A citation-based method for searching scientific literature

Sandrine Humbert, Elzbieta A Bryson, Fabrice P Cordelières, Nathan C Connors, Sandeep R Datta, Steven Finkbeiner, Michael E Greenberg, Frédéric Saudou. Dev Cell 2002
Times Cited: 370







List of co-cited articles
1866 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



The Biology of Huntingtin.
Frédéric Saudou, Sandrine Humbert. Neuron 2016
436
23

Akt is altered in an animal model of Huntington's disease and in patients.
Emilie Colin, Etienne Régulier, Valérie Perrin, Alexandra Dürr, Alexis Brice, Patrick Aebischer, Nicole Déglon, Sandrine Humbert, Frédéric Saudou. Eur J Neurosci 2005
132
22

Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons.
Emilie Colin, Diana Zala, Géraldine Liot, Hélène Rangone, Maria Borrell-Pagès, Xiao-Jiang Li, Frédéric Saudou, Sandrine Humbert. EMBO J 2008
240
19

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
810
18

Phosphorylation of threonine 3: implications for Huntingtin aggregation and neurotoxicity.
Charity T Aiken, Joan S Steffan, Cortnie M Guerrero, Hasan Khashwji, Tamas Lukacsovich, Danielle Simmons, Judy M Purcell, Kimia Menhaji, Ya-Zhen Zhu, Kim Green,[...]. J Biol Chem 2009
116
18

Acetylation targets mutant huntingtin to autophagosomes for degradation.
Hyunkyung Jeong, Florian Then, Thomas J Melia, Joseph R Mazzulli, Libin Cui, Jeffrey N Savas, Cindy Voisine, Paolo Paganetti, Naoko Tanese, Anne C Hart,[...]. Cell 2009
281
17

SUMO modification of Huntingtin and Huntington's disease pathology.
Joan S Steffan, Namita Agrawal, Judit Pallos, Erica Rockabrand, Lloyd C Trotman, Natalia Slepko, Katalin Illes, Tamas Lukacsovich, Ya-Zhen Zhu, Elena Cattaneo,[...]. Science 2004
510
17

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome.
Leslie Michels Thompson, Charity T Aiken, Linda S Kaltenbach, Namita Agrawal, Katalin Illes, Ali Khoshnan, Marta Martinez-Vincente, Montserrat Arrasate, Jacqueline Gire O'Rourke, Hasan Khashwji,[...]. J Cell Biol 2009
263
17

The serum- and glucocorticoid-induced kinase SGK inhibits mutant huntingtin-induced toxicity by phosphorylating serine 421 of huntingtin.
Hélène Rangone, Ghislaine Poizat, Juan Troncoso, Christopher A Ross, Marcy E MacDonald, Frédéric Saudou, Sandrine Humbert. Eur J Neurosci 2004
108
16

Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases: implications for mutant huntingtin toxicity.
Shouqing Luo, Coralie Vacher, Janet E Davies, David C Rubinsztein. J Cell Biol 2005
136
16

Inhibition of calcineurin by FK506 protects against polyglutamine-huntingtin toxicity through an increase of huntingtin phosphorylation at S421.
Raúl Pardo, Emilie Colin, Etienne Régulier, Patrick Aebischer, Nicole Déglon, Sandrine Humbert, Frédéric Saudou. J Neurosci 2006
100
16

Huntingtin phosphorylation sites mapped by mass spectrometry. Modulation of cleavage and toxicity.
Birgit Schilling, Juliette Gafni, Cameron Torcassi, Xin Cong, Richard H Row, Michelle A LaFevre-Bernt, Michael P Cusack, Tamara Ratovitski, Ricky Hirschhorn, Christopher A Ross,[...]. J Biol Chem 2006
96
16

Serine 421 regulates mutant huntingtin toxicity and clearance in mice.
Ian H Kratter, Hengameh Zahed, Alice Lau, Andrey S Tsvetkov, Aaron C Daub, Kurt F Weiberth, Xiaofeng Gu, Frédéric Saudou, Sandrine Humbert, X William Yang,[...]. J Clin Invest 2016
33
48

Activation of IGF-1 and insulin signaling pathways ameliorate mitochondrial function and energy metabolism in Huntington's Disease human lymphoblasts.
Luana Naia, I Luísa Ferreira, Teresa Cunha-Oliveira, Ana I Duarte, Márcio Ribeiro, Tatiana R Rosenstock, Mário N Laço, Maria J Ribeiro, Catarina R Oliveira, Frédéric Saudou,[...]. Mol Neurobiol 2015
55
27

Palmitoylation of huntingtin by HIP14 is essential for its trafficking and function.
Anat Yanai, Kun Huang, Rujun Kang, Roshni R Singaraja, Pamela Arstikaitis, Lu Gan, Paul C Orban, Asher Mullard, Catherine M Cowan, Lynn A Raymond,[...]. Nat Neurosci 2006
213
15

Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice.
Xiaofeng Gu, Erin R Greiner, Rakesh Mishra, Ravindra Kodali, Alex Osmand, Steven Finkbeiner, Joan S Steffan, Leslie Michels Thompson, Ronald Wetzel, X William Yang. Neuron 2009
230
15


Huntingtin phosphorylation on serine 421 is significantly reduced in the striatum and by polyglutamine expansion in vivo.
Simon C Warby, Edmond Y Chan, Martina Metzler, Lu Gan, Roshni R Singaraja, Susan F Crocker, Harold A Robertson, Michael R Hayden. Hum Mol Genet 2005
99
14


IGF-1 intranasal administration rescues Huntington's disease phenotypes in YAC128 mice.
Carla Lopes, Márcio Ribeiro, Ana I Duarte, Sandrine Humbert, Frederic Saudou, Luís Pereira de Almeida, Michael Hayden, A Cristina Rego. Mol Neurobiol 2014
56
23

Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin.
Rona K Graham, Yu Deng, Elizabeth J Slow, Brendan Haigh, Nagat Bissada, Ge Lu, Jacqueline Pearson, Jacqueline Shehadeh, Lisa Bertram, Zoe Murphy,[...]. Cell 2006
479
13

Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons.
Diana Zala, Emilie Colin, Hélène Rangone, Géraldine Liot, Sandrine Humbert, Frédéric Saudou. Hum Mol Genet 2008
112
13

Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
987
12

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
12

Network organization of the huntingtin proteomic interactome in mammalian brain.
Dyna I Shirasaki, Erin R Greiner, Ismael Al-Ramahi, Michelle Gray, Pinmanee Boontheung, Daniel H Geschwind, Juan Botas, Giovanni Coppola, Steve Horvath, Joseph A Loo,[...]. Neuron 2012
191
11

Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis.
Tamara Ratovitski, Ekaterine Chighladze, Nicolas Arbez, Tatiana Boronina, Shelley Herbrich, Robert N Cole, Christopher A Ross. Cell Cycle 2012
79
13

Huntingtin functions as a scaffold for selective macroautophagy.
Yan-Ning Rui, Zhen Xu, Bindi Patel, Zhihua Chen, Dongsheng Chen, Antonio Tito, Gabriela David, Yamin Sun, Erin F Stimming, Hugo J Bellen,[...]. Nat Cell Biol 2015
264
11


Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity.
Erin E Watkin, Nicolas Arbez, Elaine Waldron-Roby, Robert O'Meally, Tamara Ratovitski, Robert N Cole, Christopher A Ross. PLoS One 2014
33
30

Phosphorylation of huntingtin at Ser421 in YAC128 neurons is associated with protection of YAC128 neurons from NMDA-mediated excitotoxicity and is modulated by PP1 and PP2A.
Martina Metzler, Lu Gan, Gelareh Mazarei, Rona K Graham, Lili Liu, Nagat Bissada, Ge Lu, Blair R Leavitt, Michael R Hayden. J Neurosci 2010
66
15

Huntington disease.
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
682
10

Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats.
Tamara Ratovitski, Robert N O'Meally, Mali Jiang, Raghothama Chaerkady, Ekaterine Chighladze, Jacqueline C Stewart, Xiaofang Wang, Nicolas Arbez, Elaine Roby, Athanasios Alexandris,[...]. J Proteome Res 2017
30
33

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
J S Steffan, A Kazantsev, O Spasic-Boskovic, M Greenwald, Y Z Zhu, H Gohler, E E Wanker, G P Bates, D E Housman, L M Thompson. Proc Natl Acad Sci U S A 2000
799
9

Huntingtin interacting proteins are genetic modifiers of neurodegeneration.
Linda S Kaltenbach, Eliana Romero, Robert R Becklin, Rakesh Chettier, Russell Bell, Amit Phansalkar, Andrew Strand, Cameron Torcassi, Justin Savage, Anthony Hurlburt,[...]. PLoS Genet 2007
295
9

Huntington disease.
J P Vonsattel, M DiFiglia. J Neuropathol Exp Neurol 1998
9

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease.
C Zuccato, A Ciammola, D Rigamonti, B R Leavitt, D Goffredo, L Conti, M E MacDonald, R M Friedlander, V Silani, M R Hayden,[...]. Science 2001
947
9

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity.
Wenjun Song, Jin Chen, Alejandra Petrilli, Geraldine Liot, Eva Klinglmayr, Yue Zhou, Patrick Poquiz, Jonathan Tjong, Mahmoud A Pouladi, Michael R Hayden,[...]. Nat Med 2011
382
9

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes.
Chiara Zuccato, Marzia Tartari, Andrea Crotti, Donato Goffredo, Marta Valenza, Luciano Conti, Tiziana Cataudella, Blair R Leavitt, Michael R Hayden, Tõnis Timmusk,[...]. Nat Genet 2003
667
9

N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking.
Adam L Orr, Shihua Li, Chuan-En Wang, He Li, Jianjun Wang, Juan Rong, Xingshun Xu, Pier Giorgio Mastroberardino, J Timothy Greenamyre, Xiao-Jiang Li. J Neurosci 2008
294
9

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
9

Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity.
Randy Singh Atwal, Jianrun Xia, Deborah Pinchev, Jillian Taylor, Richard M Epand, Ray Truant. Hum Mol Genet 2007
269
9

Phosphorylation of huntingtin reduces the accumulation of its nuclear fragments.
Simon C Warby, Crystal N Doty, Rona K Graham, Jonathan Shively, Roshni R Singaraja, Michael R Hayden. Mol Cell Neurosci 2009
64
14

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
9


The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration.
David Heras-Sandoval, Jazmin M Pérez-Rojas, Jacqueline Hernández-Damián, José Pedraza-Chaverri. Cell Signal 2014
634
8


Mutant Huntingtin alters retrograde transport of TrkB receptors in striatal dendrites.
Géraldine Liot, Diana Zala, Patrick Pla, Guillaume Mottet, Matthieu Piel, Frédéric Saudou. J Neurosci 2013
109
8


Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.
Brinda Ravikumar, Coralie Vacher, Zdenek Berger, Janet E Davies, Shouqing Luo, Lourdes G Oroz, Francesco Scaravilli, Douglas F Easton, Rainer Duden, Cahir J O'Kane,[...]. Nat Genet 2004
8


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.