R J Nijveldt, T Teerlink, M P C Siroen, A A van Lambalgen, J A Rauwerda, P A M van Leeuwen. Clin Nutr 2003
Times Cited: 134
Times Cited: 134
Times Cited
Times Co-cited
Similarity
Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure.
P Vallance, A Leone, A Calver, J Collier, S Moncada. Lancet 1992
P Vallance, A Leone, A Calver, J Collier, S Moncada. Lancet 1992
41
Asymmetrical dimethylarginine (ADMA) in critically ill patients: high plasma ADMA concentration is an independent risk factor of ICU mortality.
R J Nijveldt, T Teerlink, B Van Der Hoven, M P C Siroen, D J Kuik, J A Rauwerda, P A M van Leeuwen. Clin Nutr 2003
R J Nijveldt, T Teerlink, B Van Der Hoven, M P C Siroen, D J Kuik, J A Rauwerda, P A M van Leeuwen. Clin Nutr 2003
28
Asymmetric dimethylarginine causes hypertension and cardiac dysfunction in humans and is actively metabolized by dimethylarginine dimethylaminohydrolase.
Vinod Achan, Michael Broadhead, Mohammed Malaki, Guy Whitley, James Leiper, Raymond MacAllister, Patrick Vallance. Arterioscler Thromb Vasc Biol 2003
Vinod Achan, Michael Broadhead, Mohammed Malaki, Guy Whitley, James Leiper, Raymond MacAllister, Patrick Vallance. Arterioscler Thromb Vasc Biol 2003
26
The human liver clears both asymmetric and symmetric dimethylarginine.
Michiel P C Siroen, Joost R M van der Sijp, Tom Teerlink, Cors van Schaik, Robert J Nijveldt, Paul A M van Leeuwen. Hepatology 2005
Michiel P C Siroen, Joost R M van der Sijp, Tom Teerlink, Cors van Schaik, Robert J Nijveldt, Paul A M van Leeuwen. Hepatology 2005
32
Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase.
Ken Y Lin, Akira Ito, Tomoko Asagami, Philip S Tsao, Shanthi Adimoolam, Masumi Kimoto, Hideaki Tsuji, Gerald M Reaven, John P Cooke. Circulation 2002
Ken Y Lin, Akira Ito, Tomoko Asagami, Philip S Tsao, Shanthi Adimoolam, Masumi Kimoto, Hideaki Tsuji, Gerald M Reaven, John P Cooke. Circulation 2002
25
Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia.
R H Böger, S M Bode-Böger, A Szuba, P S Tsao, J R Chan, O Tangphao, T F Blaschke, J P Cooke. Circulation 1998
R H Böger, S M Bode-Böger, A Szuba, P S Tsao, J R Chan, O Tangphao, T F Blaschke, J P Cooke. Circulation 1998
24
Plasma concentration of asymmetrical dimethylarginine and mortality in patients with end-stage renal disease: a prospective study.
C Zoccali, S Bode-Böger, F Mallamaci, F Benedetto, G Tripepi, L Malatino, A Cataliotti, I Bellanuova, I Fermo, J Frölich,[...]. Lancet 2001
C Zoccali, S Bode-Böger, F Mallamaci, F Benedetto, G Tripepi, L Malatino, A Cataliotti, I Bellanuova, I Fermo, J Frölich,[...]. Lancet 2001
23
Novel mechanism for endothelial dysfunction: dysregulation of dimethylarginine dimethylaminohydrolase.
A Ito, P S Tsao, S Adimoolam, M Kimoto, T Ogawa, J P Cooke. Circulation 1999
A Ito, P S Tsao, S Adimoolam, M Kimoto, T Ogawa, J P Cooke. Circulation 1999
22
Plasma concentrations of nitric oxide and asymmetric dimethylarginine in human alcoholic cirrhosis.
Paloma Lluch, Belén Torondel, Pascual Medina, Gloria Segarra, Juan A Del Olmo, Miguel A Serra, José M Rodrigo. J Hepatol 2004
Paloma Lluch, Belén Torondel, Pascual Medina, Gloria Segarra, Juan A Del Olmo, Miguel A Serra, José M Rodrigo. J Hepatol 2004
26
Interference of L-arginine analogues with L-arginine transport mediated by the y+ carrier hCAT-2B.
E I Closs, F Z Basha, A Habermeier, U Förstermann. Nitric Oxide 1997
E I Closs, F Z Basha, A Habermeier, U Förstermann. Nitric Oxide 1997
22
Cardiovascular biology of the asymmetric dimethylarginine:dimethylarginine dimethylaminohydrolase pathway.
Patrick Vallance, James Leiper. Arterioscler Thromb Vasc Biol 2004
Patrick Vallance, James Leiper. Arterioscler Thromb Vasc Biol 2004
22
Dimethylarginine dimethylaminohydrolase (DDAH): expression, regulation, and function in the cardiovascular and renal systems.
Fredrik Palm, Maristela L Onozato, Zaiming Luo, Christopher S Wilcox. Am J Physiol Heart Circ Physiol 2007
Fredrik Palm, Maristela L Onozato, Zaiming Luo, Christopher S Wilcox. Am J Physiol Heart Circ Physiol 2007
22
Increasing dimethylarginine levels are associated with adverse clinical outcome in severe alcoholic hepatitis.
Rajeshwar P Mookerjee, Mohammed Malaki, Nathan A Davies, Stephen J Hodges, R Neil Dalton, Charles Turner, Sambit Sen, Roger Williams, James Leiper, Patrick Vallance,[...]. Hepatology 2007
Rajeshwar P Mookerjee, Mohammed Malaki, Nathan A Davies, Stephen J Hodges, R Neil Dalton, Charles Turner, Sambit Sen, Roger Williams, James Leiper, Patrick Vallance,[...]. Hepatology 2007
23
Handling of asymmetrical dimethylarginine and symmetrical dimethylarginine by the rat kidney under basal conditions and during endotoxaemia.
Robert J Nijveldt, Tom Teerlink, Coen van Guldener, Hubert A Prins, Antonie A van Lambalgen, Coen D A Stehouwer, Jan A Rauwerda, Paul A M van Leeuwen. Nephrol Dial Transplant 2003
Robert J Nijveldt, Tom Teerlink, Coen van Guldener, Hubert A Prins, Antonie A van Lambalgen, Coen D A Stehouwer, Jan A Rauwerda, Paul A M van Leeuwen. Nephrol Dial Transplant 2003
24
The transplanted liver graft is capable of clearing asymmetric dimethylarginine.
Michiel P C Siroen, Michiel C Warlé, Tom Teerlink, Robert J Nijveldt, Ernst J Kuipers, Herold J Metselaar, Hugo W Tilanus, Dirk J Kuik, Joost R M van der Sijp, Sybren Meijer,[...]. Liver Transpl 2004
Michiel P C Siroen, Michiel C Warlé, Tom Teerlink, Robert J Nijveldt, Ernst J Kuipers, Herold J Metselaar, Hugo W Tilanus, Dirk J Kuik, Joost R M van der Sijp, Sybren Meijer,[...]. Liver Transpl 2004
51
Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases.
J M Leiper, J Santa Maria, A Chubb, R J MacAllister, I G Charles, G S Whitley, P Vallance. Biochem J 1999
J M Leiper, J Santa Maria, A Chubb, R J MacAllister, I G Charles, G S Whitley, P Vallance. Biochem J 1999
18
S-nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolase.
James Leiper, Judith Murray-Rust, Neil McDonald, Patrick Vallance. Proc Natl Acad Sci U S A 2002
James Leiper, Judith Murray-Rust, Neil McDonald, Patrick Vallance. Proc Natl Acad Sci U S A 2002
18
Inflammation is an important determinant of levels of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA) in acute liver failure.
Rajeshwar P Mookerjee, R Neil Dalton, Nathan A Davies, Stephen J Hodges, Charles Turner, Roger Williams, Rajiv Jalan. Liver Transpl 2007
Rajeshwar P Mookerjee, R Neil Dalton, Nathan A Davies, Stephen J Hodges, Charles Turner, Roger Williams, Rajiv Jalan. Liver Transpl 2007
31
Detection of NG,NG-dimethylarginine dimethylaminohydrolase in the nitric oxide-generating systems of rats using monoclonal antibody.
M Kimoto, H Tsuji, T Ogawa, K Sasaoka. Arch Biochem Biophys 1993
M Kimoto, H Tsuji, T Ogawa, K Sasaoka. Arch Biochem Biophys 1993
17
17
Endogenous dimethylarginine as an inhibitor of nitric oxide synthesis.
P Vallance, A Leone, A Calver, J Collier, S Moncada. J Cardiovasc Pharmacol 1992
P Vallance, A Leone, A Calver, J Collier, S Moncada. J Cardiovasc Pharmacol 1992
16
LDL cholesterol upregulates synthesis of asymmetrical dimethylarginine in human endothelial cells: involvement of S-adenosylmethionine-dependent methyltransferases.
R H Böger, K Sydow, J Borlak, T Thum, H Lenzen, B Schubert, D Tsikas, S M Bode-Böger. Circ Res 2000
R H Böger, K Sydow, J Borlak, T Thum, H Lenzen, B Schubert, D Tsikas, S M Bode-Böger. Circ Res 2000
16
The clinical significance of asymmetric dimethylarginine.
Michiel P C Siroen, Tom Teerlink, Robert J Nijveldt, Hubert A Prins, Milan C Richir, Paul A M van Leeuwen. Annu Rev Nutr 2006
Michiel P C Siroen, Tom Teerlink, Robert J Nijveldt, Hubert A Prins, Milan C Richir, Paul A M van Leeuwen. Annu Rev Nutr 2006
16
Purification and properties of a new enzyme, NG,NG-dimethylarginine dimethylaminohydrolase, from rat kidney.
T Ogawa, M Kimoto, K Sasaoka. J Biol Chem 1989
T Ogawa, M Kimoto, K Sasaoka. J Biol Chem 1989
15
Cardiovascular effects of systemic nitric oxide synthase inhibition with asymmetrical dimethylarginine in humans.
Jan T Kielstein, Burcu Impraim, Solveig Simmel, Stefanie M Bode-Böger, Dimitrios Tsikas, Jürgen C Frölich, Marius M Hoeper, Hermann Haller, Danilo Fliser. Circulation 2004
Jan T Kielstein, Burcu Impraim, Solveig Simmel, Stefanie M Bode-Böger, Dimitrios Tsikas, Jürgen C Frölich, Marius M Hoeper, Hermann Haller, Danilo Fliser. Circulation 2004
15
Isoform-specific regulation by N(G),N(G)-dimethylarginine dimethylaminohydrolase of rat serum asymmetric dimethylarginine and vascular endothelium-derived relaxing factor/NO.
Dan Wang, Pritmohinder S Gill, Tinatin Chabrashvili, Maristela L Onozato, Julie Raggio, Margarida Mendonca, Kathryn Dennehy, Min Li, Paul Modlinger, James Leiper,[...]. Circ Res 2007
Dan Wang, Pritmohinder S Gill, Tinatin Chabrashvili, Maristela L Onozato, Julie Raggio, Margarida Mendonca, Kathryn Dennehy, Min Li, Paul Modlinger, James Leiper,[...]. Circ Res 2007
15
Cellular ADMA: regulation and action.
Tom Teerlink, Zaiming Luo, Fredrik Palm, Christopher S Wilcox. Pharmacol Res 2009
Tom Teerlink, Zaiming Luo, Fredrik Palm, Christopher S Wilcox. Pharmacol Res 2009
15
The asymmetrical dimethylarginine (ADMA)-multiple organ failure hypothesis.
R J Nijveldt, T Teerlink, P A M van Leeuwen. Clin Nutr 2003
R J Nijveldt, T Teerlink, P A M van Leeuwen. Clin Nutr 2003
20
Determination of dimethylarginine dimethylaminohydrolase activity in the kidney.
Y-L Tain, C Baylis. Kidney Int 2007
Y-L Tain, C Baylis. Kidney Int 2007
20
Colocalization of demethylating enzymes and NOS and functional effects of methylarginines in rat kidney.
A Tojo, W J Welch, V Bremer, M Kimoto, K Kimura, M Omata, T Ogawa, P Vallance, C S Wilcox. Kidney Int 1997
A Tojo, W J Welch, V Bremer, M Kimoto, K Kimura, M Omata, T Ogawa, P Vallance, C S Wilcox. Kidney Int 1997
13
Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor.
Markus C Stühlinger, Fahim Abbasi, James W Chu, Cindy Lamendola, Tracey L McLaughlin, John P Cooke, Gerald M Reaven, Philip S Tsao. JAMA 2002
Markus C Stühlinger, Fahim Abbasi, James W Chu, Cindy Lamendola, Tracey L McLaughlin, John P Cooke, Gerald M Reaven, Philip S Tsao. JAMA 2002
13
A role for asymmetric dimethylarginine in the pathophysiology of portal hypertension in rats with biliary cirrhosis.
Wim Laleman, Anita Omasta, Marc Van de Casteele, Marcel Zeegers, Ingrid Vander Elst, Lien Van Landeghem, Tamara Severi, Jos van Pelt, Tania Roskams, Johan Fevery,[...]. Hepatology 2005
Wim Laleman, Anita Omasta, Marc Van de Casteele, Marcel Zeegers, Ingrid Vander Elst, Lien Van Landeghem, Tamara Severi, Jos van Pelt, Tania Roskams, Johan Fevery,[...]. Hepatology 2005
22
Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: genetic and physiological evidence.
Hayan Dayoub, Vinod Achan, Shanthi Adimoolam, Johannes Jacobi, Marcus C Stuehlinger, Bing-yin Wang, Philip S Tsao, M Kimoto, Patrick Vallance, Andrew J Patterson,[...]. Circulation 2003
Hayan Dayoub, Vinod Achan, Shanthi Adimoolam, Johannes Jacobi, Marcus C Stuehlinger, Bing-yin Wang, Philip S Tsao, M Kimoto, Patrick Vallance, Andrew J Patterson,[...]. Circulation 2003
13
Disruption of methylarginine metabolism impairs vascular homeostasis.
James Leiper, Manasi Nandi, Belen Torondel, Judith Murray-Rust, Mohammed Malaki, Bernard O'Hara, Sharon Rossiter, Shelagh Anthony, Melanie Madhani, David Selwood,[...]. Nat Med 2007
James Leiper, Manasi Nandi, Belen Torondel, Judith Murray-Rust, Mohammed Malaki, Bernard O'Hara, Sharon Rossiter, Shelagh Anthony, Melanie Madhani, David Selwood,[...]. Nat Med 2007
13
Net renal extraction of asymmetrical (ADMA) and symmetrical (SDMA) dimethylarginine in fasting humans.
Robert J Nijveldt, Paul A M Van Leeuwen, Coen Van Guldener, Coen D A Stehouwer, Jan A Rauwerda, Tom Teerlink. Nephrol Dial Transplant 2002
Robert J Nijveldt, Paul A M Van Leeuwen, Coen Van Guldener, Coen D A Stehouwer, Jan A Rauwerda, Tom Teerlink. Nephrol Dial Transplant 2002
14
Determination of arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in human plasma and other biological samples by high-performance liquid chromatography.
Tom Teerlink, Robert J Nijveldt, Sigrid de Jong, Paul A M van Leeuwen. Anal Biochem 2002
Tom Teerlink, Robert J Nijveldt, Sigrid de Jong, Paul A M van Leeuwen. Anal Biochem 2002
12
Accumulation of symmetric dimethylarginine in hepatorenal syndrome.
Paloma Lluch, Maria D Mauricio, José M Vila, Gloria Segarra, Pascual Medina, Juan A Del Olmo, José M Rodrigo, Miguel A Serra. Exp Biol Med (Maywood) 2006
Paloma Lluch, Maria D Mauricio, José M Vila, Gloria Segarra, Pascual Medina, Juan A Del Olmo, José M Rodrigo, Miguel A Serra. Exp Biol Med (Maywood) 2006
25
Biological significance of endogenous methylarginines that inhibit nitric oxide synthases.
J Leiper, P Vallance. Cardiovasc Res 1999
J Leiper, P Vallance. Cardiovasc Res 1999
12
Structural insights into the hydrolysis of cellular nitric oxide synthase inhibitors by dimethylarginine dimethylaminohydrolase.
J Murray-Rust, J Leiper, M McAlister, J Phelan, S Tilley, J Santa Maria, P Vallance, N McDonald. Nat Struct Biol 2001
J Murray-Rust, J Leiper, M McAlister, J Phelan, S Tilley, J Santa Maria, P Vallance, N McDonald. Nat Struct Biol 2001
12
Evidence for the pathophysiological role of endogenous methylarginines in regulation of endothelial NO production and vascular function.
Arturo J Cardounel, Hongmei Cui, Alexandre Samouilov, Wesley Johnson, Patrick Kearns, Ah-Lim Tsai, Vladomir Berka, Jay L Zweier. J Biol Chem 2007
Arturo J Cardounel, Hongmei Cui, Alexandre Samouilov, Wesley Johnson, Patrick Kearns, Ah-Lim Tsai, Vladomir Berka, Jay L Zweier. J Biol Chem 2007
12
Asymmetric dimethylarginine and the risk of cardiovascular events and death in patients with coronary artery disease: results from the AtheroGene Study.
Renate Schnabel, Stefan Blankenberg, Edith Lubos, Karl J Lackner, Hans J Rupprecht, Christine Espinola-Klein, Nicole Jachmann, Felix Post, Dirk Peetz, Christoph Bickel,[...]. Circ Res 2005
Renate Schnabel, Stefan Blankenberg, Edith Lubos, Karl J Lackner, Hans J Rupprecht, Christine Espinola-Klein, Nicole Jachmann, Felix Post, Dirk Peetz, Christoph Bickel,[...]. Circ Res 2005
11
11
Endogenous nitric oxide synthase inhibitor: a novel marker of atherosclerosis.
H Miyazaki, H Matsuoka, J P Cooke, M Usui, S Ueda, S Okuda, T Imaizumi. Circulation 1999
H Miyazaki, H Matsuoka, J P Cooke, M Usui, S Ueda, S Okuda, T Imaizumi. Circulation 1999
11
Chromosomal localization, gene structure, and expression pattern of DDAH1: comparison with DDAH2 and implications for evolutionary origins.
C T Tran, M F Fox, P Vallance, J M Leiper. Genomics 2000
C T Tran, M F Fox, P Vallance, J M Leiper. Genomics 2000
11
Regulation of nitric oxide synthesis by dimethylarginine dimethylaminohydrolase.
R J MacAllister, H Parry, M Kimoto, T Ogawa, R J Russell, H Hodson, G S Whitley, P Vallance. Br J Pharmacol 1996
R J MacAllister, H Parry, M Kimoto, T Ogawa, R J Russell, H Hodson, G S Whitley, P Vallance. Br J Pharmacol 1996
11
Symmetric dimethylarginine (SDMA) as endogenous marker of renal function--a meta-analysis.
Jan T Kielstein, Shelley R Salpeter, Stefanie M Bode-Boeger, John P Cooke, Danilo Fliser. Nephrol Dial Transplant 2006
Jan T Kielstein, Shelley R Salpeter, Stefanie M Bode-Boeger, John P Cooke, Danilo Fliser. Nephrol Dial Transplant 2006
11
Reduced urinary excretion of nitric oxide metabolites and increased plasma levels of asymmetric dimethylarginine in men with essential hypertension.
A Surdacki, M Nowicki, J Sandmann, D Tsikas, R H Boeger, S M Bode-Boeger, O Kruszelnicka-Kwiatkowska, F Kokot, J S Dubiel, J C Froelich. J Cardiovasc Pharmacol 1999
A Surdacki, M Nowicki, J Sandmann, D Tsikas, R H Boeger, S M Bode-Boeger, O Kruszelnicka-Kwiatkowska, F Kokot, J S Dubiel, J C Froelich. J Cardiovasc Pharmacol 1999
11
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.