Peter Baumann, Elaine Podell, Thomas R Cech. Mol Cell Biol 2002
Times Cited: 134
Times Cited: 134
Times Cited
Times Co-cited
Similarity
Pot1, the putative telomere end-binding protein in fission yeast and humans.
P Baumann, T R Cech. Science 2001
P Baumann, T R Cech. Science 2001
70
Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection.
Ming Lei, Elaine R Podell, Thomas R Cech. Nat Struct Mol Biol 2004
Ming Lei, Elaine R Podell, Thomas R Cech. Nat Struct Mol Biol 2004
54
Shelterin: the protein complex that shapes and safeguards human telomeres.
Titia de Lange. Genes Dev 2005
Titia de Lange. Genes Dev 2005
50
POT1 as a terminal transducer of TRF1 telomere length control.
Diego Loayza, Titia De Lange. Nature 2003
Diego Loayza, Titia De Lange. Nature 2003
49
POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex.
Jeffrey Zheng-Sheng Ye, Dirk Hockemeyer, Andrew N Krutchinsky, Diego Loayza, Sarah M Hooper, Brian T Chait, Titia de Lange. Genes Dev 2004
Jeffrey Zheng-Sheng Ye, Dirk Hockemeyer, Andrew N Krutchinsky, Diego Loayza, Sarah M Hooper, Brian T Chait, Titia de Lange. Genes Dev 2004
46
PTOP interacts with POT1 and regulates its localization to telomeres.
Dan Liu, Amin Safari, Matthew S O'Connor, Doug W Chan, Andrew Laegeler, Jun Qin, Zhou Songyang. Nat Cell Biol 2004
Dan Liu, Amin Safari, Matthew S O'Connor, Doug W Chan, Andrew Laegeler, Jun Qin, Zhou Songyang. Nat Cell Biol 2004
45
Mammalian telomeres end in a large duplex loop.
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
42
The POT1-TPP1 telomere complex is a telomerase processivity factor.
Feng Wang, Elaine R Podell, Arthur J Zaug, Yuting Yang, Paul Baciu, Thomas R Cech, Ming Lei. Nature 2007
Feng Wang, Elaine R Podell, Arthur J Zaug, Yuting Yang, Paul Baciu, Thomas R Cech, Ming Lei. Nature 2007
41
Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres.
Dirk Hockemeyer, Jan-Peter Daniels, Hiroyuki Takai, Titia de Lange. Cell 2006
Dirk Hockemeyer, Jan-Peter Daniels, Hiroyuki Takai, Titia de Lange. Cell 2006
40
Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres.
Ling Wu, Asha S Multani, Hua He, Wilfredo Cosme-Blanco, Yu Deng, Jian Min Deng, Olga Bachilo, Sen Pathak, Hedioshi Tahara, Susan M Bailey,[...]. Cell 2006
Ling Wu, Asha S Multani, Hua He, Wilfredo Cosme-Blanco, Yu Deng, Jian Min Deng, Olga Bachilo, Sen Pathak, Hedioshi Tahara, Susan M Bailey,[...]. Cell 2006
36
DNA binding features of human POT1: a nonamer 5'-TAGGGTTAG-3' minimal binding site, sequence specificity, and internal binding to multimeric sites.
Diego Loayza, Heather Parsons, Jill Donigian, Kristina Hoke, Titia de Lange. J Biol Chem 2004
Diego Loayza, Heather Parsons, Jill Donigian, Kristina Hoke, Titia de Lange. J Biol Chem 2004
30
Loss of hPot1 function leads to telomere instability and a cut-like phenotype.
Timothy Veldman, Katherine T Etheridge, Christopher M Counter. Curr Biol 2004
Timothy Veldman, Katherine T Etheridge, Christopher M Counter. Curr Biol 2004
30
Human POT1 facilitates telomere elongation by telomerase.
Lorel M Colgin, Katherine Baran, Peter Baumann, Thomas R Cech, Roger R Reddel. Curr Biol 2003
Lorel M Colgin, Katherine Baran, Peter Baumann, Thomas R Cech, Roger R Reddel. Curr Biol 2003
29
DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA.
Ming Lei, Elaine R Podell, Peter Baumann, Thomas R Cech. Nature 2003
Ming Lei, Elaine R Podell, Peter Baumann, Thomas R Cech. Nature 2003
29
TRF2 protects human telomeres from end-to-end fusions.
B van Steensel, A Smogorzewska, T de Lange. Cell 1998
B van Steensel, A Smogorzewska, T de Lange. Cell 1998
29
Control of telomere length by the human telomeric protein TRF1.
B van Steensel, T de Lange. Nature 1997
B van Steensel, T de Lange. Nature 1997
28
TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres.
Jeffrey Zheng-Sheng Ye, Jill R Donigian, Megan van Overbeek, Diego Loayza, Yan Luo, Andrew N Krutchinsky, Brian T Chait, Titia de Lange. J Biol Chem 2004
Jeffrey Zheng-Sheng Ye, Jill R Donigian, Megan van Overbeek, Diego Loayza, Yan Luo, Andrew N Krutchinsky, Brian T Chait, Titia de Lange. J Biol Chem 2004
28
TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase.
Huawei Xin, Dan Liu, Ma Wan, Amin Safari, Hyeung Kim, Wen Sun, Matthew S O'Connor, Zhou Songyang. Nature 2007
Huawei Xin, Dan Liu, Ma Wan, Amin Safari, Hyeung Kim, Wen Sun, Matthew S O'Connor, Zhou Songyang. Nature 2007
28
POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end.
Dirk Hockemeyer, Agnel J Sfeir, Jerry W Shay, Woodring E Wright, Titia de Lange. EMBO J 2005
Dirk Hockemeyer, Agnel J Sfeir, Jerry W Shay, Woodring E Wright, Titia de Lange. EMBO J 2005
27
Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2.
D Broccoli, A Smogorzewska, L Chong, T de Lange. Nat Genet 1997
D Broccoli, A Smogorzewska, L Chong, T de Lange. Nat Genet 1997
26
TIN2, a new regulator of telomere length in human cells.
S H Kim, P Kaminker, J Campisi. Nat Genet 1999
S H Kim, P Kaminker, J Campisi. Nat Genet 1999
25
The Arabidopsis Pot1 and Pot2 proteins function in telomere length homeostasis and chromosome end protection.
Eugene V Shakirov, Yulia V Surovtseva, Nathan Osbun, Dorothy E Shippen. Mol Cell Biol 2005
Eugene V Shakirov, Yulia V Surovtseva, Nathan Osbun, Dorothy E Shippen. Mol Cell Biol 2005
25
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
Eros Lazzerini Denchi, Titia de Lange. Nature 2007
Eros Lazzerini Denchi, Titia de Lange. Nature 2007
24
A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2.
Benjamin R Houghtaling, Leanora Cuttonaro, William Chang, Susan Smith. Curr Biol 2004
Benjamin R Houghtaling, Leanora Cuttonaro, William Chang, Susan Smith. Curr Biol 2004
23
DNA damage foci at dysfunctional telomeres.
Hiroyuki Takai, Agata Smogorzewska, Titia de Lange. Curr Biol 2003
Hiroyuki Takai, Agata Smogorzewska, Titia de Lange. Curr Biol 2003
22
POT1 and TRF2 cooperate to maintain telomeric integrity.
Qin Yang, Yun-Ling Zheng, Curtis C Harris. Mol Cell Biol 2005
Qin Yang, Yun-Ling Zheng, Curtis C Harris. Mol Cell Biol 2005
22
Crystal structure of the Oxytricha nova telomere end binding protein complexed with single strand DNA.
M P Horvath, V L Schweiker, J M Bevilacqua, J A Ruggles, S C Schultz. Cell 1998
M P Horvath, V L Schweiker, J M Bevilacqua, J A Ruggles, S C Schultz. Cell 1998
21
Control of human telomere length by TRF1 and TRF2.
A Smogorzewska, B van Steensel, A Bianchi, S Oelmann, M R Schaefer, G Schnapp, T de Lange. Mol Cell Biol 2000
A Smogorzewska, B van Steensel, A Bianchi, S Oelmann, M R Schaefer, G Schnapp, T de Lange. Mol Cell Biol 2000
20
Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins.
Dan Liu, Matthew S O'Connor, Jun Qin, Zhou Songyang. J Biol Chem 2004
Dan Liu, Matthew S O'Connor, Jun Qin, Zhou Songyang. J Biol Chem 2004
20
Switching human telomerase on and off with hPOT1 protein in vitro.
Ming Lei, Arthur J Zaug, Elaine R Podell, Thomas R Cech. J Biol Chem 2005
Ming Lei, Arthur J Zaug, Elaine R Podell, Thomas R Cech. J Biol Chem 2005
20
Regulation of telomerase by telomeric proteins.
Agata Smogorzewska, Titia de Lange. Annu Rev Biochem 2004
Agata Smogorzewska, Titia de Lange. Annu Rev Biochem 2004
19
Cell cycle localization, dimerization, and binding domain architecture of the telomere protein cPot1.
Chao Wei, Carolyn M Price. Mol Cell Biol 2004
Chao Wei, Carolyn M Price. Mol Cell Biol 2004
51
Human protection of telomeres 1 (POT1) is a negative regulator of telomerase activity in vitro.
Colleen Kelleher, Isabel Kurth, Joachim Lingner. Mol Cell Biol 2005
Colleen Kelleher, Isabel Kurth, Joachim Lingner. Mol Cell Biol 2005
19
p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2.
J Karlseder, D Broccoli, Y Dai, S Hardy, T de Lange. Science 1999
J Karlseder, D Broccoli, Y Dai, S Hardy, T de Lange. Science 1999
18
Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
18
Identification of human Rap1: implications for telomere evolution.
B Li, S Oestreich, T de Lange. Cell 2000
B Li, S Oestreich, T de Lange. Cell 2000
18
18
Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening.
V L Makarov, Y Hirose, J P Langmore. Cell 1997
V L Makarov, Y Hirose, J P Langmore. Cell 1997
17
POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination.
Hua He, Asha S Multani, Wilfredo Cosme-Blanco, Hidetoshi Tahara, Jin Ma, Sen Pathak, Yibin Deng, Sandy Chang. EMBO J 2006
Hua He, Asha S Multani, Wilfredo Cosme-Blanco, Hidetoshi Tahara, Jin Ma, Sen Pathak, Yibin Deng, Sandy Chang. EMBO J 2006
19
Telomere protection by mammalian Pot1 requires interaction with Tpp1.
Dirk Hockemeyer, Wilhelm Palm, Tobias Else, Jan-Peter Daniels, Kaori K Takai, Jeffrey Z-S Ye, Catherine E Keegan, Titia de Lange, Gary D Hammer. Nat Struct Mol Biol 2007
Dirk Hockemeyer, Wilhelm Palm, Tobias Else, Jan-Peter Daniels, Kaori K Takai, Jeffrey Z-S Ye, Catherine E Keegan, Titia de Lange, Gary D Hammer. Nat Struct Mol Biol 2007
17
Cdc13 delivers separate complexes to the telomere for end protection and replication.
E Pennock, K Buckley, V Lundblad. Cell 2001
E Pennock, K Buckley, V Lundblad. Cell 2001
16
T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang.
R M Stansel, T de Lange, J D Griffith. EMBO J 2001
R M Stansel, T de Lange, J D Griffith. EMBO J 2001
16
TIN2 mediates functions of TRF2 at human telomeres.
Sahn-ho Kim, Christian Beausejour, Albert R Davalos, Patrick Kaminker, Seok-Jin Heo, Judith Campisi. J Biol Chem 2004
Sahn-ho Kim, Christian Beausejour, Albert R Davalos, Patrick Kaminker, Seok-Jin Heo, Judith Campisi. J Biol Chem 2004
16
Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro.
Arthur J Zaug, Elaine R Podell, Thomas R Cech. Proc Natl Acad Sci U S A 2005
Arthur J Zaug, Elaine R Podell, Thomas R Cech. Proc Natl Acad Sci U S A 2005
16
Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint.
B Garvik, M Carson, L Hartwell. Mol Cell Biol 1995
B Garvik, M Carson, L Hartwell. Mol Cell Biol 1995
15
Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance.
C I Nugent, T R Hughes, N F Lue, V Lundblad. Science 1996
C I Nugent, T R Hughes, N F Lue, V Lundblad. Science 1996
15
Cooperative binding of single-stranded telomeric DNA by the Pot1 protein of Schizosaccharomyces pombe.
Ming Lei, Peter Baumann, Thomas R Cech. Biochemistry 2002
Ming Lei, Peter Baumann, Thomas R Cech. Biochemistry 2002
20
Extension of life-span by introduction of telomerase into normal human cells.
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
15
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.