A citation-based method for searching scientific literature

C H Kwon, X Zhu, J Zhang, L L Knoop, R Tharp, R J Smeyne, C G Eberhart, P C Burger, S J Baker. Nat Genet 2001
Times Cited: 340







List of co-cited articles
853 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease.
S A Backman, V Stambolic, A Suzuki, J Haight, A Elia, J Pretorius, M S Tsao, P Shannon, B Bolon, G O Ivy,[...]. Nat Genet 2001
366
67

Pten regulates neuronal arborization and social interaction in mice.
Chang-Hyuk Kwon, Bryan W Luikart, Craig M Powell, Jing Zhou, Sharon A Matheny, Wei Zhang, Yanjiao Li, Suzanne J Baker, Luis F Parada. Neuron 2006
675
47

Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations.
M G Butler, M J Dasouki, X-P Zhou, Z Talebizadeh, M Brown, T N Takahashi, J H Miles, C H Wang, R Stratton, R Pilarski,[...]. J Med Genet 2005
515
28

Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice.
Jing Zhou, Jacqueline Blundell, Shiori Ogawa, Chang-Hyuk Kwon, Wei Zhang, Christopher Sinton, Craig M Powell, Luis F Parada. J Neurosci 2009
296
27

Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.
M Groszer, R Erickson, D D Scripture-Adams, R Lesche, A Trumpp, J A Zack, H I Kornblum, X Liu, H Wu. Science 2001
633
22

The prevalence of PTEN mutations in a clinical pediatric cohort with autism spectrum disorders, developmental delay, and macrocephaly.
Elizabeth A Varga, Matthew Pastore, Thomas Prior, Gail E Herman, Kim L McBride. Genet Med 2009
193
21

Excessive activation of mTOR in postnatally generated granule cells is sufficient to cause epilepsy.
Raymund Y K Pun, Isaiah J Rolle, Candi L Lasarge, Bethany E Hosford, Jules M Rosen, Juli D Uhl, Sarah N Schmeltzer, Christian Faulkner, Stefanie L Bronson, Brian L Murphy,[...]. Neuron 2012
178
21

Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia.
M Cecilia Ljungberg, C Nicole Sunnen, Joaquin N Lugo, Anne E Anderson, Gabriella D'Arcangelo. Dis Model Mech 2009
126
21

Pten loss causes hypertrophy and increased proliferation of astrocytes in vivo.
Melissa M Fraser, Xiaoyan Zhu, Chang-Hyuk Kwon, Erik J Uhlmann, David H Gutmann, Suzanne J Baker. Cancer Res 2004
169
20

Phosphatase and tensin homologue (PTEN) regulates synaptic plasticity independently of its effect on neuronal morphology and migration.
Margaret Sperow, Raymond B Berry, Ildar T Bayazitov, Guo Zhu, Suzanne J Baker, Stanislav S Zakharenko. J Physiol 2012
74
27


mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo.
Chang-Hyuk Kwon, Xiaoyan Zhu, Junyuan Zhang, Suzanne J Baker. Proc Natl Acad Sci U S A 2003
191
19

Pten knockdown in vivo increases excitatory drive onto dentate granule cells.
Bryan W Luikart, Eric Schnell, Eric K Washburn, Aesoon L Bensen, Kenneth R Tovar, Gary L Westbrook. J Neurosci 2011
102
18

Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins.
Joaquin N Lugo, Gregory D Smith, Erin P Arbuckle, Jessika White, Andrew J Holley, Crina M Floruta, Nowrin Ahmed, Maribel C Gomez, Obi Okonkwo. Front Mol Neurosci 2014
94
19

Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis.
Anahita Amiri, Woosung Cho, Jing Zhou, Shari G Birnbaum, Christopher M Sinton, Renée M McKay, Luis F Parada. J Neurosci 2012
129
17

Mutation screening of the PTEN gene in patients with autism spectrum disorders and macrocephaly.
Joseph D Buxbaum, Guiqing Cai, Pauline Chaste, Gudrun Nygren, Juliet Goldsmith, Jennifer Reichert, Henrik Anckarsäter, Maria Rastam, Christopher J Smith, Jeremy M Silverman,[...]. Am J Med Genet B Neuropsychiatr Genet 2007
181
17

Confirmation study of PTEN mutations among individuals with autism or developmental delays/mental retardation and macrocephaly.
Kim L McBride, Elizabeth A Varga, Matthew T Pastore, Thomas W Prior, Kandamurugu Manickam, Joan F Atkin, Gail E Herman. Autism Res 2010
164
17


PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer.
J Li, C Yen, D Liaw, K Podsypanina, S Bose, S I Wang, J Puc, C Miliaresis, L Rodgers, R McCombie,[...]. Science 1997
16


Pten is essential for embryonic development and tumour suppression.
A Di Cristofano, B Pesce, C Cordon-Cardo, P P Pandolfi. Nat Genet 1998
15

PTEN signaling in autism spectrum disorders.
Jing Zhou, Luis F Parada. Curr Opin Neurobiol 2012
124
15

Molecular and phenotypic abnormalities in individuals with germline heterozygous PTEN mutations and autism.
T W Frazier, R Embacher, A K Tilot, K Koenig, J Mester, C Eng. Mol Psychiatry 2015
95
15

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome.
D Liaw, D J Marsh, J Li, P L Dahia, S I Wang, Z Zheng, S Bose, K M Call, H C Tsou, M Peacocke,[...]. Nat Genet 1997
14

The functions and regulation of the PTEN tumour suppressor.
Min Sup Song, Leonardo Salmena, Pier Paolo Pandolfi. Nat Rev Mol Cell Biol 2012
13

Hyperactivity of newborn Pten knock-out neurons results from increased excitatory synaptic drive.
Michael R Williams, Tyrone DeSpenza, Meijie Li, Allan T Gulledge, Bryan W Luikart. J Neurosci 2015
71
18

PTEN mutation in a family with Cowden syndrome and autism.
A Goffin, L H Hoefsloot, E Bosgoed, A Swillen, J P Fryns. Am J Med Genet 2001
153
12

PTEN is essential for cell migration but not for fate determination and tumourigenesis in the cerebellum.
Silvia Marino, Paul Krimpenfort, Carly Leung, Hetty A G M van der Korput, Jan Trapman, Isabelle Camenisch, Anton Berns, Sebastian Brandner. Development 2002
145
12

Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism.
Koichi Takeuchi, Michael J Gertner, Jing Zhou, Luis F Parada, Michael V L Bennett, R Suzanne Zukin. Proc Natl Acad Sci U S A 2013
80
15

A seizure-prone phenotype is associated with altered free-running rhythm in Pten mutant mice.
Shiori Ogawa, Chang-Hyuk Kwon, Jing Zhou, Della Koovakkattu, Luis F Parada, Christopher M Sinton. Brain Res 2007
56
21

Haploinsufficiency for Pten and Serotonin transporter cooperatively influences brain size and social behavior.
Damon T Page, Orsolya J Kuti, Chrysa Prestia, Mriganka Sur. Proc Natl Acad Sci U S A 2009
108
12

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers.
P A Steck, M A Pershouse, S A Jasser, W K Yung, H Lin, A H Ligon, L A Langford, M L Baumgard, T Hattier, T Davis,[...]. Nat Genet 1997
11

Increasing knowledge of PTEN germline mutations: Two additional patients with autism and macrocephaly.
Gail E Herman, Eric Butter, Benedicta Enrile, Matthew Pastore, Thomas W Prior, Annemarie Sommer. Am J Med Genet A 2007
118
11


Germline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production.
Amanda K Tilot, Mary K Gaugler, Qi Yu, Todd Romigh, Wanfeng Yu, Robert H Miller, Thomas W Frazier, Charis Eng. Hum Mol Genet 2014
42
26

Synaptic, transcriptional and chromatin genes disrupted in autism.
Silvia De Rubeis, Xin He, Arthur P Goldberg, Christopher S Poultney, Kaitlin Samocha, A Erucment Cicek, Yan Kou, Li Liu, Menachem Fromer, Susan Walker,[...]. Nature 2014
11

mTOR inhibition suppresses established epilepsy in a mouse model of cortical dysplasia.
Lena H Nguyen, Amy L Brewster, Madeline E Clark, Angelique Regnier-Golanov, C Nicole Sunnen, Vinit V Patil, Gabriella D'Arcangelo, Anne E Anderson. Epilepsia 2015
52
21

Autistic-Like Traits and Cerebellar Dysfunction in Purkinje Cell PTEN Knock-Out Mice.
Dario Cupolillo, Eriola Hoxha, Alessio Faralli, Annarita De Luca, Ferdinando Rossi, Filippo Tempia, Daniela Carulli. Neuropsychopharmacology 2016
71
15

PTEN: one gene, many syndromes.
Charis Eng. Hum Mutat 2003
574
10

De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly.
Jeong Ho Lee, My Huynh, Jennifer L Silhavy, Sangwoo Kim, Tracy Dixon-Salazar, Andrew Heiberg, Eric Scott, Vineet Bafna, Kiley J Hill, Adrienne Collazo,[...]. Nat Genet 2012
423
10

Ubiquitination regulates PTEN nuclear import and tumor suppression.
Lloyd C Trotman, Xinjiang Wang, Andrea Alimonti, Zhenbang Chen, Julie Teruya-Feldstein, Haijuan Yang, Nikola P Pavletich, Brett S Carver, Carlos Cordon-Cardo, Hediye Erdjument-Bromage,[...]. Cell 2007
548
10

PI3K/AKT pathway mutations cause a spectrum of brain malformations from megalencephaly to focal cortical dysplasia.
Laura A Jansen, Ghayda M Mirzaa, Gisele E Ishak, Brian J O'Roak, Joseph B Hiatt, William H Roden, Sonya A Gunter, Susan L Christian, Sarah Collins, Carissa Adams,[...]. Brain 2015
191
10

Pten Mutations Alter Brain Growth Trajectory and Allocation of Cell Types through Elevated β-Catenin Signaling.
Youjun Chen, Wen-Chin Huang, Julien Séjourné, Amy E Clipperton-Allen, Damon T Page. J Neurosci 2015
66
15

A clinical scoring system for selection of patients for PTEN mutation testing is proposed on the basis of a prospective study of 3042 probands.
Min-Han Tan, Jessica Mester, Charissa Peterson, Yiran Yang, Jin-Lian Chen, Lisa A Rybicki, Kresimira Milas, Holly Pederson, Berna Remzi, Mohammed S Orloff,[...]. Am J Hum Genet 2011
231
9

Novel PTEN mutations in neurodevelopmental disorders and macrocephaly.
A Orrico, L Galli, S Buoni, A Orsi, G Vonella, V Sorrentino. Clin Genet 2009
80
11

PTEN and the PI3-kinase pathway in cancer.
Nader Chalhoub, Suzanne J Baker. Annu Rev Pathol 2009
789
9


PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry.
Matthias Groszer, Rebecca Erickson, Deirdre D Scripture-Adams, Joseph D Dougherty, Janel Le Belle, Jerome A Zack, Daniel H Geschwind, Xin Liu, Harley I Kornblum, Hong Wu. Proc Natl Acad Sci U S A 2006
242
9

Inhibition of the mammalian target of rapamycin blocks epilepsy progression in NS-Pten conditional knockout mice.
C Nicole Sunnen, Amy L Brewster, Joaquin N Lugo, Fabiola Vanegas, Eric Turcios, Shivani Mukhi, Deena Parghi, Gabriella D'Arcangelo, Anne E Anderson. Epilepsia 2011
83
10



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.