A citation-based method for searching scientific literature

H Ariyasu, K Takaya, T Tagami, Y Ogawa, K Hosoda, T Akamizu, M Suda, T Koh, K Natsui, S Toyooka, G Shirakami, T Usui, A Shimatsu, K Doi, H Hosoda, M Kojima, K Kangawa, K Nakao. J Clin Endocrinol Metab 2001
Times Cited: 917







List of co-cited articles
1229 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Ghrelin is a growth-hormone-releasing acylated peptide from stomach.
M Kojima, H Hosoda, Y Date, M Nakazato, H Matsuo, K Kangawa. Nature 1999
59

A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans.
D E Cummings, J Q Purnell, R S Frayo, K Schmidova, B E Wisse, D S Weigle. Diabetes 2001
37

Ghrelin induces adiposity in rodents.
M Tschöp, D L Smiley, M L Heiman. Nature 2000
33

Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone.
Jing Yang, Michael S Brown, Guosheng Liang, Nick V Grishin, Joseph L Goldstein. Cell 2008
791
29

Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans.
Y Date, M Kojima, H Hosoda, A Sawaguchi, M S Mondal, T Suganuma, S Matsukura, K Kangawa, M Nakazato. Endocrinology 2000
27

A role for ghrelin in the central regulation of feeding.
M Nakazato, N Murakami, Y Date, M Kojima, H Matsuo, K Kangawa, S Matsukura. Nature 2001
25

Ghrelin octanoylation mediated by an orphan lipid transferase.
Jesus A Gutierrez, Patricia J Solenberg, Douglas R Perkins, Jill A Willency, Michael D Knierman, Zhaoyan Jin, Derrick R Witcher, Shuang Luo, Jude E Onyia, John E Hale. Proc Natl Acad Sci U S A 2008
584
23

A receptor in pituitary and hypothalamus that functions in growth hormone release.
A D Howard, S D Feighner, D F Cully, J P Arena, P A Liberator, C I Rosenblum, M Hamelin, D L Hreniuk, O C Palyha, J Anderson,[...]. Science 1996
20

Ghrelin.
T D Müller, R Nogueiras, M L Andermann, Z B Andrews, S D Anker, J Argente, R L Batterham, S C Benoit, C Y Bowers, F Broglio,[...]. Mol Metab 2015
480
20

Ghrelin enhances appetite and increases food intake in humans.
A M Wren, L J Seal, M A Cohen, A E Brynes, G S Frost, K G Murphy, W S Dhillo, M A Ghatei, S R Bloom. J Clin Endocrinol Metab 2001
19

Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues.
X M Guan, H Yu, O C Palyha, K K McKee, S D Feighner, D J Sirinathsinghji, R G Smith, L H Van der Ploeg, A D Howard. Brain Res Mol Brain Res 1997
835
19

Ghrelin causes hyperphagia and obesity in rats.
A M Wren, C J Small, C R Abbott, W S Dhillo, L J Seal, M A Cohen, R L Batterham, S Taheri, S A Stanley, M A Ghatei,[...]. Diabetes 2001
852
19

Expression of ghrelin receptor mRNA in the rat and the mouse brain.
Jeffrey M Zigman, Juli E Jones, Charlotte E Lee, Clifford B Saper, Joel K Elmquist. J Comp Neurol 2006
689
19

The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans.
Sharmilee Gnanapavan, Blerina Kola, Stephen A Bustin, Damian G Morris, Patrick McGee, Peter Fairclough, Satya Bhattacharya, Robert Carpenter, Ashley B Grossman, Márta Korbonits. J Clin Endocrinol Metab 2002
18

The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis.
Michael A Cowley, Roy G Smith, Sabrina Diano, Matthias Tschöp, Nina Pronchuk, Kevin L Grove, Christian J Strasburger, Martin Bidlingmaier, Michael Esterman, Mark L Heiman,[...]. Neuron 2003
17

Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice.
Tong-Jin Zhao, Guosheng Liang, Robert Lin Li, Xuefen Xie, Mark W Sleeman, Andrew J Murphy, David M Valenzuela, George D Yancopoulos, Joseph L Goldstein, Michael S Brown. Proc Natl Acad Sci U S A 2010
305
17

Ghrelin mediates stress-induced food-reward behavior in mice.
Jen-Chieh Chuang, Mario Perello, Ichiro Sakata, Sherri Osborne-Lawrence, Joseph M Savitt, Michael Lutter, Jeffrey M Zigman. J Clin Invest 2011
201
16


Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery.
David E Cummings, David S Weigle, R Scott Frayo, Patricia A Breen, Marina K Ma, E Patchen Dellinger, Jonathan Q Purnell. N Engl J Med 2002
14

Mice lacking ghrelin receptors resist the development of diet-induced obesity.
Jeffrey M Zigman, Yoshihide Nakano, Roberto Coppari, Nina Balthasar, Jacob N Marcus, Charlotte E Lee, Juli E Jones, Amy E Deysher, Amanda R Waxman, Ryan D White,[...]. J Clin Invest 2005
441
14

Deletion of ghrelin impairs neither growth nor appetite.
Yuxiang Sun, Saira Ahmed, Roy G Smith. Mol Cell Biol 2003
475
14

Circulating ghrelin levels are decreased in human obesity.
M Tschöp, C Weyer, P A Tataranni, V Devanarayan, E Ravussin, M L Heiman. Diabetes 2001
14

LEAP2 Is an Endogenous Antagonist of the Ghrelin Receptor.
Xuecai Ge, Hong Yang, Maria A Bednarek, Hadas Galon-Tilleman, Peirong Chen, Michael Chen, Joshua S Lichtman, Yan Wang, Olivier Dalmas, Yiyuan Yin,[...]. Cell Metab 2018
84
16

Induced ablation of ghrelin cells in adult mice does not decrease food intake, body weight, or response to high-fat diet.
Matthew R McFarlane, Michael S Brown, Joseph L Goldstein, Tong-Jin Zhao. Cell Metab 2014
104
13

Ghrelin: structure and function.
Masayasu Kojima, Kenji Kangawa. Physiol Rev 2005
13

Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion.
Tomomi Shiiya, Masamitsu Nakazato, Masanari Mizuta, Yukari Date, Muhtashan S Mondal, Muneki Tanaka, Shin-Ichi Nozoe, Hiroshi Hosoda, Kenji Kangawa, Shigeru Matsukura. J Clin Endocrinol Metab 2002
957
13

The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats.
Yukari Date, Noboru Murakami, Koji Toshinai, Shigeru Matsukura, Akira Niijima, Hisayuki Matsuo, Kenji Kangawa, Masamitsu Nakazato. Gastroenterology 2002
793
12

Des-Acyl Ghrelin Directly Targets the Arcuate Nucleus in a Ghrelin-Receptor Independent Manner and Impairs the Orexigenic Effect of Ghrelin.
G Fernandez, A Cabral, M P Cornejo, P N De Francesco, G Garcia-Romero, M Reynaldo, M Perello. J Neuroendocrinol 2016
54
22

Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure.
William A Banks, Matthias Tschöp, Sandra M Robinson, Mark L Heiman. J Pharmacol Exp Ther 2002
486
12

Ghrelin increases the rewarding value of high-fat diet in an orexin-dependent manner.
Mario Perello, Ichiro Sakata, Shari Birnbaum, Jen-Chieh Chuang, Sherri Osborne-Lawrence, Sherry A Rovinsky, Jakub Woloszyn, Masashi Yanagisawa, Michael Lutter, Jeffrey M Zigman. Biol Psychiatry 2010
251
12

Genetic deletion of ghrelin does not decrease food intake but influences metabolic fuel preference.
Katherine E Wortley, Keith D Anderson, Karen Garcia, Jane D Murray, Lubomira Malinova, Rong Liu, Marshena Moncrieffe, Karen Thabet, Hilary J Cox, George D Yancopoulos,[...]. Proc Natl Acad Sci U S A 2004
338
12

Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue.
H Hosoda, M Kojima, H Matsuo, K Kangawa. Biochem Biophys Res Commun 2000
703
12

GOAT links dietary lipids with the endocrine control of energy balance.
Henriette Kirchner, Jesus A Gutierrez, Patricia J Solenberg, Paul T Pfluger, Traci A Czyzyk, Jill A Willency, Annette Schürmann, Hans-Georg Joost, Ronald J Jandacek, John E Hale,[...]. Nat Med 2009
297
12

Post-prandial decrease of circulating human ghrelin levels.
M Tschöp, R Wawarta, R L Riepl, S Friedrich, M Bidlingmaier, R Landgraf, C Folwaczny. J Endocrinol Invest 2001
488
12

Ghrelin stimulates gastric acid secretion and motility in rats.
Y Masuda, T Tanaka, N Inomata, N Ohnuma, S Tanaka, Z Itoh, H Hosoda, M Kojima, K Kangawa. Biochem Biophys Res Commun 2000
667
11

Desacyl ghrelin inhibits the orexigenic effect of peripherally injected ghrelin in rats.
Tobias Inhoff, Hubert Mönnikes, Steffen Noetzel, Andreas Stengel, Miriam Goebel, Q Thai Dinh, Andrea Riedl, Norbert Bannert, Anna-Sophia Wisser, Bertram Wiedenmann,[...]. Peptides 2008
140
11

Hyperphagic effects of brainstem ghrelin administration.
Lucy F Faulconbridge, David E Cummings, Joel M Kaplan, Harvey J Grill. Diabetes 2003
205
11

Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin.
A Asakawa, A Inui, T Kaga, H Yuzuriha, T Nagata, N Ueno, S Makino, M Fujimiya, A Niijima, M A Fujino,[...]. Gastroenterology 2001
895
11

Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans.
F Broglio, E Arvat, A Benso, C Gottero, G Muccioli, M Papotti, A J van der Lely, R Deghenghi, E Ghigo. J Clin Endocrinol Metab 2001
529
11

Ghrelin is present in pancreatic alpha-cells of humans and rats and stimulates insulin secretion.
Yukari Date, Masamitsu Nakazato, Suzuko Hashiguchi, Katsuya Dezaki, Muhtashan S Mondal, Hiroshi Hosoda, Masayasu Kojima, Kenji Kangawa, Terukatsu Arima, Hisayuki Matsuo,[...]. Diabetes 2002
447
11

Arcuate AgRP neurons mediate orexigenic and glucoregulatory actions of ghrelin.
Qian Wang, Chen Liu, Aki Uchida, Jen-Chieh Chuang, Angela Walker, Tiemin Liu, Sherri Osborne-Lawrence, Brittany L Mason, Christina Mosher, Eric D Berglund,[...]. Mol Metab 2013
144
11

Ghrelin secretion stimulated by {beta}1-adrenergic receptors in cultured ghrelinoma cells and in fasted mice.
Tong-Jin Zhao, Ichiro Sakata, Robert Lin Li, Guosheng Liang, James A Richardson, Michael S Brown, Joseph L Goldstein, Jeffrey M Zigman. Proc Natl Acad Sci U S A 2010
139
11

Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor.
Brad P Barnett, Yousang Hwang, Martin S Taylor, Henriette Kirchner, Paul T Pfluger, Vincent Bernard, Yu-yi Lin, Erin M Bowers, Chandrani Mukherjee, Woo-Jin Song,[...]. Science 2010
192
10

Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite.
Alfonso Abizaid, Zhong-Wu Liu, Zane B Andrews, Marya Shanabrough, Erzsebet Borok, John D Elsworth, Robert H Roth, Mark W Sleeman, Marina R Picciotto, Matthias H Tschöp,[...]. J Clin Invest 2006
645
10

Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake.
Jian V Zhang, Pei-Gen Ren, Orna Avsian-Kretchmer, Ching-Wei Luo, Rami Rauch, Cynthia Klein, Aaron J W Hsueh. Science 2005
808
10


β1-Adrenergic receptor deficiency in ghrelin-expressing cells causes hypoglycemia in susceptible individuals.
Bharath K Mani, Sherri Osborne-Lawrence, Prasanna Vijayaraghavan, Chelsea Hepler, Jeffrey M Zigman. J Clin Invest 2016
31
32

Ghrelin directly stimulates glucagon secretion from pancreatic alpha-cells.
Jen-Chieh Chuang, Ichiro Sakata, Daisuke Kohno, Mario Perello, Sherri Osborne-Lawrence, Joyce J Repa, Jeffrey M Zigman. Mol Endocrinol 2011
87
11

Ghrelin increases food intake in obese as well as lean subjects.
M R Druce, A M Wren, A J Park, J E Milton, M Patterson, G Frost, M A Ghatei, C Small, S R Bloom. Int J Obes (Lond) 2005
255
10

Ghrelin-producing cells exist as two types of cells, closed- and opened-type cells, in the rat gastrointestinal tract.
Ichiro Sakata, Kazuaki Nakamura, Mami Yamazaki, Maki Matsubara, Yuijiro Hayashi, Kenji Kangawa, Takafumi Sakai. Peptides 2002
231
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.