K R Aubrey, R J Vandenberg. Br J Pharmacol 2001
Times Cited: 78
Times Cited: 78
Times Cited
Times Co-cited
Similarity
ALX 5407: a potent, selective inhibitor of the hGlyT1 glycine transporter.
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Modulation of N-methyl-D-aspartate receptor function by glycine transport.
R Bergeron, T M Meyer, J T Coyle, R W Greene. Proc Natl Acad Sci U S A 1998
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Glycine potentiates the NMDA response in cultured mouse brain neurons.
J W Johnson, P Ascher. Nature 1987
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Glycine transporters are differentially expressed among CNS cells.
F Zafra, C Aragón, L Olivares, N C Danbolt, C Giménez, J Storm-Mathisen. J Neurosci 1995
F Zafra, C Aragón, L Olivares, N C Danbolt, C Giménez, J Storm-Mathisen. J Neurosci 1995
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Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors.
K E Smith, L A Borden, P R Hartig, T Branchek, R L Weinshank. Neuron 1992
K E Smith, L A Borden, P R Hartig, T Branchek, R L Weinshank. Neuron 1992
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Cloning of the human glycine transporter type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes.
K M Kim, S F Kingsmore, H Han, T L Yang-Feng, N Godinot, M F Seldin, M G Caron, B Giros. Mol Pharmacol 1994
K M Kim, S F Kingsmore, H Han, T L Yang-Feng, N Godinot, M F Seldin, M G Caron, B Giros. Mol Pharmacol 1994
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Regional distribution and developmental variation of the glycine transporters GLYT1 and GLYT2 in the rat CNS.
F Zafra, J Gomeza, L Olivares, C Aragón, C Giménez. Eur J Neurosci 1995
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Glycine tranporter-1 blockade potentiates NMDA-mediated responses in rat prefrontal cortical neurons in vitro and in vivo.
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The glycine transporter-1 inhibitors NFPS and Org 24461: a pharmacological study.
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Control of NMDA receptor activation by a glycine transporter co-expressed in Xenopus oocytes.
S Supplisson, C Bergman. J Neurosci 1997
S Supplisson, C Bergman. J Neurosci 1997
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Neuronal and glial glycine transporters have different stoichiometries.
M J Roux, S Supplisson. Neuron 2000
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Recent advances in the phencyclidine model of schizophrenia.
D C Javitt, S R Zukin. Am J Psychiatry 1991
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Localization of the GLYT1 glycine transporter at glutamatergic synapses in the rat brain.
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Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of antipsychotic.
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Two glycine transporter variants with distinct localization in the CNS and peripheral tissues are encoded by a common gene.
B Borowsky, E Mezey, B J Hoffman. Neuron 1993
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Inactivation of the glycine transporter 1 gene discloses vital role of glial glycine uptake in glycinergic inhibition.
Jesús Gomeza, Swen Hülsmann, Koji Ohno, Volker Eulenburg, Katalin Szöke, Diethelm Richter, Heinrich Betz. Neuron 2003
Jesús Gomeza, Swen Hülsmann, Koji Ohno, Volker Eulenburg, Katalin Szöke, Diethelm Richter, Heinrich Betz. Neuron 2003
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W Danysz, C G Parsons. Pharmacol Rev 1998
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Pharmacology and expression analysis of glycine transporter GlyT1 with [3H]-(N-[3-(4'-fluorophenyl)-3-(4'phenylphenoxy)propyl])sarcosine.
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Discovery and SAR of org 24598-a selective glycine uptake inhibitor.
A Brown, I Carlyle, J Clark, W Hamilton, S Gibson, G McGarry, S McEachen, D Rae, S Thorn, G Walker. Bioorg Med Chem Lett 2001
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Cloning and expression of a spinal cord- and brain-specific glycine transporter with novel structural features.
Q R Liu, B López-Corcuera, S Mandiyan, H Nelson, N Nelson. J Biol Chem 1993
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Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to antipsychotics for the treatment of schizophrenia.
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Gene knockout of glycine transporter 1: characterization of the behavioral phenotype.
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Cloning, expression, and localization of a rat brain high-affinity glycine transporter.
J Guastella, N Brecha, C Weigmann, H A Lester, N Davidson. Proc Natl Acad Sci U S A 1992
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Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels.
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Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses.
A J Berger, S Dieudonné, P Ascher. J Neurophysiol 1998
A J Berger, S Dieudonné, P Ascher. J Neurophysiol 1998
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Pharmacological assessment of the role of the glycine transporter GlyT-1 in mediating high-affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomes.
H J Herdon, F M Godfrey, A M Brown, S Coulton, J R Evans, W J Cairns. Neuropharmacology 2001
H J Herdon, F M Godfrey, A M Brown, S Coulton, J R Evans, W J Cairns. Neuropharmacology 2001
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Prepulse inhibition deficits of the startle reflex in neonatal ventral hippocampal-lesioned rats: reversal by glycine and a glycine transporter inhibitor.
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Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia.
U Heresco-Levy, D C Javitt, M Ermilov, C Mordel, G Silipo, M Lichtenstein. Arch Gen Psychiatry 1999
U Heresco-Levy, D C Javitt, M Ermilov, C Mordel, G Silipo, M Lichtenstein. Arch Gen Psychiatry 1999
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Glycine transporters: essential regulators of neurotransmission.
Volker Eulenburg, Wencke Armsen, Heinrich Betz, Jesús Gomeza. Trends Biochem Sci 2005
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Amelioration of negative symptoms in schizophrenia by glycine.
D C Javitt, I Zylberman, S R Zukin, U Heresco-Levy, J P Lindenmayer. Am J Psychiatry 1994
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The therapeutic potential of glycine transporter-1 inhibitors.
Cyrille Sur, Gene G Kinney. Expert Opin Investig Drugs 2004
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Cloning and expression of a glycine transporter from mouse brain.
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The first potent and selective inhibitors of the glycine transporter type 2.
W L Caulfield, I T Collie, R S Dickins, O Epemolu, R McGuire, D R Hill, G McVey, J R Morphy, Z Rankovic, H Sundaram. J Med Chem 2001
W L Caulfield, I T Collie, R S Dickins, O Epemolu, R McGuire, D R Hill, G McVey, J R Morphy, Z Rankovic, H Sundaram. J Med Chem 2001
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NMDA receptor hypofunction model of schizophrenia.
J W Olney, J W Newcomer, N B Farber. J Psychiatr Res 1999
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Reversal of phencyclidine-induced hyperactivity by glycine and the glycine uptake inhibitor glycyldodecylamide.
D C Javitt, H Sershen, A Hashim, A Lajtha. Neuropsychopharmacology 1997
D C Javitt, H Sershen, A Hashim, A Lajtha. Neuropsychopharmacology 1997
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Why glycine transporters have different stoichiometries.
Stéphane Supplisson, Michel J Roux. FEBS Lett 2002
Stéphane Supplisson, Michel J Roux. FEBS Lett 2002
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[3H]-(R)-NPTS, a radioligand for the type 1 glycine transporter.
John A Lowe, Susan E Drozda, Katherine Fisher, Christine Strick, Lorraine Lebel, Christopher Schmidt, Donna Hiller, Kathleen S Zandi. Bioorg Med Chem Lett 2003
John A Lowe, Susan E Drozda, Katherine Fisher, Christine Strick, Lorraine Lebel, Christopher Schmidt, Donna Hiller, Kathleen S Zandi. Bioorg Med Chem Lett 2003
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Neurochemical and behavioral profiling of the selective GlyT1 inhibitors ALX5407 and LY2365109 indicate a preferential action in caudal vs. cortical brain areas.
Kenneth W Perry, Julie F Falcone, Matthew J Fell, John W Ryder, Hong Yu, Patrick L Love, Jason Katner, Kimberly D Gordon, Mark R Wade, Teresa Man,[...]. Neuropharmacology 2008
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20
Inhibitors of GlyT1 affect glycine transport via discrete binding sites.
Mario Mezler, Wilfried Hornberger, Reinhold Mueller, Martin Schmidt, Willi Amberg, Wilfried Braje, Michael Ochse, Hans Schoemaker, Berthold Behl. Mol Pharmacol 2008
Mario Mezler, Wilfried Hornberger, Reinhold Mueller, Martin Schmidt, Willi Amberg, Wilfried Braje, Michael Ochse, Hans Schoemaker, Berthold Behl. Mol Pharmacol 2008
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Analysis of a gene encoding two glycine transporter variants reveals alternative promoter usage and a novel gene structure.
B Borowsky, B J Hoffman. J Biol Chem 1998
B Borowsky, B J Hoffman. J Biol Chem 1998
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Differential properties of two stably expressed brain-specific glycine transporters.
B López-Corcuera, R Martínez-Maza, E Núñez, M Roux, S Supplisson, C Aragón. J Neurochem 1998
B López-Corcuera, R Martínez-Maza, E Núñez, M Roux, S Supplisson, C Aragón. J Neurochem 1998
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High-dose glycine added to olanzapine and risperidone for the treatment of schizophrenia.
Uriel Heresco-Levy, Marina Ermilov, Pesah Lichtenberg, Gali Bar, Daniel C Javitt. Biol Psychiatry 2004
Uriel Heresco-Levy, Marina Ermilov, Pesah Lichtenberg, Gali Bar, Daniel C Javitt. Biol Psychiatry 2004
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Deletion of the mouse glycine transporter 2 results in a hyperekplexia phenotype and postnatal lethality.
Jesús Gomeza, Koji Ohno, Swen Hülsmann, Wencke Armsen, Volker Eulenburg, Diethelm W Richter, Bodo Laube, Heinrich Betz. Neuron 2003
Jesús Gomeza, Koji Ohno, Swen Hülsmann, Wencke Armsen, Volker Eulenburg, Diethelm W Richter, Bodo Laube, Heinrich Betz. Neuron 2003
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Enhancement of the NMDA receptor function by reduction of glycine transporter-1 expression.
Laetitia Gabernet, Meike Pauly-Evers, Cornelia Schwerdel, Michèle Lentz, Horst Bluethmann, Kaspar Vogt, Daniela Alberati, Hanns Mohler, Detlev Boison. Neurosci Lett 2005
Laetitia Gabernet, Meike Pauly-Evers, Cornelia Schwerdel, Michèle Lentz, Horst Bluethmann, Kaspar Vogt, Daniela Alberati, Hanns Mohler, Detlev Boison. Neurosci Lett 2005
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Characterization of SSR103800, a selective inhibitor of the glycine transporter-1 in models predictive of therapeutic activity in schizophrenia.
Denis Boulay, Philippe Pichat, Gihad Dargazanli, Genevieve Estenne-Bouhtou, Jean Paul Terranova, Nancy Rogacki, Jeanne Stemmelin, Annick Coste, Christophe Lanneau, Christophe Desvignes,[...]. Pharmacol Biochem Behav 2008
Denis Boulay, Philippe Pichat, Gihad Dargazanli, Genevieve Estenne-Bouhtou, Jean Paul Terranova, Nancy Rogacki, Jeanne Stemmelin, Annick Coste, Christophe Lanneau, Christophe Desvignes,[...]. Pharmacol Biochem Behav 2008
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Glycyldodecylamide, a phencyclidine behavioral antagonist, blocks cortical glycine uptake: implications for schizophrenia and substance abuse.
D C Javitt, M Frusciante. Psychopharmacology (Berl) 1997
D C Javitt, M Frusciante. Psychopharmacology (Berl) 1997
19
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