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Times Cited: 146
Times Cited
Times Co-cited
Similarity
Localization of the GLYT1 glycine transporter at glutamatergic synapses in the rat brain.
Beatriz Cubelos, Cecilio Giménez, Francisco Zafra. Cereb Cortex 2005
Beatriz Cubelos, Cecilio Giménez, Francisco Zafra. Cereb Cortex 2005
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Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of antipsychotic.
Ronan Depoortère, Gihad Dargazanli, Genevieve Estenne-Bouhtou, Annick Coste, Christophe Lanneau, Christophe Desvignes, Martine Poncelet, Michel Heaulme, Vincent Santucci, Michel Decobert,[...]. Neuropsychopharmacology 2005
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Modulation of N-methyl-D-aspartate receptor function by glycine transport.
R Bergeron, T M Meyer, J T Coyle, R W Greene. Proc Natl Acad Sci U S A 1998
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Glycine potentiates the NMDA response in cultured mouse brain neurons.
J W Johnson, P Ascher. Nature 1987
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The glycine transporter type 1 inhibitor N-[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine potentiates NMDA receptor-mediated responses in vivo and produces an antipsychotic profile in rodent behavior.
Gene G Kinney, Cyrille Sur, Maryann Burno, Pierre J Mallorga, Jacinta B Williams, David J Figueroa, Marion Wittmann, Wei Lemaire, P Jeffrey Conn. J Neurosci 2003
Gene G Kinney, Cyrille Sur, Maryann Burno, Pierre J Mallorga, Jacinta B Williams, David J Figueroa, Marion Wittmann, Wei Lemaire, P Jeffrey Conn. J Neurosci 2003
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N[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine (NFPS) is a selective persistent inhibitor of glycine transport.
K R Aubrey, R J Vandenberg. Br J Pharmacol 2001
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Glycine transporters are differentially expressed among CNS cells.
F Zafra, C Aragón, L Olivares, N C Danbolt, C Giménez, J Storm-Mathisen. J Neurosci 1995
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Volker Eulenburg, Wencke Armsen, Heinrich Betz, Jesús Gomeza. Trends Biochem Sci 2005
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F Zafra, J Gomeza, L Olivares, C Aragón, C Giménez. Eur J Neurosci 1995
F Zafra, J Gomeza, L Olivares, C Aragón, C Giménez. Eur J Neurosci 1995
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Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to antipsychotics for the treatment of schizophrenia.
Guochuan Tsai, Hsien-Yuan Lane, Pinchen Yang, Mian-Yoon Chong, Nicholas Lange. Biol Psychiatry 2004
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Inactivation of the glycine transporter 1 gene discloses vital role of glial glycine uptake in glycinergic inhibition.
Jesús Gomeza, Swen Hülsmann, Koji Ohno, Volker Eulenburg, Katalin Szöke, Diethelm Richter, Heinrich Betz. Neuron 2003
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L G Harsing, Z Juranyi, I Gacsalyi, P Tapolcsanyi, A Czompa, P Matyus. Curr Med Chem 2006
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Laszlo G Harsing, Istvan Gacsalyi, Geza Szabo, Eva Schmidt, Nora Sziray, Claude Sebban, Brigitte Tesolin-Decros, Peter Matyus, Andras Egyed, Michael Spedding,[...]. Pharmacol Biochem Behav 2003
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Neurochemical and behavioral profiling of the selective GlyT1 inhibitors ALX5407 and LY2365109 indicate a preferential action in caudal vs. cortical brain areas.
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Glycine tranporter-1 blockade potentiates NMDA-mediated responses in rat prefrontal cortical neurons in vitro and in vivo.
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Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors.
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Selective GlyT1 inhibitors: discovery of [4-(3-fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methylethoxy)phenyl]methanone (RG1678), a promising novel medicine to treat schizophrenia.
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The first potent and selective inhibitors of the glycine transporter type 2.
W L Caulfield, I T Collie, R S Dickins, O Epemolu, R McGuire, D R Hill, G McVey, J R Morphy, Z Rankovic, H Sundaram. J Med Chem 2001
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Craig W Lindsley, Scott E Wolkenberg, Gene G Kinney. Curr Top Med Chem 2006
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Cloning of the human glycine transporter type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes.
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M J Roux, S Supplisson. Neuron 2000
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Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia.
Tatiana Lipina, Viviane Labrie, Ina Weiner, John Roder. Psychopharmacology (Berl) 2005
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Pharmacological assessment of the role of the glycine transporter GlyT-1 in mediating high-affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomes.
H J Herdon, F M Godfrey, A M Brown, S Coulton, J R Evans, W J Cairns. Neuropharmacology 2001
H J Herdon, F M Godfrey, A M Brown, S Coulton, J R Evans, W J Cairns. Neuropharmacology 2001
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Prepulse inhibition deficits of the startle reflex in neonatal ventral hippocampal-lesioned rats: reversal by glycine and a glycine transporter inhibitor.
Gwenaëlle Le Pen, James Kew, Daniela Alberati, Edilio Borroni, Marie Paule Heitz, Jean-Luc Moreau. Biol Psychiatry 2003
Gwenaëlle Le Pen, James Kew, Daniela Alberati, Edilio Borroni, Marie Paule Heitz, Jean-Luc Moreau. Biol Psychiatry 2003
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Pharmacology and expression analysis of glycine transporter GlyT1 with [3H]-(N-[3-(4'-fluorophenyl)-3-(4'phenylphenoxy)propyl])sarcosine.
Pierre J Mallorga, Jacinta B Williams, Marlene Jacobson, Rosemary Marques, Ashok Chaudhary, P Jeffrey Conn, Douglas J Pettibone, Cyrille Sur. Neuropharmacology 2003
Pierre J Mallorga, Jacinta B Williams, Marlene Jacobson, Rosemary Marques, Ashok Chaudhary, P Jeffrey Conn, Douglas J Pettibone, Cyrille Sur. Neuropharmacology 2003
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Two glycine transporter variants with distinct localization in the CNS and peripheral tissues are encoded by a common gene.
B Borowsky, E Mezey, B J Hoffman. Neuron 1993
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Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels.
Marzia Martina, Yelena Gorfinkel, Samantha Halman, John A Lowe, Pranav Periyalwar, Christopher J Schmidt, Richard Bergeron. J Physiol 2004
Marzia Martina, Yelena Gorfinkel, Samantha Halman, John A Lowe, Pranav Periyalwar, Christopher J Schmidt, Richard Bergeron. J Physiol 2004
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Disruption of glycine transporter 1 restricted to forebrain neurons is associated with a procognitive and antipsychotic phenotypic profile.
Benjamin K Yee, Ela Balic, Philipp Singer, Cornelia Schwerdel, Thomas Grampp, Laetitia Gabernet, Irene Knuesel, Dietmar Benke, Joram Feldon, Hanns Mohler,[...]. J Neurosci 2006
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Gene knockout of glycine transporter 1: characterization of the behavioral phenotype.
Guochuan Tsai, Rebecca J Ralph-Williams, Marzia Martina, Richard Bergeron, Joanne Berger-Sweeney, Kevin S Dunham, Zhichun Jiang, S Barak Caine, Joseph T Coyle. Proc Natl Acad Sci U S A 2004
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Characterization of SSR103800, a selective inhibitor of the glycine transporter-1 in models predictive of therapeutic activity in schizophrenia.
Denis Boulay, Philippe Pichat, Gihad Dargazanli, Genevieve Estenne-Bouhtou, Jean Paul Terranova, Nancy Rogacki, Jeanne Stemmelin, Annick Coste, Christophe Lanneau, Christophe Desvignes,[...]. Pharmacol Biochem Behav 2008
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Inhibitors of GlyT1 affect glycine transport via discrete binding sites.
Mario Mezler, Wilfried Hornberger, Reinhold Mueller, Martin Schmidt, Willi Amberg, Wilfried Braje, Michael Ochse, Hans Schoemaker, Berthold Behl. Mol Pharmacol 2008
Mario Mezler, Wilfried Hornberger, Reinhold Mueller, Martin Schmidt, Willi Amberg, Wilfried Braje, Michael Ochse, Hans Schoemaker, Berthold Behl. Mol Pharmacol 2008
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Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study.
Hsien-Yuan Lane, Yue-Cune Chang, Yi-Ching Liu, Chih-Chiang Chiu, Guochuan E Tsai. Arch Gen Psychiatry 2005
Hsien-Yuan Lane, Yue-Cune Chang, Yi-Ching Liu, Chih-Chiang Chiu, Guochuan E Tsai. Arch Gen Psychiatry 2005
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Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia.
U Heresco-Levy, D C Javitt, M Ermilov, C Mordel, G Silipo, M Lichtenstein. Arch Gen Psychiatry 1999
U Heresco-Levy, D C Javitt, M Ermilov, C Mordel, G Silipo, M Lichtenstein. Arch Gen Psychiatry 1999
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Glycine transporters: crucial roles of pharmacological interest revealed by gene deletion.
Carmen Aragón, Beatriz López-Corcuera. Trends Pharmacol Sci 2005
Carmen Aragón, Beatriz López-Corcuera. Trends Pharmacol Sci 2005
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Deletion of the mouse glycine transporter 2 results in a hyperekplexia phenotype and postnatal lethality.
Jesús Gomeza, Koji Ohno, Swen Hülsmann, Wencke Armsen, Volker Eulenburg, Diethelm W Richter, Bodo Laube, Heinrich Betz. Neuron 2003
Jesús Gomeza, Koji Ohno, Swen Hülsmann, Wencke Armsen, Volker Eulenburg, Diethelm W Richter, Bodo Laube, Heinrich Betz. Neuron 2003
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Design, synthesis, and in vivo efficacy of glycine transporter-1 (GlyT1) inhibitors derived from a series of [4-phenyl-1-(propylsulfonyl)piperidin-4-yl]methyl benzamides.
Craig W Lindsley, Zhijian Zhao, William H Leister, Julie O'Brien, Wei Lemaire, David L Williams, Tsing-Bau Chen, Raymond S L Chang, Maryann Burno, Marlene A Jacobson,[...]. ChemMedChem 2006
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The therapeutic potential of glycine transporter-1 inhibitors.
Cyrille Sur, Gene G Kinney. Expert Opin Investig Drugs 2004
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Glycine transporter 1 inhibitors and modulation of NMDA receptor-mediated excitatory neurotransmission.
Cyrille Sur, Gene G Kinney. Curr Drug Targets 2007
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Why glycine transporters have different stoichiometries.
Stéphane Supplisson, Michel J Roux. FEBS Lett 2002
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Glycine transport inhibitors for the treatment of schizophrenia: symptom and disease modification.
Daniel C Javitt. Curr Opin Drug Discov Devel 2009
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Discovery of N-(2-hydroxy-2-aryl-cyclohexyl) substituted spiropiperidines as GlyT1 antagonists with improved pharmacological profile.
Simona M Ceccarelli, Emmanuel Pinard, Henri Stalder, Daniela Alberati. Bioorg Med Chem Lett 2006
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High-dose glycine added to olanzapine and risperidone for the treatment of schizophrenia.
Uriel Heresco-Levy, Marina Ermilov, Pesah Lichtenberg, Gali Bar, Daniel C Javitt. Biol Psychiatry 2004
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Glutamate and schizophrenia: beyond the dopamine hypothesis.
Joseph T Coyle. Cell Mol Neurobiol 2006
Joseph T Coyle. Cell Mol Neurobiol 2006
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Discovery of benzoylpiperazines as a novel class of potent and selective GlyT1 inhibitors.
Emmanuel Pinard, Daniela Alberati, Edilio Borroni, Holger Fischer, Dominik Hainzl, Synèse Jolidon, Jean-Luc Moreau, Robert Narquizian, Matthias Nettekoven, Roger D Norcross,[...]. Bioorg Med Chem Lett 2008
Emmanuel Pinard, Daniela Alberati, Edilio Borroni, Holger Fischer, Dominik Hainzl, Synèse Jolidon, Jean-Luc Moreau, Robert Narquizian, Matthias Nettekoven, Roger D Norcross,[...]. Bioorg Med Chem Lett 2008
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Recent progress in the discovery of non-sarcosine based GlyT1 inhibitors.
Scott E Wolkenberg, Cyrille Sur. Curr Top Med Chem 2010
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Control of NMDA receptor activation by a glycine transporter co-expressed in Xenopus oocytes.
S Supplisson, C Bergman. J Neurosci 1997
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.