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Times Cited: 265
Times Cited: 265
Times Cited
Times Co-cited
Similarity
Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
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HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia.
Jung-whan Kim, Irina Tchernyshyov, Gregg L Semenza, Chi V Dang. Cell Metab 2006
Jung-whan Kim, Irina Tchernyshyov, Gregg L Semenza, Chi V Dang. Cell Metab 2006
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mtDNA mutations increase tumorigenicity in prostate cancer.
John A Petros, Amanda K Baumann, Eduardo Ruiz-Pesini, Mahul B Amin, Carrie Qi Sun, John Hall, SoDug Lim, Muta M Issa, W Dana Flanders, Seyed H Hosseini,[...]. Proc Natl Acad Sci U S A 2005
John A Petros, Amanda K Baumann, Eduardo Ruiz-Pesini, Mahul B Amin, Carrie Qi Sun, John Hall, SoDug Lim, Muta M Issa, W Dana Flanders, Seyed H Hosseini,[...]. Proc Natl Acad Sci U S A 2005
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Mitochondrial DNA mutations and mitochondrial DNA depletion in gastric cancer.
Chew-Wun Wu, Pen-Hui Yin, Wen-Yi Hung, Anna Fen-Yau Li, Shu-Hui Li, Chin-Wen Chi, Yau-Huei Wei, Hsin-Chen Lee. Genes Chromosomes Cancer 2005
Chew-Wun Wu, Pen-Hui Yin, Wen-Yi Hung, Anna Fen-Yau Li, Shu-Hui Li, Chin-Wen Chi, Yau-Huei Wei, Hsin-Chen Lee. Genes Chromosomes Cancer 2005
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Decrease of mitochondrial DNA content and energy metabolism in renal cell carcinoma.
David Meierhofer, Johannes A Mayr, Ulrike Foetschl, Alexandra Berger, Klaus Fink, Nikolaus Schmeller, Gerhard W Hacker, Cornelia Hauser-Kronberger, Barbara Kofler, Wolfgang Sperl. Carcinogenesis 2004
David Meierhofer, Johannes A Mayr, Ulrike Foetschl, Alexandra Berger, Klaus Fink, Nikolaus Schmeller, Gerhard W Hacker, Cornelia Hauser-Kronberger, Barbara Kofler, Wolfgang Sperl. Carcinogenesis 2004
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PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis.
Valerie S LeBleu, Joyce T O'Connell, Karina N Gonzalez Herrera, Harriet Wikman, Klaus Pantel, Marcia C Haigis, Fernanda Machado de Carvalho, Aline Damascena, Ludmilla Thome Domingos Chinen, Rafael M Rocha,[...]. Nat Cell Biol 2014
Valerie S LeBleu, Joyce T O'Connell, Karina N Gonzalez Herrera, Harriet Wikman, Klaus Pantel, Marcia C Haigis, Fernanda Machado de Carvalho, Aline Damascena, Ludmilla Thome Domingos Chinen, Rafael M Rocha,[...]. Nat Cell Biol 2014
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HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption.
Ioanna Papandreou, Rob A Cairns, Lucrezia Fontana, Ai Lin Lim, Nicholas C Denko. Cell Metab 2006
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ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis.
Kaori Ishikawa, Keizo Takenaga, Miho Akimoto, Nobuko Koshikawa, Aya Yamaguchi, Hirotake Imanishi, Kazuto Nakada, Yoshio Honma, Jun-Ichi Hayashi. Science 2008
Kaori Ishikawa, Keizo Takenaga, Miho Akimoto, Nobuko Koshikawa, Aya Yamaguchi, Hirotake Imanishi, Kazuto Nakada, Yoshio Honma, Jun-Ichi Hayashi. Science 2008
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Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
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Association of decreased mitochondrial DNA content with ovarian cancer progression.
Y Wang, V W S Liu, W C Xue, A N Y Cheung, H Y S Ngan. Br J Cancer 2006
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Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer.
Ling-Ming Tseng, Pen-Hui Yin, Chin-Wen Chi, Chih-Yi Hsu, Chew-Wun Wu, Liang-Ming Lee, Yau-Huei Wei, Hsin-Chen Lee. Genes Chromosomes Cancer 2006
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Why do cancers have high aerobic glycolysis?
Robert A Gatenby, Robert J Gillies. Nat Rev Cancer 2004
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Impaired OXPHOS complex III in breast cancer.
Kjerstin M Owens, Mariola Kulawiec, Mohamad Mokhtar Desouki, Ayyasamy Vanniarajan, Keshav K Singh. PLoS One 2011
Kjerstin M Owens, Mariola Kulawiec, Mohamad Mokhtar Desouki, Ayyasamy Vanniarajan, Keshav K Singh. PLoS One 2011
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HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity.
Huafeng Zhang, Ping Gao, Ryo Fukuda, Ganesh Kumar, Balaji Krishnamachary, Karen I Zeller, Chi V Dang, Gregg L Semenza. Cancer Cell 2007
Huafeng Zhang, Ping Gao, Ryo Fukuda, Ganesh Kumar, Balaji Krishnamachary, Karen I Zeller, Chi V Dang, Gregg L Semenza. Cancer Cell 2007
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Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma.
Edward L LaGory, Colleen Wu, Cullen M Taniguchi, Chien-Kuang Cornelia Ding, Jen-Tsan Chi, Rie von Eyben, David A Scott, Adam D Richardson, Amato J Giaccia. Cell Rep 2015
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Mitochondrial genome instability and mtDNA depletion in human cancers.
Hsin-Chen Lee, Pen-Hui Yin, Jin-Ching Lin, Cheng-Chung Wu, Chih-Yi Chen, Chew-Wun Wu, Chin-Wen Chi, Tseng-Nip Tam, Yau-Huei Wei. Ann N Y Acad Sci 2005
Hsin-Chen Lee, Pen-Hui Yin, Jin-Ching Lin, Cheng-Chung Wu, Chih-Yi Chen, Chew-Wun Wu, Chin-Wen Chi, Tseng-Nip Tam, Yau-Huei Wei. Ann N Y Acad Sci 2005
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Mitochondrial complex I is deficient in renal oncocytomas.
Helene Simonnet, Jocelyne Demont, Kathy Pfeiffer, Leila Guenaneche, Raymonde Bouvier, Ulrich Brandt, Hermann Schagger, Catherine Godinot. Carcinogenesis 2003
Helene Simonnet, Jocelyne Demont, Kathy Pfeiffer, Leila Guenaneche, Raymonde Bouvier, Ulrich Brandt, Hermann Schagger, Catherine Godinot. Carcinogenesis 2003
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Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III.
Elena Bonora, Anna Maria Porcelli, Giuseppe Gasparre, Annalisa Biondi, Anna Ghelli, Valerio Carelli, Alessandra Baracca, Giovanni Tallini, Andrea Martinuzzi, Giorgio Lenaz,[...]. Cancer Res 2006
Elena Bonora, Anna Maria Porcelli, Giuseppe Gasparre, Annalisa Biondi, Anna Ghelli, Valerio Carelli, Alessandra Baracca, Giovanni Tallini, Andrea Martinuzzi, Giorgio Lenaz,[...]. Cancer Res 2006
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p53 regulates mitochondrial respiration.
Satoaki Matoba, Ju-Gyeong Kang, Willmar D Patino, Andrew Wragg, Manfred Boehm, Oksana Gavrilova, Paula J Hurley, Fred Bunz, Paul M Hwang. Science 2006
Satoaki Matoba, Ju-Gyeong Kang, Willmar D Patino, Andrew Wragg, Manfred Boehm, Oksana Gavrilova, Paula J Hurley, Fred Bunz, Paul M Hwang. Science 2006
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Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma.
Hsin-Chen Lee, Shu-Hui Li, Jin-Ching Lin, Cheng-Chung Wu, Dah-Cherg Yeh, Yau-Huei Wei. Mutat Res 2004
Hsin-Chen Lee, Shu-Hui Li, Jin-Ching Lin, Cheng-Chung Wu, Dah-Cherg Yeh, Yau-Huei Wei. Mutat Res 2004
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Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia.
Rui-Hua Xu, Helene Pelicano, Yan Zhou, Jennifer S Carew, Li Feng, Kapil N Bhalla, Michael J Keating, Peng Huang. Cancer Res 2005
Rui-Hua Xu, Helene Pelicano, Yan Zhou, Jennifer S Carew, Li Feng, Kapil N Bhalla, Michael J Keating, Peng Huang. Cancer Res 2005
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Reduced mitochondrial DNA copy number is correlated with tumor progression and prognosis in Chinese breast cancer patients.
Man Yu, Yunli Zhou, Yurong Shi, Liansheng Ning, Yi Yang, Xiyin Wei, Ning Zhang, Xishan Hao, Ruifang Niu. IUBMB Life 2007
Man Yu, Yunli Zhou, Yurong Shi, Liansheng Ning, Yi Yang, Xiyin Wei, Ning Zhang, Xishan Hao, Ruifang Niu. IUBMB Life 2007
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Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma.
Jinliang Xing, Meng Chen, Christopher G Wood, Jie Lin, Margaret R Spitz, Jianzhong Ma, Christopher I Amos, Peter G Shields, Neal L Benowitz, Jian Gu,[...]. J Natl Cancer Inst 2008
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Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy.
Chin-Chih Lin, Tsung-Lin Cheng, Wen-Hui Tsai, Hui-Ju Tsai, Keng-Hsun Hu, Hao-Chun Chang, Chin-Wei Yeh, Ying-Chou Chen, Ching-Chun Liao, Wen-Tsan Chang. Sci Rep 2012
Chin-Chih Lin, Tsung-Lin Cheng, Wen-Hui Tsai, Hui-Ju Tsai, Keng-Hsun Hu, Hao-Chun Chang, Chin-Wei Yeh, Ying-Chou Chen, Ching-Chun Liao, Wen-Tsan Chang. Sci Rep 2012
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HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells.
Ryo Fukuda, Huafeng Zhang, Jung-whan Kim, Larissa Shimoda, Chi V Dang, Gregg L Semenza. Cell 2007
Ryo Fukuda, Huafeng Zhang, Jung-whan Kim, Larissa Shimoda, Chi V Dang, Gregg L Semenza. Cell 2007
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Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer.
Ian P M Tomlinson, N Afrina Alam, Andrew J Rowan, Ella Barclay, Emma E M Jaeger, David Kelsell, Irene Leigh, Patricia Gorman, Hanan Lamlum, Shamima Rahman,[...]. Nat Genet 2002
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The bioenergetic signature of cancer: a marker of tumor progression.
José M Cuezva, Maryla Krajewska, Miguel López de Heredia, Stanislaw Krajewski, Gema Santamaría, Hoguen Kim, Juan M Zapata, Hiroyuki Marusawa, Margarita Chamorro, John C Reed. Cancer Res 2002
José M Cuezva, Maryla Krajewska, Miguel López de Heredia, Stanislaw Krajewski, Gema Santamaría, Hoguen Kim, Juan M Zapata, Hiroyuki Marusawa, Margarita Chamorro, John C Reed. Cancer Res 2002
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Otto Warburg's contributions to current concepts of cancer metabolism.
Willem H Koppenol, Patricia L Bounds, Chi V Dang. Nat Rev Cancer 2011
Willem H Koppenol, Patricia L Bounds, Chi V Dang. Nat Rev Cancer 2011
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Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue.
Diana Whitaker-Menezes, Ubaldo E Martinez-Outschoorn, Neal Flomenberg, Ruth C Birbe, Agnieszka K Witkiewicz, Anthony Howell, Stephanos Pavlides, Aristotelis Tsirigos, Adam Ertel, Richard G Pestell,[...]. Cell Cycle 2011
Diana Whitaker-Menezes, Ubaldo E Martinez-Outschoorn, Neal Flomenberg, Ruth C Birbe, Agnieszka K Witkiewicz, Anthony Howell, Stephanos Pavlides, Aristotelis Tsirigos, Adam Ertel, Richard G Pestell,[...]. Cell Cycle 2011
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The role of mitochondrial DNA alterations in esophageal squamous cell carcinomas.
Chen-Sung Lin, Shi-Chuan Chang, Liang-Shun Wang, Teh-Ying Chou, Wen-Hu Hsu, Yu-Chung Wu, Yau-Huei Wei. J Thorac Cardiovasc Surg 2010
Chen-Sung Lin, Shi-Chuan Chang, Liang-Shun Wang, Teh-Ying Chou, Wen-Hu Hsu, Yu-Chung Wu, Yau-Huei Wei. J Thorac Cardiovasc Surg 2010
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Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability.
David R Wise, Patrick S Ward, Jessica E S Shay, Justin R Cross, Joshua J Gruber, Uma M Sachdeva, Jesse M Platt, Raymond G DeMatteo, M Celeste Simon, Craig B Thompson. Proc Natl Acad Sci U S A 2011
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Alteration of the bioenergetic phenotype of mitochondria is a hallmark of breast, gastric, lung and oesophageal cancer.
Antonio Isidoro, Marta Martínez, Pedro L Fernández, Alvaro D Ortega, Gema Santamaría, Margarita Chamorro, John C Reed, José M Cuezva. Biochem J 2004
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Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.
Wei Xu, Hui Yang, Ying Liu, Ying Yang, Ping Wang, Se-Hee Kim, Shinsuke Ito, Chen Yang, Pu Wang, Meng-Tao Xiao,[...]. Cancer Cell 2011
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Enhanced citrate synthase activity in human pancreatic cancer.
Beata Schlichtholz, Jacek Turyn, Elzbieta Goyke, Maciej Biernacki, Kazimierz Jaskiewicz, Zbigniew Sledzinski, Julian Swierczynski. Pancreas 2005
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Mitochondria and human cancer.
Josephine S Modica-Napolitano, Mariola Kulawiec, Keshav K Singh. Curr Mol Med 2007
Josephine S Modica-Napolitano, Mariola Kulawiec, Keshav K Singh. Curr Mol Med 2007
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Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase.
Mary A Selak, Sean M Armour, Elaine D MacKenzie, Houda Boulahbel, David G Watson, Kyle D Mansfield, Yi Pan, M Celeste Simon, Craig B Thompson, Eyal Gottlieb. Cancer Cell 2005
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The genetic basis of kidney cancer: a metabolic disease.
W Marston Linehan, Ramaprasad Srinivasan, Laura S Schmidt. Nat Rev Urol 2010
W Marston Linehan, Ramaprasad Srinivasan, Laura S Schmidt. Nat Rev Urol 2010
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Lack of complex I is associated with oncocytic thyroid tumours.
F A Zimmermann, J A Mayr, D Neureiter, R Feichtinger, B Alinger, N D Jones, W Eder, W Sperl, B Kofler. Br J Cancer 2009
F A Zimmermann, J A Mayr, D Neureiter, R Feichtinger, B Alinger, N D Jones, W Eder, W Sperl, B Kofler. Br J Cancer 2009
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Metabolic reprogramming: a cancer hallmark even warburg did not anticipate.
Patrick S Ward, Craig B Thompson. Cancer Cell 2012
Patrick S Ward, Craig B Thompson. Cancer Cell 2012
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Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA.
An S Tan, James W Baty, Lan-Feng Dong, Ayenachew Bezawork-Geleta, Berwini Endaya, Jacob Goodwin, Martina Bajzikova, Jaromira Kovarova, Martin Peterka, Bing Yan,[...]. Cell Metab 2015
An S Tan, James W Baty, Lan-Feng Dong, Ayenachew Bezawork-Geleta, Berwini Endaya, Jacob Goodwin, Martina Bajzikova, Jaromira Kovarova, Martin Peterka, Bing Yan,[...]. Cell Metab 2015
6
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.