J C Darnell, K B Jensen, P Jin, V Brown, S T Warren, R B Darnell. Cell 2001
Times Cited: 728
Times Cited: 728
Times Cited
Times Co-cited
Similarity
FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism.
Jennifer C Darnell, Sarah J Van Driesche, Chaolin Zhang, Ka Ying Sharon Hung, Aldo Mele, Claire E Fraser, Elizabeth F Stone, Cynthia Chen, John J Fak, Sung Wook Chi,[...]. Cell 2011
Jennifer C Darnell, Sarah J Van Driesche, Chaolin Zhang, Ka Ying Sharon Hung, Aldo Mele, Claire E Fraser, Elizabeth F Stone, Cynthia Chen, John J Fak, Sung Wook Chi,[...]. Cell 2011
55
Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome.
V Brown, P Jin, S Ceman, J C Darnell, W T O'Donnell, S A Tenenbaum, X Jin, Y Feng, K D Wilkinson, J D Keene,[...]. Cell 2001
V Brown, P Jin, S Ceman, J C Darnell, W T O'Donnell, S A Tenenbaum, X Jin, Y Feng, K D Wilkinson, J D Keene,[...]. Cell 2001
35
FMRP targets distinct mRNA sequence elements to regulate protein expression.
Manuel Ascano, Neelanjan Mukherjee, Pradeep Bandaru, Jason B Miller, Jeffrey D Nusbaum, David L Corcoran, Christine Langlois, Mathias Munschauer, Scott Dewell, Markus Hafner,[...]. Nature 2012
Manuel Ascano, Neelanjan Mukherjee, Pradeep Bandaru, Jason B Miller, Jeffrey D Nusbaum, David L Corcoran, Christine Langlois, Mathias Munschauer, Scott Dewell, Markus Hafner,[...]. Nature 2012
33
Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome.
A J Verkerk, M Pieretti, J S Sutcliffe, Y H Fu, D P Kuhl, A Pizzuti, O Reiner, S Richards, M F Victoria, F P Zhang. Cell 1991
A J Verkerk, M Pieretti, J S Sutcliffe, Y H Fu, D P Kuhl, A Pizzuti, O Reiner, S Richards, M F Victoria, F P Zhang. Cell 1991
28
The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif.
C Schaeffer, B Bardoni, J L Mandel, B Ehresmann, C Ehresmann, H Moine. EMBO J 2001
C Schaeffer, B Bardoni, J L Mandel, B Ehresmann, C Ehresmann, H Moine. EMBO J 2001
26
Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes.
Jennifer C Darnell, Claire E Fraser, Olga Mostovetsky, Giovanni Stefani, Thomas A Jones, Sean R Eddy, Robert B Darnell. Genes Dev 2005
Jennifer C Darnell, Claire E Fraser, Olga Mostovetsky, Giovanni Stefani, Thomas A Jones, Sean R Eddy, Robert B Darnell. Genes Dev 2005
24
Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signaling.
Ravi S Muddashetty, Vijayalaxmi C Nalavadi, Christina Gross, Xiaodi Yao, Lei Xing, Oskar Laur, Stephen T Warren, Gary J Bassell. Mol Cell 2011
Ravi S Muddashetty, Vijayalaxmi C Nalavadi, Christina Gross, Xiaodi Yao, Lei Xing, Oskar Laur, Stephen T Warren, Gary J Bassell. Mol Cell 2011
23
The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP.
Ilaria Napoli, Valentina Mercaldo, Pietro Pilo Boyl, Boris Eleuteri, Francesca Zalfa, Silvia De Rubeis, Daniele Di Marino, Evita Mohr, Marzia Massimi, Mattia Falconi,[...]. Cell 2008
Ilaria Napoli, Valentina Mercaldo, Pietro Pilo Boyl, Boris Eleuteri, Francesca Zalfa, Silvia De Rubeis, Daniele Di Marino, Evita Mohr, Marzia Massimi, Mattia Falconi,[...]. Cell 2008
22
Altered synaptic plasticity in a mouse model of fragile X mental retardation.
Kimberly M Huber, Sean M Gallagher, Stephen T Warren, Mark F Bear. Proc Natl Acad Sci U S A 2002
Kimberly M Huber, Sean M Gallagher, Stephen T Warren, Mark F Bear. Proc Natl Acad Sci U S A 2002
21
Molecular mechanisms of fragile X syndrome: a twenty-year perspective.
Michael R Santoro, Steven M Bray, Stephen T Warren. Annu Rev Pathol 2012
Michael R Santoro, Steven M Bray, Stephen T Warren. Annu Rev Pathol 2012
19
Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP.
Nikita Vasilyev, Anna Polonskaia, Jennifer C Darnell, Robert B Darnell, Dinshaw J Patel, Alexander Serganov. Proc Natl Acad Sci U S A 2015
Nikita Vasilyev, Anna Polonskaia, Jennifer C Darnell, Robert B Darnell, Dinshaw J Patel, Alexander Serganov. Proc Natl Acad Sci U S A 2015
18
A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome.
Jason B Dictenberg, Sharon A Swanger, Laura N Antar, Robert H Singer, Gary J Bassell. Dev Cell 2008
Jason B Dictenberg, Sharon A Swanger, Laura N Antar, Robert H Singer, Gary J Bassell. Dev Cell 2008
18
Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function.
Gary J Bassell, Stephen T Warren. Neuron 2008
Gary J Bassell, Stephen T Warren. Neuron 2008
17
The mGluR theory of fragile X mental retardation.
Mark F Bear, Kimberly M Huber, Stephen T Warren. Trends Neurosci 2004
Mark F Bear, Kimberly M Huber, Stephen T Warren. Trends Neurosci 2004
17
The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein.
H Siomi, M C Siomi, R L Nussbaum, G Dreyfuss. Cell 1993
H Siomi, M C Siomi, R L Nussbaum, G Dreyfuss. Cell 1993
17
Fragile X syndrome.
Randi J Hagerman, Elizabeth Berry-Kravis, Heather Cody Hazlett, Donald B Bailey, Herve Moine, R Frank Kooy, Flora Tassone, Ilse Gantois, Nahum Sonenberg, Jean Louis Mandel,[...]. Nat Rev Dis Primers 2017
Randi J Hagerman, Elizabeth Berry-Kravis, Heather Cody Hazlett, Donald B Bailey, Herve Moine, R Frank Kooy, Flora Tassone, Ilse Gantois, Nahum Sonenberg, Jean Louis Mandel,[...]. Nat Rev Dis Primers 2017
17
The translation of translational control by FMRP: therapeutic targets for FXS.
Jennifer C Darnell, Eric Klann. Nat Neurosci 2013
Jennifer C Darnell, Eric Klann. Nat Neurosci 2013
17
Fragile X mental retardation protein regulates translation by binding directly to the ribosome.
Eileen Chen, Manjuli R Sharma, Xinying Shi, Rajendra K Agrawal, Simpson Joseph. Mol Cell 2014
Eileen Chen, Manjuli R Sharma, Xinying Shi, Rajendra K Agrawal, Simpson Joseph. Mol Cell 2014
16
Dysregulation and restoration of translational homeostasis in fragile X syndrome.
Joel D Richter, Gary J Bassell, Eric Klann. Nat Rev Neurosci 2015
Joel D Richter, Gary J Bassell, Eric Klann. Nat Rev Neurosci 2015
16
Phosphorylation influences the translation state of FMRP-associated polyribosomes.
Stephanie Ceman, William T O'Donnell, Matt Reed, Stephana Patton, Jan Pohl, Stephen T Warren. Hum Mol Genet 2003
Stephanie Ceman, William T O'Donnell, Matt Reed, Stephana Patton, Jan Pohl, Stephen T Warren. Hum Mol Genet 2003
16
Evidence that fragile X mental retardation protein is a negative regulator of translation.
B Laggerbauer, D Ostareck, E M Keidel, A Ostareck-Lederer, U Fischer. Hum Mol Genet 2001
B Laggerbauer, D Ostareck, E M Keidel, A Ostareck-Lederer, U Fischer. Hum Mol Genet 2001
16
The G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancer.
Marie-Cécile Didiot, Zhaoxia Tian, Céline Schaeffer, Murugan Subramanian, Jean-Louis Mandel, Hervé Moine. Nucleic Acids Res 2008
Marie-Cécile Didiot, Zhaoxia Tian, Céline Schaeffer, Murugan Subramanian, Jean-Louis Mandel, Hervé Moine. Nucleic Acids Res 2008
15
Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction.
Anh Tuân Phan, Vitaly Kuryavyi, Jennifer C Darnell, Alexander Serganov, Ananya Majumdar, Serge Ilin, Tanya Raslin, Anna Polonskaia, Cynthia Chen, David Clain,[...]. Nat Struct Mol Biol 2011
Anh Tuân Phan, Vitaly Kuryavyi, Jennifer C Darnell, Alexander Serganov, Ananya Majumdar, Serge Ilin, Tanya Raslin, Anna Polonskaia, Cynthia Chen, David Clain,[...]. Nat Struct Mol Biol 2011
15
G-quadruplex RNA structure as a signal for neurite mRNA targeting.
Murugan Subramanian, Florence Rage, Ricardos Tabet, Eric Flatter, Jean-Louis Mandel, Hervé Moine. EMBO Rep 2011
Murugan Subramanian, Florence Rage, Ricardos Tabet, Eric Flatter, Jean-Louis Mandel, Hervé Moine. EMBO Rep 2011
15
Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack.
Maile R Brown, Jack Kronengold, Valeswara-Rao Gazula, Yi Chen, John G Strumbos, Fred J Sigworth, Dhasakumar Navaratnam, Leonard K Kaczmarek. Nat Neurosci 2010
Maile R Brown, Jack Kronengold, Valeswara-Rao Gazula, Yi Chen, John G Strumbos, Fred J Sigworth, Dhasakumar Navaratnam, Leonard K Kaczmarek. Nat Neurosci 2010
14
Dysregulation of mTOR signaling in fragile X syndrome.
Ali Sharma, Charles A Hoeffer, Yukihiro Takayasu, Takahiro Miyawaki, Sean M McBride, Eric Klann, R Suzanne Zukin. J Neurosci 2010
Ali Sharma, Charles A Hoeffer, Yukihiro Takayasu, Takahiro Miyawaki, Sean M McBride, Eric Klann, R Suzanne Zukin. J Neurosci 2010
14
Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132.
Dieter Edbauer, Joel R Neilson, Kelly A Foster, Chi-Fong Wang, Daniel P Seeburg, Matthew N Batterton, Tomoko Tada, Bridget M Dolan, Phillip A Sharp, Morgan Sheng. Neuron 2010
Dieter Edbauer, Joel R Neilson, Kelly A Foster, Chi-Fong Wang, Daniel P Seeburg, Matthew N Batterton, Tomoko Tada, Bridget M Dolan, Phillip A Sharp, Morgan Sheng. Neuron 2010
14
RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice.
Kevin Y Miyashiro, Andrea Beckel-Mitchener, T Patrick Purk, Kevin G Becker, Tanya Barret, Lei Liu, Salvatore Carbonetto, Ivan Jeanne Weiler, William T Greenough, James Eberwine. Neuron 2003
Kevin Y Miyashiro, Andrea Beckel-Mitchener, T Patrick Purk, Kevin G Becker, Tanya Barret, Lei Liu, Salvatore Carbonetto, Ivan Jeanne Weiler, William T Greenough, James Eberwine. Neuron 2003
14
Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain.
Leila K Myrick, Hideharu Hashimoto, Xiaodong Cheng, Stephen T Warren. Hum Mol Genet 2015
Leila K Myrick, Hideharu Hashimoto, Xiaodong Cheng, Stephen T Warren. Hum Mol Genet 2015
24
Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them.
M C Siomi, Y Zhang, H Siomi, G Dreyfuss. Mol Cell Biol 1996
M C Siomi, Y Zhang, H Siomi, G Dreyfuss. Mol Cell Biol 1996
13
FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association.
Y Feng, D Absher, D E Eberhart, V Brown, H E Malter, S T Warren. Mol Cell 1997
Y Feng, D Absher, D E Eberhart, V Brown, H E Malter, S T Warren. Mol Cell 1997
13
An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation.
Sunita Kumari, Anthony Bugaut, Julian L Huppert, Shankar Balasubramanian. Nat Chem Biol 2007
Sunita Kumari, Anthony Bugaut, Julian L Huppert, Shankar Balasubramanian. Nat Chem Biol 2007
12
Analysis of FMRP mRNA target datasets reveals highly associated mRNAs mediated by G-quadruplex structures formed via clustered WGGA sequences.
Joshua A Suhl, Pankaj Chopra, Bart R Anderson, Gary J Bassell, Stephen T Warren. Hum Mol Genet 2014
Joshua A Suhl, Pankaj Chopra, Bart R Anderson, Gary J Bassell, Stephen T Warren. Hum Mol Genet 2014
21
rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome.
Chun Kit Kwok, Giovanni Marsico, Aleksandr B Sahakyan, Vicki S Chambers, Shankar Balasubramanian. Nat Methods 2016
Chun Kit Kwok, Giovanni Marsico, Aleksandr B Sahakyan, Vicki S Chambers, Shankar Balasubramanian. Nat Methods 2016
12
FMR1 protein: conserved RNP family domains and selective RNA binding.
C T Ashley, K D Wilkinson, D Reines, S T Warren. Science 1993
C T Ashley, K D Wilkinson, D Reines, S T Warren. Science 1993
12
The fragile X mental retardation protein inhibits translation via interacting with mRNA.
Z Li, Y Zhang, L Ku, K D Wilkinson, S T Warren, Y Feng. Nucleic Acids Res 2001
Z Li, Y Zhang, L Ku, K D Wilkinson, S T Warren, Y Feng. Nucleic Acids Res 2001
12
Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway.
Peng Jin, Daniela C Zarnescu, Stephanie Ceman, Mika Nakamoto, Julie Mowrey, Thomas A Jongens, David L Nelson, Kevin Moses, Stephen T Warren. Nat Neurosci 2004
Peng Jin, Daniela C Zarnescu, Stephanie Ceman, Mika Nakamoto, Julie Mowrey, Thomas A Jongens, David L Nelson, Kevin Moses, Stephen T Warren. Nat Neurosci 2004
12
The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation.
D Devys, Y Lutz, N Rouyer, J P Bellocq, J L Mandel. Nat Genet 1993
D Devys, Y Lutz, N Rouyer, J P Bellocq, J L Mandel. Nat Genet 1993
12
Correction of fragile X syndrome in mice.
Gül Dölen, Emily Osterweil, B S Shankaranarayana Rao, Gordon B Smith, Benjamin D Auerbach, Sumantra Chattarji, Mark F Bear. Neuron 2007
Gül Dölen, Emily Osterweil, B S Shankaranarayana Rao, Gordon B Smith, Benjamin D Auerbach, Sumantra Chattarji, Mark F Bear. Neuron 2007
12
A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P.
A Schenck, B Bardoni, A Moro, C Bagni, J L Mandel. Proc Natl Acad Sci U S A 2001
A Schenck, B Bardoni, A Moro, C Bagni, J L Mandel. Proc Natl Acad Sci U S A 2001
12
HITS-CLIP in various brain areas reveals new targets and new modalities of RNA binding by fragile X mental retardation protein.
Thomas Maurin, Kevin Lebrigand, Sara Castagnola, Agnès Paquet, Marielle Jarjat, Alexandra Popa, Mauro Grossi, Florence Rage, Barbara Bardoni. Nucleic Acids Res 2018
Thomas Maurin, Kevin Lebrigand, Sara Castagnola, Agnès Paquet, Marielle Jarjat, Alexandra Popa, Mauro Grossi, Florence Rage, Barbara Bardoni. Nucleic Acids Res 2018
20
QGRS Mapper: a web-based server for predicting G-quadruplexes in nucleotide sequences.
Oleg Kikin, Lawrence D'Antonio, Paramjeet S Bagga. Nucleic Acids Res 2006
Oleg Kikin, Lawrence D'Antonio, Paramjeet S Bagga. Nucleic Acids Res 2006
11
RNA G-Quadruplexes in Biology: Principles and Molecular Mechanisms.
Marta M Fay, Shawn M Lyons, Pavel Ivanov. J Mol Biol 2017
Marta M Fay, Shawn M Lyons, Pavel Ivanov. J Mol Biol 2017
11
Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures.
Leila K Myrick, Pan-Yue Deng, Hideharu Hashimoto, Young Mi Oh, Yongcheol Cho, Mickael J Poidevin, Joshua A Suhl, Jeannie Visootsak, Valeria Cavalli, Peng Jin,[...]. Proc Natl Acad Sci U S A 2015
Leila K Myrick, Pan-Yue Deng, Hideharu Hashimoto, Young Mi Oh, Yongcheol Cho, Mickael J Poidevin, Joshua A Suhl, Jeannie Visootsak, Valeria Cavalli, Peng Jin,[...]. Proc Natl Acad Sci U S A 2015
14
FMRP interacts with G-quadruplex structures in the 3'-UTR of its dendritic target Shank1 mRNA.
Yang Zhang, Christian M Gaetano, Kathryn R Williams, Gary J Bassell, Mihaela Rita Mihailescu. RNA Biol 2014
Yang Zhang, Christian M Gaetano, Kathryn R Williams, Gary J Bassell, Mihaela Rita Mihailescu. RNA Biol 2014
27
A point mutation in the FMR-1 gene associated with fragile X mental retardation.
K De Boulle, A J Verkerk, E Reyniers, L Vits, J Hendrickx, B Van Roy, F Van den Bos, E de Graaff, B A Oostra, P J Willems. Nat Genet 1993
K De Boulle, A J Verkerk, E Reyniers, L Vits, J Hendrickx, B Van Roy, F Van den Bos, E de Graaff, B A Oostra, P J Willems. Nat Genet 1993
11
G-quartet-dependent recognition between the FMRP RGG box and RNA.
Andres Ramos, David Hollingworth, Annalisa Pastore. RNA 2003
Andres Ramos, David Hollingworth, Annalisa Pastore. RNA 2003
11
A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response.
Roman Alpatov, Bluma J Lesch, Mika Nakamoto-Kinoshita, Andres Blanco, Shuzhen Chen, Alexandra Stützer, Karim J Armache, Matthew D Simon, Chao Xu, Muzaffar Ali,[...]. Cell 2014
Roman Alpatov, Bluma J Lesch, Mika Nakamoto-Kinoshita, Andres Blanco, Shuzhen Chen, Alexandra Stützer, Karim J Armache, Matthew D Simon, Chao Xu, Muzaffar Ali,[...]. Cell 2014
11
The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals.
D E Eberhart, H E Malter, Y Feng, S T Warren. Hum Mol Genet 1996
D E Eberhart, H E Malter, Y Feng, S T Warren. Hum Mol Genet 1996
11
11
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.