A citation-based method for searching scientific literature

Yong Ma, Alfrun Erkner, Ruoyu Gong, Shenqin Yao, Jussi Taipale, Konrad Basler, Philip A Beachy. Cell 2002
Times Cited: 219







List of co-cited articles
1342 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling.
Tamara Caspary, María Jesús García-García, Danwei Huangfu, Jonathan T Eggenschwiler, Michael R Wyler, Andrew S Rakeman, Heather L Alcorn, Kathryn V Anderson. Curr Biol 2002
125
38

Dispatched and scube mediate the efficient secretion of the cholesterol-modified hedgehog ligand.
Hanna Tukachinsky, Ryan P Kuzmickas, Cindy Y Jao, Jing Liu, Adrian Salic. Cell Rep 2012
127
37


Identification of a palmitic acid-modified form of human Sonic hedgehog.
R B Pepinsky, C Zeng, D Wen, P Rayhorn, D P Baker, K P Williams, S A Bixler, C M Ambrose, E A Garber, K Miatkowski,[...]. J Biol Chem 1998
527
35

Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling.
Takatoshi Kawakami, T'Nay Kawcak, Ya-Jun Li, Wanhui Zhang, Yongmei Hu, Pao-Tien Chuang. Development 2002
112
34

Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal.
Z Chamoun, R K Mann, D Nellen, D P von Kessler, M Bellotto, P A Beachy, K Basler. Science 2001
304
34

Scube/You activity mediates release of dually lipid-modified Hedgehog signal in soluble form.
Adrian Creanga, Thomas D Glenn, Randall K Mann, Adam M Saunders, William S Talbot, Philip A Beachy. Genes Dev 2012
88
38

Patched acts catalytically to suppress the activity of Smoothened.
J Taipale, M K Cooper, T Maiti, P A Beachy. Nature 2002
574
33


Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates.
Miao-Hsueh Chen, Ya-Jun Li, Takatoshi Kawakami, Shan-Mei Xu, Pao-Tien Chuang. Genes Dev 2004
250
31

A freely diffusible form of Sonic hedgehog mediates long-range signalling.
X Zeng, J A Goetz, L M Suber, W J Scott, C M Schreiner, D J Robbins. Nature 2001
337
30

Lipoprotein particles are required for Hedgehog and Wingless signalling.
Daniela Panáková, Hein Sprong, Eric Marois, Christoph Thiele, Suzanne Eaton. Nature 2005
474
28

Patched1 regulates hedgehog signaling at the primary cilium.
Rajat Rohatgi, Ljiljana Milenkovic, Matthew P Scott. Science 2007
954
23

Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain.
J A Porter, S C Ekker, W J Park, D P von Kessler, K E Young, C H Chen, Y Ma, A S Woods, R J Cotter, E V Koonin,[...]. Cell 1996
400
23



Mutations affecting segment number and polarity in Drosophila.
C Nüsslein-Volhard, E Wieschaus. Nature 1980
22

Evidence for a role of vertebrate Disp1 in long-range Shh signaling.
L Alton Etheridge, T Quinn Crawford, Shile Zhang, Henk Roelink. Development 2010
47
46

Dispatched mediates Hedgehog basolateral release to form the long-range morphogenetic gradient in the Drosophila wing disk epithelium.
Ainhoa Callejo, Aphrodite Bilioni, Emanuela Mollica, Nicole Gorfinkiel, Germán Andrés, Carmen Ibáñez, Carlos Torroja, Laura Doglio, Javier Sierra, Isabel Guerrero. Proc Natl Acad Sci U S A 2011
115
22

The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice.
Toyoaki Tenzen, Benjamin L Allen, Francesca Cole, Jong-Sun Kang, Robert S Krauss, Andrew P McMahon. Dev Cell 2006
266
21

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog.
D M Stone, M Hynes, M Armanini, T A Swanson, Q Gu, R L Johnson, M P Scott, D Pennica, A Goddard, H Phillips,[...]. Nature 1996
894
21

The mechanisms of Hedgehog signalling and its roles in development and disease.
James Briscoe, Pascal P Thérond. Nat Rev Mol Cell Biol 2013
979
21

Vertebrate Smoothened functions at the primary cilium.
Kevin C Corbit, Pia Aanstad, Veena Singla, Andrew R Norman, Didier Y R Stainier, Jeremy F Reiter. Nature 2005
20

The RND permease superfamily: an ancient, ubiquitous and diverse family that includes human disease and development proteins.
T T Tseng, K S Gratwick, J Kollman, D Park, D H Nies, A Goffeau, M H Saier. J Mol Microbiol Biotechnol 1999
406
20

Altered neural cell fates and medulloblastoma in mouse patched mutants.
L V Goodrich, L Milenković, K M Higgins, M P Scott. Science 1997
19

Biochemical evidence that patched is the Hedgehog receptor.
V Marigo, R A Davey, Y Zuo, J M Cunningham, C J Tabin. Nature 1996
665
19


Cytonemes are required for the establishment of a normal Hedgehog morphogen gradient in Drosophila epithelia.
Marcus Bischoff, Ana-Citlali Gradilla, Irene Seijo, Germán Andrés, Carmen Rodríguez-Navas, Laura González-Méndez, Isabel Guerrero. Nat Cell Biol 2013
141
19

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine.
J Taipale, J K Chen, M K Cooper, B Wang, R K Mann, L Milenkovic, M P Scott, P A Beachy. Nature 2000
18

Autoproteolysis in hedgehog protein biogenesis.
J J Lee, S C Ekker, D P von Kessler, J A Porter, B I Sun, P A Beachy. Science 1994
423
18

The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla.
Jason S McLellan, Xiaoyan Zheng, Glenn Hauk, Rodolfo Ghirlando, Philip A Beachy, Daniel J Leahy. Nature 2008
113
18

Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog in Drosophila epithelia.
Armel Gallet, Laurent Ruel, Laurence Staccini-Lavenant, Pascal P Thérond. Development 2006
104
18

Nanoscale organization of hedgehog is essential for long-range signaling.
Neha Vyas, Debanjan Goswami, A Manonmani, Pranav Sharma, H A Ranganath, K VijayRaghavan, L S Shashidhara, R Sowdhamini, Satyajit Mayor. Cell 2008
111
18

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function.
C Chiang, Y Litingtung, E Lee, K E Young, J L Corden, H Westphal, P A Beachy. Nature 1996
17

Novel lipid modifications of secreted protein signals.
Randall K Mann, Philip A Beachy. Annu Rev Biochem 2004
249
17


Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity.
Y Echelard, D J Epstein, B St-Jacques, L Shen, J Mohler, J A McMahon, A P McMahon. Cell 1993
17

Heparan sulfate-modulated, metalloprotease-mediated sonic hedgehog release from producing cells.
Tabea Dierker, Rita Dreier, Arnd Petersen, Christian Bordych, Kay Grobe. J Biol Chem 2009
70
24


Lipoprotein-heparan sulfate interactions in the Hh pathway.
Christina Eugster, Daniela Panáková, Ali Mahmoud, Suzanne Eaton. Dev Cell 2007
113
17

Scube2 mediates Hedgehog signalling in the zebrafish embryo.
Georgina E Hollway, John Maule, Philippe Gautier, Timothy M Evans, David G Keenan, Claudia Lohs, Danielle Fischer, Carol Wicking, Peter D Currie. Dev Biol 2006
75
22

Cholesterol modification restricts the spread of Shh gradient in the limb bud.
Yina Li, Huimin Zhang, Ying Litingtung, Chin Chiang. Proc Natl Acad Sci U S A 2006
115
17

Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1.
P M Lewis, M P Dunn, J A McMahon, M Logan, J F Martin, B St-Jacques, A P McMahon. Cell 2001
378
17




Hedgehog lipid modifications are required for Hedgehog stabilization in the extracellular matrix.
Ainhoa Callejo, Carlos Torroja, Luis Quijada, Isabel Guerrero. Development 2006
100
16

Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function.
Benjamin L Allen, Jane Y Song, Luisa Izzi, Irene W Althaus, Jong-Sun Kang, Frédéric Charron, Robert S Krauss, Andrew P McMahon. Dev Cell 2011
189
16

Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Xin Gong, Hongwu Qian, Pingping Cao, Xin Zhao, Qiang Zhou, Jianlin Lei, Nieng Yan. Science 2018
105
16


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.