Chris Zarow, Scott A Lyness, James A Mortimer, Helena C Chui. Arch Neurol 2003
Times Cited: 628
Times Cited: 628
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Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease.
Sarah C Kelly, Bin He, Sylvia E Perez, Stephen D Ginsberg, Elliott J Mufson, Scott E Counts. Acta Neuropathol Commun 2017
Sarah C Kelly, Bin He, Sylvia E Perez, Stephen D Ginsberg, Elliott J Mufson, Scott E Counts. Acta Neuropathol Commun 2017
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Locus coeruleus volume and cell population changes during Alzheimer's disease progression: A stereological study in human postmortem brains with potential implication for early-stage biomarker discovery.
Panos Theofilas, Alexander J Ehrenberg, Sara Dunlop, Ana T Di Lorenzo Alho, Austin Nguy, Renata Elaine Paraizo Leite, Roberta Diehl Rodriguez, Maria B Mejia, Claudia K Suemoto, Renata Eloah De Lucena Ferretti-Rebustini,[...]. Alzheimers Dement 2017
Panos Theofilas, Alexander J Ehrenberg, Sara Dunlop, Ana T Di Lorenzo Alho, Austin Nguy, Renata Elaine Paraizo Leite, Roberta Diehl Rodriguez, Maria B Mejia, Claudia K Suemoto, Renata Eloah De Lucena Ferretti-Rebustini,[...]. Alzheimers Dement 2017
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Stages of the pathologic process in Alzheimer disease: age categories from 1 to 100 years.
Heiko Braak, Dietmar R Thal, Estifanos Ghebremedhin, Kelly Del Tredici. J Neuropathol Exp Neurol 2011
Heiko Braak, Dietmar R Thal, Estifanos Ghebremedhin, Kelly Del Tredici. J Neuropathol Exp Neurol 2011
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Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases.
Matthew J Betts, Evgeniya Kirilina, Maria C G Otaduy, Dimo Ivanov, Julio Acosta-Cabronero, Martina F Callaghan, Christian Lambert, Arturo Cardenas-Blanco, Kerrin Pine, Luca Passamonti,[...]. Brain 2019
Matthew J Betts, Evgeniya Kirilina, Maria C G Otaduy, Dimo Ivanov, Julio Acosta-Cabronero, Martina F Callaghan, Christian Lambert, Arturo Cardenas-Blanco, Kerrin Pine, Luca Passamonti,[...]. Brain 2019
22
The locus coeruleus-noradrenergic system: modulation of behavioral state and state-dependent cognitive processes.
Craig W Berridge, Barry D Waterhouse. Brain Res Brain Res Rev 2003
Craig W Berridge, Barry D Waterhouse. Brain Res Brain Res Rev 2003
21
Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease.
Aneta Grudzien, Pamela Shaw, Sandra Weintraub, Eileen Bigio, Deborah C Mash, M Marsel Mesulam. Neurobiol Aging 2007
Aneta Grudzien, Pamela Shaw, Sandra Weintraub, Eileen Bigio, Deborah C Mash, M Marsel Mesulam. Neurobiol Aging 2007
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Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.
Michael T Heneka, Fabian Nadrigny, Tommy Regen, Ana Martinez-Hernandez, Lucia Dumitrescu-Ozimek, Dick Terwel, Daniel Jardanhazi-Kurutz, Jochen Walter, Frank Kirchhoff, Uwe-Karsten Hanisch,[...]. Proc Natl Acad Sci U S A 2010
Michael T Heneka, Fabian Nadrigny, Tommy Regen, Ana Martinez-Hernandez, Lucia Dumitrescu-Ozimek, Dick Terwel, Daniel Jardanhazi-Kurutz, Jochen Walter, Frank Kirchhoff, Uwe-Karsten Hanisch,[...]. Proc Natl Acad Sci U S A 2010
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Staging of brain pathology related to sporadic Parkinson's disease.
Heiko Braak, Kelly Del Tredici, Udo Rüb, Rob A I de Vos, Ernst N H Jansen Steur, Eva Braak. Neurobiol Aging 2003
Heiko Braak, Kelly Del Tredici, Udo Rüb, Rob A I de Vos, Ernst N H Jansen Steur, Eva Braak. Neurobiol Aging 2003
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Noradrenergic mechanisms in neurodegenerative diseases: a theory.
Marc R Marien, Francis C Colpaert, Alan C Rosenquist. Brain Res Brain Res Rev 2004
Marc R Marien, Francis C Colpaert, Alan C Rosenquist. Brain Res Brain Res Rev 2004
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Disease-specific patterns of locus coeruleus cell loss.
D C German, K F Manaye, C L White, D J Woodward, D D McIntire, W K Smith, R N Kalaria, D M Mann. Ann Neurol 1992
D C German, K F Manaye, C L White, D J Woodward, D D McIntire, W K Smith, R N Kalaria, D M Mann. Ann Neurol 1992
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Organization of the locus coeruleus-norepinephrine system.
Lindsay A Schwarz, Liqun Luo. Curr Biol 2015
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Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice.
Michael T Heneka, Mutiah Ramanathan, Andreas H Jacobs, Lucia Dumitrescu-Ozimek, Andras Bilkei-Gorzo, Thomas Debeir, Magdalena Sastre, Norbert Galldiks, Andreas Zimmer, Mathias Hoehn,[...]. J Neurosci 2006
Michael T Heneka, Mutiah Ramanathan, Andreas H Jacobs, Lucia Dumitrescu-Ozimek, Andras Bilkei-Gorzo, Thomas Debeir, Magdalena Sastre, Norbert Galldiks, Andreas Zimmer, Mathias Hoehn,[...]. J Neurosci 2006
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Norepinephrine deficiency in Parkinson's disease: the case for noradrenergic enhancement.
Alberto J Espay, Peter A LeWitt, Horacio Kaufmann. Mov Disord 2014
Alberto J Espay, Peter A LeWitt, Horacio Kaufmann. Mov Disord 2014
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Neuromelanin magnetic resonance imaging of locus ceruleus and substantia nigra in Parkinson's disease.
Makoto Sasaki, Eri Shibata, Koujiro Tohyama, Junko Takahashi, Kotaro Otsuka, Kuniaki Tsuchiya, Satoshi Takahashi, Shigeru Ehara, Yasuo Terayama, Akio Sakai. Neuroreport 2006
Makoto Sasaki, Eri Shibata, Koujiro Tohyama, Junko Takahashi, Kotaro Otsuka, Kuniaki Tsuchiya, Satoshi Takahashi, Shigeru Ehara, Yasuo Terayama, Akio Sakai. Neuroreport 2006
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Causes, consequences, and cures for neuroinflammation mediated via the locus coeruleus: noradrenergic signaling system.
Douglas L Feinstein, Sergey Kalinin, David Braun. J Neurochem 2016
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Long Road to Ruin: Noradrenergic Dysfunction in Neurodegenerative Disease.
David Weinshenker. Trends Neurosci 2018
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An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance.
Gary Aston-Jones, Jonathan D Cohen. Annu Rev Neurosci 2005
Gary Aston-Jones, Jonathan D Cohen. Annu Rev Neurosci 2005
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Alterations in catecholamine neurons of the locus coeruleus in senile dementia of the Alzheimer type and in Parkinson's disease with and without dementia and depression.
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Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease.
Sergey Kalinin, Vitaliy Gavrilyuk, Paul E Polak, Robert Vasser, Jie Zhao, Michael T Heneka, Douglas L Feinstein. Neurobiol Aging 2007
Sergey Kalinin, Vitaliy Gavrilyuk, Paul E Polak, Robert Vasser, Jie Zhao, Michael T Heneka, Douglas L Feinstein. Neurobiol Aging 2007
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Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer's disease Braak stages: a quantitative study in humans.
Panos Theofilas, Alexander J Ehrenberg, Austin Nguy, Julia M Thackrey, Sara Dunlop, Maria B Mejia, Ana T Alho, Renata Elaine Paraizo Leite, Roberta Diehl Rodriguez, Claudia K Suemoto,[...]. Neurobiol Aging 2018
Panos Theofilas, Alexander J Ehrenberg, Austin Nguy, Julia M Thackrey, Sara Dunlop, Maria B Mejia, Ana T Alho, Renata Elaine Paraizo Leite, Roberta Diehl Rodriguez, Claudia K Suemoto,[...]. Neurobiol Aging 2018
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Cell loss in the locus coeruleus in senile dementia of Alzheimer type.
B E Tomlinson, D Irving, G Blessed. J Neurol Sci 1981
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The pathological process underlying Alzheimer's disease in individuals under thirty.
Heiko Braak, Kelly Del Tredici. Acta Neuropathol 2011
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Locus coeruleus at asymptomatic early and middle Braak stages of neurofibrillary tangle pathology.
P Andrés-Benito, V Fernández-Dueñas, M Carmona, L A Escobar, B Torrejón-Escribano, E Aso, F Ciruela, I Ferrer. Neuropathol Appl Neurobiol 2017
P Andrés-Benito, V Fernández-Dueñas, M Carmona, L A Escobar, B Torrejón-Escribano, E Aso, F Ciruela, I Ferrer. Neuropathol Appl Neurobiol 2017
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The Locus Coeruleus: Essential for Maintaining Cognitive Function and the Aging Brain.
Mara Mather, Carolyn W Harley. Trends Cogn Sci 2016
Mara Mather, Carolyn W Harley. Trends Cogn Sci 2016
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In vivo visualization of age-related differences in the locus coeruleus.
Kathy Y Liu, Julio Acosta-Cabronero, Arturo Cardenas-Blanco, Clare Loane, Alex J Berry, Matthew J Betts, Rogier A Kievit, Richard N Henson, Emrah Düzel, Robert Howard,[...]. Neurobiol Aging 2019
Kathy Y Liu, Julio Acosta-Cabronero, Arturo Cardenas-Blanco, Clare Loane, Alex J Berry, Matthew J Betts, Rogier A Kievit, Richard N Henson, Emrah Düzel, Robert Howard,[...]. Neurobiol Aging 2019
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Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease.
Fabio A Zucca, Juan Segura-Aguilar, Emanuele Ferrari, Patricia Muñoz, Irmgard Paris, David Sulzer, Tadeusz Sarna, Luigi Casella, Luigi Zecca. Prog Neurobiol 2017
Fabio A Zucca, Juan Segura-Aguilar, Emanuele Ferrari, Patricia Muñoz, Irmgard Paris, David Sulzer, Tadeusz Sarna, Luigi Casella, Luigi Zecca. Prog Neurobiol 2017
10
Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus.
Seong Su Kang, Xia Liu, Eun Hee Ahn, Jie Xiang, Fredric P Manfredsson, Xifei Yang, Hongbo R Luo, L Cameron Liles, David Weinshenker, Keqiang Ye. J Clin Invest 2020
Seong Su Kang, Xia Liu, Eun Hee Ahn, Jie Xiang, Fredric P Manfredsson, Xifei Yang, Hongbo R Luo, L Cameron Liles, David Weinshenker, Keqiang Ye. J Clin Invest 2020
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Noradrenergic regulation of inflammatory gene expression in brain.
Douglas L Feinstein, Michael T Heneka, Vitaliy Gavrilyuk, Cinzia Dello Russo, Guy Weinberg, Elena Galea. Neurochem Int 2002
Douglas L Feinstein, Michael T Heneka, Vitaliy Gavrilyuk, Cinzia Dello Russo, Guy Weinberg, Elena Galea. Neurochem Int 2002
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The role of the locus coeruleus in the development of Parkinson's disease.
M Gesi, P Soldani, F S Giorgi, A Santinami, I Bonaccorsi, F Fornai. Neurosci Biobehav Rev 2000
M Gesi, P Soldani, F S Giorgi, A Santinami, I Bonaccorsi, F Fornai. Neurosci Biobehav Rev 2000
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Depression in Parkinson's disease: loss of dopamine and noradrenaline innervation in the limbic system.
Philippe Remy, Miroslava Doder, Andrew Lees, Nora Turjanski, David Brooks. Brain 2005
Philippe Remy, Miroslava Doder, Andrew Lees, Nora Turjanski, David Brooks. Brain 2005
9
Absolute number and size of pigmented locus coeruleus neurons in young and aged individuals.
P R Mouton, B Pakkenberg, H J Gundersen, D L Price. J Chem Neuroanat 1994
P R Mouton, B Pakkenberg, H J Gundersen, D L Price. J Chem Neuroanat 1994
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The locus ceruleus norepinephrine system: functional organization and potential clinical significance.
Eduardo E Benarroch. Neurology 2009
Eduardo E Benarroch. Neurology 2009
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Neuromelanin marks the spot: identifying a locus coeruleus biomarker of cognitive reserve in healthy aging.
David V Clewett, Tae-Ho Lee, Steven Greening, Allison Ponzio, Eshed Margalit, Mara Mather. Neurobiol Aging 2016
David V Clewett, Tae-Ho Lee, Steven Greening, Allison Ponzio, Eshed Margalit, Mara Mather. Neurobiol Aging 2016
10
Early neurone loss in Alzheimer's disease: cortical or subcortical?
Thomas Arendt, Martina K Brückner, Markus Morawski, Carsten Jäger, Hermann-Josef Gertz. Acta Neuropathol Commun 2015
Thomas Arendt, Martina K Brückner, Markus Morawski, Carsten Jäger, Hermann-Josef Gertz. Acta Neuropathol Commun 2015
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Monoaminergic neuropathology in Alzheimer's disease.
Goran Šimić, Mirjana Babić Leko, Selina Wray, Charles R Harrington, Ivana Delalle, Nataša Jovanov-Milošević, Danira Bažadona, Luc Buée, Rohan de Silva, Giuseppe Di Giovanni,[...]. Prog Neurobiol 2017
Goran Šimić, Mirjana Babić Leko, Selina Wray, Charles R Harrington, Ivana Delalle, Nataša Jovanov-Milošević, Danira Bažadona, Luc Buée, Rohan de Silva, Giuseppe Di Giovanni,[...]. Prog Neurobiol 2017
9
High-resolution in vivo imaging of human locus coeruleus by magnetization transfer MRI at 3T and 7T.
Nikos Priovoulos, Heidi I L Jacobs, Dimo Ivanov, Kâmil Uludağ, Frans R J Verhey, Benedikt A Poser. Neuroimage 2018
Nikos Priovoulos, Heidi I L Jacobs, Dimo Ivanov, Kâmil Uludağ, Frans R J Verhey, Benedikt A Poser. Neuroimage 2018
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In vivo MRI assessment of the human locus coeruleus along its rostrocaudal extent in young and older adults.
Matthew J Betts, Arturo Cardenas-Blanco, Martin Kanowski, Frank Jessen, Emrah Düzel. Neuroimage 2017
Matthew J Betts, Arturo Cardenas-Blanco, Martin Kanowski, Frank Jessen, Emrah Düzel. Neuroimage 2017
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Detection of changes in the locus coeruleus in patients with mild cognitive impairment and Alzheimer's disease: high-resolution fast spin-echo T1-weighted imaging.
Junko Takahashi, Toshihide Shibata, Makoto Sasaki, Masako Kudo, Hisashi Yanezawa, Satoko Obara, Kohsuke Kudo, Kenji Ito, Fumio Yamashita, Yasuo Terayama. Geriatr Gerontol Int 2015
Junko Takahashi, Toshihide Shibata, Makoto Sasaki, Masako Kudo, Hisashi Yanezawa, Satoko Obara, Kohsuke Kudo, Kenji Ito, Fumio Yamashita, Yasuo Terayama. Geriatr Gerontol Int 2015
17
Chemogenetic locus coeruleus activation restores reversal learning in a rat model of Alzheimer's disease.
Jacki M Rorabaugh, Termpanit Chalermpalanupap, Christian A Botz-Zapp, Vanessa M Fu, Natalie A Lembeck, Robert M Cohen, David Weinshenker. Brain 2017
Jacki M Rorabaugh, Termpanit Chalermpalanupap, Christian A Botz-Zapp, Vanessa M Fu, Natalie A Lembeck, Robert M Cohen, David Weinshenker. Brain 2017
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Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part I: principles of functional organisation.
E R Samuels, E Szabadi. Curr Neuropharmacol 2008
E R Samuels, E Szabadi. Curr Neuropharmacol 2008
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Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part II: physiological and pharmacological manipulations and pathological alterations of locus coeruleus activity in humans.
E R Samuels, E Szabadi. Curr Neuropharmacol 2008
E R Samuels, E Szabadi. Curr Neuropharmacol 2008
8
Quantifying the accretion of hyperphosphorylated tau in the locus coeruleus and dorsal raphe nucleus: the pathological building blocks of early Alzheimer's disease.
A J Ehrenberg, A K Nguy, P Theofilas, S Dunlop, C K Suemoto, A T Di Lorenzo Alho, R P Leite, R Diehl Rodriguez, M B Mejia, U Rüb,[...]. Neuropathol Appl Neurobiol 2017
A J Ehrenberg, A K Nguy, P Theofilas, S Dunlop, C K Suemoto, A T Di Lorenzo Alho, R P Leite, R Diehl Rodriguez, M B Mejia, U Rüb,[...]. Neuropathol Appl Neurobiol 2017
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Dysfunction of the locus coeruleus-norepinephrine system and related circuitry in Parkinson's disease-related dementia.
Kelly Del Tredici, Heiko Braak. J Neurol Neurosurg Psychiatry 2013
Kelly Del Tredici, Heiko Braak. J Neurol Neurosurg Psychiatry 2013
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Noradrenaline activation of neurotrophic pathways protects against neuronal amyloid toxicity.
Scott E Counts, Elliott J Mufson. J Neurochem 2010
Scott E Counts, Elliott J Mufson. J Neurochem 2010
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The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging.
Luigi Zecca, Antonella Stroppolo, Alberto Gatti, Davide Tampellini, Marco Toscani, Mario Gallorini, Giuseppe Giaveri, Paolo Arosio, Paolo Santambrogio, Ruggero G Fariello,[...]. Proc Natl Acad Sci U S A 2004
Luigi Zecca, Antonella Stroppolo, Alberto Gatti, Davide Tampellini, Marco Toscani, Mario Gallorini, Giuseppe Giaveri, Paolo Arosio, Paolo Santambrogio, Ruggero G Fariello,[...]. Proc Natl Acad Sci U S A 2004
8
Noradrenergic dysfunction accelerates LPS-elicited inflammation-related ascending sequential neurodegeneration and deficits in non-motor/motor functions.
Sheng Song, Qingshan Wang, Lulu Jiang, Esteban Oyarzabal, Natallia V Riddick, Belinda Wilson, Sheryl S Moy, Yen-Yu Ian Shih, Jau-Shyong Hong. Brain Behav Immun 2019
Sheng Song, Qingshan Wang, Lulu Jiang, Esteban Oyarzabal, Natallia V Riddick, Belinda Wilson, Sheryl S Moy, Yen-Yu Ian Shih, Jau-Shyong Hong. Brain Behav Immun 2019
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In vivo mapping of the human locus coeruleus.
Noam I Keren, Carl T Lozar, Kelly C Harris, Paul S Morgan, Mark A Eckert. Neuroimage 2009
Noam I Keren, Carl T Lozar, Kelly C Harris, Paul S Morgan, Mark A Eckert. Neuroimage 2009
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Turning on the Light Within: Subcortical Nuclei of the Isodentritic Core and their Role in Alzheimer's Disease Pathogenesis.
Panos Theofilas, Sara Dunlop, Helmut Heinsen, Lea Tenenholz Grinberg. J Alzheimers Dis 2015
Panos Theofilas, Sara Dunlop, Helmut Heinsen, Lea Tenenholz Grinberg. J Alzheimers Dis 2015
18
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.