G M Pitari, M D Di Guglielmo, J Park, S Schulz, S A Waldman. Proc Natl Acad Sci U S A 2001
Times Cited: 129
Times Cited: 129
Times Cited
Times Co-cited
Similarity
Uroguanylin treatment suppresses polyp formation in the Apc(Min/+) mouse and induces apoptosis in human colon adenocarcinoma cells via cyclic GMP.
K Shailubhai, H H Yu, K Karunanandaa, J Y Wang, S L Eber, Y Wang, N S Joo, H D Kim, B W Miedema, S Z Abbas,[...]. Cancer Res 2000
K Shailubhai, H H Yu, K Karunanandaa, J Y Wang, S L Eber, Y Wang, N S Joo, H D Kim, B W Miedema, S Z Abbas,[...]. Cancer Res 2000
68
Bacterial enterotoxins are associated with resistance to colon cancer.
G M Pitari, L V Zingman, D M Hodgson, A E Alekseev, S Kazerounian, M Bienengraeber, G Hajnóczky, A Terzic, S A Waldman. Proc Natl Acad Sci U S A 2003
G M Pitari, L V Zingman, D M Hodgson, A E Alekseev, S Kazerounian, M Bienengraeber, G Hajnóczky, A Terzic, S A Waldman. Proc Natl Acad Sci U S A 2003
57
Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.
Peng Li, Jieru E Lin, Inna Chervoneva, Stephanie Schulz, Scott A Waldman, Giovanni M Pitari. Am J Pathol 2007
Peng Li, Jieru E Lin, Inna Chervoneva, Stephanie Schulz, Scott A Waldman, Giovanni M Pitari. Am J Pathol 2007
56
Targeted inactivation of the mouse guanylin gene results in altered dynamics of colonic epithelial proliferation.
Kris A Steinbrecher, Steve A Wowk, Jeffrey A Rudolph, David P Witte, Mitchell B Cohen. Am J Pathol 2002
Kris A Steinbrecher, Steve A Wowk, Jeffrey A Rudolph, David P Witte, Mitchell B Cohen. Am J Pathol 2002
55
Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity.
Peng Li, Stephanie Schulz, Alessandro Bombonati, Juan P Palazzo, Terry M Hyslop, Yihuan Xu, Amy A Baran, Linda D Siracusa, Giovanni M Pitari, Scott A Waldman. Gastroenterology 2007
Peng Li, Stephanie Schulz, Alessandro Bombonati, Juan P Palazzo, Terry M Hyslop, Yihuan Xu, Amy A Baran, Linda D Siracusa, Giovanni M Pitari, Scott A Waldman. Gastroenterology 2007
46
Guanylyl cyclases and signaling by cyclic GMP.
K A Lucas, G M Pitari, S Kazerounian, I Ruiz-Stewart, J Park, S Schulz, K P Chepenik, S A Waldman. Pharmacol Rev 2000
K A Lucas, G M Pitari, S Kazerounian, I Ruiz-Stewart, J Park, S Schulz, K P Chepenik, S A Waldman. Pharmacol Rev 2000
42
Expression of guanylin is downregulated in mouse and human intestinal adenomas.
K A Steinbrecher, T M Tuohy, K Heppner Goss, M C Scott, D P Witte, J Groden, M B Cohen. Biochem Biophys Res Commun 2000
K A Steinbrecher, T M Tuohy, K Heppner Goss, M C Scott, D P Witte, J Groden, M B Cohen. Biochem Biophys Res Commun 2000
57
Guanylyl cyclase is a heat-stable enterotoxin receptor.
S Schulz, C K Green, P S Yuen, D L Garbers. Cell 1990
S Schulz, C K Green, P S Yuen, D L Garbers. Cell 1990
37
Uroguanylin: structure and activity of a second endogenous peptide that stimulates intestinal guanylate cyclase.
F K Hamra, L R Forte, S L Eber, N V Pidhorodeckyj, W J Krause, R H Freeman, D T Chin, J A Tompkins, K F Fok, C E Smith. Proc Natl Acad Sci U S A 1993
F K Hamra, L R Forte, S L Eber, N V Pidhorodeckyj, W J Krause, R H Freeman, D T Chin, J A Tompkins, K F Fok, C E Smith. Proc Natl Acad Sci U S A 1993
35
Guanylyl cyclase C is a selective marker for metastatic colorectal tumors in human extraintestinal tissues.
S L Carrithers, M T Barber, S Biswas, S J Parkinson, P K Park, S D Goldstein, S A Waldman. Proc Natl Acad Sci U S A 1996
S L Carrithers, M T Barber, S Biswas, S J Parkinson, P K Park, S D Goldstein, S A Waldman. Proc Natl Acad Sci U S A 1996
35
The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling.
Jieru Egeria Lin, Peng Li, Adam Eugene Snook, Stephanie Schulz, Abhijit Dasgupta, Terry Marie Hyslop, Ahmara Vivian Gibbons, Glen Marszlowicz, Giovanni Mario Pitari, Scott Arthur Waldman. Gastroenterology 2010
Jieru Egeria Lin, Peng Li, Adam Eugene Snook, Stephanie Schulz, Abhijit Dasgupta, Terry Marie Hyslop, Ahmara Vivian Gibbons, Glen Marszlowicz, Giovanni Mario Pitari, Scott Arthur Waldman. Gastroenterology 2010
40
Guanylyl cyclase C is a marker of intestinal metaplasia, dysplasia, and adenocarcinoma of the gastrointestinal tract.
Ruth Birbe, Juan P Palazzo, Rhonda Walters, David Weinberg, Stephanie Schulz, Scott A Waldman. Hum Pathol 2005
Ruth Birbe, Juan P Palazzo, Rhonda Walters, David Weinberg, Stephanie Schulz, Scott A Waldman. Hum Pathol 2005
32
Transcriptional gene expression profiles of colorectal adenoma, adenocarcinoma, and normal tissue examined by oligonucleotide arrays.
D A Notterman, U Alon, A J Sierk, A J Levine. Cancer Res 2001
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30
Guanylin: an endogenous activator of intestinal guanylate cyclase.
M G Currie, K F Fok, J Kato, R J Moore, F K Hamra, K L Duffin, C E Smith. Proc Natl Acad Sci U S A 1992
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29
Disruption of the guanylyl cyclase-C gene leads to a paradoxical phenotype of viable but heat-stable enterotoxin-resistant mice.
S Schulz, M J Lopez, M Kuhn, D L Garbers. J Clin Invest 1997
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29
Interruption of homologous desensitization in cyclic guanosine 3',5'-monophosphate signaling restores colon cancer cytostasis by bacterial enterotoxins.
Giovanni M Pitari, Ronnie I Baksh, David M Harris, Peng Li, Shiva Kazerounian, Scott A Waldman. Cancer Res 2005
Giovanni M Pitari, Ronnie I Baksh, David M Harris, Peng Li, Shiva Kazerounian, Scott A Waldman. Cancer Res 2005
90
Guanylin mRNA expression in human intestine and colorectal adenocarcinoma.
M B Cohen, J A Hawkins, D P Witte. Lab Invest 1998
M B Cohen, J A Hawkins, D P Witte. Lab Invest 1998
35
Exisulind induction of apoptosis involves guanosine 3',5'-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin.
W J Thompson, G A Piazza, H Li, L Liu, J Fetter, B Zhu, G Sperl, D Ahnen, R Pamukcu. Cancer Res 2000
W J Thompson, G A Piazza, H Li, L Liu, J Fetter, B Zhu, G Sperl, D Ahnen, R Pamukcu. Cancer Res 2000
22
A validated quantitative assay to detect occult micrometastases by reverse transcriptase-polymerase chain reaction of guanylyl cyclase C in patients with colorectal cancer.
Stephanie Schulz, Terry Hyslop, Janis Haaf, Christine Bonaccorso, Karl Nielsen, Matthew E Witek, Ruth Birbe, Juan Palazzo, David Weinberg, Scott A Waldman. Clin Cancer Res 2006
Stephanie Schulz, Terry Hyslop, Janis Haaf, Christine Bonaccorso, Karl Nielsen, Matthew E Witek, Ruth Birbe, Juan Palazzo, David Weinberg, Scott A Waldman. Clin Cancer Res 2006
34
Escherichia coli heat-stable toxin receptors in human colonic tumors.
S L Carrithers, S J Parkinson, S Goldstein, P Park, D C Robertson, S A Waldman. Gastroenterology 1994
S L Carrithers, S J Parkinson, S Goldstein, P Park, D C Robertson, S A Waldman. Gastroenterology 1994
26
The paracrine hormone hypothesis of colorectal cancer.
G M Pitari, P Li, J E Lin, D Zuzga, A V Gibbons, A E Snook, S Schulz, S A Waldman. Clin Pharmacol Ther 2007
G M Pitari, P Li, J E Lin, D Zuzga, A V Gibbons, A E Snook, S Schulz, S A Waldman. Clin Pharmacol Ther 2007
45
Guanylyl cyclase C messenger RNA is a biomarker for recurrent stage II colorectal cancer.
B Cagir, A Gelmann, J Park, T Fava, A Tankelevitch, E W Bittner, E J Weaver, J P Palazzo, D Weinberg, R D Fry,[...]. Ann Intern Med 1999
B Cagir, A Gelmann, J Park, T Fava, A Tankelevitch, E W Bittner, E J Weaver, J P Palazzo, D Weinberg, R D Fry,[...]. Ann Intern Med 1999
19
Guanylin and uroguanylin induce natriuresis in mice lacking guanylyl cyclase-C receptor.
Stephen L Carrithers, Cobern E Ott, Michael J Hill, Brett R Johnson, Weiyan Cai, Jason J Chang, Rajesh G Shah, Congmei Sun, Elizabeth A Mann, Manasses C Fonteles,[...]. Kidney Int 2004
Stephen L Carrithers, Cobern E Ott, Michael J Hill, Brett R Johnson, Weiyan Cai, Jason J Chang, Rajesh G Shah, Congmei Sun, Elizabeth A Mann, Manasses C Fonteles,[...]. Kidney Int 2004
25
Heat-stable enterotoxin of Escherichia coli: in vitro effects on guanylate cyclase activity, cyclic GMP concentration, and ion transport in small intestine.
M Field, L H Graf, W J Laird, P L Smith. Proc Natl Acad Sci U S A 1978
M Field, L H Graf, W J Laird, P L Smith. Proc Natl Acad Sci U S A 1978
18
Association of GUCY2C expression in lymph nodes with time to recurrence and disease-free survival in pN0 colorectal cancer.
Scott A Waldman, Terry Hyslop, Stephanie Schulz, Alan Barkun, Karl Nielsen, Janis Haaf, Christine Bonaccorso, Yanyan Li, David S Weinberg. JAMA 2009
Scott A Waldman, Terry Hyslop, Stephanie Schulz, Alan Barkun, Karl Nielsen, Janis Haaf, Christine Bonaccorso, Yanyan Li, David S Weinberg. JAMA 2009
21
Mice lacking the guanylyl cyclase C receptor are resistant to STa-induced intestinal secretion.
E A Mann, M L Jump, J Wu, E Yee, R A Giannella. Biochem Biophys Res Commun 1997
E A Mann, M L Jump, J Wu, E Yee, R A Giannella. Biochem Biophys Res Commun 1997
17
Uroguanylin and guanylin peptides: pharmacology and experimental therapeutics.
Leonard Ralph Forte. Pharmacol Ther 2004
Leonard Ralph Forte. Pharmacol Ther 2004
17
Gene expression in colorectal cancer.
Karin Birkenkamp-Demtroder, Lise Lotte Christensen, Sanne Harder Olesen, Casper M Frederiksen, Päivi Laiho, Lauri A Aaltonen, Søren Laurberg, Flemming B Sørensen, Rikke Hagemann, Torben F ØRntoft. Cancer Res 2002
Karin Birkenkamp-Demtroder, Lise Lotte Christensen, Sanne Harder Olesen, Casper M Frederiksen, Päivi Laiho, Lauri A Aaltonen, Søren Laurberg, Flemming B Sørensen, Rikke Hagemann, Torben F ØRntoft. Cancer Res 2002
17
Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells.
Atsuko Deguchi, W Joseph Thompson, I Bernard Weinstein. Cancer Res 2004
Atsuko Deguchi, W Joseph Thompson, I Bernard Weinstein. Cancer Res 2004
17
Gene expression profiles in normal and cancer cells.
L Zhang, W Zhou, V E Velculescu, S E Kern, R H Hruban, S R Hamilton, B Vogelstein, K W Kinzler. Science 1997
L Zhang, W Zhou, V E Velculescu, S E Kern, R H Hruban, S R Hamilton, B Vogelstein, K W Kinzler. Science 1997
16
Loss of guanylyl cyclase C (GCC) signaling leads to dysfunctional intestinal barrier.
Xiaonan Han, Elizabeth Mann, Shila Gilbert, Yanfang Guan, Kris A Steinbrecher, Marshall H Montrose, Mitchell B Cohen. PLoS One 2011
Xiaonan Han, Elizabeth Mann, Shila Gilbert, Yanfang Guan, Kris A Steinbrecher, Marshall H Montrose, Mitchell B Cohen. PLoS One 2011
25
Meconium ileus caused by mutations in GUCY2C, encoding the CFTR-activating guanylate cyclase 2C.
Hila Romi, Idan Cohen, Daniella Landau, Suliman Alkrinawi, Baruch Yerushalmi, Reli Hershkovitz, Nitza Newman-Heiman, Garry R Cutting, Rivka Ofir, Sara Sivan,[...]. Am J Hum Genet 2012
Hila Romi, Idan Cohen, Daniella Landau, Suliman Alkrinawi, Baruch Yerushalmi, Reli Hershkovitz, Nitza Newman-Heiman, Garry R Cutting, Rivka Ofir, Sara Sivan,[...]. Am J Hum Genet 2012
27
Familial diarrhea syndrome caused by an activating GUCY2C mutation.
Torunn Fiskerstrand, Najla Arshad, Bjørn Ivar Haukanes, Rune Rose Tronstad, Khanh Do-Cong Pham, Stefan Johansson, Bjarte Håvik, Siv L Tønder, Shawn E Levy, Damien Brackman,[...]. N Engl J Med 2012
Torunn Fiskerstrand, Najla Arshad, Bjørn Ivar Haukanes, Rune Rose Tronstad, Khanh Do-Cong Pham, Stefan Johansson, Bjarte Håvik, Siv L Tønder, Shawn E Levy, Damien Brackman,[...]. N Engl J Med 2012
16
Cyclic GMP-dependent protein kinase activation and induction by exisulind and CP461 in colon tumor cells.
L Liu, H Li, T Underwood, M Lloyd, M David, G Sperl, R Pamukcu, W J Thompson. J Pharmacol Exp Ther 2001
L Liu, H Li, T Underwood, M Lloyd, M David, G Sperl, R Pamukcu, W J Thompson. J Pharmacol Exp Ther 2001
19
GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity.
Jieru Egeria Lin, Adam Eugene Snook, Peng Li, Brian Arthur Stoecker, Gilbert Won Kim, Michael Sullivan Magee, Alex Vladimir Mejia Garcia, Michael Anthony Valentino, Terry Hyslop, Stephanie Schulz,[...]. PLoS One 2012
Jieru Egeria Lin, Adam Eugene Snook, Peng Li, Brian Arthur Stoecker, Gilbert Won Kim, Michael Sullivan Magee, Alex Vladimir Mejia Garcia, Michael Anthony Valentino, Terry Hyslop, Stephanie Schulz,[...]. PLoS One 2012
24
The paracrine hormone for the GUCY2C tumor suppressor, guanylin, is universally lost in colorectal cancer.
Chantell Wilson, Jieru E Lin, Peng Li, Adam E Snook, Jianping Gong, Takahiro Sato, Chengbao Liu, Melanie A Girondo, Hallgeir Rui, Terry Hyslop,[...]. Cancer Epidemiol Biomarkers Prev 2014
Chantell Wilson, Jieru E Lin, Peng Li, Adam E Snook, Jianping Gong, Takahiro Sato, Chengbao Liu, Melanie A Girondo, Hallgeir Rui, Terry Hyslop,[...]. Cancer Epidemiol Biomarkers Prev 2014
38
Regulation of intestinal uroguanylin/guanylin receptor-mediated responses by mucosal acidity.
F K Hamra, S L Eber, D T Chin, M G Currie, L R Forte. Proc Natl Acad Sci U S A 1997
F K Hamra, S L Eber, D T Chin, M G Currie, L R Forte. Proc Natl Acad Sci U S A 1997
14
Colorectal cancer is a paracrine deficiency syndrome amenable to oral hormone replacement therapy.
P Li, J E Lin, A E Snook, A V Gibbons, D S Zuzga, S Schulz, G M Pitari, S A Waldman. Clin Transl Sci 2008
P Li, J E Lin, A E Snook, A V Gibbons, D S Zuzga, S Schulz, G M Pitari, S A Waldman. Clin Transl Sci 2008
70
In vivo imaging of human colon cancer xenografts in immunodeficient mice using a guanylyl cyclase C--specific ligand.
Henry R Wolfe, Marivi Mendizabal, Elinor Lleong, Alan Cuthbertson, Vinay Desai, Shirley Pullan, Dennis K Fujii, Matthew Morrison, Richard Pither, Scott A Waldman. J Nucl Med 2002
Henry R Wolfe, Marivi Mendizabal, Elinor Lleong, Alan Cuthbertson, Vinay Desai, Shirley Pullan, Dennis K Fujii, Matthew Morrison, Richard Pither, Scott A Waldman. J Nucl Med 2002
29
The putative tumor suppressor Cdx2 is overexpressed by human colorectal adenocarcinomas.
Matthew E Witek, Karl Nielsen, Rhonda Walters, Terry Hyslop, Juan Palazzo, Stephanie Schulz, Scott A Waldman. Clin Cancer Res 2005
Matthew E Witek, Karl Nielsen, Rhonda Walters, Terry Hyslop, Juan Palazzo, Stephanie Schulz, Scott A Waldman. Clin Cancer Res 2005
18
A uroguanylin-GUCY2C endocrine axis regulates feeding in mice.
Michael A Valentino, Jieru E Lin, Adam E Snook, Peng Li, Gilbert W Kim, Glen Marszalowicz, Michael S Magee, Terry Hyslop, Stephanie Schulz, Scott A Waldman. J Clin Invest 2011
Michael A Valentino, Jieru E Lin, Adam E Snook, Peng Li, Gilbert W Kim, Glen Marszalowicz, Michael S Magee, Terry Hyslop, Stephanie Schulz, Scott A Waldman. J Clin Invest 2011
13
Differential role of cyclic GMP-dependent protein kinase II in ion transport in murine small intestine and colon.
A B Vaandrager, A G Bot, P Ruth, A Pfeifer, F Hofmann, H R De Jonge. Gastroenterology 2000
A B Vaandrager, A G Bot, P Ruth, A Pfeifer, F Hofmann, H R De Jonge. Gastroenterology 2000
12
Heterogeneity of guanylyl cyclase C expressed by human colorectal cancer cell lines in vitro.
S A Waldman, M Barber, J Pearlman, J Park, R George, S J Parkinson. Cancer Epidemiol Biomarkers Prev 1998
S A Waldman, M Barber, J Pearlman, J Park, R George, S J Parkinson. Cancer Epidemiol Biomarkers Prev 1998
31
Use of guanylyl cyclase C for detecting micrometastases in lymph nodes of patients with colon cancer.
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15
Role of cyclic GMP in the action of heat-stable enterotoxin of Escherichia coli.
J M Hughes, F Murad, B Chang, R L Guerrant. Nature 1978
J M Hughes, F Murad, B Chang, R L Guerrant. Nature 1978
12
Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis.
Jieru E Lin, Francheska Colon-Gonzalez, Erik Blomain, Gilbert W Kim, Amanda Aing, Brian Stoecker, Justin Rock, Adam E Snook, Tingting Zhan, Terry M Hyslop,[...]. Cancer Res 2016
Jieru E Lin, Francheska Colon-Gonzalez, Erik Blomain, Gilbert W Kim, Amanda Aing, Brian Stoecker, Justin Rock, Adam E Snook, Tingting Zhan, Terry M Hyslop,[...]. Cancer Res 2016
30
Activation of intestinal CFTR Cl- channel by heat-stable enterotoxin and guanylin via cAMP-dependent protein kinase.
A C Chao, F J de Sauvage, Y J Dong, J A Wagner, D V Goeddel, P Gardner. EMBO J 1994
A C Chao, F J de Sauvage, Y J Dong, J A Wagner, D V Goeddel, P Gardner. EMBO J 1994
11
Activation of intestinal guanylate cyclase by heat-stable enterotoxin of Escherichia coli: studies of tissue specificity, potential receptors, and intermediates.
R L Guerrant, J M Hughes, B Chang, D C Robertson, F Murad. J Infect Dis 1980
R L Guerrant, J M Hughes, B Chang, D C Robertson, F Murad. J Infect Dis 1980
11
Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target.
Jieru E Lin, Peng Li, Giovanni M Pitari, Stephanie Schulz, Scott A Waldman. Future Oncol 2009
Jieru E Lin, Peng Li, Giovanni M Pitari, Stephanie Schulz, Scott A Waldman. Future Oncol 2009
55
Enterotoxin preconditioning restores calcium-sensing receptor-mediated cytostasis in colon cancer cells.
Giovanni M Pitari, Jieru E Lin, Fawad J Shah, Wilhelm J Lubbe, David S Zuzga, Peng Li, Stephanie Schulz, Scott A Waldman. Carcinogenesis 2008
Giovanni M Pitari, Jieru E Lin, Fawad J Shah, Wilhelm J Lubbe, David S Zuzga, Peng Li, Stephanie Schulz, Scott A Waldman. Carcinogenesis 2008
52
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.