A citation-based method for searching scientific literature

Celia P Briscoe, Mohammad Tadayyon, John L Andrews, William G Benson, Jon K Chambers, Michelle M Eilert, Catherine Ellis, Nabil A Elshourbagy, Aaron S Goetz, Dana T Minnick, Paul R Murdock, Howard R Sauls, Usman Shabon, Lisa D Spinage, Jay C Strum, Philip G Szekeres, Kong B Tan, James M Way, Diane M Ignar, Shelagh Wilson, Alison I Muir. J Biol Chem 2003
Times Cited: 818







List of co-cited articles
1077 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.
Yasuaki Itoh, Yuji Kawamata, Masataka Harada, Makoto Kobayashi, Ryo Fujii, Shoji Fukusumi, Kazuhiro Ogi, Masaki Hosoya, Yasuhiro Tanaka, Hiroshi Uejima,[...]. Nature 2003
66

Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120.
Akira Hirasawa, Keiko Tsumaya, Takeo Awaji, Susumu Katsuma, Tetsuya Adachi, Masateru Yamada, Yukihiko Sugimoto, Shunichi Miyazaki, Gozoh Tsujimoto. Nat Med 2005
31

GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects.
Da Young Oh, Saswata Talukdar, Eun Ju Bae, Takeshi Imamura, Hidetaka Morinaga, WuQiang Fan, Pingping Li, Wendell J Lu, Steven M Watkins, Jerrold M Olefsky. Cell 2010
28

Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules.
Celia P Briscoe, Andrew J Peat, Stephen C McKeown, David F Corbett, Aaron S Goetz, Thomas R Littleton, David C McCoy, Terry P Kenakin, John L Andrews, Carina Ammala,[...]. Br J Pharmacol 2006
324
23



GPR40 (FFAR1) - Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo.
Maria Hauge, Marie A Vestmar, Anna S Husted, Jeppe P Ekberg, Michael J Wright, Jerry Di Salvo, Adam B Weinglass, Maja S Engelstoft, Andreas N Madsen, Michael Lückmann,[...]. Mol Metab 2014
133
18

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.
Andrew J Brown, Susan M Goldsworthy, Ashley A Barnes, Michelle M Eilert, Lili Tcheang, Dion Daniels, Alison I Muir, Mark J Wigglesworth, Ian Kinghorn, Neil J Fraser,[...]. J Biol Chem 2003
17

A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs.
Knut Kotarsky, Niclas E Nilsson, Erik Flodgren, Christer Owman, Björn Olde. Biochem Biophys Res Commun 2003
291
16

Role of GPR40 in fatty acid action on the beta cell line INS-1E.
Hagit Shapiro, Sigal Shachar, Israel Sekler, Michal Hershfinkel, Michael D Walker. Biochem Biophys Res Commun 2005
171
16

The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse.
Pär Steneberg, Nir Rubins, Reut Bartoov-Shifman, Michael D Walker, Helena Edlund. Cell Metab 2005
326
16

Complex Pharmacology of Free Fatty Acid Receptors.
Graeme Milligan, Bharat Shimpukade, Trond Ulven, Brian D Hudson. Chem Rev 2017
124
15


Free Fatty Acid Receptors in Health and Disease.
Ikuo Kimura, Atsuhiko Ichimura, Ryuji Ohue-Kitano, Miki Igarashi. Physiol Rev 2020
171
15

TAK-875 versus placebo or glimepiride in type 2 diabetes mellitus: a phase 2, randomised, double-blind, placebo-controlled trial.
Charles F Burant, Prabhakar Viswanathan, John Marcinak, Charlie Cao, Majid Vakilynejad, Benhuai Xie, Eckhard Leifke. Lancet 2012
202
14

A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice.
Da Young Oh, Evelyn Walenta, Taro E Akiyama, William S Lagakos, Denise Lackey, Ariane R Pessentheiner, Roman Sasik, Nasun Hah, Tyler J Chi, Jason M Cox,[...]. Nat Med 2014
240
14

Free fatty acid receptor agonists for the treatment of type 2 diabetes: drugs in preclinical to phase II clinical development.
Zheng Li, Qianqian Qiu, Xinqian Geng, Jianyong Yang, Wenlong Huang, Hai Qian. Expert Opin Investig Drugs 2016
67
20

A potent class of GPR40 full agonists engages the enteroinsular axis to promote glucose control in rodents.
Jian Luo, Gayathri Swaminath, Sean P Brown, Jane Zhang, Qi Guo, Michael Chen, Kathy Nguyen, Thanhvien Tran, Lynn Miao, Paul J Dransfield,[...]. PLoS One 2012
100
13

Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human.
Atsuhiko Ichimura, Akira Hirasawa, Odile Poulain-Godefroy, Amélie Bonnefond, Takafumi Hara, Loïc Yengo, Ikuo Kimura, Audrey Leloire, Ning Liu, Keiko Iida,[...]. Nature 2012
445
13

The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding.
Melkam Kebede, Thierry Alquier, Martin G Latour, Meriem Semache, Caroline Tremblay, Vincent Poitout. Diabetes 2008
133
13

Lack of FFAR1/GPR40 does not protect mice from high-fat diet-induced metabolic disease.
Hong Lan, Lizbeth M Hoos, Li Liu, Glen Tetzloff, Weiwen Hu, Susan J Abbondanzo, Galya Vassileva, Eric L Gustafson, Joseph A Hedrick, Harry R Davis. Diabetes 2008
102
13


The regulation of adipogenesis through GPR120.
Chizu Gotoh, Yeon-Hee Hong, Tomoyo Iga, Daisuke Hishikawa, Yasuki Suzuki, Sang-Houn Song, Ki-Choon Choi, Tetsuya Adachi, Akira Hirasawa, Gozoh Tsujimoto,[...]. Biochem Biophys Res Commun 2007
179
12

Discovery of TAK-875: A Potent, Selective, and Orally Bioavailable GPR40 Agonist.
Nobuyuki Negoro, Shinobu Sasaki, Satoshi Mikami, Masahiro Ito, Masami Suzuki, Yoshiyuki Tsujihata, Ryo Ito, Ayako Harada, Koji Takeuchi, Nobuhiro Suzuki,[...]. ACS Med Chem Lett 2010
185
12


Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation.
Nathalia R V Dragano, Carina Solon, Albina F Ramalho, Rodrigo F de Moura, Daniela S Razolli, Elisabeth Christiansen, Carlos Azevedo, Trond Ulven, Licio A Velloso. J Neuroinflammation 2017
73
15

Discovery of AM-1638: A Potent and Orally Bioavailable GPR40/FFA1 Full Agonist.
Sean P Brown, Paul J Dransfield, Marc Vimolratana, XianYun Jiao, Liusheng Zhu, Vatee Pattaropong, Ying Sun, Jinqian Liu, Jian Luo, Jane Zhang,[...]. ACS Med Chem Lett 2012
66
16

Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation.
Emmanuel Le Poul, Cecile Loison, Sofie Struyf, Jean-Yves Springael, Vincent Lannoy, Marie-Eve Decobecq, Stephane Brezillon, Vincent Dupriez, Gilbert Vassart, Jo Van Damme,[...]. J Biol Chem 2003
939
11

A novel antidiabetic drug, fasiglifam/TAK-875, acts as an ago-allosteric modulator of FFAR1.
Chiori Yabuki, Hidetoshi Komatsu, Yoshiyuki Tsujihata, Risa Maeda, Ryo Ito, Kae Matsuda-Nagasumi, Kensuke Sakuma, Kazumasa Miyawaki, Naoya Kikuchi, Koji Takeuchi,[...]. PLoS One 2013
70
15

GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo.
Martin G Latour, Thierry Alquier, Elizabeth Oseid, Caroline Tremblay, Thomas L Jetton, Jian Luo, Daniel C-H Lin, Vincent Poitout. Diabetes 2007
209
11

Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells.
Maja S Engelstoft, Won-Mee Park, Ichiro Sakata, Line V Kristensen, Anna Sofie Husted, Sherri Osborne-Lawrence, Paul K Piper, Angela K Walker, Maria H Pedersen, Mark K Nøhr,[...]. Mol Metab 2013
212
11


Identification and pharmacological characterization of multiple allosteric binding sites on the free fatty acid 1 receptor.
Daniel C-H Lin, Qi Guo, Jian Luo, Jane Zhang, Kathy Nguyen, Michael Chen, Thanh Tran, Paul J Dransfield, Sean P Brown, Jonathan Houze,[...]. Mol Pharmacol 2012
94
11

Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2.
Gwen Tolhurst, Helen Heffron, Yu Shan Lam, Helen E Parker, Abdella M Habib, Eleftheria Diakogiannaki, Jennifer Cameron, Johannes Grosse, Frank Reimann, Fiona M Gribble. Diabetes 2012
10

Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes.
Cong Tang, Kashan Ahmed, Andreas Gille, Shun Lu, Hermann-Josef Gröne, Sorin Tunaru, Stefan Offermanns. Nat Med 2015
181
10

Overexpression of GPR40 in pancreatic beta-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice.
Kae Nagasumi, Ritsuko Esaki, Kimihiko Iwachidow, Yoshitaka Yasuhara, Kazuhiro Ogi, Hideyuki Tanaka, Mitsugu Nakata, Takashi Yano, Kozo Shimakawa, Shigehisa Taketomi,[...]. Diabetes 2009
154
10

Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids.
Hongfei Ge, Xiaofan Li, Jennifer Weiszmann, Ping Wang, Helene Baribault, Jin-Long Chen, Hui Tian, Yang Li. Endocrinology 2008
319
10

β-Arrestin Recruitment and Biased Agonism at Free Fatty Acid Receptor 1.
Arturo D Mancini, Gyslaine Bertrand, Kevin Vivot, Éric Carpentier, Caroline Tremblay, Julien Ghislain, Michel Bouvier, Vincent Poitout. J Biol Chem 2015
63
15


Current status of GPR40/FFAR1 modulators in medicinal chemistry (2016-2019): a patent review.
Zheng Li, Zongtao Zhou, Luyong Zhang. Expert Opin Ther Pat 2020
24
41

SCO-267, a GPR40 Full Agonist, Improves Glycemic and Body Weight Control in Rat Models of Diabetes and Obesity.
Hikaru Ueno, Ryo Ito, Shin-Ichi Abe, Mitsugi Ookawara, Hirohisa Miyashita, Hitomi Ogino, Yasufumi Miyamoto, Tomoki Yoshihara, Akihiro Kobayashi, Yoshiyuki Tsujihata,[...]. J Pharmacol Exp Ther 2019
22
45

Differential signaling by splice variants of the human free fatty acid receptor GPR120.
Sarah-Jane Watson, Alastair J H Brown, Nicholas D Holliday. Mol Pharmacol 2012
101
9

The pharmacology of TUG-891, a potent and selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), demonstrates both potential opportunity and possible challenges to therapeutic agonism.
Brian D Hudson, Bharat Shimpukade, Amanda E Mackenzie, Adrian J Butcher, John D Pediani, Elisabeth Christiansen, Helen Heathcote, Andrew B Tobin, Trond Ulven, Graeme Milligan. Mol Pharmacol 2013
140
9

GPR120 (FFAR4) is preferentially expressed in pancreatic delta cells and regulates somatostatin secretion from murine islets of Langerhans.
Virginia M Stone, Shalinee Dhayal, Katy J Brocklehurst, Carol Lenaghan, Maria Sörhede Winzell, Mårten Hammar, Xiufeng Xu, David M Smith, Noel G Morgan. Diabetologia 2014
90
10

Free fatty acid (FFA) and hydroxy carboxylic acid (HCA) receptors.
Stefan Offermanns. Annu Rev Pharmacol Toxicol 2014
98
9

Activity of dietary fatty acids on FFA1 and FFA4 and characterisation of pinolenic acid as a dual FFA1/FFA4 agonist with potential effect against metabolic diseases.
Elisabeth Christiansen, Kenneth R Watterson, Claire J Stocker, Elena Sokol, Laura Jenkins, Katharina Simon, Manuel Grundmann, Rasmus K Petersen, Edward T Wargent, Brian D Hudson,[...]. Br J Nutr 2015
65
13

A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1.
M Sawzdargo, S R George, T Nguyen, S Xu, L F Kolakowski, B F O'Dowd. Biochem Biophys Res Commun 1997
161
9

High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875.
Ankita Srivastava, Jason Yano, Yoshihiko Hirozane, Georgia Kefala, Franz Gruswitz, Gyorgy Snell, Weston Lane, Anthony Ivetac, Kathleen Aertgeerts, Jasmine Nguyen,[...]. Nature 2014
238
9

Free fatty acid receptors FFAR1 and GPR120 as novel therapeutic targets for metabolic disorders.
Takafumi Hara, Akira Hirasawa, Atsuhiko Ichimura, Ikuo Kimura, Gozoh Tsujimoto. J Pharm Sci 2011
124
9

The fatty acid receptor FFA1/GPR40 a decade later: how much do we know?
Arturo D Mancini, Vincent Poitout. Trends Endocrinol Metab 2013
112
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.