia Tarditi, Dorotea Rigamonti, Marzia Tartari, Marta Valenza, Elena Cattaneo. Pharmacol Res 2005
11
Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
11
Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.
Liliana B Menalled, Andrea E Kudwa, Sam Miller, Jon Fitzpatrick, Judy Watson-Johnson, Nicole Keating, Melinda Ruiz, Richard Mushlin, William Alosio, Kristi McConnell,[...]. PLoS One 2012
Liliana B Menalled, Andrea E Kudwa, Sam Miller, Jon Fitzpatrick, Judy Watson-Johnson, Nicole Keating, Melinda Ruiz, Richard Mushlin, William Alosio, Kristi McConnell,[...]. PLoS One 2012
11
Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain.
Silvia Ginés, Miquel Bosch, Sonia Marco, Núria Gavaldà, Miguel Díaz-Hernández, José J Lucas, Josep M Canals, Jordi Alberch. Eur J Neurosci 2006
Silvia Ginés, Miquel Bosch, Sonia Marco, Núria Gavaldà, Miguel Díaz-Hernández, José J Lucas, Josep M Canals, Jordi Alberch. Eur J Neurosci 2006
10
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity.
F C Nucifora , M Sasaki, M F Peters, H Huang, J K Cooper, M Yamada, H Takahashi, S Tsuji, J Troncoso, V L Dawson,[...]. Science 2001
F C Nucifora , M Sasaki, M F Peters, H Huang, J K Cooper, M Yamada, H Takahashi, S Tsuji, J Troncoso, V L Dawson,[...]. Science 2001
9
Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
Libin Cui, Hyunkyung Jeong, Fran Borovecki, Christopher N Parkhurst, Naoko Tanese, Dimitri Krainc. Cell 2006
Libin Cui, Hyunkyung Jeong, Fran Borovecki, Christopher N Parkhurst, Naoko Tanese, Dimitri Krainc. Cell 2006
9
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.
Maria Björkqvist, Edward J Wild, Jenny Thiele, Aurelio Silvestroni, Ralph Andre, Nayana Lahiri, Elsa Raibon, Richard V Lee, Caroline L Benn, Denis Soulet,[...]. J Exp Med 2008
Maria Björkqvist, Edward J Wild, Jenny Thiele, Aurelio Silvestroni, Ralph Andre, Nayana Lahiri, Elsa Raibon, Richard V Lee, Caroline L Benn, Denis Soulet,[...]. J Exp Med 2008
9
9
Brain-derived neurotrophic factor in patients with Huntington's disease.
Chiara Zuccato, Manuela Marullo, Barbara Vitali, Alessia Tarditi, Caterina Mariotti, Marta Valenza, Nayana Lahiri, Edward J Wild, Jenny Sassone, Andrea Ciammola,[...]. PLoS One 2011
Chiara Zuccato, Manuela Marullo, Barbara Vitali, Alessia Tarditi, Caterina Mariotti, Marta Valenza, Nayana Lahiri, Edward J Wild, Jenny Sassone, Andrea Ciammola,[...]. PLoS One 2011
10
Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice.
. Nat Neurosci 2017
. Nat Neurosci 2017
9
Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes.
J Nasir, S B Floresco, J R O'Kusky, V M Diewert, J M Richman, J Zeisler, A Borowski, J D Marth, A G Phillips, M R Hayden. Cell 1995
J Nasir, S B Floresco, J R O'Kusky, V M Diewert, J M Richman, J Zeisler, A Borowski, J D Marth, A G Phillips, M R Hayden. Cell 1995
9
Inactivation of the mouse Huntington's disease gene homolog Hdh.
M P Duyao, A B Auerbach, A Ryan, F Persichetti, G T Barnes, S M McNeil, P Ge, J P Vonsattel, J F Gusella, A L Joyner. Science 1995
M P Duyao, A B Auerbach, A Ryan, F Persichetti, G T Barnes, S M McNeil, P Ge, J P Vonsattel, J F Gusella, A L Joyner. Science 1995
9
Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice.
I Dragatsis, M S Levine, S Zeitlin. Nat Genet 2000
I Dragatsis, M S Levine, S Zeitlin. Nat Genet 2000
9
Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue.
S Zeitlin, J P Liu, D L Chapman, V E Papaioannou, A Efstratiadis. Nat Genet 1995
S Zeitlin, J P Liu, D L Chapman, V E Papaioannou, A Efstratiadis. Nat Genet 1995
9
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
9
Targeting Huntingtin Expression in Patients with Huntington's Disease.
Sarah J Tabrizi, Blair R Leavitt, G Bernhard Landwehrmeyer, Edward J Wild, Carsten Saft, Roger A Barker, Nick F Blair, David Craufurd, Josef Priller, Hugh Rickards,[...]. N Engl J Med 2019
Sarah J Tabrizi, Blair R Leavitt, G Bernhard Landwehrmeyer, Edward J Wild, Carsten Saft, Roger A Barker, Nick F Blair, David Craufurd, Josef Priller, Hugh Rickards,[...]. N Engl J Med 2019
9
N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking.
Adam L Orr, Shihua Li, Chuan-En Wang, He Li, Jianjun Wang, Juan Rong, Xingshun Xu, Pier Giorgio Mastroberardino, J Timothy Greenamyre, Xiao-Jiang Li. J Neurosci 2008
Adam L Orr, Shihua Li, Chuan-En Wang, He Li, Jianjun Wang, Juan Rong, Xingshun Xu, Pier Giorgio Mastroberardino, J Timothy Greenamyre, Xiao-Jiang Li. J Neurosci 2008
8
Mutant Huntingtin alters retrograde transport of TrkB receptors in striatal dendrites.
Géraldine Liot, Diana Zala, Patrick Pla, Guillaume Mottet, Matthieu Piel, Frédéric Saudou. J Neurosci 2013
Géraldine Liot, Diana Zala, Patrick Pla, Guillaume Mottet, Matthieu Piel, Frédéric Saudou. J Neurosci 2013
8
Brain-derived neurotrophic factor over-expression in the forebrain ameliorates Huntington's disease phenotypes in mice.
Kusumika Gharami, Yuxiang Xie, Juan Ji An, Susumu Tonegawa, Baoji Xu. J Neurochem 2008
Kusumika Gharami, Yuxiang Xie, Juan Ji An, Susumu Tonegawa, Baoji Xu. J Neurochem 2008
8
Differential effects of voluntary physical exercise on behavioral and brain-derived neurotrophic factor expression deficits in Huntington's disease transgenic mice.
T Y C Pang, N C Stam, J Nithianantharajah, M L Howard, A J Hannan. Neuroscience 2006
T Y C Pang, N C Stam, J Nithianantharajah, M L Howard, A J Hannan. Neuroscience 2006
8
Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons.
M DiFiglia, E Sapp, K Chase, C Schwarz, A Meloni, C Young, E Martin, J P Vonsattel, R Carraway, S A Reeves. Neuron 1995
M DiFiglia, E Sapp, K Chase, C Schwarz, A Meloni, C Young, E Martin, J P Vonsattel, R Carraway, S A Reeves. Neuron 1995
8
Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor.
Zachary C Baquet, Jessica A Gorski, Kevin R Jones. J Neurosci 2004
Zachary C Baquet, Jessica A Gorski, Kevin R Jones. J Neurosci 2004
8
Wild-type huntingtin protects neurons from excitotoxicity.
Blair R Leavitt, Jeremy M van Raamsdonk, Jacqueline Shehadeh, Herman Fernandes, Zoe Murphy, Rona K Graham, Cheryl L Wellington, Lynn A Raymond, Michael R Hayden. J Neurochem 2006
Blair R Leavitt, Jeremy M van Raamsdonk, Jacqueline Shehadeh, Herman Fernandes, Zoe Murphy, Rona K Graham, Cheryl L Wellington, Lynn A Raymond, Michael R Hayden. J Neurochem 2006
8
Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice.
Joana M A C Gil, Paul Mohapel, Inês M Araújo, Natalija Popovic, Jia-Yi Li, Patrik Brundin, Asa Petersén. Neurobiol Dis 2005
Joana M A C Gil, Paul Mohapel, Inês M Araújo, Natalija Popovic, Jia-Yi Li, Patrik Brundin, Asa Petersén. Neurobiol Dis 2005
8
Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.
Michelle Gray, Dyna I Shirasaki, Carlos Cepeda, Véronique M André, Brian Wilburn, Xiao-Hong Lu, Jifang Tao, Irene Yamazaki, Shi-Hua Li, Yi E Sun,[...]. J Neurosci 2008
Michelle Gray, Dyna I Shirasaki, Carlos Cepeda, Véronique M André, Brian Wilburn, Xiao-Hong Lu, Jifang Tao, Irene Yamazaki, Shi-Hua Li, Yi E Sun,[...]. J Neurosci 2008
8
Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function.
L A Raymond, V M André, C Cepeda, C M Gladding, A J Milnerwood, M S Levine. Neuroscience 2011
L A Raymond, V M André, C Cepeda, C M Gladding, A J Milnerwood, M S Levine. Neuroscience 2011
8
Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington disease.
Prasad R Joshi, Nan-Ping Wu, Véronique M André, Damian M Cummings, Carlos Cepeda, John A Joyce, Jeffrey B Carroll, Blair R Leavitt, Michael R Hayden, Michael S Levine,[...]. J Neurosci 2009
Prasad R Joshi, Nan-Ping Wu, Véronique M André, Damian M Cummings, Carlos Cepeda, John A Joyce, Jeffrey B Carroll, Blair R Leavitt, Michael R Hayden, Michael S Levine,[...]. J Neurosci 2009
8
Alterations in synaptic function and plasticity in Huntington disease.
Amy I Smith-Dijak, Marja D Sepers, Lynn A Raymond. J Neurochem 2019
Amy I Smith-Dijak, Marja D Sepers, Lynn A Raymond. J Neurochem 2019
17
Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms.
Jennifer Bradford, Ji-Yeon Shin, Meredith Roberts, Chuan-En Wang, Xiao-Jiang Li, Shihua Li. Proc Natl Acad Sci U S A 2009
Jennifer Bradford, Ji-Yeon Shin, Meredith Roberts, Chuan-En Wang, Xiao-Jiang Li, Shihua Li. Proc Natl Acad Sci U S A 2009
8
Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease.
Chiara Zuccato, Nikolai Belyaev, Paola Conforti, Lezanne Ooi, Marzia Tartari, Evangelia Papadimou, Marcy MacDonald, Elisa Fossale, Scott Zeitlin, Noel Buckley,[...]. J Neurosci 2007
Chiara Zuccato, Nikolai Belyaev, Paola Conforti, Lezanne Ooi, Marzia Tartari, Evangelia Papadimou, Marcy MacDonald, Elisa Fossale, Scott Zeitlin, Noel Buckley,[...]. J Neurosci 2007
8
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.
Alexander V Panov, Claire-Anne Gutekunst, Blair R Leavitt, Michael R Hayden, James R Burke, Warren J Strittmatter, J Timothy Greenamyre. Nat Neurosci 2002
Alexander V Panov, Claire-Anne Gutekunst, Blair R Leavitt, Michael R Hayden, James R Burke, Warren J Strittmatter, J Timothy Greenamyre. Nat Neurosci 2002
7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.