A citation-based method for searching scientific literature

Tomomi Shiiya, Masamitsu Nakazato, Masanari Mizuta, Yukari Date, Muhtashan S Mondal, Muneki Tanaka, Shin-Ichi Nozoe, Hiroshi Hosoda, Kenji Kangawa, Shigeru Matsukura. J Clin Endocrinol Metab 2002
Times Cited: 992







List of co-cited articles
1345 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Ghrelin is a growth-hormone-releasing acylated peptide from stomach.
M Kojima, H Hosoda, Y Date, M Nakazato, H Matsuo, K Kangawa. Nature 1999
44

Circulating ghrelin levels are decreased in human obesity.
M Tschöp, C Weyer, P A Tataranni, V Devanarayan, E Ravussin, M L Heiman. Diabetes 2001
34

A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans.
D E Cummings, J Q Purnell, R S Frayo, K Schmidova, B E Wisse, D S Weigle. Diabetes 2001
32

Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone.
Jing Yang, Michael S Brown, Guosheng Liang, Nick V Grishin, Joseph L Goldstein. Cell 2008
844
25

Ghrelin induces adiposity in rodents.
M Tschöp, D L Smiley, M L Heiman. Nature 2000
23

Ghrelin.
T D Müller, R Nogueiras, M L Andermann, Z B Andrews, S D Anker, J Argente, R L Batterham, S C Benoit, C Y Bowers, F Broglio,[...]. Mol Metab 2015
580
23

Ghrelin octanoylation mediated by an orphan lipid transferase.
Jesus A Gutierrez, Patricia J Solenberg, Douglas R Perkins, Jill A Willency, Michael D Knierman, Zhaoyan Jin, Derrick R Witcher, Shuang Luo, Jude E Onyia, John E Hale. Proc Natl Acad Sci U S A 2008
627
22

Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery.
David E Cummings, David S Weigle, R Scott Frayo, Patricia A Breen, Marina K Ma, E Patchen Dellinger, Jonathan Q Purnell. N Engl J Med 2002
19

Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans.
Y Date, M Kojima, H Hosoda, A Sawaguchi, M S Mondal, T Suganuma, S Matsukura, K Kangawa, M Nakazato. Endocrinology 2000
18

A role for ghrelin in the central regulation of feeding.
M Nakazato, N Murakami, Y Date, M Kojima, H Matsuo, K Kangawa, S Matsukura. Nature 2001
16

Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans.
F Broglio, E Arvat, A Benso, C Gottero, G Muccioli, M Papotti, A J van der Lely, R Deghenghi, E Ghigo. J Clin Endocrinol Metab 2001
544
15

Ghrelin enhances appetite and increases food intake in humans.
A M Wren, L J Seal, M A Cohen, A E Brynes, G S Frost, K G Murphy, W S Dhillo, M A Ghatei, S R Bloom. J Clin Endocrinol Metab 2001
14

The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans.
Sharmilee Gnanapavan, Blerina Kola, Stephen A Bustin, Damian G Morris, Patrick McGee, Peter Fairclough, Satya Bhattacharya, Robert Carpenter, Ashley B Grossman, Márta Korbonits. J Clin Endocrinol Metab 2002
14

The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis.
Michael A Cowley, Roy G Smith, Sabrina Diano, Matthias Tschöp, Nina Pronchuk, Kevin L Grove, Christian J Strasburger, Martin Bidlingmaier, Michael Esterman, Mark L Heiman,[...]. Neuron 2003
13

Expression of ghrelin receptor mRNA in the rat and the mouse brain.
Jeffrey M Zigman, Juli E Jones, Charlotte E Lee, Clifford B Saper, Joel K Elmquist. J Comp Neurol 2006
741
13

Ghrelin: structure and function.
Masayasu Kojima, Kenji Kangawa. Physiol Rev 2005
13

Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice.
Tong-Jin Zhao, Guosheng Liang, Robert Lin Li, Xuefen Xie, Mark W Sleeman, Andrew J Murphy, David M Valenzuela, George D Yancopoulos, Joseph L Goldstein, Michael S Brown. Proc Natl Acad Sci U S A 2010
334
12

Endogenous ghrelin in pancreatic islets restricts insulin release by attenuating Ca2+ signaling in beta-cells: implication in the glycemic control in rodents.
Katsuya Dezaki, Hiroshi Hosoda, Masafumi Kakei, Suzuko Hashiguchi, Masatomo Watanabe, Kenji Kangawa, Toshihiko Yada. Diabetes 2004
279
12

LEAP2 Is an Endogenous Antagonist of the Ghrelin Receptor.
Xuecai Ge, Hong Yang, Maria A Bednarek, Hadas Galon-Tilleman, Peirong Chen, Michael Chen, Joshua S Lichtman, Yan Wang, Olivier Dalmas, Yiyuan Yin,[...]. Cell Metab 2018
135
12

A receptor in pituitary and hypothalamus that functions in growth hormone release.
A D Howard, S D Feighner, D F Cully, J P Arena, P A Liberator, C I Rosenblum, M Hamelin, D L Hreniuk, O C Palyha, J Anderson,[...]. Science 1996
12

The Homeostatic Force of Ghrelin.
Shigehisa Yanagi, Takahiro Sato, Kenji Kangawa, Masamitsu Nakazato. Cell Metab 2018
117
12

Acyl and total ghrelin are suppressed strongly by ingested proteins, weakly by lipids, and biphasically by carbohydrates.
Karen E Foster-Schubert, Joost Overduin, Catherine E Prudom, Jianhua Liu, Holly S Callahan, Bruce D Gaylinn, Michael O Thorner, David E Cummings. J Clin Endocrinol Metab 2008
199
12

Obesity Impairs the Action of the Neuroendocrine Ghrelin System.
Jeffrey M Zigman, Sebastien G Bouret, Zane B Andrews. Trends Endocrinol Metab 2016
83
13

Ghrelin suppresses glucose-stimulated insulin secretion and deteriorates glucose tolerance in healthy humans.
Jenny Tong, Ronald L Prigeon, Harold W Davis, Martin Bidlingmaier, Steven E Kahn, David E Cummings, Matthias H Tschöp, David D'Alessio. Diabetes 2010
235
11

Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice.
Yuxiang Sun, Mark Asnicar, Pradip K Saha, Lawrence Chan, Roy G Smith. Cell Metab 2006
277
11

Low plasma ghrelin is associated with insulin resistance, hypertension, and the prevalence of type 2 diabetes.
Seppo M Pöykkö, Eija Kellokoski, Sohvi Hörkkö, Heikki Kauma, Y Antero Kesäniemi, Olavi Ukkola. Diabetes 2003
412
11

LEAP2 changes with body mass and food intake in humans and mice.
Bharath K Mani, Nancy Puzziferri, Zhenyan He, Juan A Rodriguez, Sherri Osborne-Lawrence, Nathan P Metzger, Navpreet Chhina, Bruce Gaylinn, Michael O Thorner, E Louise Thomas,[...]. J Clin Invest 2019
72
15

Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite.
Alfonso Abizaid, Zhong-Wu Liu, Zane B Andrews, Marya Shanabrough, Erzsebet Borok, John D Elsworth, Robert H Roth, Mark W Sleeman, Marina R Picciotto, Matthias H Tschöp,[...]. J Clin Invest 2006
685
10

Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin.
A Asakawa, A Inui, T Kaga, H Yuzuriha, T Nagata, N Ueno, S Makino, M Fujimiya, A Niijima, M A Fujino,[...]. Gastroenterology 2001
920
10

Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans.
H Ariyasu, K Takaya, T Tagami, Y Ogawa, K Hosoda, T Akamizu, M Suda, T Koh, K Natsui, S Toyooka,[...]. J Clin Endocrinol Metab 2001
945
10

Absence of ghrelin protects against early-onset obesity.
Katherine E Wortley, Juan-Pablo del Rincon, Jane D Murray, Karen Garcia, Keiji Iida, Michael O Thorner, Mark W Sleeman. J Clin Invest 2005
285
10

Ablation of ghrelin receptor reduces adiposity and improves insulin sensitivity during aging by regulating fat metabolism in white and brown adipose tissues.
Ligen Lin, Pradip K Saha, Xiaojun Ma, Iyabo O Henshaw, Longjiang Shao, Benny H J Chang, Eric D Buras, Qiang Tong, Lawrence Chan, Owen P McGuinness,[...]. Aging Cell 2011
129
10

Ghrelin secretion stimulated by {beta}1-adrenergic receptors in cultured ghrelinoma cells and in fasted mice.
Tong-Jin Zhao, Ichiro Sakata, Robert Lin Li, Guosheng Liang, James A Richardson, Michael S Brown, Joseph L Goldstein, Jeffrey M Zigman. Proc Natl Acad Sci U S A 2010
148
10

Ghrelin stimulates gastric acid secretion and motility in rats.
Y Masuda, T Tanaka, N Inomata, N Ohnuma, S Tanaka, Z Itoh, H Hosoda, M Kojima, K Kangawa. Biochem Biophys Res Commun 2000
686
10


Induced ablation of ghrelin cells in adult mice does not decrease food intake, body weight, or response to high-fat diet.
Matthew R McFarlane, Michael S Brown, Joseph L Goldstein, Tong-Jin Zhao. Cell Metab 2014
115
9

Ghrelin increases food intake in obese as well as lean subjects.
M R Druce, A M Wren, A J Park, J E Milton, M Patterson, G Frost, M A Ghatei, C Small, S R Bloom. Int J Obes (Lond) 2005
267
9

Mice lacking ghrelin receptors resist the development of diet-induced obesity.
Jeffrey M Zigman, Yoshihide Nakano, Roberto Coppari, Nina Balthasar, Jacob N Marcus, Charlotte E Lee, Juli E Jones, Amy E Deysher, Amanda R Waxman, Ryan D White,[...]. J Clin Invest 2005
462
9

Blockade of pancreatic islet-derived ghrelin enhances insulin secretion to prevent high-fat diet-induced glucose intolerance.
Katsuya Dezaki, Hideyuki Sone, Masaru Koizumi, Masanori Nakata, Masafumi Kakei, Hideo Nagai, Hiroshi Hosoda, Kenji Kangawa, Toshihiko Yada. Diabetes 2006
184
9

Ghrelin action in the brain controls adipocyte metabolism.
Claudia Theander-Carrillo, Petra Wiedmer, Philippe Cettour-Rose, Ruben Nogueiras, Diego Perez-Tilve, Paul Pfluger, Tamara R Castaneda, Patrick Muzzin, Annette Schürmann, Ildiko Szanto,[...]. J Clin Invest 2006
343
9

GOAT links dietary lipids with the endocrine control of energy balance.
Henriette Kirchner, Jesus A Gutierrez, Patricia J Solenberg, Paul T Pfluger, Traci A Czyzyk, Jill A Willency, Annette Schürmann, Hans-Georg Joost, Ronald J Jandacek, John E Hale,[...]. Nat Med 2009
306
9

The influence of insulin on circulating ghrelin.
Daniel E Flanagan, Mark L Evans, Teresa P Monsod, Frances Rife, Rubina A Heptulla, William V Tamborlane, Robert S Sherwin. Am J Physiol Endocrinol Metab 2003
299
9

Glucose-mediated control of ghrelin release from primary cultures of gastric mucosal cells.
Ichiro Sakata, Won-Mee Park, Angela K Walker, Paul K Piper, Jen-Chieh Chuang, Sherri Osborne-Lawrence, Jeffrey M Zigman. Am J Physiol Endocrinol Metab 2012
79
11

Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor.
Brad P Barnett, Yousang Hwang, Martin S Taylor, Henriette Kirchner, Paul T Pfluger, Vincent Bernard, Yu-yi Lin, Erin M Bowers, Chandrani Mukherjee, Woo-Jin Song,[...]. Science 2010
201
9

Food fails to suppress ghrelin levels in obese humans.
P J English, M A Ghatei, I A Malik, S R Bloom, J P H Wilding. J Clin Endocrinol Metab 2002
381
9

Profound hypoglycemia in starved, ghrelin-deficient mice is caused by decreased gluconeogenesis and reversed by lactate or fatty acids.
Robert Lin Li, Daniel P Sherbet, Benjamin L Elsbernd, Joseph L Goldstein, Michael S Brown, Tong-Jin Zhao. J Biol Chem 2012
86
9

Reduced autophagy in livers of fasted, fat-depleted, ghrelin-deficient mice: reversal by growth hormone.
Yuanyuan Zhang, Fei Fang, Joseph L Goldstein, Michael S Brown, Tong-Jin Zhao. Proc Natl Acad Sci U S A 2015
59
13


Hindbrain ghrelin receptor signaling is sufficient to maintain fasting glucose.
Michael M Scott, Mario Perello, Jen-Chieh Chuang, Ichiro Sakata, Laurent Gautron, Charlotte E Lee, Danielle Lauzon, Joel K Elmquist, Jeffrey M Zigman. PLoS One 2012
47
17

Deletion of ghrelin impairs neither growth nor appetite.
Yuxiang Sun, Saira Ahmed, Roy G Smith. Mol Cell Biol 2003
486
8


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.