Irene M Ward, Kay Minn, Jan van Deursen, Junjie Chen. Mol Cell Biol 2003
Times Cited: 313
Times Cited: 313
Times Cited
Times Co-cited
Similarity
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
Samuel F Bunting, Elsa Callén, Nancy Wong, Hua-Tang Chen, Federica Polato, Amanda Gunn, Anne Bothmer, Niklas Feldhahn, Oscar Fernandez-Capetillo, Liu Cao,[...]. Cell 2010
Samuel F Bunting, Elsa Callén, Nancy Wong, Hua-Tang Chen, Federica Polato, Amanda Gunn, Anne Bothmer, Niklas Feldhahn, Oscar Fernandez-Capetillo, Liu Cao,[...]. Cell 2010
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53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.
Peter Bouwman, Amal Aly, Jose M Escandell, Mark Pieterse, Jirina Bartkova, Hanneke van der Gulden, Sanne Hiddingh, Maria Thanasoula, Atul Kulkarni, Qifeng Yang,[...]. Nat Struct Mol Biol 2010
Peter Bouwman, Amal Aly, Jose M Escandell, Mark Pieterse, Jirina Bartkova, Hanneke van der Gulden, Sanne Hiddingh, Maria Thanasoula, Atul Kulkarni, Qifeng Yang,[...]. Nat Struct Mol Biol 2010
26
A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice.
Cristina Escribano-Díaz, Alexandre Orthwein, Amélie Fradet-Turcotte, Mengtan Xing, Jordan T F Young, Ján Tkáč, Michael A Cook, Adam P Rosebrock, Meagan Munro, Marella D Canny,[...]. Mol Cell 2013
Cristina Escribano-Díaz, Alexandre Orthwein, Amélie Fradet-Turcotte, Mengtan Xing, Jordan T F Young, Ján Tkáč, Michael A Cook, Adam P Rosebrock, Meagan Munro, Marella D Canny,[...]. Mol Cell 2013
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RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.
J Ross Chapman, Patricia Barral, Jean-Baptiste Vannier, Valérie Borel, Martin Steger, Antonia Tomas-Loba, Alessandro A Sartori, Ian R Adams, Facundo D Batista, Simon J Boulton. Mol Cell 2013
J Ross Chapman, Patricia Barral, Jean-Baptiste Vannier, Valérie Borel, Martin Steger, Antonia Tomas-Loba, Alessandro A Sartori, Ian R Adams, Facundo D Batista, Simon J Boulton. Mol Cell 2013
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Double-strand break repair: 53BP1 comes into focus.
Stephanie Panier, Simon J Boulton. Nat Rev Mol Cell Biol 2014
Stephanie Panier, Simon J Boulton. Nat Rev Mol Cell Biol 2014
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53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark.
Amélie Fradet-Turcotte, Marella D Canny, Cristina Escribano-Díaz, Alexandre Orthwein, Charles C Y Leung, Hao Huang, Marie-Claude Landry, Julianne Kitevski-LeBlanc, Sylvie M Noordermeer, Frank Sicheri,[...]. Nature 2013
Amélie Fradet-Turcotte, Marella D Canny, Cristina Escribano-Díaz, Alexandre Orthwein, Charles C Y Leung, Hao Huang, Marie-Claude Landry, Julianne Kitevski-LeBlanc, Sylvie M Noordermeer, Frank Sicheri,[...]. Nature 2013
23
53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.
John P Manis, Julio C Morales, Zhenfang Xia, Jeffery L Kutok, Frederick W Alt, Phillip B Carpenter. Nat Immunol 2004
John P Manis, Julio C Morales, Zhenfang Xia, Jeffery L Kutok, Frederick W Alt, Phillip B Carpenter. Nat Immunol 2004
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53BP1 regulates DSB repair using Rif1 to control 5' end resection.
Michal Zimmermann, Francisca Lottersberger, Sara B Buonomo, Agnel Sfeir, Titia de Lange. Science 2013
Michal Zimmermann, Francisca Lottersberger, Sara B Buonomo, Agnel Sfeir, Titia de Lange. Science 2013
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53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility.
Nadya Dimitrova, Yi-Chun M Chen, David L Spector, Titia de Lange. Nature 2008
Nadya Dimitrova, Yi-Chun M Chen, David L Spector, Titia de Lange. Nature 2008
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Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.
Michela Di Virgilio, Elsa Callen, Arito Yamane, Wenzhu Zhang, Mila Jankovic, Alexander D Gitlin, Niklas Feldhahn, Wolfgang Resch, Thiago Y Oliveira, Brian T Chait,[...]. Science 2013
Michela Di Virgilio, Elsa Callen, Arito Yamane, Wenzhu Zhang, Mila Jankovic, Alexander D Gitlin, Niklas Feldhahn, Wolfgang Resch, Thiago Y Oliveira, Brian T Chait,[...]. Science 2013
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53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.
Elsa Callen, Michela Di Virgilio, Michael J Kruhlak, Maria Nieto-Soler, Nancy Wong, Hua-Tang Chen, Robert B Faryabi, Federica Polato, Margarida Santos, Linda M Starnes,[...]. Cell 2013
Elsa Callen, Michela Di Virgilio, Michael J Kruhlak, Maria Nieto-Soler, Nancy Wong, Hua-Tang Chen, Robert B Faryabi, Federica Polato, Margarida Santos, Linda M Starnes,[...]. Cell 2013
18
53BP1 is required for class switch recombination.
Irene M Ward, Bernardo Reina-San-Martin, Alexandru Olaru, Kay Minn, Koji Tamada, Julie S Lau, Marilia Cascalho, Lieping Chen, Andre Nussenzweig, Ferenc Livak,[...]. J Cell Biol 2004
Irene M Ward, Bernardo Reina-San-Martin, Alexandru Olaru, Kay Minn, Koji Tamada, Julie S Lau, Marilia Cascalho, Lieping Chen, Andre Nussenzweig, Ferenc Livak,[...]. J Cell Biol 2004
18
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair.
Maria Victoria Botuyan, Joseph Lee, Irene M Ward, Ja-Eun Kim, James R Thompson, Junjie Chen, Georges Mer. Cell 2006
Maria Victoria Botuyan, Joseph Lee, Irene M Ward, Ja-Eun Kim, James R Thompson, Junjie Chen, Georges Mer. Cell 2006
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p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks.
L B Schultz, N H Chehab, A Malikzay, T D Halazonetis. J Cell Biol 2000
L B Schultz, N H Chehab, A Malikzay, T D Halazonetis. J Cell Biol 2000
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RIF1 counteracts BRCA1-mediated end resection during DNA repair.
Lin Feng, Ka-Wing Fong, Jiadong Wang, Wenqi Wang, Junjie Chen. J Biol Chem 2013
Lin Feng, Ka-Wing Fong, Jiadong Wang, Wenqi Wang, Junjie Chen. J Biol Chem 2013
14
A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency.
Liu Cao, Xioaling Xu, Samuel F Bunting, Jie Liu, Rui-Hong Wang, Longyue L Cao, J Julie Wu, Tie-Nan Peng, Junjie Chen, Andre Nussenzweig,[...]. Mol Cell 2009
Liu Cao, Xioaling Xu, Samuel F Bunting, Jie Liu, Rui-Hong Wang, Longyue L Cao, J Julie Wu, Tie-Nan Peng, Junjie Chen, Andre Nussenzweig,[...]. Mol Cell 2009
14
The shieldin complex mediates 53BP1-dependent DNA repair.
Sylvie M Noordermeer, Salomé Adam, Dheva Setiaputra, Marco Barazas, Stephen J Pettitt, Alexanda K Ling, Michele Olivieri, Alejandro Álvarez-Quilón, Nathalie Moatti, Michal Zimmermann,[...]. Nature 2018
Sylvie M Noordermeer, Salomé Adam, Dheva Setiaputra, Marco Barazas, Stephen J Pettitt, Alexanda K Ling, Michele Olivieri, Alejandro Álvarez-Quilón, Nathalie Moatti, Michal Zimmermann,[...]. Nature 2018
14
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway.
Michael R Lieber. Annu Rev Biochem 2010
Michael R Lieber. Annu Rev Biochem 2010
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Regulation of DNA end joining, resection, and immunoglobulin class switch recombination by 53BP1.
Anne Bothmer, Davide F Robbiani, Michela Di Virgilio, Samuel F Bunting, Isaac A Klein, Niklas Feldhahn, Jacqueline Barlow, Hua-Tang Chen, David Bosque, Elsa Callen,[...]. Mol Cell 2011
Anne Bothmer, Davide F Robbiani, Michela Di Virgilio, Samuel F Bunting, Isaac A Klein, Niklas Feldhahn, Jacqueline Barlow, Hua-Tang Chen, David Bosque, Elsa Callen,[...]. Mol Cell 2011
13
53BP1 facilitates long-range DNA end-joining during V(D)J recombination.
Simone Difilippantonio, Eric Gapud, Nancy Wong, Ching-Yu Huang, Grace Mahowald, Hua Tang Chen, Michael J Kruhlak, Elsa Callen, Ferenc Livak, Michel C Nussenzweig,[...]. Nature 2008
Simone Difilippantonio, Eric Gapud, Nancy Wong, Ching-Yu Huang, Grace Mahowald, Hua Tang Chen, Michael J Kruhlak, Elsa Callen, Ferenc Livak, Michel C Nussenzweig,[...]. Nature 2008
13
Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.
Harveer Dev, Ting-Wei Will Chiang, Chloe Lescale, Inge de Krijger, Alistair G Martin, Domenic Pilger, Julia Coates, Matylda Sczaniecka-Clift, Wenming Wei, Matthias Ostermaier,[...]. Nat Cell Biol 2018
Harveer Dev, Ting-Wei Will Chiang, Chloe Lescale, Inge de Krijger, Alistair G Martin, Domenic Pilger, Julia Coates, Matylda Sczaniecka-Clift, Wenming Wei, Matthias Ostermaier,[...]. Nat Cell Biol 2018
12
DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1.
Oscar Fernandez-Capetillo, Hua-Tang Chen, Arkady Celeste, Irene Ward, Peter J Romanienko, Julio C Morales, Kazuhito Naka, Zhenfang Xia, R Daniel Camerini-Otero, Noboru Motoyama,[...]. Nat Cell Biol 2002
Oscar Fernandez-Capetillo, Hua-Tang Chen, Arkady Celeste, Irene Ward, Peter J Romanienko, Julio C Morales, Kazuhito Naka, Zhenfang Xia, R Daniel Camerini-Otero, Noboru Motoyama,[...]. Nat Cell Biol 2002
11
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Hannah Farmer, Nuala McCabe, Christopher J Lord, Andrew N J Tutt, Damian A Johnson, Tobias B Richardson, Manuela Santarosa, Krystyna J Dillon, Ian Hickson, Charlotte Knights,[...]. Nature 2005
Hannah Farmer, Nuala McCabe, Christopher J Lord, Andrew N J Tutt, Damian A Johnson, Tobias B Richardson, Manuela Santarosa, Krystyna J Dillon, Ian Hickson, Charlotte Knights,[...]. Nature 2005
11
REV7 counteracts DNA double-strand break resection and affects PARP inhibition.
Guotai Xu, J Ross Chapman, Inger Brandsma, Jingsong Yuan, Martin Mistrik, Peter Bouwman, Jirina Bartkova, Ewa Gogola, Daniël Warmerdam, Marco Barazas,[...]. Nature 2015
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11
53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ.
Hind Ghezraoui, Catarina Oliveira, Jordan R Becker, Kirstin Bilham, Daniela Moralli, Consuelo Anzilotti, Roman Fischer, Mukta Deobagkar-Lele, Maria Sanchiz-Calvo, Elena Fueyo-Marcos,[...]. Nature 2018
Hind Ghezraoui, Catarina Oliveira, Jordan R Becker, Kirstin Bilham, Daniela Moralli, Consuelo Anzilotti, Roman Fischer, Mukta Deobagkar-Lele, Maria Sanchiz-Calvo, Elena Fueyo-Marcos,[...]. Nature 2018
11
Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination.
Jiangbo Tang, Nam Woo Cho, Gaofeng Cui, Erica M Manion, Niraj M Shanbhag, Maria Victoria Botuyan, Georges Mer, Roger A Greenberg. Nat Struct Mol Biol 2013
Jiangbo Tang, Nam Woo Cho, Gaofeng Cui, Erica M Manion, Niraj M Shanbhag, Maria Victoria Botuyan, Georges Mer, Roger A Greenberg. Nat Struct Mol Biol 2013
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53BP1, a mediator of the DNA damage checkpoint.
Bin Wang, Shuhei Matsuoka, Phillip B Carpenter, Stephen J Elledge. Science 2002
Bin Wang, Shuhei Matsuoka, Phillip B Carpenter, Stephen J Elledge. Science 2002
10
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins.
Niels Mailand, Simon Bekker-Jensen, Helene Faustrup, Fredrik Melander, Jiri Bartek, Claudia Lukas, Jiri Lukas. Cell 2007
Niels Mailand, Simon Bekker-Jensen, Helene Faustrup, Fredrik Melander, Jiri Bartek, Claudia Lukas, Jiri Lukas. Cell 2007
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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139.
E P Rogakou, D R Pilch, A H Orr, V S Ivanova, W M Bonner. J Biol Chem 1998
E P Rogakou, D R Pilch, A H Orr, V S Ivanova, W M Bonner. J Biol Chem 1998
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Two cellular proteins that bind to wild-type but not mutant p53.
K Iwabuchi, P L Bartel, B Li, R Marraccino, S Fields. Proc Natl Acad Sci U S A 1994
K Iwabuchi, P L Bartel, B Li, R Marraccino, S Fields. Proc Natl Acad Sci U S A 1994
9
9
Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability.
Julio C Morales, Zhenfang Xia, Tao Lu, Melissa B Aldrich, Bin Wang, Corina Rosales, Rodney E Kellems, Walter N Hittelman, Stephen J Elledge, Phillip B Carpenter. J Biol Chem 2003
Julio C Morales, Zhenfang Xia, Tao Lu, Melissa B Aldrich, Bin Wang, Corina Rosales, Rodney E Kellems, Walter N Hittelman, Stephen J Elledge, Phillip B Carpenter. J Biol Chem 2003
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RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins.
Carsten Doil, Niels Mailand, Simon Bekker-Jensen, Patrice Menard, Dorthe Helena Larsen, Rainer Pepperkok, Jan Ellenberg, Stephanie Panier, Daniel Durocher, Jiri Bartek,[...]. Cell 2009
Carsten Doil, Niels Mailand, Simon Bekker-Jensen, Patrice Menard, Dorthe Helena Larsen, Rainer Pepperkok, Jan Ellenberg, Stephanie Panier, Daniel Durocher, Jiri Bartek,[...]. Cell 2009
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The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage.
Grant S Stewart, Stephanie Panier, Kelly Townsend, Abdallah K Al-Hakim, Nadine K Kolas, Edward S Miller, Shinichiro Nakada, Jarkko Ylanko, Signe Olivarius, Megan Mendez,[...]. Cell 2009
Grant S Stewart, Stephanie Panier, Kelly Townsend, Abdallah K Al-Hakim, Nadine K Kolas, Edward S Miller, Shinichiro Nakada, Jarkko Ylanko, Signe Olivarius, Megan Mendez,[...]. Cell 2009
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RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly.
Michael S Y Huen, Robert Grant, Isaac Manke, Kay Minn, Xiaochun Yu, Michael B Yaffe, Junjie Chen. Cell 2007
Michael S Y Huen, Robert Grant, Isaac Manke, Kay Minn, Xiaochun Yu, Michael B Yaffe, Junjie Chen. Cell 2007
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The DNA damage response: making it safe to play with knives.
Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
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53BP1 Integrates DNA Repair and p53-Dependent Cell Fate Decisions via Distinct Mechanisms.
Raquel Cuella-Martin, Catarina Oliveira, Helen E Lockstone, Suzanne Snellenberg, Natalia Grolmusova, J Ross Chapman. Mol Cell 2016
Raquel Cuella-Martin, Catarina Oliveira, Helen E Lockstone, Suzanne Snellenberg, Natalia Grolmusova, J Ross Chapman. Mol Cell 2016
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53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in.
Zachary Mirman, Francisca Lottersberger, Hiroyuki Takai, Tatsuya Kibe, Yi Gong, Kaori Takai, Alessandro Bianchi, Michal Zimmermann, Daniel Durocher, Titia de Lange. Nature 2018
Zachary Mirman, Francisca Lottersberger, Hiroyuki Takai, Tatsuya Kibe, Yi Gong, Kaori Takai, Alessandro Bianchi, Michal Zimmermann, Daniel Durocher, Titia de Lange. Nature 2018
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An oligomerized 53BP1 tudor domain suffices for recognition of DNA double-strand breaks.
Omar Zgheib, Kristopher Pataky, Juergen Brugger, Thanos D Halazonetis. Mol Cell Biol 2009
Omar Zgheib, Kristopher Pataky, Juergen Brugger, Thanos D Halazonetis. Mol Cell Biol 2009
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Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways.
I Rappold, K Iwabuchi, T Date, J Chen. J Cell Biol 2001
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BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair.
J Ross Chapman, Alex J Sossick, Simon J Boulton, Stephen P Jackson. J Cell Sci 2012
J Ross Chapman, Alex J Sossick, Simon J Boulton, Stephen P Jackson. J Cell Sci 2012
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Megabase chromatin domains involved in DNA double-strand breaks in vivo.
E P Rogakou, C Boon, C Redon, W M Bonner. J Cell Biol 1999
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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.
Helen E Bryant, Niklas Schultz, Huw D Thomas, Kayan M Parker, Dan Flower, Elena Lopez, Suzanne Kyle, Mark Meuth, Nicola J Curtin, Thomas Helleday. Nature 2005
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TIRR regulates 53BP1 by masking its histone methyl-lysine binding function.
Pascal Drané, Marie-Eve Brault, Gaofeng Cui, Khyati Meghani, Shweta Chaubey, Alexandre Detappe, Nishita Parnandi, Yizhou He, Xiao-Feng Zheng, Maria Victoria Botuyan,[...]. Nature 2017
Pascal Drané, Marie-Eve Brault, Gaofeng Cui, Khyati Meghani, Shweta Chaubey, Alexandre Detappe, Nishita Parnandi, Yizhou He, Xiao-Feng Zheng, Maria Victoria Botuyan,[...]. Nature 2017
12
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.
Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig,[...]. Cell 2018
Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig,[...]. Cell 2018
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Mammalian Rif1 contributes to replication stress survival and homology-directed repair.
Sara B C Buonomo, Yipin Wu, David Ferguson, Titia de Lange. J Cell Biol 2009
Sara B C Buonomo, Yipin Wu, David Ferguson, Titia de Lange. J Cell Biol 2009
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Human CtIP promotes DNA end resection.
Alessandro A Sartori, Claudia Lukas, Julia Coates, Martin Mistrik, Shuang Fu, Jiri Bartek, Richard Baer, Jiri Lukas, Stephen P Jackson. Nature 2007
Alessandro A Sartori, Claudia Lukas, Julia Coates, Martin Mistrik, Shuang Fu, Jiri Bartek, Richard Baer, Jiri Lukas, Stephen P Jackson. Nature 2007
7
53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination.
Anne Bothmer, Davide F Robbiani, Niklas Feldhahn, Anna Gazumyan, Andre Nussenzweig, Michel C Nussenzweig. J Exp Med 2010
Anne Bothmer, Davide F Robbiani, Niklas Feldhahn, Anna Gazumyan, Andre Nussenzweig, Michel C Nussenzweig. J Exp Med 2010
7
53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer.
Richard A DiTullio, Tamara A Mochan, Monica Venere, Jirina Bartkova, Maxwell Sehested, Jiri Bartek, Thanos D Halazonetis. Nat Cell Biol 2002
Richard A DiTullio, Tamara A Mochan, Monica Venere, Jirina Bartkova, Maxwell Sehested, Jiri Bartek, Thanos D Halazonetis. Nat Cell Biol 2002
7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.