A citation-based method for searching scientific literature

Brinda Ravikumar, Rainer Duden, David C Rubinsztein. Hum Mol Genet 2002
Times Cited: 828







List of co-cited articles
2268 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.
Brinda Ravikumar, Coralie Vacher, Zdenek Berger, Janet E Davies, Shouqing Luo, Lourdes G Oroz, Francesco Scaravilli, Douglas F Easton, Rainer Duden, Cahir J O'Kane,[...]. Nat Genet 2004
36

Loss of autophagy in the central nervous system causes neurodegeneration in mice.
Masaaki Komatsu, Satoshi Waguri, Tomoki Chiba, Shigeo Murata, Jun-ichi Iwata, Isei Tanida, Takashi Ueno, Masato Koike, Yasuo Uchiyama, Eiki Kominami,[...]. Nature 2006
31

Alpha-Synuclein is degraded by both autophagy and the proteasome.
Julie L Webb, Brinda Ravikumar, Jane Atkins, Jeremy N Skepper, David C Rubinsztein. J Biol Chem 2003
28

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice.
Taichi Hara, Kenji Nakamura, Makoto Matsui, Akitsugu Yamamoto, Yohko Nakahara, Rika Suzuki-Migishima, Minesuke Yokoyama, Kenji Mishima, Ichiro Saito, Hideyuki Okano,[...]. Nature 2006
28

Rapamycin alleviates toxicity of different aggregate-prone proteins.
Zdenek Berger, Brinda Ravikumar, Fiona M Menzies, Lourdes Garcia Oroz, Benjamin R Underwood, Menelas N Pangalos, Ina Schmitt, Ullrich Wullner, Bernd O Evert, Cahir J O'Kane,[...]. Hum Mol Genet 2006
489
23


Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.
Marta Martinez-Vicente, Zsolt Talloczy, Esther Wong, Guomei Tang, Hiroshi Koga, Susmita Kaushik, Rosa de Vries, Esperanza Arias, Spike Harris, David Sulzer,[...]. Nat Neurosci 2010
531
20

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities.
Fiona M Menzies, Angeleen Fleming, Andrea Caricasole, Carla F Bento, Stephen P Andrews, Avraham Ashkenazi, Jens Füllgrabe, Anne Jackson, Maria Jimenez Sanchez, Cansu Karabiyik,[...]. Neuron 2017
500
19

Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease.
Patricia Spilman, Natalia Podlutskaya, Matthew J Hart, Jayanta Debnath, Olivia Gorostiza, Dale Bredesen, Arlan Richardson, Randy Strong, Veronica Galvan. PLoS One 2010
657
19

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy.
Serhiy Pankiv, Terje Høyvarde Clausen, Trond Lamark, Andreas Brech, Jack-Ansgar Bruun, Heidi Outzen, Aud Øvervatn, Geir Bjørkøy, Terje Johansen. J Biol Chem 2007
17

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway.
Andrea Williams, Sovan Sarkar, Paul Cuddon, Evangelia K Ttofi, Shinji Saiki, Farah H Siddiqi, Luca Jahreiss, Angeleen Fleming, Dean Pask, Paul Goldsmith,[...]. Nat Chem Biol 2008
579
16

Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.
Ralph A Nixon, Jerzy Wegiel, Asok Kumar, Wai Haung Yu, Corrinne Peterhoff, Anne Cataldo, Ana Maria Cuervo. J Neuropathol Exp Neurol 2005
984
16

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
16

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death.
Geir Bjørkøy, Trond Lamark, Andreas Brech, Heidi Outzen, Maria Perander, Aud Overvatn, Harald Stenmark, Terje Johansen. J Cell Biol 2005
15

Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease.
Barry Boland, Asok Kumar, Sooyeon Lee, Frances M Platt, Jerzy Wegiel, W Haung Yu, Ralph A Nixon. J Neurosci 2008
745
15

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy.
Ana Maria Cuervo, Leonidas Stefanis, Ross Fredenburg, Peter T Lansbury, David Sulzer. Science 2004
15


Potential function for the Huntingtin protein as a scaffold for selective autophagy.
Joseph Ochaba, Tamás Lukacsovich, George Csikos, Shuqiu Zheng, Julia Margulis, Lisa Salazar, Kai Mao, Alice L Lau, Sylvia Y Yeung, Sandrine Humbert,[...]. Proc Natl Acad Sci U S A 2014
158
14

Huntingtin functions as a scaffold for selective macroautophagy.
Yan-Ning Rui, Zhen Xu, Bindi Patel, Zhihua Chen, Dongsheng Chen, Antonio Tito, Gabriela David, Yamin Sun, Erin F Stimming, Hugo J Bellen,[...]. Nat Cell Biol 2015
236
14

Polyglutamine tracts regulate beclin 1-dependent autophagy.
Avraham Ashkenazi, Carla F Bento, Thomas Ricketts, Mariella Vicinanza, Farah Siddiqi, Mariana Pavel, Ferdinando Squitieri, Maarten C Hardenberg, Sara Imarisio, Fiona M Menzies,[...]. Nature 2017
181
14

TFEB links autophagy to lysosomal biogenesis.
Carmine Settembre, Chiara Di Malta, Vinicia Assunta Polito, Moises Garcia Arencibia, Francesco Vetrini, Serkan Erdin, Serpil Uckac Erdin, Tuong Huynh, Diego Medina, Pasqualina Colella,[...]. Science 2011
13

α-Synuclein impairs macroautophagy: implications for Parkinson's disease.
Ashley R Winslow, Chien-Wen Chen, Silvia Corrochano, Abraham Acevedo-Arozena, David E Gordon, Andrew A Peden, Maike Lichtenberg, Fiona M Menzies, Brinda Ravikumar, Sara Imarisio,[...]. J Cell Biol 2010
508
13

Autophagy fights disease through cellular self-digestion.
Noboru Mizushima, Beth Levine, Ana Maria Cuervo, Daniel J Klionsky. Nature 2008
13

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
12

Lithium induces autophagy by inhibiting inositol monophosphatase.
Sovan Sarkar, R Andres Floto, Zdenek Berger, Sara Imarisio, Axelle Cordenier, Matthieu Pasco, Lynnette J Cook, David C Rubinsztein. J Cell Biol 2005
705
12

The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy.
Maria Filimonenko, Pauline Isakson, Kim D Finley, Monique Anderson, Hyun Jeong, Thomas J Melia, Bryan J Bartlett, Katherine M Myers, Hanne C G Birkeland, Trond Lamark,[...]. Mol Cell 2010
299
12


Autophagy in the pathogenesis of disease.
Beth Levine, Guido Kroemer. Cell 2008
12

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.
Ryan C Russell, Ye Tian, Haixin Yuan, Hyun Woo Park, Yu-Yun Chang, Joungmok Kim, Haerin Kim, Thomas P Neufeld, Andrew Dillin, Kun-Liang Guan. Nat Cell Biol 2013
882
12

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice.
Fiona Pickford, Eliezer Masliah, Markus Britschgi, Kurt Lucin, Ramya Narasimhan, Philipp A Jaeger, Scott Small, Brian Spencer, Edward Rockenstein, Beth Levine,[...]. J Clin Invest 2008
749
12

Autophagy: renovation of cells and tissues.
Noboru Mizushima, Masaaki Komatsu. Cell 2011
12

Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1.
Mamoru Shibata, Tao Lu, Tsuyoshi Furuya, Alexei Degterev, Noboru Mizushima, Tamotsu Yoshimori, Marcy MacDonald, Bruce Yankner, Junying Yuan. J Biol Chem 2006
339
12

PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function.
Taiji Tsunemi, Travis D Ashe, Bradley E Morrison, Kathryn R Soriano, Jonathan Au, Ruben A Vázquez Roque, Eduardo R Lazarowski, Vincent A Damian, Eliezer Masliah, Albert R La Spada. Sci Transl Med 2012
294
11

Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.
Sovan Sarkar, Janet E Davies, Zebo Huang, Alan Tunnacliffe, David C Rubinsztein. J Biol Chem 2007
751
11

Autophagy genes are essential for dauer development and life-span extension in C. elegans.
Alicia Meléndez, Zsolt Tallóczy, Matthew Seaman, Eeva-Liisa Eskelinen, David H Hall, Beth Levine. Science 2003
919
11

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing.
Y Kabeya, N Mizushima, T Ueno, A Yamamoto, T Kirisako, T Noda, E Kominami, Y Ohsumi, T Yoshimori. EMBO J 2000
11

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Daniel J Klionsky, Kotb Abdelmohsen, Akihisa Abe, Md Joynal Abedin, Hagai Abeliovich, Abraham Acevedo Arozena, Hiroaki Adachi, Christopher M Adams, Peter D Adams, Khosrow Adeli,[...]. Autophagy 2016
11

Autophagy in Huntington disease and huntingtin in autophagy.
Dale D O Martin, Safia Ladha, Dagmar E Ehrnhoefer, Michael R Hayden. Trends Neurosci 2015
170
11

Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models.
Sami J Barmada, Andrea Serio, Arpana Arjun, Bilada Bilican, Aaron Daub, D Michael Ando, Andrey Tsvetkov, Michael Pleiss, Xingli Li, Daniel Peisach,[...]. Nat Chem Biol 2014
268
11

TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity.
Mickael Decressac, Bengt Mattsson, Pia Weikop, Martin Lundblad, Johan Jakobsson, Anders Björklund. Proc Natl Acad Sci U S A 2013
420
11

Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases.
Brian Spencer, Rewati Potkar, Margarita Trejo, Edward Rockenstein, Christina Patrick, Ryan Gindi, Anthony Adame, Tony Wyss-Coray, Eliezer Masliah. J Neurosci 2009
427
11

Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations.
Ju-Hyun Lee, W Haung Yu, Asok Kumar, Sooyeon Lee, Panaiyur S Mohan, Corrinne M Peterhoff, Devin M Wolfe, Marta Martinez-Vicente, Ashish C Massey, Guy Sovak,[...]. Cell 2010
735
11

Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease.
W Haung Yu, Ana Maria Cuervo, Asok Kumar, Corrinne M Peterhoff, Stephen D Schmidt, Ju-Hyun Lee, Panaiyur S Mohan, Marc Mercken, Mark R Farmery, Lars O Tjernberg,[...]. J Cell Biol 2005
695
11

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
10

Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates.
Jelena Korac, Veronique Schaeffer, Igor Kovacevic, Albrecht M Clement, Benno Jungblut, Christian Behl, Janos Terzic, Ivan Dikic. J Cell Sci 2013
204
10

Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation.
Atsushi Iwata, John C Christianson, Mirella Bucci, Lisa M Ellerby, Nobuyuki Nukina, Lysia S Forno, Ron R Kopito. Proc Natl Acad Sci U S A 2005
246
10

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin.
Atsushi Iwata, Brigit E Riley, Jennifer A Johnston, Ron R Kopito. J Biol Chem 2005
565
10


Autophagy and aging.
David C Rubinsztein, Guillermo Mariño, Guido Kroemer. Cell 2011
10

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS.
Udai Bhan Pandey, Zhiping Nie, Yakup Batlevi, Brett A McCray, Gillian P Ritson, Natalia B Nedelsky, Stephanie L Schwartz, Nicholas A DiProspero, Melanie A Knight, Oren Schuldiner,[...]. Nature 2007
902
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.