Heiko Braak, Kelly Del Tredici, Udo Rüb, Rob A I de Vos, Ernst N H Jansen Steur, Eva Braak. Neurobiol Aging 2003
Times Cited: 6001
Times Cited: 6001
Times Cited
Times Co-cited
Similarity
Alpha-synuclein in Lewy bodies.
M G Spillantini, M L Schmidt, V M Lee, J Q Trojanowski, R Jakes, M Goedert. Nature 1997
M G Spillantini, M L Schmidt, V M Lee, J Q Trojanowski, R Jakes, M Goedert. Nature 1997
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alpha-Synuclein locus triplication causes Parkinson's disease.
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Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death.
Laura A Volpicelli-Daley, Kelvin C Luk, Tapan P Patel, Selcuk A Tanik, Dawn M Riddle, Anna Stieber, David F Meaney, John Q Trojanowski, Virginia M-Y Lee. Neuron 2011
Laura A Volpicelli-Daley, Kelvin C Luk, Tapan P Patel, Selcuk A Tanik, Dawn M Riddle, Anna Stieber, David F Meaney, John Q Trojanowski, Virginia M-Y Lee. Neuron 2011
11
MDS clinical diagnostic criteria for Parkinson's disease.
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Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation.
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Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice.
Kelvin C Luk, Victoria Kehm, Jenna Carroll, Bin Zhang, Patrick O'Brien, John Q Trojanowski, Virginia M-Y Lee. Science 2012
Kelvin C Luk, Victoria Kehm, Jenna Carroll, Bin Zhang, Patrick O'Brien, John Q Trojanowski, Virginia M-Y Lee. Science 2012
10
Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease.
Jeffrey H Kordower, Yaping Chu, Robert A Hauser, Thomas B Freeman, C Warren Olanow. Nat Med 2008
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10
Prion-like spreading of pathological α-synuclein in brain.
Masami Masuda-Suzukake, Takashi Nonaka, Masato Hosokawa, Takayuki Oikawa, Tetsuaki Arai, Haruhiko Akiyama, David M A Mann, Masato Hasegawa. Brain 2013
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10
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease.
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Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease.
Timothy R Sampson, Justine W Debelius, Taren Thron, Stefan Janssen, Gauri G Shastri, Zehra Esra Ilhan, Collin Challis, Catherine E Schretter, Sandra Rocha, Viviana Gradinaru,[...]. Cell 2016
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Neuropathological stageing of Alzheimer-related changes.
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Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes.
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9
alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies.
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Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson's Disease.
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9
The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration.
Anne-Laure Mahul-Mellier, Johannes Burtscher, Niran Maharjan, Laura Weerens, Marie Croisier, Fabien Kuttler, Marion Leleu, Graham W Knott, Hilal A Lashuel. Proc Natl Acad Sci U S A 2020
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9
Gastric alpha-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology.
Heiko Braak, Rob A I de Vos, Jürgen Bohl, Kelly Del Tredici. Neurosci Lett 2006
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8
Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival.
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7
Stages in the development of Parkinson's disease-related pathology.
Heiko Braak, Estifanos Ghebremedhin, Udo Rüb, Hansjürgen Bratzke, Kelly Del Tredici. Cell Tissue Res 2004
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7
Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.
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7
alpha-Synuclein is phosphorylated in synucleinopathy lesions.
Hideo Fujiwara, Masato Hasegawa, Naoshi Dohmae, Akiko Kawashima, Eliezer Masliah, Matthew S Goldberg, Jie Shen, Koji Takio, Takeshi Iwatsubo. Nat Cell Biol 2002
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Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium.
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7
Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.
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7
Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite-like aggregates.
Laura A Volpicelli-Daley, Kelvin C Luk, Virginia M-Y Lee. Nat Protoc 2014
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7
α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation.
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6
Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys.
Ariadna Recasens, Benjamin Dehay, Jordi Bové, Iria Carballo-Carbajal, Sandra Dovero, Ana Pérez-Villalba, Pierre-Olivier Fernagut, Javier Blesa, Annabelle Parent, Celine Perier,[...]. Ann Neurol 2014
Ariadna Recasens, Benjamin Dehay, Jordi Bové, Iria Carballo-Carbajal, Sandra Dovero, Ana Pérez-Villalba, Pierre-Olivier Fernagut, Javier Blesa, Annabelle Parent, Celine Perier,[...]. Ann Neurol 2014
6
Gut microbiota are related to Parkinson's disease and clinical phenotype.
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Filip Scheperjans, Velma Aho, Pedro A B Pereira, Kaisa Koskinen, Lars Paulin, Eero Pekkonen, Elena Haapaniemi, Seppo Kaakkola, Johanna Eerola-Rautio, Marjatta Pohja,[...]. Mov Disord 2015
6
Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.
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6
Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study.
Ronald B Postuma, Alex Iranzo, Michele Hu, Birgit Högl, Bradley F Boeve, Raffaele Manni, Wolfgang H Oertel, Isabelle Arnulf, Luigi Ferini-Strambi, Monica Puligheddu,[...]. Brain 2019
Ronald B Postuma, Alex Iranzo, Michele Hu, Birgit Högl, Bradley F Boeve, Raffaele Manni, Wolfgang H Oertel, Isabelle Arnulf, Luigi Ferini-Strambi, Monica Puligheddu,[...]. Brain 2019
6
In vivo demonstration that alpha-synuclein oligomers are toxic.
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6
Structures of α-synuclein filaments from multiple system atrophy.
Manuel Schweighauser, Yang Shi, Airi Tarutani, Fuyuki Kametani, Alexey G Murzin, Bernardino Ghetti, Tomoyasu Matsubara, Taisuke Tomita, Takashi Ando, Kazuko Hasegawa,[...]. Nature 2020
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6
Unified staging system for Lewy body disorders: correlation with nigrostriatal degeneration, cognitive impairment and motor dysfunction.
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6
Non-motor features of Parkinson disease.
Anthony H V Schapira, K Ray Chaudhuri, Peter Jenner. Nat Rev Neurosci 2017
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6
Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases.
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6
Structural and functional characterization of two alpha-synuclein strains.
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6
Alpha-synuclein locus duplication as a cause of familial Parkinson's disease.
Marie-Christine Chartier-Harlin, Jennifer Kachergus, Christophe Roumier, Vincent Mouroux, Xavier Douay, Sarah Lincoln, Clotilde Levecque, Lydie Larvor, Joris Andrieux, Mary Hulihan,[...]. Lancet 2004
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6
Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies.
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6
Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells.
Kelvin C Luk, Cheng Song, Patrick O'Brien, Anna Stieber, Jonathan R Branch, Kurt R Brunden, John Q Trojanowski, Virginia M-Y Lee. Proc Natl Acad Sci U S A 2009
Kelvin C Luk, Cheng Song, Patrick O'Brien, Anna Stieber, Jonathan R Branch, Kurt R Brunden, John Q Trojanowski, Virginia M-Y Lee. Proc Natl Acad Sci U S A 2009
6
Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls.
Marcus M Unger, Jörg Spiegel, Klaus-Ulrich Dillmann, David Grundmann, Hannah Philippeit, Jan Bürmann, Klaus Faßbender, Andreas Schwiertz, Karl-Herbert Schäfer. Parkinsonism Relat Disord 2016
Marcus M Unger, Jörg Spiegel, Klaus-Ulrich Dillmann, David Grundmann, Hannah Philippeit, Jan Bürmann, Klaus Faßbender, Andreas Schwiertz, Karl-Herbert Schäfer. Parkinsonism Relat Disord 2016
5
Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome.
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5
Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naïve Parkinson's disease patients.
J R Bedarf, F Hildebrand, L P Coelho, S Sunagawa, M Bahram, F Goeser, P Bork, U Wüllner. Genome Med 2017
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5
Structural changes of gut microbiota in Parkinson's disease and its correlation with clinical features.
Wei Li, Xiaoli Wu, Xu Hu, Tao Wang, Shan Liang, Yunfeng Duan, Feng Jin, Bin Qin. Sci China Life Sci 2017
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5
The Synucleinopathies: Twenty Years On.
Michel Goedert, Ross Jakes, Maria Grazia Spillantini. J Parkinsons Dis 2017
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5
α-Synuclein strains cause distinct synucleinopathies after local and systemic administration.
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5
Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease.
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5
Cell Biology and Pathophysiology of α-Synuclein.
Jacqueline Burré, Manu Sharma, Thomas C Südhof. Cold Spring Harb Perspect Med 2018
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5
Parkinson disease.
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5
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease.
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5
Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen.
H Braak, U Rüb, W P Gai, K Del Tredici. J Neural Transm (Vienna) 2003
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5
α-Synuclein transfer between neurons and astrocytes indicates that astrocytes play a role in degradation rather than in spreading.
Frida Loria, Jessica Y Vargas, Luc Bousset, Sylvie Syan, Audrey Salles, Ronald Melki, Chiara Zurzolo. Acta Neuropathol 2017
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5
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.